Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis

scientific article published on 04 September 2019

Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/CANCERS11091302
P932PMC publication ID6770943
P698PubMed publication ID31487906

P2093author name stringAlfredo Fusco
Claudio Arra
Daniela D'Angelo
Marco De Martino
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circOMA1-Mediated miR-145-5p Suppresses Tumor Growth of Nonfunctioning Pituitary Adenomas by Targeting TPT1Q91355354
RPSAP52 lncRNA is overexpressed in pituitary tumors and promotes cell proliferation by acting as miRNA sponge for HMGA proteinsQ91932951
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HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activityQ24293207
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Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinomaQ89032142
Alternative processing of mRNAs encoding mammalian chromosomal high-mobility-group proteins HMG-I and HMG-YQ24633159
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Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humansQ24679314
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High mobility group a proteins as tumor markersQ26853205
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
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The prevalence of pituitary adenomas: a systematic reviewQ28273848
In vivo modulation of Hmgic reduces obesityQ28586839
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HMGA1-pseudogene overexpression contributes to cancer progressionQ28608654
HMGA1 pseudogenes as candidate proto-oncogenic competitive endogenous RNAsQ28652432
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Characterization of Gpr101 expression and G-protein coupling selectivityQ33241539
Hmga1/Hmga2 double knock-out mice display a "superpygmy" phenotypeQ33612796
Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma.Q33622368
Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas.Q33896677
Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q.Q33897694
Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutationsQ34030921
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomasQ34135253
Downregulation of HMGA-targeting microRNAs has a critical role in human pituitary tumorigenesisQ34237969
Altered microRNA expression profile in human pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1.Q34273288
Differential expression of microRNAs in GH-secreting pituitary adenomasQ34471255
Advances in understanding pituitary tumorsQ34660143
Recurrent gain-of-function USP8 mutations in Cushing's diseaseQ35146226
EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomasQ35578652
The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's DiseaseQ35813265
Animal models of pituitary neoplasiaQ36486988
The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loopQ36557324
Roles of HMGA proteins in cancerQ37001370
The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer developmentQ37332559
USP8 is a novel target for overcoming gefitinib resistance in lung cancerQ37476722
Role of the high mobility group A proteins in the regulation of pituitary cell cycleQ37706867
In search of a prognostic classification of endocrine pituitary tumorsQ38212659
MicroRNA miR-107 is overexpressed in pituitary adenomas and inhibits the expression of aryl hydrocarbon receptor-interacting protein in vitroQ38323442
The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta geneQ38324299
Methyl-CpG binding column-based identification of nine genes hypermethylated in colorectal cancerQ38336376
Rasd1 is an estrogen-responsive immediate early gene and modulates expression of late genes in rat anterior pituitary cellsQ38694305
Long non-coding RNA C5orf66-AS1 is downregulated in pituitary null cell adenomas and is associated with their invasivenessQ38705928
HMGA1-pseudogene expression is induced in human pituitary tumors.Q38884465
Mir-23b and miR-130b expression is downregulated in pituitary adenomasQ39010323
Aip regulates cAMP signalling and GH secretion in GH3 cellsQ39148181
Overview of the 2017 WHO Classification of Pituitary TumorsQ39190559
Nonfunctioning pituitary adenomas: association of Ki-67 and HMGA-1 labeling indices with residual tumor growthQ39266698
The Dimensions, Dynamics, and Relevance of the Mammalian Noncoding TranscriptomeQ39324991
PIT1 upregulation by HMGA proteins has a role in pituitary tumorigenesisQ39422281
Down-regulation of Wee1 kinase by a specific subset of microRNA in human sporadic pituitary adenomasQ39674297
Analysis of epidermal growth factor receptor and activated epidermal growth factor receptor expression in pituitary adenomas and carcinomasQ40564623
Thyroid cell transformation requires the expression of the HMGA1 proteinsQ40722563
Mutations in the deubiquitinase gene USP8 cause Cushing's diseaseQ41716700
HMGA1P7-pseudogene regulates H19 and Igf2 expression by a competitive endogenous RNA mechanismQ42364945
The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis.Q42809960
E2F1-mediated human POMC expression in ectopic Cushing's syndromeQ42856188
USP8 mutation in Cushing's diseaseQ43200816
Low aryl hydrocarbon receptor-interacting protein expression is a better marker of invasiveness in somatotropinomas than Ki-67 and p53.Q44054768
From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposalQ45054086
Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumorsQ45219910
Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.Q46001664
Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and miceQ46517052
The HMGA1 Pseudogene 7 Induces miR-483 and miR-675 Upregulation by Activating Egr1 through a ceRNA Mechanism.Q47136898
HMGA2 cooperates with either p27(kip1) deficiency or Cdk4(R24C) mutation in pituitary tumorigenesis.Q47382950
Somatic USP8 mutations are frequent events in corticotroph tumor progression causing Nelson's tumorQ47690666
Ubiquitin-specific protease 8 is a novel prognostic marker in early-stage lung adenocarcinoma.Q48096086
Pituitary adenoma predisposition caused by germline mutations in the AIP gene.Q51585727
EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis.Q52738992
USP8 Mutations in Pituitary Cushing Adenomas-Targeted Analysis by Next-Generation Sequencing.Q52806299
Circular RNAs function as ceRNAs to regulate and control human cancer progression.Q53176299
Expression of the long non-coding RNA H19 and MALAT-1 in growth hormone-secreting pituitary adenomas and its relationship to tumor behavior.Q53421523
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.Q53532387
Expression of the long non-coding RNAs MEG3, HOTAIR, and MALAT-1 in non-functioning pituitary adenomas and their relationship to tumor behavior.Q54225798
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.Q54678305
Expression of epidermal growth factor receptor in neoplastic pituitary cells: evidence for a role in corticotropinoma cells.Q54694108
Recent Updates on the Diagnosis and Management of Cushing's Syndrome.Q55387370
Clinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomasQ57470855
Identification of recurrent USP48 and BRAF mutations in Cushing's diseaseQ58793747
SOM230, A New Somatostatin Analogue, Is Highly Effective in the Therapy of Growth Hormone/Prolactin-Secreting Pituitary AdenomasQ59122469
The High Mobility Group A2 gene is amplified and overexpressed in human prolactinomasQ59122644
The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedinQ60322887
High Expression of Ubiquitin-Specific Protease 8 (USP8) Is Associated with Poor Prognosis in Patients with Cervical Squamous Cell Carcinoma.Q64898836
Identification of epidermal growth factor mRNA-expressing cells in the mouse anterior pituitaryQ73576466
Localization of Epidermal Growth Factor (EGF) and Epidermal Growth Factor Receptor (EGFr) in Human Pituitary Adenomas and Nontumorous Pituitaries: An Immunocytochemical StudyQ74453793
Role of Ki-67 proliferation index and p53 expression in predicting progression of pituitary adenomasQ81160827
AIP expression in sporadic somatotropinomas is a predictor of the response to octreotide LAR therapy independent of SSTR2 expressionQ83657187
Pathogenesis of pituitary tumorsQ83667492
Increased expression of HMGA1 correlates with tumour invasiveness and proliferation in human pituitary adenomasQ84202548
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P577publication date2019-09-04
P1433published inCancersQ27722963
P1476titleEmerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis
P478volume11

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