L1 mobile element expression causes multiple types of toxicity.

scientific article published on 03 May 2008

L1 mobile element expression causes multiple types of toxicity. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.GENE.2008.04.013
P932PMC publication ID3760205
P698PubMed publication ID18555620
P5875ResearchGate publication ID5300381

P50authorPrescott DeiningerQ42533877
P2093author name stringVictoria P Belancio
Nicholas A Wallace
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intactp53Q24805857
Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineagesQ24813998
Human L1 retrotransposon encodes a conserved endonuclease required for retrotranspositionQ28114795
APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanismQ28237264
A concise review of DNA damage checkpoints and repair in mammalian cellsQ28261168
Cell-cycle checkpoints and cancerQ28293996
Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotranspositionQ28297748
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3LQ28585211
Mobile elements: drivers of genome evolutionQ29547669
ATM and related protein kinases: safeguarding genome integrityQ29547735
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesisQ29614217
Reverse Transcriptase Encoded by a Human Transposable ElementQ29618213
High frequency retrotransposition in cultured mammalian cellsQ29618259
Human L1 retrotransposition: cis preference versus trans complementationQ29618363
Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposonsQ30004188
Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.Q30445599
Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposonQ33887614
Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis.Q33927698
Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cellsQ33995584
The human LINE-1 retrotransposon creates DNA double-strand breaks.Q34061457
53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancerQ34160527
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damageQ34179079
Human L1 element target-primed reverse transcription in vitroQ34207225
LINE-1 RNA splicing and influences on mammalian gene expressionQ34483165
APOBEC3 proteins inhibit human LINE-1 retrotranspositionQ34532057
L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cellsQ34561057
L1 retrotransposition in nondividing and primary human somatic cellsQ34650044
DNA damage checkpoint kinase Chk2 triggers replicative senescenceQ35835972
Endonuclease-independent insertion provides an alternative pathway for L1 retrotransposition in the human genomeQ35893869
The cellular response to chromosome breakage.Q36475466
BCL2 family in DNA damage and cell cycle controlQ36501194
RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable elementQ36552964
In vitro properties of the first ORF protein from mouse LINE-1 support its role in ribonucleoprotein particle formation during retrotranspositionQ36583469
Many human L1 elements are capable of retrotranspositionQ36859141
High-affinity, non-sequence-specific RNA binding by the open reading frame 1 (ORF1) protein from long interspersed nuclear element 1 (LINE-1).Q38359167
Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE-1 retrotransposonQ39457323
Macrophages but not smooth muscle cells undergo benzyloxycarbonyl-Val-Ala-DL-Asp(O-Methyl)-fluoromethylketone-induced nonapoptotic cell death depending on receptor-interacting protein 1 expression: implications for the stabilization of macrophage-riQ40304808
Twin priming: a proposed mechanism for the creation of inversions in L1 retrotranspositionQ40415833
Ligation of CD40 rescues Ramos-Burkitt lymphoma B cells from calcium ionophore- and antigen receptor-triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARP.Q41198087
Proteases in apoptosisQ41211009
RNA truncation by premature polyadenylation attenuates human mobile element activityQ42833909
Analysis of 5' junctions of human LINE-1 and Alu retrotransposons suggests an alternative model for 5'-end attachment requiring microhomology-mediated end-joiningQ42844670
Oestrogen-mediated suppression of tumour necrosis factor alpha-induced apoptosis in MCF-7 cells: subversion of Bcl-2 by anti-oestrogensQ43819124
Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemiaQ44500993
A potential role for the nucleolus in L1 retrotranspositionQ44804000
DNA repair mediated by endonuclease-independent LINE-1 retrotranspositionQ48304886
Alu-linked hairpins efficiently mediate RNA interference with less toxicity than do H1-expressed short hairpin RNAs.Q50745091
L1 retrotransposition can occur early in human embryonic development.Q51986818
Genomic deletions created upon LINE-1 retrotranspositionQ74604693
Mobile elements and diseaseQ74837228
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)75-81
P577publication date2008-05-03
P1433published inGeneQ5531065
P1476titleL1 mobile element expression causes multiple types of toxicity
P478volume419

Reverse relations

cites work (P2860)
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