| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1034171973 |
| P356 | DOI | 10.1038/NATURE07657 |
| P932 | PMC publication ID | 2735344 |
| P698 | PubMed publication ID | 19182777 |
| P5875 | ResearchGate publication ID | 23964623 |
| P2093 | author name string | Michael J Bevan | |
| Dietmar Zehn | |||
| Sarah Y Lee | |||
| P2860 | cites work | TCR affinity and negative regulation limit autoimmunity | Q57184989 |
| Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR | Q74286685 | ||
| Estimating the precursor frequency of naive antigen-specific CD8 T cells | Q24674109 | ||
| Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition | Q28282470 | ||
| In situ imaging of the endogenous CD8 T cell response to infection | Q30493909 | ||
| Specificity and degeneracy of T cells | Q33199993 | ||
| Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes | Q33808561 | ||
| Positive and negative selection of T cells | Q34157557 | ||
| Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors | Q34315765 | ||
| Effector and memory CTL differentiation | Q34584974 | ||
| Immune responses to Listeria monocytogenes | Q35906097 | ||
| Initial T cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T cell response to infection. | Q36008100 | ||
| The role of models in understanding CD8+ T-cell memory | Q36015867 | ||
| Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor | Q36082833 | ||
| Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection | Q36202704 | ||
| Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation | Q36229041 | ||
| A coordinated change in chemokine responsiveness guides plasma cell movements | Q36369352 | ||
| Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates | Q36509866 | ||
| Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunity | Q36528984 | ||
| Structural determinants of T-cell receptor bias in immunity | Q36655911 | ||
| T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation | Q37233655 | ||
| Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling | Q39773899 | ||
| T-cell-receptor affinity and thymocyte positive selection | Q41192128 | ||
| Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection | Q43456947 | ||
| The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells | Q45037389 | ||
| A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets. | Q51968727 | ||
| P433 | issue | 7235 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 211-214 | |
| P577 | publication date | 2009-01-28 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Complete but curtailed T-cell response to very low-affinity antigen | |
| P478 | volume | 458 |
| Q30379637 | 25 years of HIV research! ... and what about a vaccine? |
| Q58122065 | 2D Kinetic Analysis of TCR and CD8 Coreceptor for LCMV GP33 Epitopes |
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| Q37368692 | A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire. |
| Q48241399 | A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses |
| Q36762618 | A T-cell response to a liver-stage Plasmodium antigen is not boosted by repeated sporozoite immunizations |
| Q42775633 | A mathematical model of immune activation with a unified self-nonself concept |
| Q39942708 | A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet. |
| Q38513499 | A septin requirement differentiates autonomous and contact-facilitated T cell proliferation |
| Q34144494 | A sharp T-cell antigen receptor signaling threshold for T-cell proliferation |
| Q38831678 | Adhesion- and Degranulation-Promoting Adapter Protein Promotes CD8 T Cell Differentiation and Resident Memory Formation and Function during an Acute Infection. |
| Q27675301 | Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses |
| Q35566596 | Altered differentiation, diminished pathogenicity, and regulatory activity of myelin-specific T cells expressing an enhanced affinity TCR. |
| Q41980961 | Anti-TCRβ mAb induces long-term allograft survival by reducing antigen-reactive T cells and sparing regulatory T cells. |
| Q41916666 | Antigen availability determines CD8⁺ T cell-dendritic cell interaction kinetics and memory fate decisions |
| Q33835059 | Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses |
| Q37352687 | Antigen-affinity controls pre-germinal centser B cell selection by promoting Mcl-1 induction through BAFF receptor signaling. |
| Q37038797 | Antigen-free adjuvant assists late effector CD4 T cells to transit to memory in lymphopenic hosts |
| Q36866247 | Antigen-stimulated CD4 T cell expansion can be limited by their grazing of peptide-MHC complexes |
| Q34602386 | Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number. |
