Alteration of the PTEN/MMAC1 gene locus in primary lung cancer with distant metastasis

scientific article published on 01 August 1999

Alteration of the PTEN/MMAC1 gene locus in primary lung cancer with distant metastasis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0169-5002(99)00052-5
P698PubMed publication ID10470842

P2093author name stringM Shibuya
A Yoshimura
A Gemma
M Seike
S Kudoh
S Hibino
K Uematsu
Y Hosoya
F Kurimoto
P2860cites workP-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancersQ28251857
A cell cycle regulator potentially involved in genesis of many tumor typesQ28251933
Mutation analysis of the PTEN/MMAC1 gene in lung cancerQ28287144
p53 mutations in human cancersQ28302973
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersQ28306997
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndromeQ29615538
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.Q33825340
Mutations and altered expression of p16INK4 in human cancer.Q35892778
Molecular analysis of the cyclin-dependent kinase inhibitor genes p15INK4b/MTS2, p16INK4/MTS1, p18 and p19 in human cancer cell linesQ41149955
Allelic loss on chromosome 10q in human lung cancer: association with tumour progression and metastatic phenotypeQ42860747
PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancersQ47720095
Distinct regions of allelic imbalance on chromosome 10q22-q26 in squamous cell carcinomas of the lungQ47720136
hSmad5 gene, a human hSmad family member: its full length cDNA, genomic structure, promoter region and mutation analysis in human tumorsQ48040026
Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancersQ48464018
Stability of p53 tumor suppressor gene mutations during the process of metastasis and during chemotherapyQ71505748
Allelic losses at loci on chromosome 10 are associated with metastasis and progression of human prostate cancerQ71839777
P433issue2
P304page(s)87-93
P577publication date1999-08-01
P1433published inLung CancerQ641464
P1476titleAlteration of the PTEN/MMAC1 gene locus in primary lung cancer with distant metastasis
P478volume25

Reverse relations

cites work (P2860)
Q46710025Coalterations of p53 and PTEN tumor suppressor genes in non-small cell lung carcinoma patients
Q37354026Dysregulation of mTOR activity through LKB1 inactivation
Q33265628Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulation
Q25257717Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies
Q34254614Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas
Q90376926Overview upon miR-21 in lung cancer: focus on NSCLC
Q36506366PTEN encoding product: a marker for tumorigenesis and progression of gastric carcinoma
Q35504084Phosphatases: the new brakes for cancer development?
Q54182757Prolonged survival after neoadjuvant chemotherapy related with specific molecular alterations in the patients with nonsmall-cell lung carcinoma.
Q36929407Recent progress in mouse models for tumor suppressor genes and its implications in human cancer
Q40426911Reduction of PTEN protein and loss of epidermal growth factor receptor gene mutation in lung cancer with natural resistance to gefitinib (IRESSA).