| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/1529-0131(200004)43:4<801::AID-ANR10>3.0.CO;2-4 |
| P698 | PubMed publication ID | 10765924 |
| P2093 | author name string | Brinckerhoff CE | |
| Barchowsky A | |||
| Vincenti MP | |||
| Coon CI | |||
| Mengshol JA | |||
| P433 | issue | 4 | |
| P304 | page(s) | 801-811 | |
| P577 | publication date | 2000-04-01 | |
| P1433 | published in | Arthritis and Rheumatism | Q23929027 |
| P1476 | title | Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3 | |
| P478 | volume | 43 |
| Q52866845 | A Chemically Modified Curcumin (CMC 2.24) Inhibits Nuclear Factor κB Activation and Inflammatory Bone Loss in Murine Models of LPS-Induced Experimental Periodontitis and Diabetes-Associated Natural Periodontitis. |
| Q28548654 | A Novel Synthesized Sulfonamido-Based Gallate-JEZ-C as Potential Therapeutic Agents for Osteoarthritis |
| Q89690936 | A cyclic pathway of P2 × 7, bradykinin, and dopamine receptor activation induces a sustained articular hyperalgesia in the knee joint of rats |
| Q21245660 | A hexadecylamide derivative of hyaluronan (HYMOVIS®) has superior beneficial effects on human osteoarthritic chondrocytes and synoviocytes than unmodified hyaluronan |
| Q37122058 | A probabilistic approach to learn chromatin architecture and accurate inference of the NF-κB/RelA regulatory network using ChIP-Seq. |
| Q44733625 | A role for chemokines in the induction of chondrocyte phenotype modulation. |
| Q37657974 | AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice |
| Q24336840 | ANKRD1 acts as a transcriptional repressor of MMP13 via the AP-1 site |
| Q34364851 | Aciculatin inhibits granulocyte colony-stimulating factor production by human interleukin 1β-stimulated fibroblast-like synoviocytes. |
| Q26852836 | Acquiring chondrocyte phenotype from human mesenchymal stem cells under inflammatory conditions |
| Q42096174 | Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage |
| Q42249248 | Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study |
| Q90192057 | Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression |
| Q52958424 | An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells. |
| Q38817800 | An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis |
| Q47331819 | Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL-1β/NF-κB pathway. |
| Q55331850 | Annexin A6 regulates catabolic events in articular chondrocytes via the modulation of NF-κB and Wnt/ß-catenin signaling. |
| Q33584720 | Anti-IL-20 monoclonal antibody inhibited inflammation and protected against cartilage destruction in murine models of osteoarthritis |
| Q52571019 | Anti-Inflammatory Effect of Geniposide on Osteoarthritis by Suppressing the Activation of p38 MAPK Signaling Pathway. |
| Q52974832 | Anti-inflammatory and chondroprotective effects of atorvastatin in a cartilage explant model of osteoarthritis. |
| Q41504461 | Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis |
| Q35760099 | Attachment to laminin-111 facilitates transforming growth factor beta-induced expression of matrix metalloproteinase-3 in synovial fibroblasts. |
| Q33953872 | Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes |
| Q37761694 | Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes. |
| Q35380390 | Biomechanical influence of cartilage homeostasis in health and disease |
| Q42566865 | Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB Activation in Canine Articular Chondrocytes |
| Q40507455 | CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion |
| Q30512432 | Caesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes. |
| Q49530657 | Calcium-phosphate complex increased during subchondral bone remodeling affects earlystage osteoarthritis |
| Q51340134 | Carrageenan-induced transient inflammation in a rabbit knee model: molecular changes consistent with an early osteoarthritis phenotype. |
| Q36564849 | Cartilage destruction by matrix degradation products |
| Q55067437 | Celecoxib Combined with Diacerein Effectively Alleviates Osteoarthritis in Rats via Regulating JNK and p38MAPK Signaling Pathways. |
| Q33298079 | Cerebral ischemia induces transcription of inflammatory and extracellular-matrix-related genes in rat cerebral arteries |
| Q35038575 | Chlorogenic acid suppresses interleukin-1β-induced inflammatory mediators in human chondrocytes |
| Q39641161 | Chondro-protective effects of low intensity pulsed ultrasound. |
| Q24793013 | Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition |
| Q46702331 | Chondroprotective effects of glucosamine involving the p38 MAPK and Akt signaling pathways |
| Q36761822 | Chopping off the chondrocyte proteome |
| Q43081525 | Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines |
| Q54633011 | Collagen-induced expression of collagenase-3 by primary chondrocytes is mediated by integrin 1 and discoidin domain receptor 2: a protein kinase C-dependent pathway |