| Q37801271 | Antigen‐driven T‐cell repertoire selection during adaptive immune responses |
| Q33723518 | Assessment of bivalent and tetravalent dengue vaccine formulations in flavivirus-naïve adults in Mexico |
| Q33698019 | Attenuated T cell responses to a high-potency ligand in vivo |
| Q91886028 | Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts |
| Q37548431 | Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells. |
| Q36278041 | Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection. |
| Q35875258 | Bi-Allelic TCRα or β Recombination Enhances T Cell Development but Is Dispensable for Antigen Responses and Experimental Autoimmune Encephalomyelitis. |
| Q37082145 | Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes. |
| Q28506762 | Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner |
| Q90042544 | CART cells are prone to Fas- and DR5-mediated cell death |
| Q59360810 | CD4 T Cell Affinity Diversity Is Equally Maintained during Acute and Chronic Infection |
| Q40467071 | CD40L expression by CD4+ but not CD8+ T cells regulates antiviral immune responses in acute LCMV infection in mice. |
| Q89548665 | CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence |
| Q35038836 | CD8 T Cells and Toxoplasma gondii: A New Paradigm |
| Q37308236 | CD8+ T cell immunodominance shifts during the early stages of acute LCMV infection independently from functional avidity maturation |
| Q37543246 | CTL quality and the control of human retroviral infections |
| Q91638872 | CTL-Derived Exosomes Enhance the Activation of CTLs Stimulated by Low-Affinity Peptides |
| Q59800421 | Cheating the Hunger Games; Mechanisms Controlling Clonal Diversity of CD8 Effector and Memory Populations |
| Q55291526 | Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes. |
| Q35683291 | Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8(+) T Lymphocytes |
| Q95327696 | Clonal expansion of innate and adaptive lymphocytes |
| Q41440201 | Competition between T cells maintains clonal dominance during memory inflation induced by MCMV. |
| Q37790058 | Considerations in the design of vaccines that induce CD8 T cell mediated immunity |
| Q37116126 | Continuous Effector CD8(+) T Cell Production in a Controlled Persistent Infection Is Sustained by a Proliferative Intermediate Population |
| Q36717167 | Control of T cell antigen reactivity via programmed TCR downregulation. |
| Q34320450 | Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire |
| Q47557087 | Critical Interactions between Immunogenic Cancer Cell Death, Oncolytic Viruses, and the Immune System Define the Rational Design of Combination Immunotherapies |
| Q37760422 | Cross-priming in health and disease. |
| Q35763482 | Cutting Edge: Caspase-11 Limits the Response of CD8+ T Cells to Low-Abundance and Low-Affinity Antigens |
| Q41822388 | Cutting edge: CD8+ recent thymic emigrants exhibit increased responses to low-affinity ligands and improved access to peripheral sites of inflammation |
| Q47619072 | DNA Vaccination by Electroporation Amplifies Broadly Cross-Restricted Public TCR Clonotypes Shared with HIV Controllers |
| Q64237423 | DNA-Barcoded pMHC Tetramers for Detection of Single Antigen-Specific T Cells by Digital PCR |
| Q30761086 | DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity |
| Q34568402 | Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses |
| Q27324746 | Defining immune engagement thresholds for in vivo control of virus-driven lymphoproliferation |
| Q38069828 | Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection |
| Q92118459 | Deletion of PTPN22 improves effector and memory CD8+ T cell responses to tumors |
| Q39349502 | Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen. |
| Q28079616 | Diacylglycerol Kinases in T Cell Tolerance and Effector Function |
| Q36820360 | Diacylglycerol kinases: regulated controllers of T cell activation, function, and development |
| Q42212744 | Different TCR-induced T lymphocyte responses are potentiated by stiffness with variable sensitivity |
| Q35785549 | Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases |
| Q35216990 | Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8+ T cells |
| Q39978090 | Direct measurement of T cell receptor affinity and sequence from naïve antiviral T cells |
| Q34077092 | Direct presentation regulates the magnitude of the CD8+ T cell response to cell-associated antigen through prolonged T cell proliferation |
| Q36066378 | Distinct CD4+ helper T cells involved in primary and secondary responses to infection. |
| Q58726665 | Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance |
