| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.275.5305.1481 |
| P698 | PubMed publication ID | 9045614 |
| P50 | author | Eric Verdin | Q37373521 |
| Melanie Ott | Q42321952 | ||
| Savita Pahwa | Q69459018 | ||
| P2093 | author name string | S Emiliani | |
| C Van Lint | |||
| N Chirmule | |||
| J Lovett | |||
| G Herbein | |||
| T McCloskey | |||
| P433 | issue | 5305 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1481-1485 | |
| P577 | publication date | 1997-03-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway | |
| P478 | volume | 275 |
| Q35169682 | "Translocatory proteins" and "protein transduction domains": a critical analysis of their biological effects and the underlying mechanisms |
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| Q45883791 | A two-component expression system that responds to inflammatory stimuli in vivo |
| Q63351469 | Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity |
| Q31793569 | Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines |
| Q41961224 | An AP-1 binding site in the enhancer/core element of the HIV-1 promoter controls the ability of HIV-1 to establish latent infection |
| Q33916162 | An attenuated herpes simplex virus type 1 (HSV1) encoding the HIV-1 Tat protein protects mice from a deadly mucosal HSV1 challenge |
| Q36315550 | Analysis of the interaction of primate retroviruses with the human RNA interference machinery |
| Q92906228 | Anti-Tat Immunity in HIV-1 Infection: Effects of Naturally Occurring and Vaccine-Induced Antibodies Against Tat on the Course of the Disease |
| Q33836069 | Antiapoptotic function of Cdk9 (TAK/P-TEFb) in U937 promonocytic cells |
| Q73138904 | Antibodies to Tat and Vpr in the GRIV cohort: differential association with maintenance of long-term non-progression status in HIV-1 infection |
| Q33888584 | Astrocyte elevated gene-1 is a novel modulator of HIV-1-associated neuroinflammation via regulation of nuclear factor-κB signaling and excitatory amino acid transporter-2 repression |
| Q39579254 | B-lymphocyte proliferation during bovine leukemia virus-induced persistent lymphocytosis is enhanced by T-lymphocyte-derived interleukin-2. |
| Q43907092 | C3-Tat/HIV-regulated intraarticular human interleukin-1 receptor antagonist gene therapy results in efficient inhibition of collagen-induced arthritis superior to cytomegalovirus-regulated expression of the same transgene |
| Q41818257 | Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies |
| Q64259098 | Continued Decay of HIV Proviral DNA Upon Vaccination With HIV-1 Tat of Subjects on Long-Term ART: An 8-Year Follow-Up Study |
| Q24550678 | Contribution of immune activation to the pathogenesis and transmission of human immunodeficiency virus type 1 infection |
| Q39582630 | Costimulatory pathways in lymphocyte proliferation induced by the simian immunodeficiency virus SIVsmmPBj14. |
| Q33730729 | Decreased ability of HIV-1 tat protein-treated accessory cells to organize cellular clusters is associated with partial activation of T cells |
| Q33641854 | Differential effects of human immunodeficiency virus isolates on beta-chemokine and gamma interferon production and on cell proliferation. |
| Q40686654 | Differentially expressed genes in HIV-1 tat-expressing CD4(+) T-cell line |
| Q33860989 | Displacement of SATB1-bound histone deacetylase 1 corepressor by the human immunodeficiency virus type 1 transactivator induces expression of interleukin-2 and its receptor in T cells. |
| Q36524970 | Early transcription from nonintegrated DNA in human immunodeficiency virus infection |
| Q42061242 | Effects of different routes of administration on the immunogenicity of the Tat protein and a Tat-derived peptide |
| Q34342523 | Evaluation of Tat-encoding bicistronic human immunodeficiency virus type 1 gene transfer vectors in primary canine bone marrow mononuclear cells. |
| Q39025427 | Evidence for the HIV-1 phenotype switch as a causal factor in acquired immunodeficiency. |
| Q36171859 | Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1. |
| Q34033148 | From the outside in: extracellular activities of HIV Tat. |
| Q92135927 | Genetic variation and function of the HIV-1 Tat protein |
| Q51961814 | HIV Nef increases T cell ERK MAP kinase activity. |
| Q30245486 | HIV, Aging, and Viral Coinfections: Taking the Long View. |
| Q36418014 | HIV-1 Nef increases T cell activation in a stimulus-dependent manner |
| Q24564896 | HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses |
| Q35552889 | HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial |
| Q36109585 | HIV-1 Tat protein vaccination in mice infected with Mycobacterium tuberculosis is safe, immunogenic and reduces bacterial lung pathology |
| Q24543241 | HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim. |
| Q42097093 | HIV-1 Tat-mediated induction of CCL5 in astrocytes involves NF-κB, AP-1, C/EBPα and C/EBPγ transcription factors and JAK, PI3K/Akt and p38 MAPK signaling pathways |
| Q21245215 | HIV-1 gene expression: lessons from provirus and non-integrated DNA |
| Q36986644 | HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4(+) T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial |
| Q36412589 | HIV-Tat regulates macrophage gene expression in the context of neuroAIDS. |
| Q33825196 | Human anti-HIV-1 tat sFv intrabodies for gene therapy of advanced HIV-1-infection and AIDS. |
| Q40004324 | Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation |
| Q40084244 | Inhibition of HIV-1 replication with designed miRNAs expressed from RNA polymerase II promoters |
| Q39880793 | Inhibition of human immunodeficiency virus type 1 replication in vitro by a novel combination of anti-Tat single-chain intrabodies and NF-kappa B antagonists |
