scholarly article | Q13442814 |
P50 | author | Prescott Deininger | Q42533877 |
P2093 | author name string | Victoria P Belancio | |
Nicholas A Wallace | |||
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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis | Q29614217 | ||
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The human LINE-1 retrotransposon creates DNA double-strand breaks. | Q34061457 | ||
53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer | Q34160527 | ||
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Human L1 element target-primed reverse transcription in vitro | Q34207225 | ||
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APOBEC3 proteins inhibit human LINE-1 retrotransposition | Q34532057 | ||
L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells | Q34561057 | ||
L1 retrotransposition in nondividing and primary human somatic cells | Q34650044 | ||
DNA damage checkpoint kinase Chk2 triggers replicative senescence | Q35835972 | ||
Endonuclease-independent insertion provides an alternative pathway for L1 retrotransposition in the human genome | Q35893869 | ||
The cellular response to chromosome breakage. | Q36475466 | ||
BCL2 family in DNA damage and cell cycle control | Q36501194 | ||
RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable element | Q36552964 | ||
In vitro properties of the first ORF protein from mouse LINE-1 support its role in ribonucleoprotein particle formation during retrotransposition | Q36583469 | ||
Many human L1 elements are capable of retrotransposition | Q36859141 | ||
High-affinity, non-sequence-specific RNA binding by the open reading frame 1 (ORF1) protein from long interspersed nuclear element 1 (LINE-1). | Q38359167 | ||
Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE-1 retrotransposon | Q39457323 | ||
Macrophages but not smooth muscle cells undergo benzyloxycarbonyl-Val-Ala-DL-Asp(O-Methyl)-fluoromethylketone-induced nonapoptotic cell death depending on receptor-interacting protein 1 expression: implications for the stabilization of macrophage-ri | Q40304808 | ||
Twin priming: a proposed mechanism for the creation of inversions in L1 retrotransposition | Q40415833 | ||
Ligation of CD40 rescues Ramos-Burkitt lymphoma B cells from calcium ionophore- and antigen receptor-triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARP. | Q41198087 | ||
Proteases in apoptosis | Q41211009 | ||
RNA truncation by premature polyadenylation attenuates human mobile element activity | Q42833909 | ||
Analysis of 5' junctions of human LINE-1 and Alu retrotransposons suggests an alternative model for 5'-end attachment requiring microhomology-mediated end-joining | Q42844670 | ||
Oestrogen-mediated suppression of tumour necrosis factor alpha-induced apoptosis in MCF-7 cells: subversion of Bcl-2 by anti-oestrogens | Q43819124 | ||
Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia | Q44500993 | ||
A potential role for the nucleolus in L1 retrotransposition | Q44804000 | ||
DNA repair mediated by endonuclease-independent LINE-1 retrotransposition | Q48304886 | ||
Alu-linked hairpins efficiently mediate RNA interference with less toxicity than do H1-expressed short hairpin RNAs. | Q50745091 | ||
L1 retrotransposition can occur early in human embryonic development. | Q51986818 | ||
Genomic deletions created upon LINE-1 retrotransposition | Q74604693 | ||
Mobile elements and disease | Q74837228 | ||
P433 | issue | 1-2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 75-81 | |
P577 | publication date | 2008-05-03 | |
P1433 | published in | Gene | Q5531065 |
P1476 | title | L1 mobile element expression causes multiple types of toxicity | |
P478 | volume | 419 |
Q33872587 | A LINE-1 component to human aging: do LINE elements exact a longevity cost for evolutionary advantage? |
Q92819740 | A potential new mechanism for pregnancy loss: considering the role of LINE-1 retrotransposons in early spontaneous miscarriage |
Q33751005 | A role for retrotransposon LINE-1 in fetal oocyte attrition in mice |
Q37533731 | A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan |
Q56765662 | Activity of Retrotransposons in Stem Cells and Differentiated Cells |
Q34143181 | All y'all need to know 'bout retroelements in cancer. |
Q34643317 | An S/MAR-based L1 retrotransposition cassette mediates sustained levels of insertional mutagenesis without suffering from epigenetic silencing of DNA methylation |
Q35650901 | Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells |
Q28396772 | Biomarkers of lead exposure and DNA methylation within retrotransposons |
Q89637752 | Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication |
Q28742355 | Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs |
Q36435097 | Circular retrotransposition products generated by a LINE retrotransposon |