| Q47913732 | Distinct PKC-mediated posttranscriptional events set cytokine production kinetics in CD8+ T cells |
| Q30504688 | Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses |
| Q37508408 | Diversity in CD8(+) T cell differentiation. |
| Q40528836 | Dok-1 and Dok-2 Regulate the Formation of Memory CD8+ T Cells |
| Q35175877 | Duration of antigen availability influences the expansion and memory differentiation of T cells |
| Q89548744 | Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells |
| Q99350221 | Dysfunction of CD8 + PD-1 + T cells in type 2 diabetes caused by the impairment of metabolism-immune axis |
| Q38208821 | Early Decision: Effector and Effector Memory T Cell Differentiation in Chronic Infection |
| Q101237609 | Early emergence of T central memory precursors programs clonal dominance during chronic viral infection |
| Q34381605 | Early signals during CD8 T cell priming regulate the generation of central memory cells |
| Q28709263 | Ecological analysis of antigen-specific CTL repertoires defines the relationship between naive and immune T-cell populations |
| Q34469408 | Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. |
| Q34462786 | Efficient help for autoreactive B-cell activation requires CD4+ T-cell recognition of an agonist peptide at the effector stage |
| Q89495144 | Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location |
| Q39535048 | Enhanced Requirement for TNFR2 in Graft Rejection Mediated by Low-Affinity Memory CD8+ T Cells during Heterologous Immunity. |
| Q36562605 | Enhanced function of redirected human T cells expressing linker for activation of T cells that is resistant to ubiquitylation |
| Q90390406 | Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity |
| Q33741881 | Epitope Density Influences CD8+ Memory T Cell Differentiation |
| Q33993575 | Evolution of the antigen-specific CD8+ TCR repertoire across the life span: evidence for clonal homogenization of the old TCR repertoire |
| Q64080867 | Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome |
| Q35008485 | Expression of chemokine receptor CXCR3 on T cells affects the balance between effector and memory CD8 T-cell generation |
| Q54210134 | Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells. |
| Q30498244 | Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number. |
| Q34082904 | Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells |
| Q38925984 | Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR α- and β-chain diversity in the face of peptide-MHC class I specificity |
| Q37727632 | From the thymus to longevity in the periphery. |
| Q90660775 | Frontline Science: PECAM-1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells |
| Q37646737 | Functional anatomy of T cell activation and synapse formation |
| Q38066211 | Functional avidity: a measure to predict the efficacy of effector T cells? |
| Q42403156 | Functional differences between low- and high-affinity CD8(+) T cells in the tumor environment |
| Q37518497 | Functional implications of T cell receptor diversity |
| Q36012164 | Gads regulates the expansion phase of CD8+ T cell-mediated immunity |
| Q35244714 | Generating CD8 T cell heterogeneity: attack of the clones |
| Q90455147 | Going Native: Synthesis of Glycoproteins and Glycopeptides via Native Linkages To Study Glycan-Specific Roles in the Immune System |
| Q42218298 | Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection |
| Q33535905 | HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity |
| Q37695291 | Heterogeneity assessment of functional T cell avidity. |
| Q44758058 | Heterogeneous differentiation patterns of individual CD8+ T cells. |
| Q34159981 | Heterologous immunity: immunopathology, autoimmunity and protection during viral infections. |
| Q37197889 | High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival |
| Q37452503 | High frequencies of virus-specific CD8+ T-cell precursors |
| Q34501474 | High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses |
| Q92024558 | Human leukocyte antigen susceptibility map for SARS-CoV-2 |
| Q88978505 | Human leukocyte antigen susceptibility map for SARS-CoV-2 |
| Q33476079 | Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells |
| Q51018338 | Hyaluronan binding identifies the most proliferative activated and memory T cells. |
| Q50909156 | IL-12-mediated STAT4 signaling and TCR signal strength cooperate in the induction of CD40L in human and mouse CD8+ T cells. |
| Q96126792 | IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses |
| Q45907616 | IRF4 links antigen affinity to CD8+ T-cell metabolism. |
| Q26774669 | Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens |
| Q38000487 | IgM memory B cells: a mouse/human paradox. |
