Clinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomas

scientific article published on 12 October 2018

Clinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomas is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12020-018-1776-0
P698PubMed publication ID30315484

P50authorMarco LosaQ88448131
P2093author name stringFrancesca Pecori Giraldi
Pietro Mortini
Maria Francesca Cassarino
Angela Pagnano
Mario Detomas
P2860cites workThe Treatment of Cushing's DiseaseQ27010590
Recurrent gain-of-function USP8 mutations in Cushing's diseaseQ35146226
EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomasQ35578652
The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's DiseaseQ35813265
Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice GuidelineQ35916555
Diagnosis and Clinical Genetics of Cushing Syndrome in PediatricsQ36958893
Proopiomelanocortin, glucocorticoid, and CRH receptor expression in human ACTH-secreting pituitary adenomasQ37651359
Quantitative expression profiling of highly degraded RNA from formalin-fixed, paraffin-embedded breast tumor biopsies by oligonucleotide microarrays.Q38427565
The New Molecular Landscape of Cushing's Disease.Q38594142
Somatic USP8 Gene Mutations Are a Common Cause of Pediatric Cushing DiseaseQ38785782
Factors influencing the immediate and late outcome of Cushing's disease treated by transsphenoidal surgery: a retrospective study by the European Cushing's Disease Survey GroupQ40434135
Mutations in the deubiquitinase gene USP8 cause Cushing's diseaseQ41716700
Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society StatementQ42361469
Differential expression of estrogen receptor-beta (ER beta) in human pituitary tumors: functional interactions with ER alpha and a tumor-specific splice variantQ42461358
Desmopressin stimulation test before and after pituitary surgery in patients with Cushing's diseaseQ43674504
Multisystem morbidity and mortality in Cushing's syndrome: a cohort studyQ44767309
Persistent adrenocorticotropin response to desmopressin in the early postoperative period predicts recurrence of Cushing's disease.Q45936676
Outcome of Transsphenoidal Surgery for Cushing Disease: A Single-Center Experience Over 32 YearsQ46893497
Somatic USP8 mutations are frequent events in corticotroph tumor progression causing Nelson's tumorQ47690666
Genetics of Cushing's disease.Q48162581
USP8 Mutations in Pituitary Cushing Adenomas-Targeted Analysis by Next-Generation Sequencing.Q52806299
Expression of epidermal growth factor receptor in neoplastic pituitary cells: evidence for a role in corticotropinoma cells.Q54694108
Gene expression profiling in human corticotroph tumours reveals distinct, neuroendocrine profilesQ58796556
Transforming growth factor-alpha stimulates proliferation of mammotrophs and corticotrophs in the mouse pituitaryQ73790660
Long-term results after microsurgery for Cushing disease: experience with 426 primary operations over 35 yearsQ80441090
Pathogenesis of pituitary tumorsQ83667492
Responses to corticotrophin-releasing hormone and dexamethasone in a large series of human adrenocorticotrophic hormone-secreting pituitary adenomas in vitro reveal manifold corticotroph tumoural phenotypesQ84869446
The USP8 mutational status may predict drug susceptibility in corticotroph adenomas of Cushing's diseaseQ86717911
The USP8 mutational status may predict long-term remission in patients with Cushing's diseaseQ89348567
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)240-246
P577publication date2018-10-12
P1433published inEndocrineQ15757048
P1476titleClinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomas
P478volume63

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cites work (P2860)
Q93127216Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis
Q90540463Genetics of Pituitary Tumours
Q92512997Germline USP8 Mutation Associated With Pediatric Cushing Disease and Other Clinical Features: A New Syndrome
Q90580125Novel insights into Pituitary Tumorigenesis: Genetic and Epigenetic Mechanisms
Q89892586SST5 expression and USP8 mutation in functioning and silent corticotroph pituitary tumors
Q90396537Sexual Dimorphism in Cellular and Molecular Features in Human ACTH-Secreting Pituitary Adenomas
Q92255633The Genetics of Pituitary Adenomas
Q91679876Ubiquitin-Specific Protease 8 Mutant Corticotrope Adenomas Present Unique Secretory and Molecular Features and Shed Light on the Role of Ubiquitylation on ACTH Processing

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