Regulation of endocytic sorting by ESCRT-DUB-mediated deubiquitination

scientific article

Regulation of endocytic sorting by ESCRT-DUB-mediated deubiquitination is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1049897991
P356DOI10.1007/S12013-011-9181-9
P698PubMed publication ID21448666
P5875ResearchGate publication ID50908160

P2093author name stringIlana Berlin
Piers D Nash
Michelle H Wright
P2860cites workPossible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokinesQ22010172
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesisQ24293532
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signallingQ24299573
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulationQ24306674
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20Q24307779
Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase TQ24312706
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complexQ24313604
Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesisQ24317098
Structural basis for autoinhibition of ESCRT-III CHMP3Q24318322
UBPY: a growth-regulated human ubiquitin isopeptidase.Q24336064
The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradationQ24337922
Hrs recruits clathrin to early endosomesQ24535764
The Deubiquitinating Enzyme USP8 Promotes Trafficking and Degradation of the Chemokine Receptor 4 at the Sorting EndosomeQ24569667
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient miceQ24616207
Regulation of Epidermal Growth Factor Receptor Ubiquitination and Trafficking by the USP8·STAM ComplexQ24621192
AMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4Q24632729
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymesQ24645701
Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomesQ24657919
AMSH is an endosome-associated ubiquitin isopeptidaseQ24676880
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathwayQ24678032
Hybrid Structural Model of the Complete Human ESCRT-0 ComplexQ27654065
Structure and Function of the ESCRT-II-III Interface in Multivesicular Body BiogenesisQ27657043
RING domain E3 ubiquitin ligasesQ27860546
A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complexQ28115418
ESCRT-III dysfunction causes autophagosome accumulation and neurodegenerationQ28117494
Breaking the chains: structure and function of the deubiquitinasesQ28131738
Assembly of Cell Regulatory Systems Through Protein Interaction DomainsQ28155799
A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signalingQ28217751
Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomesQ28241658
Modification of proteins by ubiquitin and ubiquitin-like proteinsQ28244250
A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomesQ28245757
Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)Q28268036
G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitizationQ28276743
A genomic and functional inventory of deubiquitinating enzymesQ28284911
Polyubiquitin chains: polymeric protein signalsQ28294396
Mechanism and function of deubiquitinating enzymesQ28295758
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell deathQ29547297
Ubiquitin-binding domains - from structures to functionsQ29614829
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responsesQ29616349
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathwayQ29616746
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteinsQ29617399
Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding ProteinsQ29619145
Parallels between cytokinesis and retroviral budding: a role for the ESCRT machineryQ29619960
The emerging shape of the ESCRT machineryQ29620787
Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodiesQ30159582
Control of growth factor receptor dynamics by reversible ubiquitinationQ30159602
Interaction of AMSH with ESCRT-III and deubiquitination of endosomal cargoQ30159774
Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machineryQ30159944
Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinasesQ32062433
WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradationQ34220865
Frequent inactivation of A20 in B-cell lymphomasQ34607223
Signal transduction and endocytosis: close encounters of many kindsQ34770359
Autophagy and multivesicular bodies: two closely related partnersQ34880346
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative diseaseQ36119653
Endocytosis: the DUB versionQ36601432
ESCRTing proteins in the endocytic pathwayQ36995735
Reverse the curse--the role of deubiquitination in cell cycle controlQ37112275
Bcl-2 family members: dual regulators of apoptosis and autophagyQ37170680
Controlling receptor downregulation by ubiquitination and deubiquitinationQ37184823
Endosomal deubiquitinating enzymes control ubiquitination and down-regulation of protease-activated receptor 2.Q37460026
A new map to understand deubiquitinationQ37674649
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivoQ40142306
Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signalingQ40358414
The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL.Q40445219
Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sortingQ40773765
Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane proteinQ42174399
Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitinationQ42800213
ERBB2 is a target for USP8-mediated deubiquitinationQ42818688
UBPY-mediated epidermal growth factor receptor (EGFR) de-ubiquitination promotes EGFR degradationQ42833376
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I moleculesQ43077741
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.Q53532387
E3 ubiquitin ligasesQ56385740
The soluble leptin receptor is crucial for leptin action: evidence from clinical and experimental dataQ58327118
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)39-46
P577publication date2011-06-01
P1433published inCell Biochemistry and BiophysicsQ15755135
P1476titleRegulation of endocytic sorting by ESCRT-DUB-mediated deubiquitination
P478volume60