| Q38652392 | Collagenase-3 (MMP-13) deficiency protects C57BL/6 mice from antibody-induced arthritis. |
| Q37394547 | Conditioned media from adipose-tissue-derived mesenchymal stem cells downregulate degradative mediators induced by interleukin-1β in osteoarthritic chondrocytes |
| Q34502025 | Cordycepin modulates inflammatory and catabolic gene expression in interleukin-1beta-induced human chondrocytes from advanced-stage osteoarthritis: an in vitro study |
| Q33637251 | Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis |
| Q84356942 | Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants |
| Q35023088 | Decreasing NF-κB expression enhances odontoblastic differentiation and collagen expression in dental pulp stem cells exposed to inflammatory cytokines |
| Q37331102 | Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism |
| Q47691222 | Depletion of aquaporin 1 decreased ADAMTS‑4 expression in human chondrocytes. |
| Q41965715 | Differential requirements for IKKalpha and IKKbeta in the differentiation of primary human osteoarthritic chondrocytes. |
| Q35668917 | Distal interleukin-1β (IL-1β) response element of human matrix metalloproteinase-13 (MMP-13) binds activator protein 1 (AP-1) transcription factors and regulates gene expression |
| Q38864643 | Distinct Effect of TCF4 on the NFκB Pathway in Human Primary Chondrocytes and the C20/A4 Chondrocyte Cell Line |
| Q36901075 | Docosahexenoic acid treatment ameliorates cartilage degeneration via a p38 MAPK-dependent mechanism |
| Q24793070 | Does protein kinase R mediate TNF-alpha- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism? |
| Q89824730 | Down-regulation of microRNA-203a suppresses IL-1β-induced inflammation and cartilage degradation in human chondrocytes through Smad3 signaling |
| Q55279885 | Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis. |
| Q43294510 | Dynamic compression alters NFkappaB activation and IkappaB-alpha expression in IL-1beta-stimulated chondrocyte/agarose constructs |
| Q39941671 | Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs. |
| Q93005039 | Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis |
| Q35728539 | E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress |
| Q24800017 | Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1beta |
| Q92740308 | Early-Onset Osteoarthritis originates at the chondrocyte level in Hip Dysplasia |
| Q44396572 | Effect of estrogen on the expression of matrix metalloproteinase (MMP)-1, MMP-3, and MMP-13 and tissue inhibitor of metalloproternase-1 in osteoarthritis chondrocytes |
| Q36713889 | Effects of chondroitin sulfate on the cellular metabolism |
| Q46584199 | Effects of sodium selenite on c-Jun N-terminal kinase signalling pathway induced by oxidative stress in human chondrocytes and c-Jun N-terminal kinase expression in patients with Kashin-Beck disease, an endemic osteoarthritis |
| Q91994282 | Embryonic and postnatal tendon cells respond differently to interleukin-1β |
| Q24804001 | Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production |
| Q54615289 | Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage. |
| Q44266578 | Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes |
| Q40733606 | Erk 1/2 differentially regulates the expression from the 1G/2G single nucleotide polymorphism in the MMP-1 promoter in melanoma cells |
| Q35665907 | Eupatilin Exerts Antinociceptive and Chondroprotective Properties in a Rat Model of Osteoarthritis by Downregulating Oxidative Damage and Catabolic Activity in Chondrocytes |
| Q42376847 | Evolution of pain at 3 months by oral resveratrol in knee osteoarthritis (ARTHROL): protocol for a multicentre randomised double-blind placebo-controlled trial |
| Q42104313 | Expression of matrix metalloproteinases and tissue inhibitor metalloproteinases increases in X-irradiated rat ileum despite the disappearance of CD8a T cells. |
| Q47662103 | Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity |
| Q34639810 | Extracellular and intracellular mechanisms of mechanotransduction in three-dimensionally embedded rat chondrocytes |
| Q28070177 | Extracellular vesicles in the pathogenesis of rheumatoid arthritis and osteoarthritis |
| Q37021518 | Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1beta. |
| Q30433820 | Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway |
| Q27025275 | Fluid shear stress-induced osteoarthritis: roles of cyclooxygenase-2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinases |
| Q35908533 | FoxC2 Enhances BMP7-Mediated Anabolism in Nucleus Pulposus Cells of the Intervertebral Disc |
| Q44602463 | Fra‐1 targets the AP‐1 site/2G single nucleotide polymorphism (ETS site) in the MMP‐1 promoter |
| Q34816248 | Function of AP-1 target genes in mesenchymal-epithelial cross-talk in skin |
