scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0960-9822(98)70137-X |
P698 | PubMed publication ID | 9512419 |
P2093 | author name string | B B McConnell | |
G Peters | |||
S Brookes | |||
M Starborg | |||
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P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 351-354 | |
P577 | publication date | 1998-03-01 | |
P1433 | published in | Current Biology | Q1144851 |
P1476 | title | Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts | |
P478 | volume | 8 |
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Q40089139 | BS69 is involved in cellular senescence through the p53-p21Cip1 pathway. |
Q34286570 | Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts |
Q35040426 | Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein |
Q33540071 | CDK inhibition and cancer therapy |
Q88532138 | CDK inhibitors for muscle stem cell differentiation and self-renewal |
Q36532424 | CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States |
Q35118727 | Cancer and ageing: rival demons? |
Q38112116 | Cardiac stem cells in patients with heart disease |
Q39686197 | Cell cycle arrest by human cytomegalovirus 86-kDa IE2 protein resembles premature senescence |
Q35097387 | Cell senescence and hypermitogenic arrest |
Q28609756 | Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b) |
Q34903039 | Cellular senescence and organismal ageing in the absence of p21(CIP1/WAF1) in ku80(-/-) mice |
Q33953067 | Cellular senescence and protein degradation: breaking down cancer |
Q37828383 | Cellular senescence as a target in cancer control |
Q34421790 | Cellular senescence as a tumor-suppressor mechanism |
Q40266725 | Characterization of the activities of p21Cip1/Waf1 promoter-driven reporter systems during camptothecin-induced senescence-like state of BHK-21 cells |
Q41980817 | Contrasting behavior of the p18INK4c and p16INK4a tumor suppressors in both replicative and oncogene-induced senescence |
Q40533302 | Contribution of p16(INK4a) to replicative senescence of human fibroblasts |
Q24292698 | Contribution of p16INK4a and p21CIP1 pathways to induction of premature senescence of human endothelial cells: permissive role of p53 |
Q39445352 | Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis |
Q22008677 | Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest |
Q92054489 | DNA damage in human skin and the capacities of natural compounds to modulate the bystander signalling |
Q33872220 | Decreasing expression of the G1-phase inhibitors, p21Cip1 and p16INK4a, promotes division of corneal endothelial cells from older donors |
Q33957508 | Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts |
Q33638597 | Differentiation-related changes in the cell cycle traverse. |
Q38335920 | Direct control of caveolin-1 expression by FOXO transcription factors |
Q33859300 | Discovering novel chemotherapeutic drugs for the third millennium |
Q53388774 | Effects of p21 deletion in mouse models of premature aging. |
Q35680797 | Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases |
Q33855451 | Epigenetic aspects of cellular senescence |
Q24675583 | Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5 |
Q38908051 | Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence |
Q27692024 | Examination of the expanding pathways for the regulation of p21 expression and activity |
Q34025754 | Four faces of cellular senescence. |
Q34801705 | From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing |
Q30322978 | Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information. |
Q34076841 | Genes involved in senescence and immortalization |
Q53544041 | Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression. |
Q90590903 | Genistein inhibits proliferation and induces senescence in neonatal mouse pituitary gland explant cultures |
Q34982499 | Gerosuppression in confluent cells |
Q36210880 | Growth inhibition by miR-519 via multiple p21-inducing pathways |
Q40565411 | Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock |
Q42827551 | Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres |
Q39647398 | INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence |
Q28200729 | Id proteins in cell cycle control and cellular senescence |
Q40768898 | Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16(INK4a) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells. |
Q39444837 | Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes |
Q39681563 | Induction of extracellular matrix-remodeling genes by the senescence-associated protein APA-1 |
Q33958412 | Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a) |
Q39734867 | Inhibitor of differentiation 1 (ID1) promotes cell survival and proliferation of prostate epithelial cells |
Q35332453 | Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts. |
Q35918432 | Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy |
Q40738994 | Iron chelation-induced senescence-like growth arrest in hepatocyte cell lines: association of transforming growth factor beta1 (TGF-beta1)-mediated p27Kip1 expression. |