Reverse relations

cites work (P2860)
Q89196972CHMP1B is a target of USP8/UBPY regulated by ubiquitin during endocytosis
Q36421773CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
Q38070788Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium
Q30010036Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR.
Q38038634Continuous endocytic recycling of tight junction proteins: how and why?
Q35735068Cullin-3 regulates late endosome maturation.
Q38336126DUBs, the regulation of cell identity and disease
Q58766259Deubiquitinating Enzymes Related to Autophagy: New Therapeutic Opportunities?
Q48526649Dynamic of contribution of UBPy-sorted cargo to acrosome biogenesis: effects of its derailment in a mouse model of globozoospermia, the infertile Vps54 (L967Q) mutant
Q48137297ESCRT-III-Associated Protein ALIX Mediates High-Affinity Phosphate Transporter Trafficking to Maintain Phosphate Homeostasis in Arabidopsis.
Q33356416Endocytic regulation of alkali metal transport proteins in mammals, yeast and plants
Q37940139Endosomal transport via ubiquitination
Q28116849Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders
Q42176889Functional Interaction Between the ESCRT-I Component TSG101 and the HSV-1 Tegument Ubiquitin Specific Protease
Q34437868GLUT4 traffic through an ESCRT-III-dependent sorting compartment in adipocytes.
Q37970436HIV-1, ubiquitin and ubiquitin-like proteins: the dialectic interactions of a virus with a sophisticated network of post-translational modifications
Q53544759High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma.
Q30009835High-throughput compatible fluorescence resonance energy transfer-based assay to identify small molecule inhibitors of AMSH deubiquitinase activity
Q28829301Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition
Q33720525Membrane fission reactions of the mammalian ESCRT pathway
Q24337654Mutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly-capillary malformation syndrome
Q26852269Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases
Q37429858Proteolipid protein-deficient myelin promotes axonal mitochondrial dysfunction via altered metabolic coupling.
Q47112846Regulation of AMPA Receptor Trafficking by Protein Ubiquitination.
Q38120938Regulation of proteolysis by human deubiquitinating enzymes
Q33888529Roles for trafficking and O-linked glycosylation in the turnover of model cell surface proteins
Q90601708Salvianolic acid A inhibits tumor-associated angiogenesis by blocking GRP78 secretion
Q27672914Structural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different Stability
Q28566070Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8
Q96303690The Beginning of the End: Initial Steps in the Degradation of Plasma Membrane Proteins
Q51043397The ESCRT-deubiquitinating enzyme USP8 in the cervical spinal cord of wild-type and Vps54-recessive (wobbler) mutant mice.
Q26828378The role of deubiquitinating enzymes in synaptic function and nervous system diseases
Q40691827The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells
Q88595417USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels
Q42910235USP8--Another DUB in the T cell club
Q26865244Ubiquitin Lys 63 chains - second-most abundant, but poorly understood in plants
Q91679876Ubiquitin-Specific Protease 8 Mutant Corticotrope Adenomas Present Unique Secretory and Molecular Features and Shed Light on the Role of Ubiquitylation on ACTH Processing
Q38175272Ubiquitin-dependent sorting in endocytosis
Q36635913Ubiquitin-specific peptidase 8 (USP8) regulates endosomal trafficking of the epithelial Na+ channel
Q37679191Ubiquitination regulates the morphogenesis and function of sperm organelles
Q26766480Vesicular Trafficking to the Immune Synapse: How to Assemble Receptor-Tailored Pathways from a Basic Building Set

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