| Q54676825 | Illuminating the petite picture of T cell memory responses to Listeria monocytogenes. |
| Q38577713 | Immune Memory and Exhaustion: Clinically Relevant Lessons from the LCMV Model |
| Q99240741 | Immune literacy: reading, writing and editing adaptive immunity |
| Q35928216 | Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery |
| Q37773295 | Immunodrugs: breaking B- but not T-cell tolerance with therapeutic anticytokine vaccines |
| Q37866369 | Immunologic considerations for generating memory CD8 T cells through vaccination. |
| Q41935553 | Immunological tolerance to LCMV antigens differently affects control of acute and chronic virus infection in mice. |
| Q41012572 | Immunotherapy Expands and Maintains the Function of High-Affinity Tumor-Infiltrating CD8 T Cells In Situ |
| Q58575896 | Immunotherapy for non-small cell lung cancers: biomarkers for predicting responses and strategies to overcome resistance |
| Q38601426 | Impact of Depleting Therapeutic Monoclonal Antibodies on the Host Adaptive Immunity: A Bonus or a Malus? |
| Q37634253 | Improving T cell responses to modified peptides in tumor vaccines |
| Q90239751 | In Vivo Function of the Lipid Raft Protein Flotillin-1 during CD8+ T Cell-Mediated Host Surveillance |
| Q27012849 | Indoctrinating T cells to attack pathogens through homeschooling |
| Q37520229 | Inflammation and TCR signal strength determine the breadth of the T cell response in a bim-dependent manner. |
| Q89788065 | Inhibition of SHP-1 Expands the Repertoire of Antitumor T Cells Available to Respond to Immune Checkpoint Blockade |
| Q37374912 | Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation |
| Q49361458 | Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity. |
| Q37189299 | Interrogating the relationship between naïve and immune antiviral T cell repertoires |
| Q37620444 | Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC. |
| Q59355779 | Irf3 from mandarin fish thymus initiates interferon transcription |
| Q64067638 | Is TCR/pMHC Affinity a Good Estimate of the T-cell Response? An Answer Based on Predictions From 12 Phenotypic Models |
| Q57310383 | Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding |
| Q40487156 | Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands |
| Q64955683 | LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling. |
| Q34313815 | Lack of original antigenic sin in recall CD8(+) T cell responses |
| Q59357739 | Lifelong CMV infection improves immune defense in old mice by broadening the mobilized TCR repertoire against third-party infection |
| Q36094879 | Loss of DRAK2 signaling enhances allogeneic transplant survival by limiting effector and memory T cell responses |
| Q36655788 | Low-Affinity Memory CD8+ T Cells Mediate Robust Heterologous Immunity. |
| Q37585705 | Low-affinity CD4+ T cells are major responders in the primary immune response |
| Q26781296 | Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response |
| Q51047946 | Lowering TCR expression on naive CD8+ T cells does not affect memory T-cell differentiation. |
| Q37486804 | Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression |
| Q33838467 | Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE. |
| Q38691482 | Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation |
| Q89598289 | Mechanotransduction in T Cell Development, Differentiation and Function |
| Q37892595 | Melanoma vaccines: developments over the past 10 years. |
| Q34060493 | Memories that last forever: strategies for optimizing vaccine T-cell memory |
| Q37576718 | Memory CD8+ T cells exhibit increased antigen threshold requirements for recall proliferation |
| Q36018535 | Memory programming in CD8(+) T-cell differentiation is intrinsic and is not determined by CD4 help |
| Q49464460 | Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation |
| Q37828371 | Metabolism, migration and memory in cytotoxic T cells |
| Q37210788 | MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer |
| Q38152795 | Mobilizing and evaluating anticancer T cells: pitfalls and solutions. |
| Q48021856 | Modeling the effect of boost timing in murine irradiated sporozoite prime-boost vaccines. |
| Q48338497 | Modulation of Naive CD8 T Cell Response Features by Ligand Density, Affinity, and Continued Signaling via Internalized TCRs. |
| Q38117139 | Molecular insights for optimizing T cell receptor specificity against cancer |
| Q36977064 | Monitoring the Dynamics of T Cell Clonal Diversity Using Recombinant Peptide:MHC Technology |
| Q64259781 | Mouse Models of Heterologous Flavivirus Immunity: A Role for Cross-Reactive T Cells |