Q40881096 | LMP1 of Epstein-Barr virus suppresses cellular senescence associated with the inhibition of p16INK4a expression |
Q77614144 | Limits to lifespan |
Q40876849 | Long-term cultured IL-2-dependent T cell lines demonstrate p16(INK4a) overexpression, normal pRb/p53, and upregulation of cyclins E or D2. |
Q34250440 | Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts |
Q36557934 | Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts |
Q34056462 | MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence |
Q37113691 | Microtubule binding and disruption and induction of premature senescence by disorazole C(1). |
Q41566495 | Misidentified Human Gene Functions with Mouse Models: The Case of the Retinoblastoma Gene Family in Senescence. |
Q40901754 | Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling |
Q53632631 | Molecular signature of oncogenic ras-induced senescence. |
Q36460808 | NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation |
Q24294537 | Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts |
Q28203134 | Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence |
Q35833994 | Oxidative stress in aging human skin |
Q35201220 | PML is induced by oncogenic ras and promotes premature senescence |
Q22003910 | Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling |
Q42917409 | Real-time in vivo imaging of p16gene expression: a new approach to study senescence stress signaling in living animals |
Q33961286 | Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor |
Q34665706 | Regulation of senescence in cancer and aging |
Q35019590 | Replicative senescence and senescence-like state induced in cancer-derived cells |
Q28210023 | Repression of p15INK4b expression by Myc through association with Miz-1 |
Q35561999 | Reversal of human cellular senescence: roles of the p53 and p16 pathways |
Q40758263 | Role of cyclin-dependent kinase inhibitors in the growth arrest at senescence in human prostate epithelial and uroepithelial cells |
Q34012414 | Role of p14(ARF) in replicative and induced senescence of human fibroblasts |
Q38082328 | Senescence and aging: the critical roles of p53. |
Q35210205 | Senescence of human fibroblasts induced by oncogenic Raf. |
Q53584741 | Senescence of human skin-derived precursors regulated by Akt-FOXO3-p27(KIP¹)/p15(INK⁴b) signaling. |
Q35549516 | Smurf2-mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence |
Q43594592 | Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus. |
Q30843774 | Telomere shortening is an in vivo marker of myocyte replication and aging |
Q92783649 | The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy |
Q34966683 | The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold attachment factor B1 deficient mice |
Q33889383 | The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. |
Q28587433 | The ink4a/arf tumor suppressors cooperate with p21cip1/waf in the processes of mouse epidermal differentiation, senescence, and carcinogenesis |
Q22009397 | The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts |
Q54317457 | The p16INK4a/CDKN2A tumor suppressor and its relatives. |
Q24557451 | The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway |
Q36347895 | The retinoblastoma protein selectively represses E2F1 targets via a TAAC DNA element during cellular senescence |
Q47439670 | The role of replicative senescence in chronic allograft nephropathy. |
Q34918305 | The transcriptional cofactor MCAF1/ATF7IP is involved in histone gene expression and cellular senescence |
Q54383317 | Transcriptional activation of p21(WAF¹/CIP¹) is mediated by increased DNA binding activity and increased interaction between p53 and Sp1 via phosphorylation during replicative senescence of human embryonic fibroblasts. |
Q40887241 | Translation of p15.5INK4B, an N-terminally extended and fully active form of p15INK4B, is initiated from an upstream GUG codon |
Q35378363 | Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype |
Q24337508 | Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor |
Q33965486 | Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts |
Q49175511 | WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation |
Q35585808 | What has senescence got to do with cancer? |
Q36994782 | ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.). |
Q39325305 | ZRF1 controls oncogene-induced senescence through the INK4-ARF locus |
Q33962054 | mTOR Signaling from Cellular Senescence to Organismal Aging |
Q28115122 | miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18 |
Q73673952 | p16 INK4a can initiate an autonomous senescence program |
Q21092220 | p16(INK4a) translation suppressed by miR-24 |
Q40879237 | p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells |
Q91645670 | p53 Isoforms in Cellular Senescence- and Ageing-Associated Biological and Physiological Functions |
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