Drug-target networks for Tanshinone IIA identified by data mining

scientific article published on 01 October 2015

Drug-target networks for Tanshinone IIA identified by data mining is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S1875-5364(15)30075-3
P698PubMed publication ID26481375

P2093author name stringShao-Jun Chen
P2860cites workCytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationQ24616946
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewQ27008867
Network biology: understanding the cell's functional organizationQ27861027
Network pharmacology: the next paradigm in drug discoveryQ28297997
STITCH: interaction networks of chemicals and proteinsQ28465606
Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomesQ44803775
Inhibition of osteoclast differentiation and bone resorption by tanshinone IIA isolated from Salvia miltiorrhiza BungeQ44842680
Tanshinone II-A: new perspectives for old remediesQ45746307
Tanshinone IIA suppresses lung injury and apoptosis, and modulates protein kinase B and extracellular signal‐regulated protein kinase pathways in rats challenged with seawater exposureQ45841986
c-Src-dependent transactivation of PDGFR contributes to TNF-α-induced MMP-9 expression and functional impairment in osteoblastsQ46399877
An architecture for biological information extraction and representationQ48507596
Protein-protein interaction network analysis and gene set enrichment analysis in epilepsy patients with brain cancerQ48869986
Computing topological parameters of biological networksQ51900389
Network pharmacologyQ57932497
Target network analysis of adiponectin, a multifaceted adipokineQ85563401
Use of Natural Products as Chemical Library for Drug Discovery and Network PharmacologyQ28487019
Identifying chemicals with potential therapy of HIV based on protein-protein and protein-chemical interaction networkQ28533728
Novel factors in the pathogenesis of psoriasis and potential drug candidates are found with systems biology approachQ28535430
A travel guide to Cytoscape pluginsQ29788355
STITCH 3: zooming in on protein-chemical interactionsQ30002340
Systematic identification of proteins that elicit drug side effectsQ30002377
Topological analysis and interactive visualization of biological networks and protein structuresQ30414346
Drug discovery in the age of systems biology: the rise of computational approaches for data integration.Q30485238
Sodium tanshinone IIA sulfonate protects rat myocardium against ischemia-reperfusion injury via activation of PI3K/Akt/FOXO3A/Bim pathwayQ33551875
SRC: A Century of Science Brought to the ClinicQ34041298
Predicting new molecular targets for rhein using network pharmacologyQ34203691
Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA.Q34382511
Visual data mining of biological networks: one size does not fit all.Q34557957
Network pharmacology-based prediction of the multi-target capabilities of the compounds in Taohong Siwu decoction, and their application in osteoarthritisQ34917499
Tanshinone IIA exhibits anticonvulsant activity in zebrafish and mouse seizure models.Q34927731
Retracted: TNF-α Induces Cytosolic Phospholipase A2 Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 ActivationQ34998514
Detecting overlapping protein complexes in protein-protein interaction networksQ36528169
Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.Q36637897
Hubba: hub objects analyzer--a framework of interactome hubs identification for network biologyQ36749291
Network pharmacology: a new approach for chinese herbal medicine researchQ36900056
Cytochromes p450: roles in diseasesQ36928922
Neuroprotective effects of tanshinone I from Danshen extract in a mouse model of hypoxia-ischemiaQ37264903
AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?Q37671290
Targeting inflammation by modulating the Jun/AP-1 pathwayQ37845556
Cardiovascular actions and therapeutic potential of tanshinone IIAQ37903088
The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches.Q37996420
Network cluster analysis of protein-protein interaction network identified biomarker for early onset colorectal cancerQ38483765
Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo.Q39094910
Exploring and challenging the network of angiogenesis.Q39120436
Tanshinone IIA induces autophagic cell death via activation of AMPK and ERK and inhibition of mTOR and p70 S6K in KBM-5 leukemia cellsQ39132731
Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL‐6/STAT3/NF‐kB signaling pathwaysQ39171958
Tanshinone IIA protects PC12 cells from β-amyloid25–35-induced apoptosis via PI3K/Akt signaling pathwayQ39399964
Significant overlapping modules and biological processes between stroke and coronary heart diseaseQ42634622
Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitroQ42967378
Tanshinone IIA inhibits smooth muscle proliferation and intimal hyperplasia in the rat carotid balloon-injured model through inhibition of MAPK signaling pathwayQ43110452
Protective effect of Tanshinone IIA against infarct size and increased HMGB1, NFκB, GFAP and apoptosis consequent to transient middle cerebral artery occlusionQ44021066
P433issue10
P921main subjectdata miningQ172491
P304page(s)751-759
P577publication date2015-10-01
P1476titleDrug-target networks for Tanshinone IIA identified by data mining
P478volume13

Reverse relations

cites work (P2860)
Q91575139Tanshinone IIA combined with cisplatin synergistically inhibits non-small-cell lung cancer in vitro and in vivo via down-regulating the phosphatidylinositol 3-kinase/Akt signalling pathway
Q58101390The anticancer mechanism investigation of Tanshinone II by pharmacological clustering in protein network

Search more.