Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans

scientific article published on 01 September 1997

Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM0997-1029
P698PubMed publication ID9288733

P2093author name stringK Nakao
H Nishimura
I Tanaka
H Masuzaki
T Mori
K Hosoda
Y Ogawa
T Matsumoto
Y Yoshimasa
N Sagawa
H Mise
P2860cites workEvidence against either a premature stop codon or the absence of obese gene mRNA in human obesityQ22241899
Positional cloning of the mouse obese gene and its human homologueQ22251285
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptinQ28115346
Serum immunoreactive-leptin concentrations in normal-weight and obese humansQ29617230
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjectsQ29617231
Weight-reducing effects of the plasma protein encoded by the obese geneQ29617934
Effects of the obese gene product on body weight regulation in ob/ob miceQ29617935
Role of leptin in the neuroendocrine response to fastingQ29618866
Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin actionQ34289416
Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networksQ34301257
Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesityQ35763700
Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) ratsQ38291957
Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissueQ38293741
Leptin in human reproduction: serum leptin levels in pregnant and lactating womenQ38348913
Modulators of cyclic AMP metabolism induce syncytiotrophoblast formation in vitroQ41746072
Development of radioimmunoassay for human leptinQ71054458
Early onset of reproductive function in normal female mice treated with leptinQ71920050
P433issue9
P304page(s)1029-1033
P577publication date1997-09-01
P1433published inNature MedicineQ1633234
P1476titleNonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans
P478volume3

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cites work (P2860)
Q3428764420 years of leptin: leptin and reproduction: past milestones, present undertakings, and future endeavors
Q50337016A peptide derived from the human leptin molecule is a potent inhibitor of the leptin receptor function in rabbit endometrial cells
Q47320883A physiological role of breast milk leptin in body weight control in developing infants
Q48020409A positive umbilical venous-arterial difference of leptin level and its rapid decline after birth
Q61845074ADIPOKINES AND PATHOPHYSIOLOGY OF PREGNANCY COMPLICATIONS – THE ROLE OF LEPTIN AND ADIPONECTIN
Q38344385Aberrant expression and possible involvement of the leptin receptor in endometrial cancer
Q36753787Adipocyte Versus Somatotrope Leptin: Regulation of Metabolic Functions in the Mouse.
Q34343034Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin.
Q35689443Adipocyte, adipose tissue, and infectious disease
Q55379535Adipokine-myokine-hepatokine compartment-system in mothers and children: An explorative study.
Q34346254Adipose lineage specification of bone marrow-derived myeloid cells
Q33826224Adiposity and hyperleptinemia during the first trimester among pregnant women with preeclampsia
Q91972559Altered expression of leptin and leptin receptor in the development of immune-mediated aplastic anemia in mice
Q73269348Amniotic fluid and maternal serum leptin levels in pregnant women who subsequently develop preeclampsia
Q32062609Antecedent protein restriction and high-fat feeding interactively sensitise the leptin response to elevated insulin
Q28572926Apical leptin induces chloride secretion by intestinal epithelial cells and in a rat model of acute chemotherapy-induced colitis
Q35140191Appetite and energy balance signals from adipocytes.
Q47556870Association between Fetal Adipokines and Child Behavioral Problems at Preschool Age: The Hokkaido Study on Environment and Children's Health.
Q41970199Association between Serum Thyroid-Stimulating Hormone Levels and Visceral Adipose Tissue: A Population-Based Study in Northeast Germany
Q24594235Association of leptin genetic polymorphism -2548 G/A with gestational diabetes mellitus
Q43131840Association of plasma leptin levels with maternal body weight and body mass index in premature and term newborns
Q40868840Association of prenatal antibiotics with foetal size and cord blood leptin and adiponectin
Q58562505Associations of cord blood leptin and adiponectin with children's cognitive abilities
Q45270298Biomarkers and Perceived Emotional Stress in Early-Stage Pregnant Taiwanese Women With Nausea and Vomiting
Q35097848Breast milk hormones and regulation of glucose homeostasis
Q39649484Butyrate regulates leptin expression through different signaling pathways in adipocytes
Q36270015Capacity for hormone production of cultured trophoblast cells obtained from placentae at term and in early pregnancy
Q36508918Cerebrospinal fluid levels of leptin, proopiomelanocortin, and agouti-related protein in human pregnancy: evidence for leptin resistance
Q74509509Characterization of human villous and extravillous trophoblasts isolated from first trimester placenta
Q35622378Chronic hyperleptinemia results in the development of hypertension in pregnant rats
Q50779981Circadian Rhythms in Adipose Tissue Physiology.
