Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation

scientific article published on 16 January 2008

Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1051321377
P356DOI10.1007/S11011-007-9074-1
P698PubMed publication ID18197471

P50authorH Y L TungQ80497743
Hugh C HemmingsQ87850191
Paul M. HeerdtQ91472618
P2093author name stringJimcy Platholi
Tao T Zhang
P2860cites workProtein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingQ24532278
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Ischemic cell death in brain neuronsQ28145434
The protein phosphatases involved in cellular regulation. 6. Measurement of type-1 and type-2 protein phosphatases in extracts of mammalian tissues; an assessment of their physiological rolesQ28265291
Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vprQ28302512
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonineQ28643999
The structure and regulation of protein phosphatasesQ29618929
Cerebral ischaemia in experimental cardiopulmonary resuscitation--comparison of epinephrine and aortic occlusionQ30767770
Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociationQ32061766
The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondriaQ33292529
Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamateQ34054189
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Excitotoxic cell deathQ34245367
Excitatory amino acids as a final common pathway for neurologic disorders.Q34321926
Serine/threonine protein phosphatases in apoptosisQ34750493
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Phosphatases in apoptosis: to be or not to be, PP2A is in the heart of the questionQ35120898
Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosisQ35571485
Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A.Q35614264
Myocardial ischemia: the pathogenesis of irreversible cell injury in ischemiaQ35863648
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Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitroQ40485088
Mechanisms of cerebral ischemia: intracellular cascades and therapeutic interventionsQ40988746
Global forebrain ischemia induces a posttranslational modification of multifunctional calcium- and calmodulin-dependent kinase IIQ41086082
Intracellular signal transduction in the postischemic brainQ41099117
Neurological outcome after experimental cardiopulmonary resuscitation: a result of delayed and potentially treatable neuronal injury?Q44004359
Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130.Q44350742
Erasure of kinase phosphorylation in astrocytes during oxygen-glucose deprivation is controlled by ATP levels and activation of phosphatases.Q44545161
Protein kinase C delta mediates cerebral reperfusion injury in vivo.Q45937676
Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injuryQ48244677
Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic toleranceQ48278407
Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosisQ48427213
Identification and characterization of an ATP.Mg-dependent protein phosphatase from pig brainQ48436789
Ischemia-induced translocation of Ca2+/calmodulin-dependent protein kinase II: potential role in neuronal damageQ48491044
Cerebral postischemic reperfusion-induced demethylation of the protein phosphatase 2A catalytic subunitQ48494123
Ischemia-induced inhibition of the initiation factor 2alpha phosphatase activity in the rat brainQ48917020
Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2+/calmodulin-dependent protein kinase in a canine cardiac arrest model.Q51374695
A novel protein phosphatase inhibitor, tautomycin. Effect on smooth muscle.Q53858292
The protein phosphatases involved in cellular regulation. 1. Classification and substrate specificities.Q55062472
Subcellular distribution and autophosphorylation of calcium/calmodulin-dependent protein kinase II-α in rat hippocampus in a model of ischemic toleranceQ60597094
Persistent Translocation of Ca2+/Calmodulin-Dependent Protein Kinase II to Synaptic Junctions in the Vulnerable Hippocampal CA1 Region Following Transient IschemiaQ60597166
Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscleQ69836001
Purification and characterization of protein phosphatase 1I activating kinase from bovine brain cytosolic and particulate fractionsQ69942830
The protein phosphatases involved in cellular regulation. 2. Purification, subunit structure and properties of protein phosphatases-2A0, 2A1, and 2A2 from rabbit skeletal muscleQ70082819
Mechanisms of ischemic brain damageQ70214064
Glutamate, calcium, and free radicals as mediators of ischemic brain damageQ72200300
P433issue1
P921main subjectcardiac arrestQ202837
resuscitationQ5491454
P304page(s)95-104
P577publication date2008-01-16
P1433published inMetabolic Brain DiseaseQ15764352
P1476titleProtein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation
P478volume23

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cites work (P2860)
Q33971251Activation of protein kinase C delta following cerebral ischemia leads to release of cytochrome C from the mitochondria via bad pathway
Q34130984Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia

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