Mobile elements and disease

scientific article published on 01 June 1998

Mobile elements and disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0959-437X(98)80092-0
P698PubMed publication ID9690999

P2093author name stringH H Kazazian
P2860cites workClusters of intragenic Alu repeats predispose the human C1 inhibitor locus to deleterious rearrangementsQ24558897
The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequencesQ24606140
Structure and function of the multifunctional DNA-repair enzyme exonuclease IIIQ27730409
Human L1 retrotransposon encodes a conserved endonuclease required for retrotranspositionQ28114795
LINEs and Alus--the polyA connectionQ28116220
Cloning of the T gene required in mesoderm formation in the mouseQ28236865
A de novo Alu insertion results in neurofibromatosis type 1Q28281046
Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotranspositionQ28297748
Telomerase catalytic subunit homologs from fission yeast and humanQ29615387
Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cellsQ29617246
Reverse Transcriptase Encoded by a Human Transposable ElementQ29618213
High frequency retrotransposition in cultured mammalian cellsQ29618259
Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposonsQ30004188
Inactivation of the cholinesterase gene by Alu insertion: possible mechanism for human gene transpositionQ33240323
Translation of LINE-1 DNA elements in vitro and in human cellsQ33785234
Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposonQ33887614
Insertion of a 5' truncated L1 element into the 3' end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophyQ33897836
Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineageQ34323420
The impact of L1 retrotransposons on the human genomeQ34468340
Inactivation of muscle chloride channel by transposon insertion in myotonic miceQ34510849
Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man.Q34553577
Identification, characterization, and cell specificity of a human LINE-1 promoterQ34570051
Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNAQ35844482
Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr miceQ36129002
RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable elementQ36552964
The mouse pale ear (ep) mutation is the homologue of human Hermansky-Pudlak syndromeQ36560640
Germ line-specific expression of intracisternal A-particle retrotransposons in transgenic miceQ36561660
The decline in human Alu retroposition was accompanied by an asymmetric decrease in SRP9/14 binding to dimeric Alu RNA and increased expression of small cytoplasmic Alu RNA.Q36565648
Developmental and cell type specificity of LINE-1 expression in mouse testis: implications for transpositionQ36650559
Translation of the human LINE-1 element, L1HsQ36712171
Ribonucleoprotein particles with LINE-1 RNA in mouse embryonal carcinoma cellsQ36733242
Unit-length line-1 transcripts in human teratocarcinoma cellsQ36785924
Many human L1 elements are capable of retrotranspositionQ36859141
The molecular basis of the obese mutation in ob2J miceQ38345903
Functional differences between the human LINE retrotransposon and retroviral reverse transcriptases for in vivo mRNA reverse transcriptionQ41082589
Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell linesQ41104505
Retrotransposition of a mouse IAP sequence tagged with an indicator geneQ41699882
IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosaQ42443360
Isolation of an active human transposable elementQ42614185
An actively retrotransposing, novel subfamily of mouse L1 elementsQ42637048
Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exonQ42638958
Characterization of a nondeleterious L1 insertion in an intron of the human factor VIII gene and further evidence of open reading frames in functional L1 elementsQ42640219
The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppressionQ42658082
Origin of the human L1 elements: proposed progenitor genes deduced from a consensus DNA sequenceQ42660978
A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertionQ42693461
Identification of an Alu retrotransposition event in close proximity to a strong candidate gene for Huntington's diseaseQ45290792
Haemophilia B due to a de novo insertion of a human-specific Alu subfamily member within the coding region of the factor IX geneQ45872014
Neomorphic agouti mutations in obese yellow miceQ46156066
Ancestral, mammalian-wide subfamilies of LINE-1 repetitive sequencesQ47207133
A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetesQ48047077
Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis GeneQ48047362
The bg allele mutation is due to a LINE1 element retrotranspositionQ48049232
Mutation detection in the med and medJ alleles of the sodium channel Scn8a. Unusual splicing due to a minor class AT-AC intronQ48062096
A recombination hotspot responsible for two inherited peripheral neuropathies is located near a mariner transposon-like element.Q48066076
Mutations in the founder of the MIP gene family underlie cataract development in the mouse.Q48066771
The spastic mouse: aberrant splicing of glycine receptor beta subunit mRNA caused by intronic insertion of L1 elementQ48078656
Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion.Q48082303
Telomerase and retrotransposons: which came first?Q56902974
P433issue3
P304page(s)343-350
P577publication date1998-06-01
P1433published inCurrent Opinion in Genetics & DevelopmentQ13505684
P1476titleMobile elements and disease
P478volume8