| Q38370894 | Moving to the suburbs: T-cell positioning within lymph nodes during activation and memory. |
| Q38772796 | Mucosal memory CD8⁺ T cells are selected in the periphery by an MHC class I molecule |
| Q33653495 | Multiple innate signaling pathways cooperate with CD40 to induce potent, CD70-dependent cellular immunity |
| Q42159579 | Murine superficial lymph node surgery |
| Q41125629 | Myc or no Myc, that is the question |
| Q36973687 | N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8+ T cell memory but not to effector differentiation |
| Q36813461 | NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen response |
| Q33840153 | Naturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency |
| Q37782409 | Nature and nurture: T-cell receptor-dependent and T-cell receptor-independent differentiation cues in the selection of the memory T-cell pool. |
| Q26770670 | Naïve T Cell Homeostasis Regulated by Stress Responses and TCR Signaling |
| Q30156064 | Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire |
| Q35182373 | Nondominant CD8 T cells are active players in the vaccine-induced antitumor immune response |
| Q33902414 | One naive T cell, multiple fates in CD8+ T cell differentiation. |
| Q39759757 | Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice. |
| Q34661042 | Optimal T-cell receptor affinity for inducing autoimmunity |
| Q64123715 | Optimized Peptide-MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells |
| Q52731749 | Overcoming resistance to anti-PD immunotherapy in a syngeneic mouse lung cancer model using locoregional virotherapy. |
| Q43267507 | Oxidative stress can alter the antigenicity of immunodominant peptides |
| Q36569381 | Pathogen-specific inflammatory milieux tune the antigen sensitivity of CD8(+) T cells by enhancing T cell receptor signaling |
| Q88333970 | Peptide Vaccine Formulation Controls the Duration of Antigen Presentation and Magnitude of Tumor-Specific CD8+ T Cell Response |
| Q52730243 | Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations. |
| Q37464168 | Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions. |
| Q34070814 | Persistence of viral infection despite similar killing efficacy of antiviral CD8(+) T cells during acute and chronic phases of infection |
| Q36745336 | Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion |
| Q33849372 | Perspectives for computer modeling in the study of T cell activation |
| Q41981684 | Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation |
| Q54976860 | Phosphoinositide 3-kinase δ inhibition promotes antitumor responses but antagonizes checkpoint inhibitors. |
| Q34643623 | Piecing together the family portrait of TCR-CD3 complexes |
| Q37763999 | Plasticity in programming of effector and memory CD8 T-cell formation |
| Q34318203 | Polyfunctional type-1, -2, and -17 CD8⁺ T cell responses to apoptotic self-antigens correlate with the chronic evolution of hepatitis C virus infection |
| Q37420442 | Postarrest stalling rather than crawling favors CD8(+) over CD4(+) T-cell migration across the blood-brain barrier under flow in vitro |
| Q59357637 | Potential killers exposed: tracking endogenous influenza-specific CD8 T cells |
| Q90641575 | Pre-existing heterologous T-cell immunity and neoantigen immunogenicity |
| Q64252637 | Precise tuning of gene expression levels in mammalian cells |
| Q33676513 | Predominant clonal accumulation of CD8+ T cells with moderate avidity in the central nervous systems of Theiler's virus-infected C57BL/6 mice |
| Q60957167 | Preproinsulin Designer Antigens Excluded from Endoplasmic Reticulum Suppressed Diabetes Development in NOD Mice by DNA Vaccination |
| Q33882912 | Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion |
| Q35890964 | Priming with very low-affinity peptide ligands gives rise to CD8(+) T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression |
| Q37019903 | Pro-inflammatory self-reactive T cells are found within murine TCR-αβ(+) CD4(-) CD8(-) PD-1(+) cells. |
| Q52327552 | Programmed self-assembly of peptide-major histocompatibility complex for antigen-specific immune modulation. |
| Q34136306 | Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate |
| Q33964275 | Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells |
| Q38642919 | Protein kinase D2 is a digital amplifier of T cell receptor-stimulated diacylglycerol signaling in naïve CD8⁺ T cells |
| Q36806548 | Quantifying T lymphocyte turnover |
| Q44774770 | Rapid recruitment and activation of CD8+ T cells after herpes simplex virus type 1 skin infection |
| Q28080312 | Recent advances in T-cell engineering for use in immunotherapy |