| Q38330909 | Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes |
| Q37515656 | Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer |
| Q40070187 | Glucosamine affects intracellular signalling through inhibition of mitogen-activated protein kinase phosphorylation in human chondrocytes. |
| Q44175704 | Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes |
| Q44231742 | HIV-1 and IL-1 beta regulate Fas ligand expression in human astrocytes through the NF-kappa B pathway |
| Q34805528 | Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes |
| Q90662117 | High-Frequency Near-Infrared Diode Laser Irradiation Attenuates IL-1β-Induced Expression of Inflammatory Cytokines and Matrix Metalloproteinases in Human Primary Chondrocytes |
| Q41630267 | Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte |
| Q38870768 | Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells |
| Q33945139 | Hyaluronan oligosaccharide-induced activation of transcription factors in bovine articular chondrocytes |
| Q35113980 | Hyaluronan oligosaccharides induce matrix metalloproteinase 13 via transcriptional activation of NFkappaB and p38 MAP kinase in articular chondrocytes |
| Q53604597 | Hyaluronan suppresses mechanical stress-induced expression of catabolic enzymes by human chondrocytes via inhibition of IL-1β production and subsequent NF-κB activation. |
| Q42603467 | Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes |
| Q34110239 | IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway |
| Q39227819 | IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways |
| Q51738202 | IL-12-mediated transcriptional regulation of matrix metalloproteinases. |
| Q33830162 | IL-1β increases asporin expression via the NF-κB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration |
| Q42054286 | IL-36α: a novel cytokine involved in the catabolic and inflammatory response in chondrocytes. |
| Q30949410 | Identification and differential expression of human collagenase-3 mRNA species derived from internal deletion, alternative splicing, and different polyadenylation and transcription initiation sites |
| Q34254458 | Identification of NURR1 as a mediator of MIF signaling during chronic arthritis: effects on glucocorticoid-induced MKP1 |
| Q37310621 | Immunomodulatory and anti-inflammatory effects of chondroitin sulphate |
| Q41871857 | Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage |
| Q34693817 | Increased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli |
| Q37616997 | Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction |
| Q35953302 | Inhibition of interleukin 1-induced matrix metalloproteinase 13 expression in human chondrocytes by interferon gamma |
| Q43992050 | Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes |
| Q36828998 | Inhibitory effect of midazolam on MMP-9, MMP-1 and MMP-13 expression in PMA-stimulated human chondrocytes via recovery of NF-κB signaling |
| Q38666235 | Interleukin-1 function and role in rheumatic disease |
| Q55480930 | Intraperitoneal injection of the SIRT1 activator SRT1720 attenuates the progression of experimental osteoarthritis in mice. |
| Q92422726 | Investigation of Cytokine Changes in Osteoarthritic Knee Joint Tissues in Response to Hyperacute Serum Treatment |
| Q39902796 | Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulum |
| Q35030282 | Knee loading reduces MMP13 activity in the mouse cartilage |
| Q35803228 | Lentivirus-induced knockdown of LRP1 induces osteoarthritic-like effects and increases susceptibility to apoptosis in chondrocytes via the nuclear factor-κB pathway |
| Q92734922 | Leonurine Exerts Anti-Catabolic and Anti-Apoptotic Effects via Nuclear Factor kappa B (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways in Chondrocytes |
| Q36113988 | Lessons from genetic forms of osteoarthritis for the pathogenesis of the disease |
| Q52657855 | Low-Intensity Pulsed Ultrasound Affects Chondrocyte Extracellular Matrix Production via an Integrin-Mediated p38 MAPK Signaling Pathway. |
| Q47389150 | Low-intensity vibration increases cartilage thickness in obese mice |
| Q24812547 | MAPK signalling in rheumatoid joint destruction: can we unravel the puzzle? |
| Q34719220 | Matrix metalloproteinase-13 downregulation and potential cartilage protective action of the Korean Red Ginseng preparation |
| Q47594163 | Metabolic responses induced by compression of chondrocytes in variable-stiffness microenvironments |
| Q35114604 | MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes. |
| Q37358880 | MicroRNA-9 regulates survival of chondroblasts and cartilage integrity by targeting protogenin |
| Q37242365 | Mitogen-activated protein kinases as therapeutic targets in osteoarthritis |
| Q92846358 | Multi-pathway Protective Effects of MicroRNAs on Human Chondrocytes in an In Vitro Model of Osteoarthritis |
