| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/978-1-4419-6706-0_2 |
| P953 | full work available at URL | http://link.springer.com/content/pdf/10.1007/978-1-4419-6706-0_2.pdf |
| P698 | PubMed publication ID | 20919636 |
| P50 | author | Diego Rojas-Rivera | Q79257563 |
| P2093 | author name string | Claudio Hetz | |
| Benjamin Caballero | |||
| Fernanda Lisbona | |||
| Sebastian Zamorano | |||
| P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| Regulation of autophagy by the inositol trisphosphate receptor | Q24294716 | ||
| Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 | ||
| ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | Q24298956 | ||
| Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion | Q24299994 | ||
| Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53 | Q24300781 | ||
| Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1 | Q24302166 | ||
| Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1 | Q24303558 | ||
| A stapled BID BH3 helix directly binds and activates BAX | Q24307663 | ||
| BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha | Q24310536 | ||
| Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast | Q24314476 | ||
| AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response | Q24314664 | ||
| Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha | Q24322072 | ||
| PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum | Q24337674 | ||
| Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix | Q24537504 | ||
| Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor | Q24569647 | ||
| Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene | Q24617547 | ||
| Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway | Q24671908 | ||
| IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
| The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response | Q27933479 | ||
| A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response | Q27938493 | ||
| Induction of autophagy and inhibition of tumorigenesis by beclin 1 | Q28131718 | ||
| Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy | Q28131727 | ||
| Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21 | Q28138953 | ||
| BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria | Q28205892 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Cell death: critical control points | Q28240722 | ||
| BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. | Q40439042 | ||
| The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity. | Q40445820 | ||
| Dissection of Arabidopsis Bax inhibitor-1 suppressing Bax-, hydrogen peroxide-, and salicylic acid-induced cell death | Q40608225 | ||
| Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons | Q40669010 | ||
| Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum | Q41889229 | ||
| Pharmacological manipulation of Bcl-2 family members to control cell death | Q42115619 | ||
| Anti-apoptotic protein Bcl-2 interacts with and destabilizes the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA). | Q42808518 | ||
| BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum | Q43431138 | ||
| Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. | Q44251931 | ||
| BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis | Q44280749 | ||
| Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function. | Q46060884 | ||
| Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress. | Q46431069 | ||
| Proapoptotic BID is an ATM effector in the DNA-damage response | Q46669145 | ||
| Displacement of SERCA from SR lipid caveolae-related domains by Bcl-2: a possible mechanism for SERCA inactivation | Q46875789 | ||
| The inositol trisphosphate receptor in the control of autophagy | Q48406946 | ||
| ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. | Q53616050 | ||
| Conformational diseases and ER stress-mediated cell death: apoptotic cell death and autophagic cell death. | Q53637067 | ||
| Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies | Q79370601 | ||
| BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L) | Q80167533 | ||
| The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis | Q80352679 | ||
| Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis | Q80795514 | ||
| Emerging roles of the unfolded protein response signaling in physiology and disease | Q82528503 | ||
| ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells | Q28307506 | ||
| Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
| Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum | Q28506206 | ||
| Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress | Q28506667 | ||
| Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 | Q28507338 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| ER stress contributes to ischemia-induced cardiomyocyte apoptosis | Q28584083 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| Dual role of proapoptotic BAD in insulin secretion and beta cell survival | Q28586275 | ||
| Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis | Q28588618 | ||
| Role of Bax and Bak in mitochondrial morphogenesis | Q28591724 | ||
| BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress | Q28592598 | ||
| BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis | Q28594183 | ||
| The mammalian unfolded protein response | Q29547400 | ||
| An inhibitor of Bcl-2 family proteins induces regression of solid tumours | Q29547595 | ||
| JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy | Q29614479 | ||
