Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance

Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2018.07.067
P932PMC publication ID6142813
P698PubMed publication ID30134172

P50authorThomas F. GajewskiQ88137719
P2093author name stringYing Wang
Maria-Luisa Alegre
James J Moon
Michelle L Miller
Anita S Chong
Jason B Williams
Christine M McIntosh
Maile K Hollinger
Noel J Isaad
P2860cites workRecruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptorQ28595009
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Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibodyQ33887941
CD8 binding to MHC class I molecules is influenced by T cell maturation and glycosylationQ34106394
Vaccines with enhanced costimulation maintain high avidity memory CTL.Q34312218
The molecular and functional characterization of a dominant minor H antigen, H60.Q34473903
Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patternsQ34507271
IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunizationQ34581324
Peak Studio: a tool for the visualization and analysis of fragment analysis filesQ34769026
Listeria-based vaccines can overcome tolerance by expanding low avidity CD8+ T cells capable of eradicating a solid tumor in a transgenic mouse model of cancerQ34797653
An anti-CD154 domain antibody prolongs graft survival and induces Foxp3(+) iTreg in the absence and presence of CTLA-4 Ig.Q34870978
Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cellsQ35197906
Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8(+) T LymphocytesQ35683291
Multiple costimulatory modalities enhance CTL avidityQ35901490
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancerQ36260673
T cell affinity maturation by selective expansion during infectionQ36367796
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Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.Q36383089
Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo.Q36400871
Quantitative theories of T-cell responsivenessQ36762522
Avidity maturation of memory CD8 T cells is limited by self-antigen expressionQ36851911
Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domainQ37106769
Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.Q37382702
Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against AutoimmunityQ37413039
pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansionQ37415209
Direct T cell activation via CD40 ligand generates high avidity CD8+ T cells capable of breaking immunological tolerance for the control of tumorsQ37659577
Apoptosis-regulated low-avidity cancer-specific CD8(+) T cells can be rescued to eliminate HER2/neu-expressing tumors by costimulatory agonists in tolerized miceQ37725761
Delayed Cytotoxic T Lymphocyte-Associated Protein 4-Immunoglobulin Treatment Reverses Ongoing Alloantibody Responses and Rescues Allografts From Acute RejectionQ38416698
Tracking of TCR-Transgenic T Cells Reveals That Multiple Mechanisms Maintain Cardiac Transplant Tolerance in MiceQ39289936
Priming of a novel subset of CD28+ rapidly expanding high-avidity effector memory CTL by post maturation electroporation-CD40L dendritic cells is IL-12 dependentQ39932974
Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytesQ40002355
Adoptive Transfer of Tracer-Alloreactive CD4+ T Cell Receptor Transgenic T Cells Alters the Endogenous Immune Response to an AllograftQ40720995
Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers.Q40974006
A kinetic basis for T cell receptor repertoire selection during an immune responseQ41649927
Complete but curtailed T-cell response to very low-affinity antigenQ41902378
Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant stateQ42265378
Functional differences between low- and high-affinity CD8(+) T cells in the tumor environmentQ42403156
Mycophenolic acid impedes the antigen presenting and lymph node homing capacities of human blood myeloid dendritic cellsQ43288507
V beta 5+ T cell receptors skew toward OVA+H-2Kb recognitionQ43516685
Cell cycle block in anergic T cells during tolerance inductionQ44393721
The potency of allospecific Tregs cells appears to correlate with T cell receptor functional avidity.Q44781094
The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate.Q46003771
Chromatin states define tumour-specific T cell dysfunction and reprogramming.Q46060358
Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexesQ47877315
Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory.Q50930669
Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation.Q51815669
Allospecific CD4(+) T cells retain effector function and are actively regulated by Treg cells in the context of transplantation tolerance.Q52945700
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.Q54073234
Equal Expansion of Endogenous Transplant-Specific Regulatory T Cell and Recruitment Into the Allograft During Rejection and Tolerance.Q55433915
Detection of self-reactive CD8⁺ T cells with an anergic phenotype in healthy individualsQ56896508
Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent mannerQ56906395
Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4+ T cell response to a rheumatoid arthritis-associated antigenQ56922039
Tumor-Specific CD4+ T Cells Render the Tumor Environment Permissive for Infiltration by Low-Avidity CD8+ T CellsQ61140251
Heterogeneity of T cell clones specific for a single indirect alloantigenic epitope (I-Ab/H-2Kd54-68) that mediate transplant rejectionQ73299684
Enhanced surface TCR replenishment mediated by CD28 leads to greater TCR engagement during primary stimulationQ73849980
Caveats in the design of MHC class I tetramer/antigen-specific T lymphocytes dissociation assaysQ73937582
Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejectionQ93747372
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)2112-2126
P577publication date2018-08-21
P1433published inCell ReportsQ5058165
P1476titleDistinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance
P478volume24

Reverse relations

cites work (P2860)
Q92547560Eosinophils downregulate lung alloimmunity by decreasing TCR signal transduction
Q90080933Exploiting immunometabolism and T cell function for solid organ transplantation
Q91559975The pursuit of transplantation tolerance: new mechanistic insights
Q93052070Tolerating Factor VIII: Recent Progress