| Q37701897 | NF-kappaB signaling: multiple angles to target OA. |
| Q29617726 | NF-kappaB: a key role in inflammatory diseases |
| Q91994891 | NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction |
| Q91737312 | Nanosome-Mediated Delivery Of Protein Kinase D Inhibitor Protects Chondrocytes From Interleukin-1β-Induced Stress And Apoptotic Death |
| Q42281869 | Naringenin regulates production of matrix metalloproteinases in the knee-joint and primary cultured articular chondrocytes and alleviates pain in rat osteoarthritis model |
| Q59807296 | Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes |
| Q42809042 | Negative regulation of dermal fibroblasts by enlarged adipocytes through release of free fatty acids |
| Q26860861 | Nutraceuticals: potential for chondroprotection and molecular targeting of osteoarthritis |
| Q26865318 | Osteoarthritis pathogenesis: a review of molecular mechanisms |
| Q36079468 | PEP-1-FK506BP12 inhibits matrix metalloproteinase expression in human articular chondrocytes and in a mouse carrageenan-induced arthritis model |
| Q34731316 | PKC activation induces inflammatory response and cell death in human bronchial epithelial cells |
| Q47171453 | PPAR-δ Agonist With Mesenchymal Stem Cells Induces Type II Collagen-Producing Chondrocytes in Human Arthritic Synovial Fluid |
| Q38750874 | PPAR-δ agonist with mesenchymal stem cells induces type II collagen-producing chondrocytes in human arthritic synovial fluid |
| Q37274985 | Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes |
| Q33638183 | Pentosan polysulfate inhibits IL-1β-induced iNOS, c-Jun and HIF-1α upregulation in canine articular chondrocytes |
| Q42109507 | Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes |
| Q36260387 | Pigment Epithelium-Derived Factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions. |
| Q36281858 | Platelet rich plasma (PRP) induces chondroprotection via increasing autophagy, anti-inflammatory markers, and decreasing apoptosis in human osteoarthritic cartilage. |
| Q54542310 | Polyoxypregnane glycoside from Dregea volubilis extract inhibits IL-1β-induced expression of matrix metalloproteinase via activation of NF-κB in human chondrocytes. |
| Q34149932 | Proinflammatory cytokines, prostaglandins, and the chondrocyte: mechanisms of intracellular activation |
| Q33744824 | Protective effect of Shenmai injection on knee articular cartilage of osteoarthritic rabbits and IL-1β-stimulated human chondrocytes |
| Q50872022 | Protective effects of Nebivolol against interleukin-1β (IL-1β)-induced type II collagen destruction mediated by matrix metalloproteinase-13 (MMP-13). |
| Q33991241 | Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction |
| Q37802877 | Proteomics of osteoarthritic chondrocytes and cartilage |
| Q34226676 | Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro |
| Q59330243 | Recently highlighted nutraceuticals for preventive management of osteoarthritis |
| Q52733693 | Regulation of IL-1 signaling through control of focal adhesion assembly. |
| Q21296830 | Regulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophages |
| Q35683064 | Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes |
| Q35636526 | Regulation of matrix metalloproteinases by cytokines and reactive oxygen/nitrogen species in the myocardium. |
| Q35047394 | Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA. |
| Q35783187 | RelA is required for IL-1beta stimulation of Matrix Metalloproteinase-1 expression in chondrocytes |
| Q37628401 | Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review |
| Q44607171 | Rhein inhibits interleukin-1 beta-induced activation of MEK/ERK pathway and DNA binding of NF-kappa B and AP-1 in chondrocytes cultured in hypoxia: a potential mechanism for its disease-modifying effect in osteoarthritis |
| Q89805308 | Role of Signal Transduction Pathways and Transcription Factors in Cartilage and Joint Diseases |
| Q82510584 | Role of mitogen-activated protein kinases and NFkappaB on IL-1beta-induced effects on collagen type II, MMP-1 and 13 mRNA expression in normal articular human chondrocytes |
| Q34637311 | Role of nuclear factor kappaB in synovial inflammation |
| Q37814044 | Role of proinflammatory cytokines in the pathophysiology of osteoarthritis |
| Q37609032 | Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis. |
| Q37057703 | SOCS1 suppresses IL-1β-induced C/EBPβ expression via transcriptional regulation in human chondrocytes. |
| Q38829875 | Schisandrae Fructus Inhibits IL-1β-Induced Matrix Metalloproteinases and Inflammatory Mediators Production in SW1353 Human Chondrocytes by Suppressing NF-κB and MAPK Activation |
| Q35632005 | Sclareol exerts anti-osteoarthritic activities in interleukin-1β-induced rabbit chondrocytes and a rabbit osteoarthritis model. |