Q42449710Cold exposure does not decrease serum leptin concentration, but increases energy intake and thermogenic capacity in pregnant Brandt's voles (Lasiopodomys brandtii).
Q48331690Comparative analysis of expression and secretion of placental leptin in mammals
Q84615610Comparison of Serum Levels and the Placental Expression of Resistin Between Patients with Preeclampsia and Normal Pregnant Women
Q55068256Concentrations of leptin in the serum of pregnant, lactating, and cycling rats and of leptin messenger ribonucleic acid in rat placental tissue.
Q36661713Consequences of stopping and restarting leptin in an adolescent with lipodystrophy
Q92218369Cord blood leptin DNA methylation levels are associated with macrosomia during normal pregnancy
Q40806850Cord blood leptin concentrations in relation to intrauterine growth
Q34345275Cord blood leptin levels of healthy neonates are associated with IFN-γ production by cord blood T-cells
Q42288208Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes
Q35358652Curcumin inhibits leptin gene expression and secretion in breast cancer cells by estrogen receptors
Q33808147Current concepts concerning the role of leptin in reproductive function
Q35048767Cytokines during early pregnancy of mammals: a review
Q33992406Developmental gene x environment interactions affecting systems regulating energy homeostasis and obesity
Q33570736Different indices of fetal growth predict bone size and volumetric density at 4 years of age.
Q51768539Differential effects of undernourishment and nutritional rehabilitation on serum leptin levels in male and female rats.
Q35897949Direct effects of leptin and adiponectin on peripheral reproductive tissues: a critical review
Q38289239Distribution of the long leptin receptor isoform in brush border, basolateral membrane, and cytoplasm of enterocytes.
Q37787474Disturbances in lipid metabolism in diabetic pregnancy – Are these the cause of the problem?
Q46710236Do adiponectin, TNFalpha, leptin and CRP relate to insulin resistance in pregnancy? Studies in women with and without gestational diabetes, during and after pregnancy
Q35794971Does leptin link sleep loss and breathing disturbances with major public diseases?
Q38946988Early Pregnancy Biochemical Predictors of Gestational Diabetes Mellitus
Q46671666Early postnatal leptin blockage leads to a long-term leptin resistance and susceptibility to diet-induced obesity in rats.
Q33320341Effect of Lactobacillus acidophilus supernatants on body weight and leptin expression in rats
Q38303067Effect of alcohol consumption on leptin level in serum, adipose tissue, and gastric mucosa
Q40657258Effect of leptin in proliferating and differentiated HC11 mouse mammary cells.