Reverse relations

cites work (P2860)
Q402376116-alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): novel regulators of cell differentiation and proliferation
Q37218123A comprehensive analysis of recently integrated human Ta L1 elements
Q28512070A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant
Q36263207A role for endogenous reverse transcriptase in tumorigenesis and as a target in differentiating cancer therapy.
Q24656941Aberrant caspase-activated DNase (CAD) transcripts in human hepatoma cells
Q36729306Active transposition in genomes
Q34141813Additional copies of the proteolipid protein gene causing Pelizaeus-Merzbacher disease arise by separate integration into the X chromosome
Q24675735All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition
Q35549613Alu pair exclusions in the human genome
Q24555185Alu-mediated inactivation of the human CMP- N-acetylneuraminic acid hydroxylase gene
Q77883168An estimated frequency of endogenous insertional mutations in humans
Q24550997Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes
Q35650901Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells
Q84782218Bioinformatic analysis of TE-spliced new exons within human, mouse and zebrafish genomes
Q37293212Characterization and distribution of retrotransposons and simple sequence repeats in the bovine genome
Q34092186Comparative genomics of the human and mouse T cell receptor loci
Q23067954Demystified. Human endogenous retroviruses
Q39586006Determination of L1 retrotransposition kinetics in cultured cells
Q42618146Different rates of LINE-1 (L1) retrotransposon amplification and evolution in New World monkeys.
Q39072419Differential L1 regulation in pluripotent stem cells of humans and apes.
Q36331117Distribution of a marker of germline methylation differs between major families of transposon-derived repeats in the human genome
Q37379454Environmental influence on L1 retrotransposons in the adult hippocampus
Q36163349Epigenetic control of mammalian LINE-1 retrotransposon by retinoblastoma proteins.
Q40662096Functional reverse transcriptase encoded by the human LINE-1 from baculovirus-infected insect cells
Q25255521Gamma radiation increases endonuclease-dependent L1 retrotransposition in a cultured cell assay
Q22122336Genetics: Junk DNA as an evolutionary force
Q30650874Genomic scrap yard: how genomes utilize all that junk
Q33266809Global mapping of transposon location
Q52940179Growth and decline of introns.
Q33259824Heat-shock promoters: targets for evolution by P transposable elements in Drosophila
Q37271908Heavy metals stimulate human LINE-1 retrotransposition
Q34363582Hierarchical assembly of the Alu domain of the mammalian signal recognition particle
Q35751107Host RNAs, including transposons, are encapsidated by a eukaryotic single-stranded RNA virus
Q42095539How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts
Q73134117Human endogenous retroviruses and pathogenicity: genomic considerations
Q56589628Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue
Q37415872Identification of Cryptic Novel α-Galactosidase A Gene Mutations: Abnormal mRNA Splicing and Large Deletions
Q42990988Identification, characterization and comparative genomics of chimpanzee endogenous retroviruses
Q37738649Insertion Polymorphisms of Mobile Genetic Elements in Sexual and Asexual Populations of Daphnia pulex
Q29615764Interspersed repeats and other mementos of transposable elements in mammalian genomes
Q33703747Ionizing radiation and genetic risks. X. The potential "disease phenotypes" of radiation-induced genetic damage in humans: perspectives from human molecular biology and radiation genetics
Q37139954L1 mobile element expression causes multiple types of toxicity.
Q34686579L1 retrotransposition in neurons is modulated by MeCP2
Q33245909LINE FUSION GENES: a database of LINE expression in human genes
Q33211669LINE-1 amplification accompanies explosive genome repatterning in rodents
Q40520772LINE-1 distribution in Afrotheria and Xenarthra: implications for understanding the evolution of LINE-1 in eutherian genomes.
Q40670348LINE-1 preTa elements in the human genome.
Q28584519LINEs between Species: Evolutionary Dynamics of LINE-1 Retrotransposons across the Eukaryotic Tree of Life
