Recurrent gain-of-function USP8 mutations in Cushing's disease

scientific article

Recurrent gain-of-function USP8 mutations in Cushing's disease is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1012450103
P356DOI10.1038/CR.2015.20
P932PMC publication ID4349249
P698PubMed publication ID25675982
P5875ResearchGate publication ID272187232

P50authorChaowei FuQ54357957
Nidan QiaoQ59545034
P2093author name stringYin Wang
Hong Chen
Tao Wang
Juan Zhou
Yi Zhang
Jie Zheng
Ying Mao
Hong Peng
Shan Huang
Zhi-Qiang Li
Yao Zhao
Yong-Fei Wang
Qing-Zhong Wang
Zhao Ye
Li Pan
Shi-Qi Li
Ming Shen
Yong-Yong Shi
Liang-Fu Zhou
Jian-Hua Chen
Ying-Chao Liu
Rong-Gui Hu
Jue Ji
Dai-Zhan Zhou
Dao-Ying Geng
Wei-Min Bao
Yi-Ming Li
Rong Xie
Qi-Lin Zhang
Wei-Jun Tang
Qi-Sheng Tang
Yi-Chao Zhang
Jia-Wei Shen
Wen-Qiang He
Chuan-Xin Huang
Zhao-Yun Zhang
Zhi-Feng Shi
Hong-Ying Ye
Hui-Jia Qiu
Xiao-Lan Qin
Xue-Fei Shou
Zeng-Yi Ma
Zhi-Jian Song
Zu-Jia Wen
P2860cites workExpression of epidermal growth factor receptor in neoplastic pituitary cells: evidence for a role in corticotropinoma cells.Q54694108
Cushing's syndromeQ56228192
Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomasQ59095410
P53 gene mutation in an atypical corticotroph adenoma with Cushing's diseaseQ81930434
UBPY: a growth-regulated human ubiquitin isopeptidase.Q24336064
Regulation of Epidermal Growth Factor Receptor Ubiquitination and Trafficking by the USP8·STAM ComplexQ24621192
Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statementQ24629410
Of old and new diseases: genetics of pituitary ACTH excess (Cushing) and deficiencyQ28242164
Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomesQ28511379
The structural basis for 14-3-3:phosphopeptide binding specificityQ29547190
USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localizationQ34130136
AIP mutation in pituitary adenomas in the 18th century and todayQ34157625
Pituitary adenomas with invasion of the cavernous sinus space: a magnetic resonance imaging classification compared with surgical findingsQ34344241
Syndromes of glucocorticoid resistanceQ34344481
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).Q34381917
The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes.Q34630270
The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice GuidelineQ34760816
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapyQ34763495
Activating mutations of the stimulatory G protein in the McCune-Albright syndromeQ34981177
Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.Q35105992
EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomasQ35578652
USP8 is a novel target for overcoming gefitinib resistance in lung cancerQ37476722
Managing Cushing's disease: the state of the art.Q38177740
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivoQ40142306
Expression and function of sonic hedgehog pathway components in pituitary adenomas: evidence for a direct role in hormone secretion and cell proliferationQ40373963
Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominant-negative glucocorticoid receptor mutation.Q41186916
Mutations in the deubiquitinase gene USP8 cause Cushing's diseaseQ41716700
Clonal origin of pituitary adenomasQ45035533
Corticotroph adenoma of the pituitary in a patient with X-linked adrenal hypoplasia congenita due to a novel mutation of the DAX-1 geneQ46630244
Low expression of the cell cycle inhibitor p27Kip1 in normal corticotroph cells, corticotroph tumors, and malignant pituitary tumorsQ48089950
Clonal origins of adrenocorticotropin-secreting pituitary tissue in Cushing's diseaseQ48415480
A decade of pituitary microsurgery. The Herbert Olivecrona lectureQ48537891
Germline and somatic DICER1 mutations in a pituitary blastoma causing infantile-onset Cushing's disease.Q50471525
Germline AIP mutations in apparently sporadic pituitary adenomas: prevalence in a prospective single-center cohort of 443 patients.Q50967404
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.Q53532387
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P433issue3
P921main subjectCushing's diseaseQ1947304
P304page(s)306-317
P577publication date2015-02-13
P1433published inCell ResearchQ1524018
P1476titleRecurrent gain-of-function USP8 mutations in Cushing's disease
P478volume25

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