| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.271.45.28612 |
| P698 | PubMed publication ID | 8910492 |
| P2093 | author name string | K L O'Malley | |
| C Romano | |||
| W L Yang | |||
| P433 | issue | 45 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 28612-28616 | |
| P577 | publication date | 1996-11-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Metabotropic glutamate receptor 5 is a disulfide-linked dimer | |
| P478 | volume | 271 |
| Q36983708 | A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization |
| Q28364301 | A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor |
| Q33913403 | A trafficking checkpoint controls GABA(B) receptor heterodimerization |
| Q42059792 | A transmembrane domain-derived peptide inhibits D1 dopamine receptor function without affecting receptor oligomerization |
| Q24290268 | AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration |
| Q38291664 | Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release |
| Q30364526 | Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes. |
| Q34195416 | Activation of Metabotropic Glutamate Receptor mGlu5 on Nuclear Membranes Mediates Intranuclear Ca2+ Changes in Heterologous Cell Types and Neurons |
| Q42495060 | Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. |
| Q60050345 | Adenosine-glutamate receptor-receptor interactions in the central nervous system |
| Q60050346 | Adenosine/dopamine receptor-receptor interactions in the central nervous system |
| Q34469413 | Adrenomedullin and related peptides: receptors and accessory proteins |
| Q34224641 | Advances in the molecular understanding of GABA(B) receptors. |
| Q44447205 | Agonist-independent desensitization and internalization of the human platelet-activating factor receptor by coumermycin-gyrase B-induced dimerization. |
| Q33898787 | Allosteric activation of the CaR by L-amino acids |
| Q28364090 | Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function |
| Q37773480 | Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential |
| Q40179229 | Allosteric modulation of the calcium-sensing receptor |
| Q37420479 | Allosteric modulators for mGlu receptors |
| Q34826248 | Analysis of G-protein-coupled receptor dimerization following chemokine signaling |
| Q45992716 | Assembly-dependent trafficking assays in the detection of receptor-receptor interactions. |
| Q40428691 | Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators. |
| Q34290644 | BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues. |
| Q37440201 | BRI2 homodimerizes with the involvement of intermolecular disulfide bonds. |
| Q37404983 | Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk |
| Q37134357 | Bioluminescence resonance energy transfer studies reveal constitutive dimerization of the human lutropin receptor and a lack of correlation between receptor activation and the propensity for dimerization |
| Q37773024 | Brain receptor mosaics and their intramembrane receptor-receptor interactions: molecular integration in transmission and novel targets for drug development |
| Q40830560 | C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. |
| Q50320977 | Carboxyl-terminal Tail-mediated Homodimerizations of Sphingomyelin Synthases Are Responsible for Efficient Export from the Endoplasmic Reticulum. |
| Q34070596 | Characterization of a truncated metabotropic glutamate receptor in a primitive metazoan, the parasitic flatworm Schistosoma mansoni |
| Q28203529 | Characterization of mGluR5R, a novel, metabotropic glutamate receptor 5-related gene |
| Q34079612 | Chemokine receptor homo- or heterodimerization activates distinct signaling pathways |
| Q38289844 | Cleavage of Ig-Hepta at a "SEA" module and at a conserved G protein-coupled receptor proteolytic site |
| Q41101112 | Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype |
| Q40538867 | Closed state of both binding domains of homodimeric mGlu receptors is required for full activity. |
| Q34036974 | Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists |
| Q65000421 | Computational prediction of homodimerization of the A3 adenosine receptor. |
| Q35588397 | Conformational changes of G protein-coupled receptors during their activation by agonist binding |
| Q64903522 | Conformational dynamics between transmembrane domains and allosteric modulation of a metabotropic glutamate receptor. |
| Q40832497 | Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor |
| Q46083239 | Control of neuronal excitability by Group I metabotropic glutamate receptors |
| Q34360070 | Cooperative signaling between homodimers of metabotropic glutamate receptors 1 and 5 |
| Q96131906 | Cryo-EM structures of inactive and active GABAB receptor |
| Q24290099 | Cys-140 is critical for metabotropic glutamate receptor-1 dimerization |
| Q50308570 | Cysteine residues are essential for dimerization of Hippo pathway components YAP2L and TAZ. |
| Q34180510 | Design strategies for bivalent ligands targeting GPCRs |
| Q35120622 | Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET) |
| Q43512020 | Developmental and sensory-dependent changes of group II metabotropic glutamate receptors |
| Q37293961 | Developmental expression analysis and immunolocalization of a biogenic amine receptor in Schistosoma mansoni |
| Q48158134 | Developmental expression of the group III metabotropic glutamate receptor mGluR4a in the medial nucleus of the trapezoid body of the rat. |
