Transcription factor Tbx18 induces the differentiation of c-kit canine mesenchymal stem cells (cMSCs) into SAN-like pacemaker cells in a co-culture model in vitro

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Transcription factor Tbx18 induces the differentiation of c-kit canine mesenchymal stem cells (cMSCs) into SAN-like pacemaker cells in a co-culture model in vitro is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID6129520
P698PubMed publication ID30210689

P2093author name stringHua Xiao
Shu Lin
Song Peng
Yong-Jun Yang
Zhi-Yuan Song
Yi-Zhang Lin
P2860cites workIdentification of a gene encoding a hyperpolarization-activated pacemaker channel of brainQ24336296
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Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissuesQ43542437
I(f) current and spontaneous activity in mouse embryonic ventricular myocytesQ43542922
Properties of the hyperpolarization-activated current (I(f)) in isolated mouse sino-atrial cellsQ43737605
Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node.Q46036929
Molecular architecture of the human sinus node: insights into the function of the cardiac pacemakerQ46535702
Model clamp and its application to synchronization of rabbit sinoatrial node cells.Q52292691
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Junctional delay, frequency, and direction-dependent uncoupling of human heterotypic Cx45/Cx43 gap junction channels.Q53692125
Electromagnetic fields and nanomagnetic particles increase the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.Q54312757
Formation of the Venous Pole of the Heart From an Nkx2-5-Negative Precursor Population Requires Tbx18Q56000972
Organisation of the mouse sinoatrial node: structure and expression of HCN channelsQ59594730
Differential Expression of Ion Channel Transcripts in Atrial Muscle and Sinoatrial Node in RabbitQ59594734
[Sino-atrial node transplantation: an experimental study]Q71778003
Differential expression of gap junction proteins in the canine sinus nodeQ74405494
Adult cardiac stem cells are multipotent and support myocardial regenerationQ29620122
Heterotypic gap junction channels as voltage-sensitive valves for intercellular signalingQ30489929
Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiationQ30523741
Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.Q30544927
Funny current downregulation and sinus node dysfunction associated with atrial tachyarrhythmia: a molecular basis for tachycardia-bradycardia syndrome.Q33157216
Differentiation of bone marrow stromal cells into the cardiac phenotype requires intercellular communication with myocytes.Q33208043
Cardiomyocytes can be generated from marrow stromal cells in vitroQ33843659
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T-targets: clues to understanding the functions of T-box proteinsQ34124665
Direct conversion of human fibroblasts to multilineage blood progenitors.Q34148584
A family of hyperpolarization-activated mammalian cation channelsQ34472604
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.Q34580492
Pacemaker current (I(f)) in the human sinoatrial node.Q34682132
Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokinesQ34698821
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Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppressionQ34997952
Hyperpolarization-activated cation currents: from molecules to physiological functionQ35019781
Phospholamban: a crucial regulator of cardiac contractilityQ35167969
The funny current in the context of the coupled-clock pacemaker cell system.Q35705710
HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in miceQ36116647
Pathophysiology of HCN channelsQ36840738
Implantation of sinoatrial node cells into canine right ventricle: biological pacing appears limited by the substrateQ36954373
Shox2 influences mesenchymal stem cell fate in a co-culture model in vitroQ37032381
Calmodulin kinase II is required for fight or flight sinoatrial node physiologyQ37153688
The cardiac pacemaker currentQ37547401
Development of the pacemaker tissues of the heart.Q37687712
Stem cell-based biological pacemakers from proof of principle to therapy: a reviewQ38212017
Targeting pleiotropic signaling pathways to control adult cardiac stem cell fate and function.Q38234910
In situ investigation of allografted mouse HCN4 gene-transfected rat bone marrow mesenchymal stromal cells with the use of patch-clamp recording of ventricular slicesQ38548248
Canine bone marrow mesenchymal stromal cells with lentiviral mHCN4 gene transfer create cardiac pacemakersQ38549177
Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial nodeQ38553626
Electric-Pulse Current Stimulation Increases If Current in mShox2 Genetically Modified Canine Mesenchymal Stem CellsQ41183899
Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cellsQ41665390
Reprogramming paces the heartQ42082753
High basal protein kinase A-dependent phosphorylation drives rhythmic internal Ca2+ store oscillations and spontaneous beating of cardiac pacemaker cellsQ42489642
HCN2 overexpression in newborn and adult ventricular myocytes: distinct effects on gating and excitabilityQ42506846
Coupling an HCN2-expressing cell to a myocyte creates a two-cell pacing unitQ43279831
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectmesenchymal stem cellQ1922379
P304page(s)2511-2528
P577publication date2018-01-01
P1433published inAmerican Journal of Translational ResearchQ4744272
P1476titleTranscription factor Tbx18 induces the differentiation of c-kit canine mesenchymal stem cells (cMSCs) into SAN-like pacemaker cells in a co-culture model in vitro
P478volume10

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cites work (P2860)
Q64054916Congenital Disorders of the Human Urinary Tract: Recent Insights From Genetic and Molecular Studies
Q91790358Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker

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