Q35842130Effect of placental function on fatty acid requirements during pregnancy
Q30392622Effects of Gestational Magnetic Resonance Imaging on Methylation Status of Leptin Promoter in the Placenta and Cord Blood
Q48703455Effects of food restriction on glucose tolerance, insulin secretion, and islet-cell proliferation in pregnant rats
Q30432172Effects of glucose and insulin on acyl ghrelin and desacyl ghrelin, leptin, and adiponectin in pregnant women with diabetes
Q60647867Effects of lactation on metabolic and reproductive hormones in Lipizzaner mares
Q73739499Effects of leptin gene expression in mice in vivo by electroporation and hydrodynamics-based gene delivery
Q37414248Effects of leptin on in vitro maturation, fertilization and embryonic cleavage after ICSI and early developmental expression of leptin (Ob) and leptin receptor (ObR) proteins in the horse
Q80727278Effects of leptin on stress-induced changes of caspases in rat gastric mucosa
Q40632224Effects of leptin on the production of cytokines by cultured human endometrial stromal and epithelial cells
Q43807132Effects of leptin, interleukin-1alpha, interleukin-6, and transforming growth factor-beta on markers of trophoblast invasive phenotype: integrins and metalloproteinases
Q47155087Effects of maternal and fetal LEP common variants on maternal glycemic traits in pregnancy
Q73492100Effects of pregnancy and exercise on concentrations of the metabolic markers tumor necrosis factor alpha and leptin
Q73035323Elevated leptin concentrations in pregnancy and lactation: possible role as a modulator of substrate utilization
Q36539670Energy metabolism and the skeleton: Reciprocal interplay
Q58924015Evaluation of leptin in breast milk, lactating mothers and their infants
Q34064535Evidence for positive selection on the leptin gene in Cetacea and Pinnipedia
Q74437886Evidence of free leptin in human seminal plasma
Q38354354Exogenous leptin inhibits the secretion of pancreatic juice via a duodenal CCK1-vagal-dependent mechanism in anaesthetized rats
Q44653478Expression of Nitric Oxide Synthase Isoforms in the Human Placenta Is Not Altered by Labor
Q90582799Expression of leptin and leptin receptors in colorectal cancer-an immunohistochemical study
Q38445569Expression of leptin and leptin receptors in gestational trophoblastic diseases.
Q38309850Expression of obesity gene and obesity gene long form receptor in endometrium of Yorkshire sows during embryo implantation
Q51490251Expression of resistin protein in normal human subcutaneous adipose tissue and pregnant women subcutaneous adipose tissue and placenta.
Q38311378Expression of the long form of leptin receptor (Ob-Rb) mRNA in the brain of mouse embryos and newborn mice
Q44406686Fat accumulation in the rat during early pregnancy is modulated by enhanced insulin responsiveness
Q35110801Fetal hypothalamic neuroprogenitor cell culture: preferential differentiation paths induced by leptin and insulin
Q73228431Fetal pancreatic islets express functional leptin receptors and leptin stimulates proliferation of fetal islet cells
Q34393416Food intake and leptin during pregnancy and lactation
Q36661530Food-intake-regulating-neuropeptides are expressed and regulated through pregnancy and following food restriction in rat placenta
Q47404508Free-to-Total Leptin Ratio in Maternal Plasma is Constant Throughout Human Pregnancy
Q37011600From feeding one to feeding many: hormone-induced changes in bodyweight homeostasis during pregnancy
Q33539460From lesions to leptin: hypothalamic control of food intake and body weight.
Q92376983Gastric Leptin and Tumorigenesis: Beyond Obesity
Q77814941Gastric leptin
Q28346245Gastric leptin and Helicobacter pylori infection
Q28209374Gastric leptin: a putative role in the short-term regulation of food intake
Q37367758Gender, smoking during pregnancy and gestational age influence cord leptin concentrations in newborn infants.
Q40285927Genetic determinants of adiponectin regulation revealed by pregnancy
Q37555100Genetic variation in leptin and leptin receptor genes is a risk factor for idiopathic recurrent spontaneous abortion.
Q24795251Glucose-stimulated insulin response in pregnant sheep following acute suppression of plasma non-esterified fatty acid concentrations
Q47988229High leptin in pregnant mink (Mustela vison) may exert anorexigenic effects: a permissive factor for rapid increase in food intake during lactation
Q36714981Higher maternal leptin levels at second trimester are associated with subsequent greater gestational weight gain in late pregnancy
Q44376057Human leptin promotes survival of human circulating blood monocytes prone to apoptosis by activation of p42/44 MAPK pathway
Q35197842Human placenta as an endocrine organ
Q38335561Hyperleptinaemia in mice induced by administration of the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine.
Q73979628Hyperleptinemia in pregnant bats is characterized by increased placental leptin secretion in vitro
Q51728062Hypoxia inhibits leptin production by cultured rat adipocytes.