| Autophagy is activated for cell survival after endoplasmic reticulum stress | Q29614485 | ||
| IRE1 signaling affects cell fate during the unfolded protein response | Q29615502 | ||
| BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly | Q29617135 | ||
| ER stress triggers apoptosis by activating BH3-only protein Bim | Q29617730 | ||
| Mitofusin 2 tethers endoplasmic reticulum to mitochondria | Q29619861 | ||
| Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus | Q29620179 | ||
| BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis | Q29620466 | ||
| Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics | Q29620467 | ||
| Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress | Q30164007 | ||
| Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis. | Q30554728 | ||
| Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast | Q31031519 | ||
| Identification of a network involved in thapsigargin-induced apoptosis using a library of small interfering RNA expression vectors | Q31120935 | ||
| Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response | Q33264844 | ||
| Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines | Q34014024 | ||
| Organelle-specific initiation of cell death pathways | Q34443559 | ||
| Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia. | Q34458933 | ||
| Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury | Q34479417 | ||
| Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression | Q34563098 | ||
| Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression | Q34631694 | ||
| BNips: a group of pro-apoptotic proteins in the Bcl-2 family | Q35135756 | ||
| Regulation of apoptosis by endoplasmic reticulum pathways. | Q35591699 | ||
| Endoplasmic reticulum stress triggers autophagy | Q35690087 | ||
| Autophagy: in sickness and in health | Q35753167 | ||
| BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives | Q35838773 | ||
| Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability | Q35916071 | ||
| Misfolded proteins, endoplasmic reticulum stress and neurodegeneration | Q35941821 | ||
| The role of BH3-only proteins in the immune system | Q36047162 | ||
| Transcription, apoptosis and p53: catch-22. | Q36056198 | ||
| The dynamic ER: experimental approaches and current questions | Q36173521 | ||
| Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis | Q36288687 | ||
| Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. | Q36322335 | ||
| Stressing out the ER: a role of the unfolded protein response in prion-related disorders | Q36393488 | ||
| ER stress, hypoxia tolerance and tumor progression. | Q36393499 | ||
| Endoplasmic reticulum stress-induced apoptosis and auto-immunity in diabetes | Q36393503 | ||
| ER stress and UPR in familial amyotrophic lateral sclerosis. | Q36393508 | ||
| The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases | Q36393512 | ||
| The control of endoplasmic reticulum-initiated apoptosis by the BCL-2 family of proteins | Q36393516 | ||
| The role of the endoplasmic reticulum in the accumulation of beta-amyloid peptide in Alzheimer's disease | Q36393522 | ||
| BH3-only proteins in cell death initiation, malignant disease and anticancer therapy. | Q36463059 | ||
| Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities | Q36490192 | ||
| Bcl-2 and Ca2+ homeostasis in the endoplasmic reticulum | Q36490197 | ||
| BCL2 family in DNA damage and cell cycle control | Q36501194 | ||
| Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. | Q36870862 | ||
| The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology | Q37031106 | ||
| Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress | Q39024302 | ||
| BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins | Q39261543 | ||
| Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak | Q39865156 | ||
| Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. | Q39962425 | ||
| Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. | Q40179972 | ||
| Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. | Q40202994 | ||
| The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R | Q40369800 | ||
| A role for proapoptotic BID in the DNA-damage response | Q40381562 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| P304 | page(s) | 33-47 | |
| P577 | publication date | 2010-01-01 | |
| P1433 | published in | Advances in Experimental Medicine and Biology | Q4686385 |
| P1476 | title | Alternative functions of the BCL-2 protein family at the endoplasmic reticulum | |
| Alternative Functions of the BCL-2 Protein Family at the Endoplasmic Reticulum | |||
| P478 | volume | 687 |
| Q35313600 | Apoptotic events induced by high glucose in human hepatoma HepG2 cells involve endoplasmic reticulum stress and MAPK's activation |
| Q53255347 | Appearance of nuclear-sorted caspase-12 fragments in cerebral cortical and hippocampal neurons in rats damaged by autologous blood clot embolic brain infarctions. |
| Q42452457 | Autophagy inhibition induces podocyte apoptosis by activating the pro-apoptotic pathway of endoplasmic reticulum stress |
| Q38699105 | Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death |
| Q39391422 | Heat-shock proteins attenuate SERCA inactivation by the anti-apoptotic protein Bcl-2: possible implications for the ER Ca2+-mediated apoptosis |
| Q98623164 | The critical role of PPARα in the binary switch between life and death induced by endoplasmic reticulum stress |
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