Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response

scientific article published on 26 May 2007

Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1039736767
P356DOI10.1007/S00109-007-0191-4
P698PubMed publication ID17530208

P50authorJuha PalonevaQ55690490
Dimitri HemelsoetQ63676466
P2093author name stringLeena Peltonen
Ilkka Julkunen
Juha Saharinen
Anna Kiialainen
Outi Kopra
Massimiliano Gentile
Ville Veckman
Panu Hakola
Basil Ridha
P2860cites workCutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytesQ22254042
Gene ontology: tool for the unification of biologyQ23781406
A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cellsQ24291798
Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cellsQ24315619
Toll-like receptor signallingQ24570126
Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotypeQ24611595
DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic featuresQ24672682
Impaired differentiation of osteoclasts in TREM-2-deficient individualsQ24672735
Iterative Group Analysis (iGA): a simple tool to enhance sensitivity and facilitate interpretation of microarray experimentsQ24796175
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchiesQ24801173
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating diseaseQ28207482
Differential interaction of Crkl with Cbl or C3G, Hef-1, and gamma subunit immunoreceptor tyrosine-based activation motif in signaling of myeloid high affinity Fc receptor for IgG (Fc gamma RI)Q28289106
DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinaseQ28610866
An overview of EnsemblQ29615978
The IkappaB-NF-kappaB signaling module: temporal control and selective gene activationQ29617813
DAP12: a key accessory protein for relaying signals by natural killer cell receptorsQ33686435
Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.Q33908939
The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell functionQ34103308
Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa BQ34305414
The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2.Q36121607
DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitisQ36403308
Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microgliaQ37088528
Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.Q39669362
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.Q42057034
Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementiaQ44253971
DAP12-deficient mice fail to develop autoimmunity due to impaired antigen primingQ46091534
Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice.Q46460939
IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 moleculesQ47644573
Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesionsQ47969472
A lipid metabolic disease-"membranous lipodystrophy"-an autopsy case demonstrating numerous peculiar membrane-structures composed of compound lipid in bone and bone marrow and various adipose tissuesQ48638415
Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's diseaseQ48690661
Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1-type cytokines and chemokines in human monocyte-derived dendritic cells.Q51035102
Dap12 and Trem2, molecules involved in innate immunity and neurodegeneration, are co-expressed in the CNS.Q52058734
Neuropsychiatric and genetic aspects of a new hereditary disease characterized by progressive dementia and lipomembranous polycystic osteodysplasiaQ52121461
Adenoviral down-regulation of osteopontin inhibits human osteoclast differentiation in vitroQ57533584
Fascin is involved in the antigen presentation activity of mature dendritic cellsQ73311874
Intrathecal synthesis of monocyte chemoattractant protein-1 (MCP-1) in amyotrophic lateral sclerosis: further evidence for microglial activation in neurodegenerationQ79247063
P433issue9
P921main subjectdendritic cellQ506253
P304page(s)971-983
P577publication date2007-05-26
P1433published inJournal of Molecular MedicineQ6295593
P1476titleTranscript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response
P478volume85

Reverse relations

cites work (P2860)
Q92974056A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2
Q37200594Critical immunological pathways are downregulated in APECED patient dendritic cells
Q41845995Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease
Q33999537Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease
Q37347848Epigenomic profiling of preterm infants reveals DNA methylation differences at sites associated with neural function
Q27303397Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).
Q28472357Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity
Q28508939Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity
Q38646212TREM2 in Neurodegenerative Diseases
Q57418361Triggering receptor expressed on myeloid cells 2 (TREM2): a potential therapeutic target for Alzheimer disease?
Q36744437Word list learning in patients with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy

Search more.