Calcitriol and cancer therapy: A missed opportunity

Calcitriol and cancer therapy: A missed opportunity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BONR.2018.06.002
P953full work available at URLhttps://linkinghub.elsevier.com/retrieve/pii/S2352187218300354
P932PMC publication ID6303233
P698PubMed publication ID30591928

P2093author name stringDonald L Trump
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Androgen enhances the antiproliferative activity of vitamin D3 by suppressing 24-hydroxylase expression in LNCaP cellsQ40307503
Investigation of the mechanisms by which EB1089 abrogates apoptosis induced by 9-cis retinoic acid in pancreatic cancer cellsQ40341429
Genistein potentiates the growth inhibitory effects of 1,25-dihydroxyvitamin D3 in DU145 human prostate cancer cells: role of the direct inhibition of CYP24 enzyme activityQ40410049
Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogensQ40470534
Pre-diagnostic vitamin D concentrations and cancer risks in older individuals: an analysis of cohorts participating in the CHANCES consortiumQ40937152
Novel 20-epi-vitamin D3 analog combined with 9-cis-retinoic acid markedly inhibits colony growth of prostate cancer cellsQ40943398
Liarozole acts synergistically with 1alpha,25-dihydroxyvitamin D3 to inhibit growth of DU 145 human prostate cancer cells by blocking 24-hydroxylase activityQ40958308
Modulation of cell growth, differentiation, and production of interleukin-3 by 1 alpha,25-dihydroxyvitamin D3 in the murine myelomonocytic leukemia cell line WEHI-3.Q41344708
1α,25-Dihydroxycholecalciferol and a human myeloid leukaemia cell line (HL-60)Q41554261
Whole-cell uptake and nuclear localization of 1,25-dihydroxycholecalciferol by breast cancer cells (T47 D) in cultureQ41609946
20-EPI-vitamin D3 analogues: A novel class of potent regulators of cell growth and immune responsesQ41664866
Effect of 1 alpha-hydroxyvitamin D3 on metastasis of rat ascites hepatoma K-231.Q41906213
Actions of vitamin D3, analogs on human prostate cancer cell lines: comparison with 1,25-dihydroxyvitamin D3.Q42275515
Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma.Q42514552
Action of 1,25(OH)2D3 on the cell cycle genes, cyclin D1, p21 and p27 in MCF-7 cellsQ42538869
Differential effects of 1,25-dihydroxyvitamin D3 and tetradecanoylphorbol acetate on cell cycle and apoptosis of MCF-7 cells and a vitamin D3-resistant variantQ42546942
1 alpha, 25-dihydroxyvitamin D3 (calcitriol) induces apoptosis in stimulated T cells through an IL-2 dependent mechanismQ42555132
Treatment of early recurrent prostate cancer with 1,25-dihydroxyvitamin D3 (calcitriol)Q42677963
Phase I safety and pharmacodynamic of inecalcitol, a novel VDR agonist with docetaxel in metastatic castration-resistant prostate cancer patientsQ42704868
1 alpha,25-Dihydroxyvitamin D3 markedly enhances chemically-induced transformation in BALB 3T3 cellsQ42820638
Specific binding of 1,25-dihydroxycholecalciferol in human medullary thyroid carcinomaQ42875228
Phase 2 trial of weekly intravenous 1,25 dihydroxy cholecalciferol (calcitriol) in combination with dexamethasone for castration-resistant prostate cancerQ43158086
A phase II trial of calcitriol and naproxen in recurrent prostate cancer.Q43295148
Two novel 14-Epi-analogues of 1,25-dihydroxyvitamin D3 inhibit the growth of human breast cancer cells in vitro and in vivoQ43503491
Vitamin D(3)-induced apoptosis of murine squamous cell carcinoma cells. Selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1.Q43594118
A Phase I trial of pulse calcitriol in patients with refractory malignancies: pulse dosing permits substantial dose escalationQ43645557
Low plasma 25-hydroxyvitamin D and risk of tobacco-related cancerQ43776473
Phase II study of 1alpha-hydroxyvitamin D(2) in the treatment of advanced androgen-independent prostate cancerQ43802386
Combination of 1alpha,25-dihydroxyvitamin D(3) with dexamethasone enhances cell cycle arrest and apoptosis: role of nuclear receptor cross-talk and Erk/Akt signaling.Q43829476
Preclinical activity of ketoconazole in combination with calcitriol or the vitamin D analogue EB 1089 in prostate cancer cellsQ44156944
Pharmacokinetics of high-dose oral calcitriol: results from a phase 1 trial of calcitriol and paclitaxelQ44259177
P407language of work or nameEnglishQ1860
P921main subjectcalcitriolQ139195
P304page(s)110-119
P577publication date2018-12-01
P1433published inBone reportsQ27726039
P1476titleCalcitriol and cancer therapy: A missed opportunity
P478volume9

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