| Q28248856 | Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus |
| Q35035828 | Dimerization of G protein-coupled receptors: CB1 cannabinoid receptors as an example. |
| Q35592680 | Dimerization of G-protein-coupled receptors: roles in signal transduction |
| Q53826195 | Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs. |
| Q43789050 | Discriminative disulfide-bonding affinity labeling of opioid receptor subtypes |
| Q24624255 | Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling |
| Q28513710 | Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites |
| Q28139311 | Distribution of the GABA(B) receptor subunit gb2 in rat CNS |
| Q36191579 | Entropy and oligomerization in GPCRs |
| Q24556662 | Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR |
| Q35143358 | Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors |
| Q40853974 | Expression of metabotropic glutamate receptors in murine thymocytes and thymic stromal cells |
| Q40962035 | Expression, purification, and biochemical characterization of the amino-terminal extracellular domain of the human calcium receptor |
| Q37613651 | Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport |
| Q60956605 | FSHR Trans-Activation and Oligomerization |
| Q36174739 | Functional and pharmacological characteristics of metabotropic glutamate receptors 2/4 heterodimers |
| Q73959987 | Functional coupling of a human retinal metabotropic glutamate receptor (hmGluR6) to bovine rod transducin and rat Go in an in vitro reconstitution system |
| Q34121094 | Functional interaction of G protein-coupled receptors of the adrenomedullin peptide family with accessory receptor-activity-modifying proteins (RAMP). |
| Q73327879 | Functional regulation of metabotropic glutamate receptor type 1c: a role for phosphorylation in the desensitization of the receptor |
| Q33944849 | Functional significance of oligomerization of G-protein-coupled receptors. |
| Q47860164 | G protein-coupled receptors. II. Mechanism of agonist activation |
| Q34502401 | G protein-coupled receptors: dominant players in cell-cell communication |
| Q37829756 | G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand? |
| Q35630448 | G-protein coupled receptor oligomerization in neuroendocrine pathways |
| Q24603239 | G-protein-coupled receptor heterodimerization modulates receptor function |
| Q34371408 | G-protein-coupled receptor heteromer dynamics. |
| Q34932201 | G-protein-coupled receptor oligomerization and its potential for drug discovery |
| Q33896444 | G-protein-coupled receptors function as oligomers in vivo |
| Q40984747 | GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2. |
| Q34485514 | GABA(B)-receptor subtypes assemble into functional heteromeric complexes. |
| Q39909453 | GABA-B(1) receptors are coupled to the ERK1/2 MAP kinase pathway in the absence of GABA-B(2) subunits |
| Q33739386 | GABAB receptors - the first 7TM heterodimers. |
| Q37121338 | Glutamate signaling in benign and malignant disorders: current status, future perspectives, and therapeutic implications |
| Q48391758 | Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? |
| Q37249255 | Glutamate, glutamate receptors, and downstream signaling pathways |
| Q45106035 | Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia. |
| Q26783258 | Growth Hormone Secretagogue Receptor Dimers: A New Pharmacological Target(1,2,3) |
| Q35122994 | Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors. |
| Q22008591 | Heterodimerization is required for the formation of a functional GABA(B) receptor |
| Q34389040 | Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking |
| Q79277470 | Homo- or Hetero-Dimerization of muscarinic receptor subtypes is not mediated by direct protein-protein interaction through intracellular and extracellular regions |
| Q34748827 | Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis |
| Q42604900 | Ig-hepta, a novel member of the G protein-coupled hepta-helical receptor (GPCR) family that has immunoglobulin-like repeats in a long N-terminal extracellular domain and defines a new subfamily of GPCRs |
| Q43181358 | Imaging in vivo glutamate fluctuations with [(11)C]ABP688: a GLT-1 challenge with ceftriaxone |
| Q48219741 | Immunochemical localization of the metabotropic glutamate receptors in the rat heart |
| Q48546715 | Immunocytochemical localization of the mGluR1b metabotropic glutamate receptor in the rat hypothalamus. |
| Q33877819 | Inhibition of N-linked glycosylation of the human type 1alpha metabotropic glutamate receptor by tunicamycin: effects on cell-surface receptor expression and function |
| Q47099606 | Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity. |
| Q34344337 | Insect G protein-coupled receptors and signal transduction |
| Q74746934 | Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia |
| Q35061467 | Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function |
| Q34701303 | International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update |
| Q37663163 | Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus |
| Q36054635 | Ionotropic and metabotropic glutamate receptor structure and pharmacology |
| Q28373018 | Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor |
| Q77950907 | Ligand efficacy and affinity in an interacting 7TM receptor model |
| Q41090393 | Light and electron microscopic demonstration of mGluR5 metabotropic glutamate receptor immunoreactive neuronal elements in the rat cerebellar cortex |
