scholarly article | Q13442814 |
P2093 | author name string | Ivet Bahar | |
Bing Liu | |||
Hongchun Li | |||
Fen Pei | |||
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Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology. | Q47564614 | ||
Rapamycin prevents drug seeking via disrupting reconsolidation of reward memory in rats | Q47963921 | ||
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Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice | Q24650110 | ||
Norepinephrine and stimulant addiction | Q24656833 | ||
Neurobiologic Advances from the Brain Disease Model of Addiction | Q26774129 | ||
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The neurology of mTOR | Q26824286 | ||
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Ketamine and its preservative, benzethonium chloride, both inhibit human recombinant alpha7 and alpha4beta2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes | Q28199192 | ||
The neurocircuitry of illicit psychostimulant addiction: acute and chronic effects in humans | Q28236333 | ||
Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling | Q28253698 | ||
Dopaminergic neurons inhibit striatal output through non-canonical release of GABA | Q28276335 | ||
Striatal signal transduction and drug addiction | Q28392093 | ||
Genes and (common) pathways underlying drug addiction | Q28471939 | ||
Involvement of mitogen-stimulated p70-S6 kinase in the development of sensitization to the methamphetamine-induced rewarding effect in rats | Q28575201 | ||
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion | Q29547251 | ||
Molecular mechanisms of mTOR-mediated translational control | Q29615529 | ||
Drug addiction, dysregulation of reward, and allostasis | Q29616741 | ||
Proteomics. Tissue-based map of the human proteome | Q29617248 | ||
STITCH 5: augmenting protein–chemical interaction networks with tissue and affinity data | Q30002336 | ||
The 1,4-benzodiazepine Ro5-4864 (4-chlorodiazepam) suppresses multiple pro-inflammatory mast cell effector functions | Q30537652 | ||
The development and maintenance of drug addiction | Q30560436 | ||
The addicted human brain: insights from imaging studies | Q30794301 | ||
The role of the endogenous cannabinoid system in drug addiction | Q33344540 | ||
Gap junction blockers: a potential approach to attenuate morphine withdrawal symptoms | Q33586541 | ||
mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels. | Q33620587 | ||
Cocaine self-administration in dopamine-transporter knockout mice | Q33858028 | ||
The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. | Q33940362 | ||
Cocaine modulates mammalian circadian clock timing by decreasing serotonin transport in the SCN. | Q34006034 | ||
Serotonin Receptors – From Molecular Biology to Clinical Applications | Q34143560 | ||
NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia | Q34149624 | ||
Addiction and the brain: the role of neurotransmitters in the cause and treatment of drug dependence. | Q34200260 | ||
Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders | Q34358701 | ||
Synaptic plasticity and drug addiction | Q34386424 | ||
Cocaine-induced expression changes of axon guidance molecules in the adult rat brain | Q34390929 | ||
Neurobiology of addiction: a neurocircuitry analysis | Q34535855 | ||
Ketamine, but not phencyclidine, selectively modulates cerebellar GABA(A) receptors containing alpha6 and delta subunits | Q34656312 | ||
The role of acetylcholine in cocaine addiction. | Q34700186 | ||
Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity | Q34762533 | ||
Methylphenidate and μ opioid receptor interactions: a pharmacological target for prevention of stimulant abuse. | Q35016913 | ||
Chemogenomics knowledgebased polypharmacology analyses of drug abuse related G-protein coupled receptors and their ligands. | Q35102561 | ||
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New medications for drug addiction hiding in glutamatergic neuroplasticity | Q35333393 | ||
AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors. | Q35587067 | ||
Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria | Q35617941 | ||
An emerging role for the Mammalian target of rapamycin in "pathological" protein translation: relevance to cocaine addiction | Q35738367 | ||
Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves | Q35874165 | ||
Function of opioids in the enteric nervous system | Q35882827 | ||
Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis. | Q35985429 | ||
Cocaine-mediated microglial activation involves the ER stress-autophagy axis. | Q36111649 | ||
Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization | Q36406346 | ||
Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy. | Q36444154 | ||
Molecular mechanisms of opioid receptor-dependent signaling and behavior | Q36974487 | ||
A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine. | Q37029832 | ||
Spine dynamics and synapse remodeling during LTP and memory processes. | Q37131133 | ||
Role of IGF1R(+) MSCs in modulating neuroplasticity via CXCR4 cross-interaction | Q37227786 | ||
Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence. | Q37372800 | ||
Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathways | Q37380130 | ||
KEGG: new perspectives on genomes, pathways, diseases and drugs | Q37556832 | ||
Molecular Mechanism: ERK Signaling, Drug Addiction, and Behavioral Effects. | Q37671995 | ||
Methamphetamine induces autophagy as a pro-survival response against apoptotic endothelial cell death through the Kappa opioid receptor | Q37680254 | ||
The endocannabinoid system and the brain | Q38026949 | ||
Emerging roles of actin cytoskeleton regulating enzymes in drug addiction: actin or reactin'? | Q38083388 | ||
mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse | Q38199194 | ||
Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling. | Q38267155 | ||
Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA. | Q38332823 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P921 | main subject | pleiotropy | Q1134884 |
P577 | publication date | 2019-03-08 | |
P1433 | published in | Frontiers in Pharmacology | Q2681208 |
P1476 | title | Quantitative Systems Pharmacological Analysis of Drugs of Abuse Reveals the Pleiotropy of Their Targets and the Effector Role of mTORC1 | |
P478 | volume | 10 |
Q92643628 | Domain-mediated interactions for protein subfamily identification |
Q92763088 | Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology |
Q90715435 | QuartataWeb: integrated chemical-protein-pathway mapping for polypharmacology and chemogenomics |
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