Manipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis.

scientific article published on 14 June 2019

Manipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FIMMU.2019.01374
P932PMC publication ID6587398
P698PubMed publication ID31258540

P50authorFrancisco Carrillo-SalinasQ56241066
P2093author name stringCarmen Guaza
Leyre Mestre
Miriam Mecha
Carmen Espejo
Ana Feliú
Luisa María Villar
José Carlos Álvarez-Cermeño
P2860cites workQIIME allows analysis of high-throughput community sequencing dataQ24616873
Theiler's virus infection: a model for multiple sclerosisQ24629115
"Microglial nodules" and "newly forming lesions" may be a Janus face of early MS lesions; implications from virus-induced demyelination, the Inside-Out modelQ26779366
The role of gut microbiota in immune homeostasis and autoimmunityQ26860722
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasisQ29547656
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequencesQ29615050
Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitisQ29619978
2-Arachidonoylglycerol Reduces Proteoglycans and Enhances Remyelination in a Progressive Model of Demyelination.Q40104988
Fingolimod increases CD39-expressing regulatory T cells in multiple sclerosis patientsQ42012792
Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models.Q42221329
Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in miceQ42263596
Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in jointsQ42644114
CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosisQ43241046
An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosisQ43265002
Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity.Q43684750
Antibody response against gastrointestinal antigens in demyelinating diseases of the central nervous system.Q43849229
A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules.Q44124410
Bacteroides fragilis polysaccharide A is necessary and sufficient for acute activation of intestinal sensory neuronsQ44433866
Temporal development of autoreactive Th1 responses and endogenous presentation of self myelin epitopes by central nervous system-resident APCs in Theiler's virus-infected miceQ45740050
Dexamethasone regulation of interleukin-1-receptors in the hippocampus of Theiler's virus-infected mice: effects on virus-mediated demyelinationQ45748847
Persistent infection of oligodendrocytes in Theiler's virus‐induced encephalomyelitisQ45796139
Gut microbiome in multiple sclerosis: The players involved and the roles they play.Q47100520
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific MannerQ47560330
A commensal bacterial product elicits and modulates migratory capacity of CD39(+) CD4 T regulatory subsets in the suppression of neuroinflammationQ48669047
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.Q48819558
Alteration of CD39+Foxp3+ CD4 T cell and cytokine levels in EAE/MS following anti-CD52 treatment.Q51191912
A CB₁/CB₂ receptor agonist, WIN 55,212-2, exerts its therapeutic effect in a viral autoimmune model of multiple sclerosis by restoring self-tolerance to myelin.Q52625009
Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease.Q52759565
Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression.Q54412643
Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease.Q54471973
The human gut microbiome in early-onset type 1 diabetes from the TEDDY studyQ57807205
Targeted Diet Modification Reduces Multiple Sclerosis-like Disease in Adult Marmoset Monkeys from an Outbred ColonyQ57810583
The Gut-Microglia Connection: Implications for Central Nervous System DiseasesQ57817925
Vitamin D–Dependent Rickets, HLA-DRB1, and the Risk of Multiple SclerosisQ57912274
Microbiome-microglia connections via the gut-brain axisQ58559445
Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitisQ84749218
B cells in multiple sclerosisQ88305700
Gut environmental factors and multiple sclerosisQ90753840
Short-chain fatty acids and gut microbiota in multiple sclerosisQ93066507
Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasisQ30920058
A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cellsQ33528981
Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans.Q34360221
Host microbiota constantly control maturation and function of microglia in the CNS.Q34478756
Induction of a regulatory B cell population in experimental allergic encephalomyelitis by alteration of the gut commensal microfloraQ34503563
The microbiota in adaptive immune homeostasis and diseaseQ34533142
Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networksQ34667649
Depletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expressionQ34704203
Multiple sclerosis: an immune or neurodegenerative disorder?Q34786872
Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progressionQ34831296
Epitope spreading and molecular mimicry as triggers of autoimmunity in the Theiler's virus-induced demyelinating disease model of multiple sclerosisQ35172044
STAMP: statistical analysis of taxonomic and functional profiles.Q35212955
Gut microbiome and multiple sclerosis.Q35245013
Peripheral education of the immune system by colonic commensal microbiota.Q35341308
Segregated regulatory CD39+CD4+ T cell function: TGF-β-producing Foxp3- and IL-10-producing Foxp3+ cells are interdependent for protection against collagen-induced arthritisQ35610749
Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV ClustersQ35773313
Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine.Q35816184
Gut microbiota, metabolites and host immunityQ36031926
A commensal symbiotic factor derived from Bacteroides fragilis promotes human CD39(+)Foxp3(+) T cells and Treg functionQ36191738
The dual role of short fatty acid chains in the pathogenesis of autoimmune disease modelsQ36289990
High cell surface expression of CD4 allows distinction of CD4(+)CD25(+) antigen-specific effector T cells from CD4(+)CD25(+) regulatory T cells in murine experimental autoimmune encephalomyelitisQ36401977
Multiple sclerosis patients have a distinct gut microbiota compared to healthy controlsQ37040077
Alterations of the human gut microbiome in multiple sclerosis.Q37060934
NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut floraQ37061082
B-lymphocyte contributions to human autoimmune diseaseQ37211283
Induction of gut regulatory CD39+ T cells by teriflunomide protects against EAE.Q37337770
Gut dysbiosis and neuroimmune responses to brain infection with Theiler's murine encephalomyelitis virus.Q37698703
Environmental factors in multiple sclerosisQ38167388
Microglial diversity by responses and respondersQ38205433
Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analysesQ38348320
Influence of the Gut Microbiome on Autoimmunity in the Central Nervous SystemQ38772593
The influence of gut-derived CD39 regulatory T cells in CNS demyelinating diseaseQ38926183
The gut microbiome in multiple sclerosisQ39021579
Mesenteric lymph nodes contribute to proinflammatory Th17-cell generation during inflammation of the small intestine in miceQ39124619
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P921main subjectmotor disabilityQ106097353
P304page(s)1374
P577publication date2019-06-14
P1433published inFrontiers in ImmunologyQ27723748
P1476titleManipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis
P478volume10