Initial combination therapy with metformin, pioglitazone and exenatide is more effective than sequential add-on therapy in subjects with new-onset diabetes. Results from the Efficacy and Durability of Initial Combination Therapy for Type 2 Diabetes

scientific article published on 07 January 2015

Initial combination therapy with metformin, pioglitazone and exenatide is more effective than sequential add-on therapy in subjects with new-onset diabetes. Results from the Efficacy and Durability of Initial Combination Therapy for Type 2 Diabetes is …
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scholarly articleQ13442814

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P356DOI10.1111/DOM.12417
P932PMC publication ID5577982
P698PubMed publication ID25425451

P50authorRalph A. DeFronzoQ58689309
P2093author name stringJ Adams
C Triplitt
E Cersosimo
M A Abdul-Ghani
C Puckett
D Maggs
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Safety and efficacy of once-weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes over 84 weeksQ41831179
Comparison of insulin degludec with insulin glargine in insulin-naive subjects with Type 2 diabetes: a 2-year randomized, treat-to-target trialQ41832904
Glycemic control and treatment failure with pioglitazone versus glibenclamide in type 2 diabetes mellitus: a 42-month, open-label, observational, primary care studyQ42691702
Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: results from the Veterans Administration Genetic Epidemiology StudyQ43959543
The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single doseQ44493423
Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men.Q44924385
P433issue3
P921main subjectmetforminQ19484
type 2 diabetesQ3025883
P304page(s)268-275
P577publication date2015-01-07
P1433published inDiabetes, Obesity and MetabolismQ5270109
P1476titleInitial combination therapy with metformin, pioglitazone and exenatide is more effective than sequential add-on therapy in subjects with new-onset diabetes. Results from the Efficacy and Durability of Initial Combination Therapy for Type 2 Diabetes (EDICT): a randomized trial
P478volume17

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