| P50 | author | Pavel Mazin | Q58335646 |
| | Alexey Morozov | Q61103806 |
| | Mikhail Yevgenyev | Q88673480 |
| | Aleksey Ustyugov | Q38545717 |
| P2093 | author name string | Andrey V Maltsev | |
| | Ekaterina A Vikhareva | |
| | Alexander P Rezvykh | |
| | Maria M Chicheva | |
| | Sergei Y Funikov | |
| P2860 | cites work | Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice | Q48645659 |
| | Effect of apigenin, kaempferol and resveratrol on the gene expression and protein secretion of tumor necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) in RAW-264.7 macrophages. | Q50521335 |
| | Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in Alzheimer's disease. | Q50646415 |
| | CD84 mediates CLL-microenvironment interactions. | Q51620105 |
| | Rodent models of amyotrophic lateral sclerosis. | Q51822707 |
| | Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death. | Q52537887 |
| | Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia: clinical and molecular findings in three families supporting genetic heterogeneity in Smith-McCort dysplasia. | Q52934754 |
| | Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. | Q53358479 |
| | Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. | Q55356425 |
| | Amyotrophic lateral sclerosis | Q56531747 |
| | Activation-dependent modulation of B lymphocyte migration to chemokines | Q74247915 |
| | Upregulation of GSK3beta expression in frontal and temporal cortex in ALS with cognitive impairment (ALSci) | Q80552720 |
| | Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis | Q80838012 |
| | Monitoring systemic oxidative stress in an animal model of amyotrophic lateral sclerosis | Q82607328 |
| | Decreased expression of Bmal2 in patients with Parkinson's disease | Q84318196 |
| | Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia | Q24600027 |
| | Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease | Q24628685 |
| | Exome sequencing reveals VCP mutations as a cause of familial ALS | Q24631513 |
| | A new subtype of frontotemporal lobar degeneration with FUS pathology | Q24647697 |
| | Misfolded proteins partition between two distinct quality control compartments | Q24651093 |
| | Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis | Q26749169 |
| | A comprehensive review of amyotrophic lateral sclerosis | Q26775401 |
| | Amyotrophic Lateral Sclerosis: New Perpectives and Update | Q26781051 |
| | State of play in amyotrophic lateral sclerosis genetics | Q26864816 |
| | RNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouse | Q27321207 |
| | FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration | Q27342067 |
| | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources | Q27860739 |
| | edgeR: a Bioconductor package for differential expression analysis of digital gene expression data | Q27860819 |
| | Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 | Q28236805 |
| | B-cell receptor signalling and its crosstalk with other pathways in normal and malignant cells | Q28245018 |
| | TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis | Q28270779 |
| | The role of CD80/CD86 in generation and maintenance of functional virus-specific CD8+ T cells in mice infected with lymphocytic choriomeningitis virus | Q28286961 |
| | SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond | Q28298645 |
| | Trimmomatic: a flexible trimmer for Illumina sequence data | Q29547278 |
| | HTSeq--a Python framework to work with high-throughput sequencing data | Q29614489 |
| | Mutations of optineurin in amyotrophic lateral sclerosis | Q29614836 |
| | STAR: ultrafast universal RNA-seq aligner | Q29615052 |
| | Pathogenic superoxide dismutase structure, folding, aggregation and turnover | Q30159887 |
| | Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis | Q30494776 |
| | Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm | Q30559680 |
| | Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions | Q30661910 |
| | Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons | Q33282966 |
| | Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS. | Q33294971 |
| | Modelling amyotrophic lateral sclerosis: progress and possibilities | Q33746289 |
| | Gene ontology analysis for RNA-seq: accounting for selection bias | Q33861598 |
| | Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication | Q33934943 |
| | Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease | Q33999537 |
| | Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS. | Q34019767 |
| | FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis | Q34118590 |
| | Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms. | Q34155410 |
| | Siglec-mediated regulation of immune cell function in disease. | Q34314957 |
| | LINGO-1 receptor promotes neuronal apoptosis by inhibiting WNK3 kinase activity | Q34332453 |
| | Male sterility and enhanced radiation sensitivity in TLS(-/-) mice | Q34662602 |
| | A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model | Q34746889 |
| | Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. | Q34982074 |
| | ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism | Q35605176 |
| | PPLine: An Automated Pipeline for SNP, SAP, and Splice Variant Detection in the Context of Proteogenomics | Q35683877 |
| | Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin | Q35824582 |
| | Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS | Q35887683 |
| | Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS. | Q35906462 |
| | ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease | Q36028454 |
| | Meningeal Infiltration of the Spinal Cord by Non-Classically Activated B Cells is Associated with Chronic Disease Course in a Spontaneous B Cell-Dependent Model of CNS Autoimmune Disease | Q36097332 |
| | Compartmentalization of superoxide dismutase 1 (SOD1G93A) aggregates determines their toxicity | Q36300695 |
| | Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS | Q36310409 |
| | TDP-43 and FUS en route from the nucleus to the cytoplasm | Q36336278 |
| | Transgenic mouse models of amyotrophic lateral sclerosis | Q36468459 |
| | ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function | Q36548825 |
| | Expression of human FUS protein in Drosophila leads to progressive neurodegeneration | Q36584516 |
| | Widespread splicing changes in human brain development and aging | Q36587200 |
| | Histone deacetylase inhibitors: a novel therapeutic approach to Huntington's disease (complex mechanism of neuronal death). | Q36611816 |
| | Intricate interplay between astrocytes and motor neurons in ALS. | Q36637458 |
| | Zbtb20 promotes astrocytogenesis during neocortical development | Q36719166 |
| | Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss | Q36906420 |
| | Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis | Q36967649 |
| | Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis | Q37079670 |
| | Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice | Q37132099 |
| | Genetics of amyotrophic lateral sclerosis: an update. | Q37153922 |
| | IL-6 and metabolism-new evidence and new questions | Q37155563 |
| | Loss of ZBTB20 impairs circadian output and leads to unimodal behavioral rhythms | Q37276766 |
| | CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions | Q37548642 |
| | A plural role for lipids in motor neuron diseases: energy, signaling and structure | Q37594297 |
| | ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects | Q37609639 |
| | Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice | Q37659809 |
| | Protein misfolding in neurodegenerative diseases: implications and strategies | Q37697832 |
| | Siglec functions of microglia | Q38212200 |
| | Lymphocytes and autoimmunity after spinal cord injury | Q38228964 |
| | The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration. | Q38244879 |
| | Microglial activation as a compelling target for treating acute traumatic brain injury. | Q38267047 |
| | Microglia Responses in Acute and Chronic Neurological Diseases: What Microglia-Specific Transcriptomic Studies Taught (and did Not Teach) Us. | Q38430287 |
| | Inference on periodicity of circadian time series | Q38780354 |
| | Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology | Q39088915 |
| | Microbiota, Immune Subversion, and Chronic Inflammation | Q39203697 |
| | A highly conserved program of neuronal microexons is misregulated in autistic brains | Q39403790 |
| | IL-10 Controls Early Microglial Phenotypes and Disease Onset in ALS Caused by Misfolded Superoxide Dismutase 1. | Q40962491 |
| | The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches | Q41107984 |
| | Differential expression of tetraspanin superfamily members in dendritic cell subsets. | Q41570164 |
| | Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease | Q41845995 |
| | Emerging mechanisms of molecular pathology in ALS. | Q42404037 |
| | Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma | Q42651961 |
| | LINGO-1 and Neurodegeneration: Pathophysiologic Clues for Essential Tremor | Q43243189 |
| | Downregulation of uridine-cytidine kinase like-1 decreases proliferation and enhances tumor susceptibility to lysis by apoptotic agents and natural killer cells | Q43298963 |
| | Neuroprotective effects of pyruvate in the quinolinic acid rat model of Huntington's disease | Q44614374 |
| | Regulatory T cells constrain the TCR repertoire of antigen-stimulated conventional CD4 T cells | Q47269379 |
| | Neuron-specific alternative splicing of transcriptional machineries: Implications for neurodevelopmental disorders | Q47279488 |
| | Calcitriol regulates immune genes CD14 and CD180 to modulate LPS responses in human trophoblasts | Q47580725 |
| | Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice. | Q47623937 |
| | Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production | Q47738457 |
| | IL-23 Inhibits Melanoma Development by Augmenting DNA Repair and Modulating T Cell Subpopulations | Q48008318 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pathophysiology | Q1135939 |
| | RNA sequencing | Q2542347 |
| | Als | Q165383 |
| | amyotrophic lateral sclerosis | Q206901 |
| P304 | page(s) | 189-204 | |
| P577 | publication date | 2018-07-07 | |
| P1433 | published in | Neurogenetics | Q15710048 |
| P1476 | title | FUS(1-359) transgenic mice as a model of ALS: pathophysiological and molecular aspects of the proteinopathy | |
| P478 | volume | 19 | |