CHMP1B is a target of USP8/UBPY regulated by ubiquitin during endocytosis

scientific article published on 22 June 2018

CHMP1B is a target of USP8/UBPY regulated by ubiquitin during endocytosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1007456
P932PMC publication ID6033466
P698PubMed publication ID29933386

P50authorEmmanuel TaillebourgQ56421700
Anne-Claire JacominQ57317926
Marie-Odile FauvarqueQ72227138
Carmen Aguilar-GurrieriQ87233989
Agnès JournetQ89196966
P2093author name stringWinfried Weissenhorn
Emmanuelle Soleilhac
Magda Mortier
Xènia Crespo-Yàñez
P2860cites workThreshold-controlled ubiquitination of the EGFR directs receptor fateQ24296784
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The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulationQ24306674
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Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1BQ24313130
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Structural basis for autoinhibition of ESCRT-III CHMP3Q24318322
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The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradationQ24337922
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Regulation of Epidermal Growth Factor Receptor Ubiquitination and Trafficking by the USP8·STAM ComplexQ24621192
Membrane budding and scission by the ESCRT machinery: it's all in the neckQ24631676
AMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4Q24632729
Systematic and quantitative assessment of the ubiquitin-modified proteomeQ24634631
AMSH is an endosome-associated ubiquitin isopeptidaseQ24676880
EGF receptor trafficking: consequences for signaling and cancerQ27021340
Structural Basis of Ist1 Function and Ist1-Did2 Interaction in the Multivesicular Body Pathway and CytokinesisQ27655663
Structural Basis for ESCRT-III CHMP3 Recruitment of AMSHQ27671639
ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesisQ27932794
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Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomesQ27936225
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Cortical constriction during abscission involves helices of ESCRT-III-dependent filamentsQ28115853
A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKPQ28138440
A genome-wide transgenic RNAi library for conditional gene inactivation in DrosophilaQ28236209
A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomesQ28245757
Subdivision of the Drosophila wing imaginal disc by EGFR-mediated signaling.Q52594675
Control of growth and patterning of the Drosophila wing imaginal disc by EGFR-mediated signaling.Q52594678
The ESCRT machinery regulates the secretion and long-range activity of Hedgehog.Q52783953
Critical role of ESCRT machinery in EGFR recycling.Q54727015
Calpain-7 binds to CHMP1B at its second α-helical region and forms a ternary complex with IST1Q84204517
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors.Q38801542
USP9X Controls EGFR Fate by Deubiquitinating the Endocytic Adaptor Eps15.Q38805248
USP8 modulates ubiquitination of LRIG1 for Met degradationQ38994990
Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases.Q39030641
The Drosophila Chmp1 protein determines wing cell fate through regulation of epidermal growth factor receptor signalingQ39206028
Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membraneQ39244472
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AMSH, an ESCRT-III associated enzyme, deubiquitinates cargo on MVB/late endosomesQ40198309
Stress-specific p38 MAPK activation is sufficient to drive EGFR endocytosis but not its nuclear translocationQ41428507
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Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissuesQ41868492
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UBPY-mediated epidermal growth factor receptor (EGFR) de-ubiquitination promotes EGFR degradationQ42833376
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Loss- and gain-of-function analyses of vacuolar protein sorting 2 in Notch signaling of Drosophila melanogasterQ46421151
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Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradationQ30159469
Interaction of AMSH with ESCRT-III and deubiquitination of endosomal cargoQ30159774
Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machineryQ30159944
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The role of Bro1- domain-containing protein Myopic in endosomal trafficking of Wnt/Wingless.Q32884425
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Membrane fission reactions of the mammalian ESCRT pathwayQ33720525
Structure/function analysis of four core ESCRT-III proteins reveals common regulatory role for extreme C-terminal domainQ34634187
Regulating morphogen gradients in the Drosophila wingQ34749567
Recurrent gain-of-function USP8 mutations in Cushing's diseaseQ35146226
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ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.Q35761996
The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's DiseaseQ35813265
The Myopic-Ubpy-Hrs nexus enables endosomal recycling of FrizzledQ36058465
A functional endosomal pathway is necessary for lysosome biogenesis in Drosophila.Q36194398
Structure and membrane remodeling activity of ESCRT-III helical polymersQ36386351
Ist1 regulates Vps4 localization and assemblyQ36438828
Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filamentsQ36483789
Endocytosis: the DUB versionQ36601432
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutantsQ37248192
USP8 is a novel target for overcoming gefitinib resistance in lung cancerQ37476722
Ubpy controls the stability of the ESCRT-0 subunit Hrs in development.Q37642881
Mechanism of recruitment and activation of the endosome-associated deubiquitinase AMSH.Q37679390
Divergent pathways lead to ESCRT-III-catalyzed membrane fissionQ37804581
Molecular mechanisms of the membrane sculpting ESCRT pathwayQ38134065
Interdependent epidermal growth factor receptor signalling and trafficking.Q38200387
Endosome maturation, transport and functionsQ38202717
Genetics of Cushing's disease: an updateQ38553643
Regulation of Notch Signaling Through Intracellular TransportQ38761353
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCellProfilerQ5058134
P433issue6
P304page(s)e1007456
P577publication date2018-06-22
P1433published inPLOS GeneticsQ1893441
P1476titleCHMP1B is a target of USP8/UBPY regulated by ubiquitin during endocytosis
P478volume14

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