Q34288655IL-6-like cytokines and cancer cachexia: consequences of chronic inflammation
Q54353294ITIH-5 expression in human adipose tissue is increased in obesity.
Q42518831Immunocytochemical detection of leptin-like immunoreactivity in the chicken gastroenteric tract.
Q33856945Impaired fracture healing with high non-union rates remains irreversible after traumatic brain injury in leptin-deficient mice
Q36369223Inhibition of leptin gene expression and secretion by silibinin: possible role of estrogen receptors.
Q80179824Inhibition of trophoblast invasiveness in vitro by immunoneutralization of leptin in the bat, Myotis lucifugus (Chiroptera)
Q24291280Insulin and glucocorticoids differentially regulate leptin transcription and secretion in brown adipocytes
Q54105933Insulin resistance, impaired glucose tolerance and non-insulin-dependent diabetes, pathologic mechanisms and treatment: current status and therapeutic possibilities.
Q35184288Intermediate metabolism in normal pregnancy and in gestational diabetes.
Q36334963Intracellular signalling pathways activated by leptin
Q51533378Intracerebroventricular Administration of Leptin-Induced Apoptosis in the Rat Small Intestinal Mucosa
Q78564110Intralobular ducts of human major salivary glands contain leptin and its receptor
Q33535927Involvement of transcription factor NR2F2 in human trophoblast differentiation.
Q26851558Is there a link between obesity and asthma?
Q57244364Leptin
Q59216161Leptin
Q47379359Leptin action in normal and pathological pregnancies
Q38306983Leptin activates Stat3, Stat1 and AP-1 in mouse adipose tissue
Q38153628Leptin and adiponectin: emerging therapeutic targets in breast cancer
Q89859670Leptin and ghrelin expressions in the gastrointestinal tracts of calves and cows
Q37732818Leptin and its emerging role in children and adolescents
Q38330261Leptin and its receptors: regulators of whole-body energy homeostasis
Q36470247Leptin and its role in hippocampal synaptic plasticity
Q34514792Leptin and leptin receptor in anterior pituitary function
Q86450633Leptin and leptin receptor polymorphisms and recurrent pregnancy loss
Q25257264Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma
Q34548469Leptin and reproduction: a review
Q38291788Leptin and the obesity receptor (OB-R) in the small intestine and colon: a colocalization study
Q34514780Leptin and the pituitary
Q29615976Leptin and the regulation of body weight in mammals
Q34548531Leptin and the regulation of food intake, energy homeostasis and immunity with special focus on periparturient ruminants
Q34635461Leptin and the treatment of obesity: its current status
Q38337157Leptin and vascular endothelial growth factor regulate angiogenesis in tooth germs
Q26865989Leptin as regulator of pulmonary immune responses: involvement in respiratory diseases
Q38319858Leptin concentrations in maternal serum and amniotic fluid during the second trimenon: differential relation to fetal gender and maternal morphometry
Q43614898Leptin decreases feeding and exploratory behaviour via interactions with CCK(1) receptors in the rat.
Q57671401Leptin during and after preeclamptic or normal pregnancy: Its relation to serum insulin and insulin sensitivity
Q36236092Leptin gene polymorphisms and their phenotypic associations
Q37778403Leptin gene therapy in the fight against diabetes
Q57744801Leptin in first trimester pregnancy serum: no reduction associated with small-for-gestational-age infants
Q48497021Leptin in human plasma is derived in part from the brain, and cleared by the kidneys
Q42824521Leptin in human pregnancy: the relationship with gestational hormones
Q34514798Leptin in pituitary adenomas--a novel paracrine regulatory system.
Q33702042Leptin in renal failure
Q34135055Leptin in reproduction.
Q35119544Leptin in the CNS: much more than a satiety signal.
Q35174370Leptin in the canine uterus and placenta: possible implications in pregnancy
Q36587716Leptin in the field of hepatic fibrosis: a pivotal or an incidental player?
