| P2093 | author name string | Ingo Schmitz | |
| | Burkhart Schraven | |
| | Thomas Fischer | |
| | Ursula Bommhardt | |
| | Clemens Cammann | |
| | Tanima Bose | |
| | Florian H Heidel | |
| | Tina Schnöder | |
| | Theresa Lowinus | |
| | Ulrike Seifert | |
| | Subbaiah Chary Nimmagadda | |
| P2860 | cites work | Expression and chromosomal localization of a lymphocyte K+ channel gene | Q24315122 |
| | Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes | Q24652512 |
| | Voltage-Gated Potassium Channels Kv1.3--Potentially New Molecular Target in Cancer Diagnostics and Therapy | Q26783062 |
| | Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling | Q27860529 |
| | The phosphoinositide 3-kinase pathway and therapy resistance in cancer | Q28082811 |
| | Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences | Q28144704 |
| | A novel potassium channel in lymphocyte mitochondria | Q28301096 |
| | Drug combination studies and their synergy quantification using the Chou-Talalay method | Q29617422 |
| | Pharmacodynamics of memantine: an update | Q30490604 |
| | Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis. | Q32061441 |
| | A new quantitative assay for cytochrome c release in apoptotic cells. | Q34207175 |
| | A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia | Q34315750 |
| | Targeting the MYC and PI3K pathways eliminates leukemia-initiating cells in T-cell acute lymphoblastic leukemia | Q34645214 |
| | Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies | Q35669226 |
| | The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL | Q35850028 |
| | Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells | Q36206219 |
| | Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells | Q36402419 |
| | Ion channels in innate and adaptive immunity | Q36769825 |
| | Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. | Q37109225 |
| | Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade. | Q53071978 |
| | HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors. | Q53866705 |
| | Biophysical characterization and expression analysis of Kv1.3 potassium channel in primary human leukemic B cells. | Q54245001 |
| | Differential Activity of Voltage- and Ca2+-Dependent Potassium Channels in Leukemic T Cell Lines: Jurkat Cells Represent an Exceptional Case. | Q55057818 |
| | PI3K/AKT/mTORC1 and MEK/ERK signaling in T-cell acute lymphoblastic leukemia: new options for targeted therapy | Q56983019 |
| | The ion channel network in T lymphocytes, a target for immunotherapy | Q83092219 |
| | High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia | Q37268926 |
| | Myc's broad reach | Q37299032 |
| | Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia | Q37331742 |
| | Voltage-gated potassium channels as therapeutic targets | Q37464784 |
| | Ionic immune suppression within the tumour microenvironment limits T cell effector function. | Q37548587 |
| | Kv1.3 Channels Mark Functionally Competent CD8+ Tumor-Infiltrating Lymphocytes in Head and Neck Cancer. | Q37559965 |
| | Ion channels and anti-cancer immunity. | Q37566472 |
| | The functional network of ion channels in T lymphocytes | Q37597609 |
| | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. | Q37865381 |
| | Targeting the voltage-dependent K(+) channels Kv1.3 and Kv1.5 as tumor biomarkers for cancer detection and prevention. | Q37971950 |
| | Targeting ion channels in leukemias: a new challenge for treatment | Q37971953 |
| | Treatment decisions for elderly patients with haematological malignancies: a dilemma | Q38030767 |
| | How I treat the older patient with acute myeloid leukemia | Q38291150 |
| | Outlook on PI3K/AKT/mTOR inhibition in acute leukemia | Q38521775 |
| | Pharmacological targeting of ion channels for cancer therapy: In vivo evidences | Q38666902 |
| | Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles. | Q38973733 |
| | Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines | Q39148272 |
| | Classics in Chemical Neuroscience: Memantine | Q39454363 |
| | Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness | Q39555393 |
| | Immunosuppression by N-methyl-D-aspartate receptor antagonists is mediated through inhibition of Kv1.3 and KCa3.1 channels in T cells | Q39685182 |
| | A phase I study of the mammalian target of rapamycin inhibitor sirolimus and MEC chemotherapy in relapsed and refractory acute myelogenous leukemia. | Q39937037 |
| | Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization | Q40213057 |
| | Epo-induced erythroid maturation is dependent on Plcγ1 signaling. | Q40386692 |
| | c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations. | Q40406189 |
| | Regulation of c-myc expression by Ras/Raf signalling | Q41065368 |
| | NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells | Q41616016 |
| | Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells | Q42254718 |
| | Therapeutic targeting of c-Myc in T-cell acute lymphoblastic leukemia, T-ALL | Q42705204 |
| | Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia | Q42742064 |
| | The interaction index: a measure of drug synergism | Q44050835 |
| | Daunorubicin- and Ara-C-induced interphasic apoptosis of human type II leukemia cells is caspase-8-independent | Q44183911 |
| | Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia. | Q44188484 |
| | PI3K/mTOR inhibition upregulates NOTCH-MYC signalling leading to an impaired cytotoxic response | Q45038180 |
| | A phase Ib GOELAMS study of the mTOR inhibitor RAD001 in association with chemotherapy for AML patients in first relapse. | Q45731131 |
| | Inhibition of MEK signaling enhances the ability of cytarabine to induce growth arrest and apoptosis of acute myelogenous leukemia cells. | Q45957588 |
| | Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo | Q46385716 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | leukemia | Q29496 |
| | acute leukemia | Q976388 |
| P304 | page(s) | 5 | |
| P577 | publication date | 2019-01-16 | |
| P1433 | published in | Cell Communication and Signaling | Q1254390 |
| P1476 | title | Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of K1.3 potassium channels, AKT and ERK1/2 signaling | |
| P478 | volume | 17 | |