Q61658996Local Mutagenic Impact of Insertions of LTR Retrotransposons on the Mouse Genome
Q36181065Long terminal repeat retrotransposons jump between species
Q28469078Mammalian small nucleolar RNAs are mobile genetic elements
Q36224644MeCP2 as a genome-wide modulator: the renewal of an old story
Q35047364Mobile genetic elements in protozoan parasites
Q30428528Mobilomics in Saccharomyces cerevisiae strains
Q24817207Modeling the amplification dynamics of human Alu retrotransposons
Q44119468Molecular characterization of a 2.7-kb, 12q13-specific, retroviral-related sequence isolated by RDA from monozygotic twin pairs discordant for schizophrenia
Q28748621Nickel stimulates L1 retrotransposition by a post-transcriptional mechanism
Q41110305PoPoolationTE2: Comparative Population Genomics of Transposable Elements Using Pool-Seq.
Q42610891Quantitative variation of LINE-1 sequences in five species and three subspecies of the subgenus Mus and in five Robertsonian races of Mus musculus domesticus.
Q33780174RISCI--Repeat Induced Sequence Changes Identifier: a comprehensive, comparative genomics-based, in silico subtractive hybridization pipeline to identify repeat induced sequence changes in closely related genomes
Q42597900Redox Regulation of a Novel L1Md-A2 Retrotransposon in Vascular Smooth Muscle Cells
Q92150005Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes
Q24805857Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intactp53
Q34007948Retrotransposon-centered analysis of piRNA targeting shows a shift from active to passive retrotransposon transcription in developing mouse testes
Q34042729Retrotransposon-induced heterochromatin spreading in the mouse revealed by insertional polymorphisms
Q73695300Retrotransposons as epigenetic mediators of phenotypic variation in mammals
Q25255710Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line
Q33963329SINE retroposons can be used in vivo as nucleation centers for de novo methylation
Q31008741Specific localization of transcription factors in the chromatin of mouse mature spermatozoa.
Q27628611Structure and assembly of the Alu domain of the mammalian signal recognition particle
Q36541045Structure and expression of mobile ETnII retroelements and their coding-competent MusD relatives in the mouse
Q42271884Structure of the complete bacterial SRP Alu domain
Q30821572TE-Locate: A Tool to Locate and Group Transposable Element Occurrences Using Paired-End Next-Generation Sequencing Data
Q33851829The biological properties and evolutionary dynamics of mammalian LINE-1 retrotransposons
Q44404819The endonuclease NL1Tc encoded by the LINE L1Tc from Trypanosoma cruzi protects parasites from daunorubicin DNA damage.
Q34570688The first steps of transposable elements invasion: parasitic strategy vs. genetic drift
Q34526958The genetics of the target tissue in rheumatoid arthritis
Q44012138The non-LTR (long terminal repeat) retrotransposon L1Tc from Trypanosoma cruzi codes for a protein with RNase H activity.
Q33724325The pathogenic potential of endogenous retroviruses: facts and fantasies
Q35016886The potential regulation of L1 mobility by RNA interference.
Q33204795The repetitive landscape of the chicken genome
Q34762192Tracking an embryonic L1 retrotransposition event
Q39611509Transcriptional regulation of early transposon elements, an active family of mouse long terminal repeat retrotransposons
Q36901962Transcriptomics analysis of iPSC-derived neurons and modeling of neuropsychiatric disorders.
Q44019080Transfer RNA gene-targeted retrotransposition of Dictyostelium TRE5-A into a chromosomal UMP synthase gene trap
Q28710587Transposable elements and viruses as factors in adaptation and evolution: an expansion and strengthening of the TE-Thrust hypothesis
Q53867468Unusual expression of LINE-1 transposable element in the MRL autoimmune lymphoproliferative syndrome-prone strain.
Q52596587Utilization of the IR hybrid dysgenesis system in Drosophila to test in vivo mobilization of synthetic SINEs sharing 3' homology with the I factor.
Q27013917Viral quasispecies evolution
Q48396756Yayoi era mutation disrupts brain and muscle

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