Q35945101Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF.
Q28116312Leptin inhibits glucose intestinal absorption via PKC, p38MAPK, PI3K and MEK/ERK
Q43975329Leptin inhibits stress-induced apoptosis of T lymphocytes
Q37405717Leptin interferes with 3',5'-cyclic adenosine monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells
Q38307707Leptin is a potent stimulator of bone growth in ob/ob mice
Q33749053Leptin is an anti-apoptotic effector in placental cells involving p53 downregulation
Q51554848Leptin levels in relation to body composition and insulin concentration in patients with endogenous Cushing's syndrome compared to controls matched for body mass index.
Q73082544Leptin levels vary significantly during the menstrual cycle, pregnancy, and in vitro fertilization treatment: possible relation to estradiol
Q37635800Leptin pharmacokinetics in male mice.
Q35044712Leptin potentiates IFN-gamma-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1.
Q33954875Leptin potentiates Prevotella intermedia lipopolysaccharide-induced production of TNF-alpha in monocyte-derived macrophages
Q73920272Leptin production by hydatidiform mole
Q33112091Leptin promotes fetal lung maturity and upregulates SP-A expression in pulmonary alveoli type-II epithelial cells involving TTF-1 activation
Q28540838Leptin promotes wound healing in the oral mucosa
Q28544888Leptin promotes wound healing in the skin
Q38287422Leptin receptor (Ob-R) expression is induced in peripheral blood mononuclear cells by in vitro activation and in vivo in HIV-infected patients.
Q36530544Leptin receptor signaling is required for high-fat diet-induced atrophic gastritis in mice
Q42947348Leptin regulates MMP-2, TIMP-1 and collagen synthesis via p38 MAPK in HL-1 murine cardiomyocytes
Q35360626Leptin secretion and leptin receptor in the human stomach
Q38293046Leptin signal transduction in the HP75 human pituitary cell line.
Q36576492Leptin signaling and Alzheimer's disease
Q35630443Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance
Q38703387Leptin signalling pathways in hypothalamic neurons
Q38347729Leptin stimulates the oxidative burst in control monocytes but attenuates the oxidative burst in monocytes from HIV-infected patients
Q36094992Leptin system in embryo development and implantation: a protein in search of a function
Q77582769Leptin upregulates beta3-integrin expression and interleukin-1beta, upregulates leptin and leptin receptor expression in human endometrial epithelial cell cultures
Q43851456Leptin's sexual dimorphism results from genotype by sex interactions mediated by testosterone
Q36101219Leptin, adiponectin and pulmonary diseases
Q81094855Leptin, ghrelin and TNF-alpha before and after hypo-caloric traditional Chinese diet and auricular acupuncture
Q34514821Leptin, reproduction and sex steroids
Q37351155Leptin-cytokine crosstalk in breast cancer.
Q35622301Leptin: a multifaceted hormone in the central nervous system.
Q34056731Leptin: a possible link between food intake, energy expenditure, and reproductive function.
Q34548538Leptin: a possible metabolic signal affecting reproduction
Q56169405Leptin: a review of its peripheral actions and interactions
Q34028111Leptin: pathogenesis and treatment of morbid obesity
Q36208881Limits to sustained energy intake IX: a review of hypotheses
Q33873705Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression
Q37520261Long chain fatty acids and dietary fats in fetal nutrition
Q47175179Long-lived weight-reduced αMUPA mice show higher and longer maternal-dependent postnatal leptin surge
Q90262231Longitudinal changes in adipokines and free leptin index during and after pregnancy in women with obesity
Q72989771Macrosomia revisited: ponderal index and leptin delineate subtypes of fetal overgrowth
Q26827131Maternal circulating concentrations of tumor necrosis factor-alpha, leptin, and adiponectin in gestational diabetes mellitus: a systematic review and meta-analysis
Q35579461Maternal diabetes in pregnancy: early and long-term outcomes on the offspring and the concept of "metabolic memory"
Q35134214Maternal factors that determine neonatal size and body fat.