| Q36011366 | Interferon alpha and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS. |
| Q92340177 | Kinetics of Early Innate Immune Activation during HIV-1 Infection of Humanized Mice |
| Q73807445 | Macrophages and T-cell apoptosis in HIV infection: a leading role for accessory cells? |
| Q39834242 | Mechanism for HIV-1 Tat insertion into the endosome membrane |
| Q36394982 | Midkine, a cytokine that inhibits HIV infection by binding to the cell surface expressed nucleolin |
| Q33889326 | Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon |
| Q39577894 | Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef |
| Q36767508 | Modulation of the immunological synapse: a key to HIV-1 pathogenesis? |
| Q90635021 | Morphine exposure exacerbates HIV-1 Tat driven changes to neuroinflammatory factors in cultured astrocytes |
| Q28246872 | Multiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infection |
| Q34070377 | Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line |
| Q35111008 | NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta |
| Q33808225 | Novel Tat-encoding bicistronic human immunodeficiency virus type 1-based gene transfer vectors for high-level transgene expression |
| Q39135199 | Overexpression of PRMT6 does not suppress HIV-1 Tat transactivation in cells naturally lacking PRMT6. |
| Q24684750 | Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication |
| Q33783635 | Priming with tat-deleted caprine arthritis encephalitis virus (CAEV) proviral DNA or live virus protects goats from challenge with pathogenic CAEV. |
| Q33958031 | Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1. |
| Q36489392 | Reciprocal transactivation between HIV-1 and other human viruses |
| Q33865436 | Role for human immunodeficiency virus type 1 Tat protein in suppression of viral reverse transcriptase activity during late stages of viral replication |
| Q34158436 | Role of uncontrolled HIV RNA level and immunodeficiency in the occurrence of malignancy in HIV-infected patients during the combination antiretroviral therapy era: Agence Nationale de Recherche sur le Sida (ANRS) CO3 Aquitaine Cohort |
| Q24797263 | SIRT1 regulates HIV transcription via Tat deacetylation |
| Q40273841 | Sequence variation within the dominant amino terminus epitope affects antibody binding and neutralization of human immunodeficiency virus type 1 Tat protein |
| Q36498220 | Single-cell, phosphoepitope-specific analysis demonstrates cell type- and pathway-specific dysregulation of Jak/STAT and MAPK signaling associated with in vivo human immunodeficiency virus type 1 infection |
| Q40129583 | Sp1 and Sp3 regulate basal transcription of the human APOBEC3G gene |
| Q42030593 | Specific ligation to double-stranded RNA for analysis of cellular RNA::RNA interactions |
| Q40743714 | Stability of HIV-1 subtype B and C Tat is associated with variation in the carboxyl-terminal region |
| Q39561905 | Superantigen activation of CD4+ and CD8+T cells from HIV-infected subjects: role of costimulatory molecules and antigen-presenting cells (APC) |
| Q35350405 | Suppression of Foxo1 activity and down-modulation of CD62L (L-selectin) in HIV-1 infected resting CD4 T cells |
| Q42273481 | T-Cell Signaling in HIV-1 Infection |
| Q28214887 | Tat acetyl-acceptor lysines are important for human immunodeficiency virus type-1 replication |
| Q33785321 | Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains |
| Q24683211 | Tat protein induces self-perpetuating permissivity for productive HIV-1 infection |
| Q24524076 | Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway |
| Q33883575 | The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication |
| Q22248066 | The C Terminus of HIV-1 Tat Modulates the Extent of CD178-mediated Apoptosis of T Cells |
| Q22248069 | The Glutamine-rich Region of the HIV-1 Tat Protein Is Involved in T-cell Apoptosis |
| Q35040673 | The HIV-1 Tat protein induces the activation of CD8+ T cells and affects in vivo the magnitude and kinetics of antiviral responses |
| Q41975845 | The co-receptor signaling model of HIV-1 pathogenesis in peripheral CD4 T cells |
| Q26823236 | The macrophage: a therapeutic target in HIV-1 infection |
| Q36685165 | The presence of HIV-1 Tat protein second exon delays fas protein-mediated apoptosis in CD4+ T lymphocytes: a potential mechanism for persistent viral production |
| Q33864926 | The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4+ T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study |
| Q54217910 | The role of HIV Tat protein in HIV-related cardiovascular diseases. |
| Q40872007 | The role of chromatin in HIV-1 transcriptional regulation |
| Q40903444 | The second chance story of HIV-1 DNA: Unintegrated? Not a problem! |
| Q28361880 | The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation |
| Q28476094 | Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subjects on HAART |
| Q35890307 | Transcription factor binding sites downstream of the human immunodeficiency virus type 1 transcription start site are important for virus infectivity. |
| Q24815940 | Transcription factor binding sites in the pol gene intragenic regulatory region of HIV-1 are important for virus infectivity |
| Q35155025 | Transcriptional profiles of latent human immunodeficiency virus in infected individuals: effects of Tat on the host and reservoir |
| Q36540182 | Viral modulation of T-cell receptor signaling |
| Q40623679 | Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection |
| Q34040248 | Virulence and pathogenesis of HIV-1 infection: an evolutionary perspective |
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