scholarly article | Q13442814 |
P356 | DOI | 10.1002/GCC.22245 |
P698 | PubMed publication ID | 25727050 |
P50 | author | Kajsa Paulsson | Q43156682 |
P2093 | author name string | Bertil Johansson | |
Mikael Behrendtz | |||
Anders Castor | |||
Linda Olsson | |||
Andrea Biloglav | |||
Ferras Albitar | |||
P2860 | cites work | Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia | Q43221788 |
An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions. | Q43922213 | ||
Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor | Q44519043 | ||
IKZF1 and CRLF2 gene alterations correlate with poor prognosis in Japanese BCR-ABL1-negative high-risk B-cell precursor acute lymphoblastic leukemia. | Q45326639 | ||
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome | Q46355702 | ||
A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia. | Q46677100 | ||
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations. | Q46933149 | ||
FLT3 mutations in a 10 year consecutive series of 177 childhood acute leukemias and their impact on global gene expression patterns | Q46944335 | ||
Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011. | Q50860875 | ||
ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia. | Q52882383 | ||
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. | Q53307880 | ||
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros | Q57734316 | ||
Impact of IKZF1 deletions and PAX5 amplifications in pediatric B-cell precursor ALL treated according to NOPHO protocols | Q58861726 | ||
A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma | Q71806450 | ||
Location and function of linker histones | Q77659483 | ||
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study | Q24651897 | ||
Fast and accurate short read alignment with Burrows-Wheeler transform | Q24653853 | ||
IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report | Q27851487 | ||
IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL. | Q27851563 | ||
Tyrosine kinase inhibitor therapy induces remission in a patient with refractory EBF1-PDGFRB-positive acute lymphoblastic leukemia. | Q27852421 | ||
Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment | Q28202932 | ||
The Ikaros gene is required for the development of all lymphoid lineages | Q28594316 | ||
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia | Q29614324 | ||
Control of lymphocyte development by the Ikaros gene family | Q33632444 | ||
Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles | Q33938184 | ||
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia | Q34314927 | ||
Biology, risk stratification, and therapy of pediatric acute leukemias: an update | Q34764504 | ||
Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes. | Q35741581 | ||
Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome | Q35876592 | ||
Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study | Q35885293 | ||
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia | Q36174146 | ||
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project | Q36542815 | ||
IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol | Q36862420 | ||
Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia. | Q36862511 | ||
What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia? | Q37060647 | ||
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia | Q37172988 | ||
Genetic loss of SH2B3 in acute lymphoblastic leukemia | Q37215146 | ||
JAK mutations in high-risk childhood acute lymphoblastic leukemia | Q37224111 | ||
Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL. | Q37226741 | ||
IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan | Q39730823 | ||
Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia | Q39814053 | ||
Ikaros isoform x is selectively expressed in myeloid differentiation. | Q40665471 | ||
Infrequent occurrence of mutations in the PH domain of LNK in patients with JAK2 mutation-negative 'idiopathic' erythrocytosis | Q42583762 | ||
P433 | issue | 5 | |
P921 | main subject | mutation | Q42918 |
lymphoblastic leukemia | Q18553852 | ||
P304 | page(s) | 315-325 | |
P577 | publication date | 2015-02-26 | |
P1433 | published in | Genes, Chromosomes and Cancer | Q5532697 |
P1476 | title | Cooperative genetic changes in pediatric B-cell precursor acute lymphoblastic leukemia with deletions or mutations of IKZF1 | |
P478 | volume | 54 |
Q91910029 | An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia |
Q38974705 | Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). |
Q35679720 | Expression of Ik6 and Ik8 Isoforms and Their Association with Relapse and Death in Mexican Children with Acute Lymphoblastic Leukemia |
Q41000106 | Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia |
Q91843913 | IKZF1 deletions in pediatric acute lymphoblastic leukemia: still a poor prognostic marker? |
Q36980511 | Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia |
Q41556401 | Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study. |
Q91997647 | SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain |
Q41617996 | Selected miRNA levels are associated with IKZF1 microdeletions in pediatric acute lymphoblastic leukemia. |
Q64965821 | Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases. |