Q43755837Maternal leptin is elevated during pregnancy in sheep
Q34246872Maternal leptin, adiponectin, resistin, visfatin and tumor necrosis factor-alpha in normal and gestational diabetes
Q90695527Maternal programming: Application of a developmental psychopathology perspective
Q77840270Maternal serum leptin concentration during the second trimester of pregnancy: association with fetal chromosomal abnormalities
Q36962864Maternal serum leptin during pregnancy and infant birth weight: the influence of maternal overweight and obesity
Q38073158Maternal/fetal determinants of insulin resistance in women during pregnancy and in offspring over life
Q48715094Metabolic control of sexual function and growth: role of neuropeptide Y and leptin
Q44644600Mice body weight gain is prevented after naked human leptin cDNA transfer into skeletal muscle by electroporation
Q37731246Mid-pregnancy maternal leptin levels, birthweight for gestational age and preterm delivery
Q38311370Molecular cloning and properties of the chicken leptin-receptor (CLEPR) gene.
Q64243637Molecular dynamic (MD) studies on Gln233Arg (rs1137101) polymorphism of leptin receptor gene and associated variations in the anthropometric and metabolic profiles of Saudi women
Q34514788Neuroendocrine effects of leptin
Q35875387Obesity-related known and candidate SNP markers can significantly change affinity of TATA-binding protein for human gene promoters
Q34290268Olfaction under metabolic influences.
Q26861403Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
Q73784082One-step enzyme-linked immunosorbent assay (ELISA) for measurement of serum free leptin
Q38310706Ontogeny of the expression of leptin and its receptor in the murine fetus and placenta
Q36007397Oxidative stress, gene expression, and protein changes induced in the human placenta during labor
Q34568669Paracrine dialogue in implantation
Q28364469PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine
Q60660385Perinatal expression of leptin in rat stomach
Q35204654Peripheral mechanisms in appetite regulation
Q36753785Peripheral tissue-brain interactions in the regulation of food intake
Q36600471Physiology and gene regulation of the brain NPY Y1 receptor
Q94550650Placental expression of leptin: fetal sex-independent relation with human placental growth
Q37239694Plasma Leptin Is Elevated in Acute Exacerbation of Idiopathic Pulmonary Fibrosis.
Q35535129Plasma leptin levels and cardiac sympathetic function in patients with obstructive sleep apnoea-hypopnoea syndrome
Q35605865Plasma levels of leptin and mammographic density among postmenopausal women: a cross-sectional study
Q28206409Possible interactions between leptin, gonadotrophin-releasing hormone (GnRH-I and II) and human chorionic gonadotrophin (hCG)
Q44535628Possible involvement of inositol phosphoglycan-P in human parturition
Q35065095Possible role of placental leptin in pregnancy: a review
Q28346557Postnatal changes in concentrations of free and bound leptin
Q35124551Postnatal leptin is necessary for maturation of numerous organs in newborn rats
Q37378639Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function
Q36830035Potential mechanisms of exercise in gestational diabetes
Q36117963Preventing and treating obesity in pediatrics through physical activity
Q34381500Pulling strings below the surface: hormone receptor signaling through inhibition of protein tyrosine phosphatases
Q40280686RNA interference targeting leptin gene effect on hepatic stellate cells
Q34287286Regulation of placental calcium transport and offspring bone health.
Q38865986Relationship between leptin levels and suppressed CD4 counts in HIV patients.
