Antibodies and vaccines against Middle East respiratory syndrome coronavirus

scientific article published in 2019

Antibodies and vaccines against Middle East respiratory syndrome coronavirus is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1080/22221751.2019.1624482
P932PMC publication ID6567157
P698PubMed publication ID31169078

P50authorJiuyang XuQ64878619
Xinquan WangQ90294415
Linqi ZhangQ91516083
P2093author name stringPengfei Wang
Xuanling Shi
Senyan Zhang
Wenxu Jia
P2860cites workOrigin and evolution of pathogenic coronavirusesQ87747946
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Structure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome CoronavirusQ27680061
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Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies.Q30362113
Tailoring subunit vaccine immunity with adjuvant combinations and delivery routes using the Middle East respiratory coronavirus (MERS-CoV) receptor-binding domain as an antigen.Q30368736
Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus.Q30371303
A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform.Q30378994
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Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infectionQ30399700
DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in miceQ30400066
Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome CoronavirusQ30400728
A novel neutralizing monoclonal antibody targeting the N-terminal domain of the MERS-CoV spike proteinQ30402347
Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domainsQ30845557
Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolutionQ33627189
A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein.Q33743790
The spike protein of SARS-CoV--a target for vaccine and therapeutic developmentQ34015988
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Rooting the phylogenetic tree of middle East respiratory syndrome coronavirus by characterization of a conspecific virus from an African batQ34261861
Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments--the importance of immunofocusing in subunit vaccine designQ34324907
The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodiesQ34653419
Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formationQ35009468
A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccinesQ35063993
Receptor recognition mechanisms of coronaviruses: a decade of structural studiesQ35115572
Heterologous prime-boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory syndrome coronavirus.Q54217812
Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus.Q54241763
International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trialsQ56447686
Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infectionQ56558457
Prophylactic and therapeutic efficacy of mAb treatment against MERS-CoV in common marmosetsQ56907500
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysisQ57794680
A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoVQ58693121
Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2Q58785257
Live-attenuated bivalent measles virus-derived vaccines targeting Middle East respiratory syndrome coronavirus induce robust and multifunctional T cell responses against both viruses in an appropriate mouse modelQ59358732
Combining a Fusion Inhibitory Peptide Targeting the MERS-CoV S2 Protein HR1 Domain and a Neutralizing Antibody Specific for the S1 Protein Receptor-Binding Domain (RBD) Showed Potent Synergism against Pseudotyped MERS-CoV with or without Mutations inQ61805218
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spikeQ63246151
A novel human mAb (MERS-GD27) provides prophylactic and postexposure efficacy in MERS-CoV susceptible miceQ64136721
Ultrapotent Human Neutralizing Antibody Repertoires Against Middle East Respiratory Syndrome Coronavirus From a Recovered PatientQ64137589
Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infectionQ64374628
A highly immunogenic, protective and safe adenovirus-based vaccine expressing MERS-CoV S1-CD40L fusion protein in transgenic human DPP4 mouse modelQ64374803
Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoproteinQ35159147
Effect of preexisting immunity to adenovirus human serotype 5 antigens on the immune responses of nonhuman primates to vaccine regimens based on human- or chimpanzee-derived adenovirus vectorsQ35857215
Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infectionQ35865538
Optimization of antigen dose for a receptor-binding domain-based subunit vaccine against MERS coronavirusQ35887626
Evaluation of candidate vaccine approaches for MERS-CoV.Q35917397
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Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirusQ35989939
Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody.Q36063562
A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primatesQ36069589
Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus ChallengeQ36252666
Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humansQ36432023
Recovery in tracheal organ cultures of novel viruses from patients with respiratory diseaseQ36465731
Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4.Q36562859
3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012Q36626864
Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)-Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV InfectionQ36816625
Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus InfectionQ37188934
Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virusQ37264927
One-Health: a Safe, Efficient, Dual-Use Vaccine for Humans and Animals against Middle East Respiratory Syndrome Coronavirus and Rabies VirusQ37560824
MERS-CoV virus-like particles produced in insect cells induce specific humoural and cellular imminity in rhesus macaquesQ37706472
The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infectionQ39144823
Replication-defective vector based on a chimpanzee adenovirusQ39605384
Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infectionQ39677274
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.Q40083207
ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in miceQ40173497
Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset.Q40215096
Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.Q40252744
MERS-CoV spike nanoparticles protect mice from MERS-CoV infectionQ40317741
Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor bindingQ40397876
A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infectionQ40503787
Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in miceQ40744757
An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camelsQ40867301
Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike GlycoproteinQ41199088
Systemic and mucosal immunity in mice elicited by a single immunization with human adenovirus type 5 or 41 vector-based vaccines carrying the spike protein of Middle East respiratory syndrome coronavirusQ41242033
Immunogenicity of an adenoviral-based Middle East Respiratory Syndrome coronavirus vaccine in BALB/c miceQ41752133
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.Q42152380
Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virus-neutralizing antibodiesQ42249511
Origins and pathogenesis of Middle East respiratory syndrome-associated coronavirus: recent advancesQ42353676
Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003.Q42612038
A new virus isolated from the human respiratory tractQ45825116
Protective efficacy of a novel simian adenovirus vaccine against lethal MERS-CoV challenge in a transgenic human DPP4 mouse modelQ47147430
A recombinant VSV-vectored MERS-CoV vaccine induces neutralizing antibody and T cell responses in rhesus monkeys after single dose immunizationQ47288304
Middle East respiratory syndrome.Q51011540
Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on MERS-CoV Spike to avoid neutralization escape.Q51149122
Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome.Q51660929
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectviral antibodiesQ66021534
betacoronaviruses spike proteinQ81490886
CoronavirusQ290805
monoclonal antibodyQ422248
Middle East respiratory syndromeQ16654806
RNA virus infectious diseaseQ18967413
coronavirus diseaseQ18975243
P304page(s)841-856
P577publication date2019-01-01
P1433published inEmerging Microbes & InfectionsQ27724513
P1476titleAntibodies and vaccines against Middle East respiratory syndrome coronavirus
P478volume8

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cites work (P2860)
Q905504282019 novel Coronavirus outbreak: a quiz or final exam?
Q84316056Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein
Q90425437COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics
Q90744942COVID-19: what has been learned and to be learned about the novel coronavirus disease
Q89879578Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development
Q95851279Human neutralizing antibodies elicited by SARS-CoV-2 infection
Q87461749Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China
Q99240136Nanomedicine strategies to target coronavirus
Q90658009Pharmacologic Treatments and Supportive Care for Middle East Respiratory Syndrome
Q95262934Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cells
Q94545219The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses
Q95933666Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

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