Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease

scientific article published on 06 November 2018

Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JNEUMETH.2018.11.005
P932PMC publication ID6451872
P698PubMed publication ID30412730

P2093author name stringSteven W Barger
Robert J Shmookler Reis
Srinivas Ayyadevara
Meenakshisundaram Balasubramaniam
Akshatha Ganne
Rachel D Hendrix
P2860cites workProteostasis and neurodegeneration: the roles of proteasomal degradation and autophagyQ26998515
Inflammation, defective insulin signaling, and mitochondrial dysfunction as common molecular denominators connecting type 2 diabetes to Alzheimer diseaseQ27021770
Damaging effects of a high-fat diet to the brain and cognition: a review of proposed mechanismsQ27023109
Systematic functional analysis of the Caenorhabditis elegans genome using RNAiQ27860839
High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents.Q30374931
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Obesity in middle age and future risk of dementia: a 27 year longitudinal population based studyQ33941073
Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespanQ34048746
Dietary fat intake and the risk of incident dementia in the Rotterdam StudyQ34065622
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Mitochondrial DNA damage and dysfunction, and oxidative stress are associated with endoplasmic reticulum stress, protein degradation and apoptosis in high fat diet-induced insulin resistance miceQ34559096
Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexesQ35080559
Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization: lessons learnt from laron syndromeQ35121240
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive declineQ35858095
The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer diseaseQ36119393
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Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of ratsQ42904879
A cascade of protein aggregation bombards mitochondria for neurodegeneration and apoptosis under WWOX deficiencyQ43167142
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Endocrine alterations and signaling changes associated with declining ovarian function and advanced biological aging in follicle-stimulating hormone receptor haploinsufficient mice.Q44075554
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Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.Q45305673
Endoplasmic reticulum stress plays a central role in development of leptin resistanceQ46178586
Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifsQ47747182
[Glucose tolerance status and risk of dementia in the community: the Hisayama study].Q51340177
Decreased hepatic phosphatidylinositol-3,4,5-triphosphate (PIP3) levels and impaired glucose homeostasis in type 1 and type 2 diabetic rats.Q54474557
P407language of work or nameEnglishQ1860
P921main subjectneurodegenerationQ1755122
P304page(s)40-46
P577publication date2018-11-06
P1433published inJournal of Neuroscience MethodsQ15764020
P1476titleFunctional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'
P478volume319

Reverse relations

Q64104414The Role of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Nervous Systemcites workP2860

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