| Q30840472 | Localization of metabotropic glutamate receptor type 2 in the human brain |
| Q34573953 | Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5. |
| Q35831877 | Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS. |
| Q48103150 | Loss of metabotropic glutamate receptor-dependent long-term depression via downregulation of mGluR5 after status epilepticus |
| Q41953851 | Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors |
| Q27628494 | Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core |
| Q33695742 | Metabotropic G-protein-coupled glutamate receptors as therapeutic targets |
| Q37723772 | Metabotropic glutamate receptor subtype 5 antagonism in learning and memory |
| Q38567309 | Metabotropic glutamate receptor subtype 5: molecular pharmacology, allosteric modulation and stimulus bias |
| Q52616941 | Metabotropic glutamate receptor trafficking. |
| Q30448778 | Metabotropic glutamate receptors: from the workbench to the bedside |
| Q34548734 | Methods used to study the oligomeric structure of G-protein-coupled receptors |
| Q32140641 | Molecular determinants of metabotropic glutamate receptor signaling. |
| Q42700069 | Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222. |
| Q50719477 | Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit. |
| Q44545611 | Molecular similarities in the ligand binding pockets of an odorant receptor and the metabotropic glutamate receptors |
| Q24534016 | Molecular tinkering of G protein-coupled receptors: an evolutionary success |
| Q40997378 | Mutational analysis of the cysteines in the extracellular domain of the human Ca2+ receptor: effects on cell surface expression, dimerization and signal transduction |
| Q26773431 | Neurobiological Insights from mGlu Receptor Allosteric Modulation |
| Q37136050 | New aspects of G-protein-coupled receptor signalling and regulation |
| Q33709295 | New perspectives for the development of selective metabotropic glutamate receptor ligands. |
| Q24301599 | Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking |
| Q42428591 | Oligomeric forms of G protein-coupled receptors (GPCRs). |
| Q28202455 | Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation |
| Q34232914 | Oligomerization of G-protein-coupled receptors: lessons from the yeast Saccharomyces cerevisiae |
| Q34205602 | Oligomerization of G-protein-coupled transmitter receptors. |
| Q55666818 | Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics. |
| Q28178824 | Oligomerization of adenosine A2A and dopamine D2 receptors in living cells |
| Q37739478 | On the expanding terminology in the GPCR field: the meaning of receptor mosaics and receptor heteromers. |
| Q34399823 | Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders |
| Q37237034 | Optical measurement of mGluR1 conformational changes reveals fast activation, slow deactivation, and sensitization. |
| Q33756933 | Pharmacological agents acting at subtypes of metabotropic glutamate receptors |
| Q38698653 | Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells |
| Q37183072 | Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors |
| Q49110267 | Presynaptic clustering of mGluR7a requires the PICK1 PDZ domain binding site. |
| Q38209092 | Progress toward advanced understanding of metabotropic glutamate receptors: structure, signaling and therapeutic indications |
| Q35083764 | Proteins interactions implicated in AMPA receptor trafficking: a clear destination and an improving route map. |
| Q54049523 | Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors. |
| Q40825828 | Regulation of angiotensin II type 1 (AT1) receptor function |
| Q36211046 | Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway. |
| Q33719668 | Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation. |
| Q39261780 | Rethinking metabotropic glutamate receptor 5 pathological findings in psychiatric disorders: implications for the future of novel therapeutics. |
| Q34313774 | Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice |
| Q24629746 | Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS |
| Q28371036 | Serotonin 5-HT1B and 5-HT1D receptors form homodimers when expressed alone and heterodimers when co-expressed |
| Q34513871 | Seven in absentia homolog 1A mediates ubiquitination and degradation of group 1 metabotropic glutamate receptors |
| Q58448612 | Somatostatin receptors |
| Q99350034 | Stoichiometric analysis of protein complexes by cell fusion and single molecule imaging |
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| Q27627995 | Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor |
| Q47653448 | Structural biology of GABAB receptor |
| Q27680758 | Structural mechanism of ligand activation in human GABAB receptor |
| Q29465814 | Structural mechanism of ligand activation in human calcium-sensing receptor. |
| Q28362372 | Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors |
| Q35172787 | Structure of the metabotropic glutamate receptor |
| Q40477512 | Subcellular distribution of GABA(B) receptor homo- and hetero-dimers. |
| Q43293591 | Synaptic plasticity in the adult visual cortex is regulated by the metabotropic glutamate receptor, mGluR5. |
| Q73409115 | Synthesis of the nanomolar photoaffinity GABA(B) receptor ligand CGP 71872 reveals diversity in the tissue distribution of GABA(B) receptor forms |
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