| Q51141562 | Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells. |
| Q94258458 | Simvastatin prevents articular chondrocyte dedifferentiation induced by nitric oxide by inhibiting the expression of matrix metalloproteinases 1 and 13 |
| Q91876802 | Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration |
| Q36574611 | Standardized butanol fraction of WIN-34B suppresses cartilage destruction via inhibited production of matrix metalloproteinase and inflammatory mediator in osteoarthritis human cartilage explants culture and chondrocytes |
| Q34181448 | Sumoylation and Nuclear Translocation of S100A4 Regulate IL-1β-mediated Production of Matrix Metalloproteinase-13 |
| Q41623255 | Suppressive Effect of the n-Hexane Extract of Litsea japonica Fruit Flesh on Monosodium-Iodoacetate-Induced Osteoarthritis in Rats. |
| Q55176491 | Synergistic effect of maclurin on ginsenoside compound K induced inhibition of the transcriptional expression of matrix metalloproteinase-1 in HaCaT human keratinocyte cells. |
| Q40773551 | Synergistic induction of matrix metalloproteinase 1 by interleukin-1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism |
| Q42155243 | T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling |
| Q35732863 | Targeting IL-1 in inflammatory disease: new opportunities for therapeutic intervention |
| Q101216827 | Targeting miR-18a sensitizes chondrocytes to anticytokine therapy to prevent osteoarthritis progression |
| Q36701491 | Tetrandrine Inhibits the Wnt/ β -Catenin Signalling Pathway and Alleviates Osteoarthritis: An In Vitro and In Vivo Study |
| Q41900872 | The NF-kappaB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes |
| Q40014211 | The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress |
| Q40739215 | The cloning and functional analysis of canine matrix metalloproteinase-13 gene promoter |
| Q37497410 | The effects of interleukin-1β in modulating osteoclast-conditioned medium's influence on gelatinases in chondrocytes through mitogen-activated protein kinases |
| Q44525452 | The in vitro effects of dehydroepiandrosterone on human osteoarthritic chondrocytes |
| Q35840083 | The pathophysiologic role of the protein kinase Cδ pathway in the intervertebral discs of rabbits and mice: in vitro, ex vivo, and in vivo studies |
| Q36072707 | The potential of signal transduction inhibitors for the treatment of arthritis: Is it all just JNK? |
| Q64111577 | The protective effects of exenatide against AGEs-induced articular matrix degradation in human primary chondrocytes |
| Q43048764 | The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway |
| Q33614316 | The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis. |
| Q36024641 | The role of synovitis in osteoarthritis pathogenesis |
| Q34009214 | The roles of catabolic factors in the development of osteoarthritis |
| Q93166914 | Therapeutic potential of stem cell-derived extracellular vesicles in osteoarthritis: preclinical study findings |
| Q92798762 | Trans-Cinnamaldehyde Inhibits IL-1β-Stimulated Inflammation in Chondrocytes by Suppressing NF-κB and p38-JNK Pathways and Exerts Chondrocyte Protective Effects in a Rat Model of Osteoarthritis |
| Q24806147 | Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors |
| Q47243896 | Transcriptome signature identifies distinct cervical pathways induced in LPS-mediated preterm birth. |
| Q98237635 | Transglutaminase-2 regulates Wnt and FoxO3a signaling to determine the severity of osteoarthritis |
| Q35485350 | Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion. |
| Q39633554 | Unique biomaterial compositions direct bone marrow stem cells into specific chondrocytic phenotypes corresponding to the various zones of articular cartilage |
| Q37694304 | Update on Targets of Biologic Therapies for Rheumatoid Arthritis. |
| Q85572095 | WITHDRAWN: New hypothesis on the pathogenesis of osteoarthritis |
| Q29248654 | Wnt7a Inhibits IL-1β Induced Catabolic Gene Expression and Prevents Articular Cartilage Damage in Experimental Osteoarthritis |
| Q36826790 | Zoledronate upregulates MMP-9 and -13 in rat vascular smooth muscle cells by inducing oxidative stress. |
| Q36286056 | c-Jun N-Terminal Kinase in Inflammation and Rheumatic Diseases. |
| Q38315559 | c-Jun N-terminal kinase and nuclear factor κB mediate nitric oxide-induced expression of matrix metalloproteinase-13. |
| Q28343409 | c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis |
| Q37311921 | cAMP-response element-binding protein (CREB) and NF-κB transcription factors are activated during prolonged hypoxia and cooperatively regulate the induction of matrix metalloproteinase MMP1. |
| Q34088405 | p38gamma mitogen-activated protein kinase suppresses chondrocyte production of MMP-13 in response to catabolic stimulation |
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