Q60143966 | Contribution of Retrotransposable Elements to Aging |
Q37727855 | Cross-Regulation between Transposable Elements and Host DNA Replication |
Q64113810 | Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming |
Q36782347 | Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation |
Q35097642 | Environmental epigenetics |
Q43980375 | Epigenetic marker (LINE-1 promoter) methylation level was associated with occupational lead exposure |
Q47386205 | Evaluating different DNA binding domains to modulate L1 ORF2p-driven site-specific retrotransposition events in human cells. |
Q38988524 | Evaluating the extent of LINE-1 mobility following exposure to heavy metals in HepG2 cells. |
Q33900194 | Evolutionary conservation of the functional modularity of primate and murine LINE-1 elements |
Q34746787 | Expression of a LINE-1 endonuclease variant in gastric cancer: its association with clinicopathological parameters |
Q38273264 | Feedback inhibition of L1 and alu retrotransposition through altered double strand break repair kinetics. |
Q28589716 | GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline |
Q36745810 | Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements |
Q50285641 | Global Level of Plasma DNA Methylation is Associated with Overall Survival in Patients with Hepatocellular Carcinoma |
Q41838838 | HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition. |
Q36959087 | Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR). |
Q39740145 | Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F. |
Q33913579 | Intact piRNA pathway prevents L1 mobilization in male meiosis |
Q33552542 | Integrated approach of nutritional and molecular epidemiology, mineralogical and chemical pollutant characterisation: the protocol of a cross-sectional study in women |
Q37442539 | Internal priming: an opportunistic pathway for L1 and Alu retrotransposition in hominins |
Q39013867 | Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition |
Q35687914 | L1 expression and regulation in humans and rodents |
Q55692166 | L1 retrotransposition in the soma: a field jumping ahead. |
Q37442902 | LINE dancing in the human genome: transposable elements and disease |
Q92358546 | LINE-1 ORF2p expression is nearly imperceptible in human cancers |
Q46544707 | LINE-1 Retrotransposons in Healthy and Diseased Human Brain |
Q37028334 | LINE-1 and Alu retrotransposition exhibit clonal variation |
Q34468156 | LINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines. |
Q46854804 | LINE-1 retrotransposons: from 'parasite' sequences to functional elements |
Q28729045 | LINEs, SINEs and other retroelements: do birds of a feather flock together? |
Q34337046 | Long interspersed element-1 (LINE-1): passenger or driver in human neoplasms? |
Q37734876 | Long interspersed element-1 protein expression is a hallmark of many human cancers |
Q35858857 | Low fruit consumption and folate deficiency are associated with LINE-1 hypomethylation in women of a cancer-free population |
Q36000665 | Male germline control of transposable elements |
Q92711483 | Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity |
Q35069309 | Methylation levels of the "long interspersed nucleotide element-1" repetitive sequences predict survival of melanoma patients |
Q36158723 | Neurotoxic Methamphetamine Doses Increase LINE-1 Expression in the Neurogenic Zones of the Adult Rat Brain |
Q33898508 | Non-long terminal repeat (non-LTR) retrotransposons: mechanisms, recent developments, and unanswered questions |
Q34602255 | PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos |
Q26750825 | Post-Transcriptional Control of LINE-1 Retrotransposition by Cellular Host Factors in Somatic Cells |
Q34249538 | Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci |
Q27312622 | Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability |
Q60044601 | Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis |
Q28241693 | Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night |
Q35605212 | Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility |
Q35611983 | Restless genomes humans as a model organism for understanding host-retrotransposable element dynamics |
Q36310409 | Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS |
Q22252317 | Retrotransposons Revisited: The Restraint and Rehabilitation of Parasites |
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Q38822875 | Senescence Meets Dedifferentiation |
Q33959421 | Somatic expression of LINE-1 elements in human tissues. |
Q47333028 | Spontaneous death of rat chloroleukaemia cells induced by an endogenous growth inhibitor |
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Q38359533 | The Roles of the Stem Cell-Controlling Sox2 Transcription Factor: from Neuroectoderm Development to Alzheimer's Disease? |
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