Q73213698Relationship of serum leptin levels and selected nutritional parameters in patients with protein-caloric malnutrition
Q47730674Resistin is expressed in different rat tissues and is regulated in a tissue- and gender-specific manner
Q35895869Role of adipokines and other inflammatory mediators in gestational diabetes mellitus and previous gestational diabetes mellitus
Q35161166Role of leptin as an immunomodulator of blood mononuclear cells: mechanisms of action
Q46714355Role of leptin in the regulation of growth and carbohydrate metabolism in the ovine fetus during late gestation
Q40621896Role of leptin present in maternal milk in the control of energy balance during the post-natal period
Q34506531Secretion of adiponectin by human placenta: differential modulation of adiponectin and its receptors by cytokines
Q46632362Secretion of leptin throughout pregnancy and early postpartum period in Japanese monkeys: placenta as another potential source of leptin
Q61316840Secretory granules of endocrine and chief cells of human stomach mucosa contain leptin
Q47163438Serum leptin and skeletal differences between obese and non-obese patients with chronic obstructive pulmonary disease
Q73931079Serum leptin levels in patients with hyperlipidemias
Q80598368Serum leptin levels in patients with nasal polyposis
Q35252411Serum leptin levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in normal pregnancy and preeclampsia
Q35079373Serum leptin measured in early pregnancy is higher in women with preeclampsia compared with normotensive pregnant women
Q36406037Siglec-6 is expressed in gestational trophoblastic disease and affects proliferation, apoptosis and invasion
Q40994445Standardization of amniotic fluid leptin levels and utility in maternal overweight and fetal undergrowth
Q30454422Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women.
Q34719817Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways: implications for leptin as a regulator of short term satiety
Q59823590Systemic administration of lipopolysaccharide increases plasma leptin levels
Q34876259Systemic and placental leptin and its receptors in pregnancies associated with obesity
Q58114519The Pathophysiology of Gestational Diabetes Mellitus
Q37729594The Relationship between Maternal Plasma Leptin and Adiponectin Concentrations and Newborn Adiposity
Q58769072The Role of Placental Hormones in Mediating Maternal Adaptations to Support Pregnancy and Lactation
Q34441228The alternative Epac/cAMP pathway and the MAPK pathway mediate hCG induction of leptin in placental cells
Q78060115The effect of leptin on Lep expression is tissue-specific and nutritionally regulated
Q38331107The gingiva contains leptin and leptin receptor in health and disease
Q41689705The glucoregulatory actions of leptin
Q37589770The impact of diet during early life and its contribution to later disease: critical checkpoints in development and their long-term consequences for metabolic health
Q26865196The impact of leptin on perinatal development and psychopathology
Q84774642The influence of overweight and obesity on longitudinal trends in maternal serum leptin levels during pregnancy
Q36912136The influence of overweight and obesity on maternal soluble fms-like tyrosine kinase 1 and its relationship with leptin during pregnancy
Q38303737The intake of physiological doses of leptin during lactation in rats prevents obesity in later life
Q26861527The integrative role of leptin, oestrogen and the insulin family in obesity-associated breast cancer: potential effects of exercise
Q33815433The molecular mechanism of leptin secretion and expression induced by aristolochic acid in kidney fibroblast
Q33570320The prolonged effect of repeated maternal glucocorticoid exposure on the maternal and fetal leptin/insulin-like growth factor axis in Papio species
Q73677573The reproductive side of leptin
Q34335412The role of leptin in the respiratory system: an overview
Q27008068The role of placental nutrient sensing in maternal-fetal resource allocation
Q35794877The source of leptin, but not leptin depletion in response to food restriction, changes during early pregnancy in mice
Q38333780The stomach is a source of leptin
Q36146612The unfolding tale of leptin
Q37227602Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors
Q40777325Transcriptional effect of hypoxia on placental leptin
Q40804073Transcriptional regulation of the leptin gene promoter in rat GH3 pituitary and C6 glioma cells
Q37591961Translational research of novel hormones: lessons from animal models and rare human diseases for common human diseases
Q44197596Unopposed orexic pathways in the developing fetus
Q78225638Up-regulation of uterine UCP2 and UCP3 in pregnant rats
Q54945689Uterine artery leptin receptors during the ovarian cycle and pregnancy regulate angiogenesis in ovine uterine artery endothelial cells†.
Q80804574[Meningococcal sepsis in pediatrics. Parameters associated with poor outcome]
Q74563668[Placenta and trisomy 21]
Q74563663[Placental leptin and pregnancy pathologies]

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