| Q95323063 | Recent insights of T cell receptor-mediated signaling pathways for T cell activation and development |
| Q43281147 | Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient |
| Q64118079 | Regulation of T cell expansion by antigen presentation dynamics |
| Q51013924 | Regulators of T-cell memory generation: TCR signals versus CD4+ help? |
| Q58693818 | Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny |
| Q50930669 | Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory. |
| Q36559497 | Repeated exposure to trace amounts of woodchuck hepadnavirus induces molecularly evident infection and virus-specific T cell response in the absence of serological infection markers and hepatitis |
| Q37544031 | Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection |
| Q47106114 | Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22. |
| Q90606946 | Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection |
| Q30389274 | Role of CD8(+) T-cell immunity in influenza infection: potential use in future vaccine development |
| Q38078934 | Role of PI3K/Akt signaling in memory CD8 T cell differentiation |
| Q51404357 | S1P1 downregulation tailors CD8+ T-cell residence time in lymph nodes to the strength of the antigenic stimulation. |
| Q34307579 | SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells |
| Q36638160 | SHP-1 phosphatase activity counteracts increased T cell receptor affinity |
| Q90182358 | Selective inhibition of low-affinity memory CD8+ T cells by corticosteroids |
| Q37809744 | Shaping the T-cell repertoire in the periphery |
| Q37808101 | Shaping the T‐cell repertoire: a matter of life and death |
| Q35903157 | Signal integration by Akt regulates CD8 T cell effector and memory differentiation. |
| Q36120402 | Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest |
| Q38602553 | Sizing up the key determinants of the CD8(+) T cell response |
| Q30433067 | Stimulation of naive CD8+ T cells by a variant viral epitope induces activation and enhanced apoptosis |
| Q94932167 | Stimulation strength controls the rate of initiation but not the molecular organization of TCR-induced signalling |
| Q33716990 | Stochastic models of lymphocyte proliferation and death |
| Q28603191 | Strategic Priming with Multiple Antigens can Yield Memory Cell Phenotypes Optimized for Infection with Mycobacterium tuberculosis: A Computational Study |
| Q92216465 | Strength of T cell signaling regulates HIV-1 replication and establishment of latency |
| Q37866944 | Strength of TCR-peptide/MHC interactions and in vivo T cell responses |
| Q50282444 | Strong TCR-mediated signals suppress integrated stress responses induced by KDELR1 deficiency in naive T cells. |
| Q88645938 | Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells |
| Q38684447 | Suboptimal T-cell receptor signaling compromises protein translation, ribosome biogenesis, and proliferation of mouse CD8 T cells |
| Q41862429 | Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cells |
| Q37236631 | Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ. |
| Q38566464 | Synchronizing transcriptional control of T cell metabolism and function |
| Q55195081 | T Cell Receptor-Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103+ Memory Status of CD8 T Cells in the Brain. |
| Q35893938 | T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens |
| Q26765917 | T Cells and Gene Regulation: The Switching On and Turning Up of Genes after T Cell Receptor Stimulation in CD8 T Cells |
| Q39757065 | T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology |
| Q34115960 | T cell avidity and tumor immunity: problems and solutions |
| Q57235281 | T cell cytolytic capacity is independent of initial stimulation strength |
| Q24297041 | T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice |
| Q35213550 | T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse |
| Q27025087 | T cell responses to antigen: hasty proposals resolved through long engagements |
| Q36646448 | T cell-intrinsic S1PR1 regulates endogenous effector T-cell egress dynamics from lymph nodes during infection. |
| Q36359499 | T cells compete by cleaving cell surface CD27 and blocking access to CD70-bearing APCs |
| Q37693754 | T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks |
| Q50957253 | T inflammatory memory CD8 T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production. |
| Q36799229 | T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy |
| Q37986219 | T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice |
| Q90317657 | T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate |
| Q34541692 | T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool |
| Q37434149 | T-cell stimuli independently sum to regulate an inherited clonal division fate. |
| Q42212300 | TCR Signaling Emerges from the Sum of Many Parts |
| Q26772341 | TCR Signaling in T Cell Memory |
| Q52738758 | TCR Signaling: Mechanisms of Initiation and Propagation. |
| Q38279985 | TCR signal quantity and quality in CD4(+) T cell differentiation. |
| Q38004926 | TCR signaling requirements for activating T cells and for generating memory |
| Q33605976 | TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection |
| Q36049350 | TGF-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation |
| Q40731929 | Target Density, Not Affinity or Avidity of Antigen Recognition, Determines Adoptive T Cell Therapy Outcomes in a Mouse Lymphoma Model. |
| Q37342952 | Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies. |
| Q92091538 | Targeting cancers through TCR-peptide/MHC interactions |
| Q37353924 | Temporary CXCR3 and CCR5 antagonism following vaccination enhances memory CD8 T cell immune responses |
| Q37415052 | ThPOK derepression is required for robust CD8 T cell responses to viral infection |
| Q37527841 | The Capacity To Induce Cross-Presentation Dictates the Success of a TLR7 Agonist-Conjugate Vaccine for Eliciting Cellular Immunity |
| Q33698006 | The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design |
| Q99637295 | The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies |
| Q34734561 | The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens |
| Q40481911 | The Vast Universe of T Cell Diversity: Subsets of Memory Cells and Their Differentiation. |
| Q53673922 | The clinical potential for koff-rate measurement in adoptive immunotherapy. |
| Q37830730 | The descent of memory T cells. |
| Q38034268 | The fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes. |
| Q35025500 | The impact of KLF2 modulation on the transcriptional program and function of CD8 T cells |
| Q41981778 | The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8⁺ T cell responses |
| Q42227293 | The influenza virus-specific CTL immunodominance hierarchy in mice is determined by the relative frequency of high-avidity T cells |
| Q38100061 | The integration of T cell migration, differentiation and function |
| Q34078621 | The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. |
| Q38000057 | The origin of diversity: studying the evolution of multi-faceted CD8+ T cell responses |
| Q37724035 | The persistence of T cell memory. |
| Q51891099 | The precursors of memory: models and controversies. |
| Q36673657 | The requirement of linker for activation of T cells in the primary and memory responses of CD8 T cells |
| Q26998750 | The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude |
| Q38083054 | The smallest unit: effector and memory CD8(+) T cell differentiation on the single cell level |
| Q42267787 | The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells |
| Q34865003 | The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection |
| Q37484860 | Thymus transcriptome reveals novel pathways in response to avian pathogenic Escherichia coli infection |
| Q27008423 | To affinity and beyond: harnessing the T cell receptor for cancer immunotherapy |
| Q90401404 | Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis |
| Q34064074 | Transcriptional control of effector and memory CD8+ T cell differentiation |
| Q41636146 | Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation. |
| Q37042924 | Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice |
| Q89486105 | Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells |
| Q36880390 | Type 1 interferon licenses naïve CD8 T cells to mediate anti-viral cytotoxicity |
| Q50535489 | Understanding Subset Diversity in T Cell Memory. |
| Q39889227 | Unexpected positive control of NFκB and miR-155 by DGKα and ζ ensures effector and memory CD8+ T cell differentiation. |
| Q35935892 | Viral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses |
| Q35951949 | Whole transcriptome analysis for T cell receptor-affinity and IRF4-regulated clonal expansion of T cells |
| Q50901203 | With(out) a little help from my friends: an IL-12/CD40L-mediated feed-forward loop between CD8+ T cells and DCs. |
| Q34071196 | c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells |
| Q89540099 | miR-155 Overexpression in OT-1 CD8+ T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen |
| Q28082960 | microRNAs function in CD8+T cell biology |
| Q36607019 | mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function |
| Q37415209 | pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion |
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