Nikhil V Munshi

researcher

Nikhil V Munshi is …
instance of (P31):
humanQ5

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P496ORCID iD0000-0002-8397-100X

P734family nameMunshiQ36986483
MunshiQ36986483
MunshiQ36986483
P735given nameNikhilQ1990189
NikhilQ1990189
P106occupationresearcherQ1650915

Reverse relations

author (P50)
Q441176502-Methoxyestradiol overcomes drug resistance in multiple myeloma cells
Q41009823A Genome-Wide Association Study Identifies a Novel Locus for Bortezomib-Induced Peripheral Neuropathy in European Patients with Multiple Myeloma.
Q61905635A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
Q37709866A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications
Q33944281A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma
Q88611111A phase 2 study of modified lenalidomide, bortezomib and dexamethasone in transplant-ineligible multiple myeloma
Q33412684A phase 2 trial of lenalidomide, bortezomib, and dexamethasone in patients with relapsed and relapsed/refractory myeloma
Q33395607A phase I safety study of enzastaurin plus bortezomib in the treatment of relapsed or refractory multiple myeloma
Q33834752A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in multiple myeloma cells
Q37035836APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment.
Q44098361Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications
Q64931827Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.
Q36835070Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu
Q40380103Antimyeloma activity of heat shock protein-90 inhibition.
Q39827794Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
Q40606773Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma
Q39966416Aplidin, a marine organism-derived compound with potent antimyeloma activity in vitro and in vivo
Q44010411Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications
Q24670297Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo
Q37201984Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: therapeutic implications
Q34523149Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications
Q88141406Biomarkers of bone remodeling in multiple myeloma patients to tailor bisphosphonate therapy
Q24598483Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma
Q37202761Bortezomib in the front-line treatment of multiple myeloma
Q34418462Bortezomib in the management of multiple myeloma.
Q37291635Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells
Q36206430Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma
Q30487339CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Q79323648Can thalidomide improve outcome in patients with multiple myeloma?
Q38805629Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model.
Q35125918Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients
Q34648345Classify hyperdiploidy status of multiple myeloma patients using gene expression profiles
Q44045389Clinical, radiographic, and biochemical characterization of multiple myeloma patients with osteonecrosis of the jaw.
Q35859205Combination of a Selective HSP90α/β Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells
Q36407209Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma
Q40524119Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma
Q28383385Compartment-Specific Bioluminescence Imaging platform for the high-throughput evaluation of antitumor immune function
Q33620440Conflicts of interest, authorship, and disclosures in industry-related scientific publications
Q37835572Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2.
Q37835574Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3.
Q37835571Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1.
Q40720850Cytokines modulate telomerase activity in a human multiple myeloma cell line.
Q64112513Deciphering the chronology of copy number alterations in Multiple Myeloma
Q41702673Development of extramedullary myeloma in the era of novel agents: no evidence of increased risk with lenalidomide-bortezomib combinations
Q34508343Differential and limited expression of mutant alleles in multiple myeloma
Q24673367Differential epitope mapping of antibodies to PDC-E2 in patients with hematologic malignancies after allogeneic hematopoietic stem cell transplantation and primary biliary cirrhosis
Q80395737Does maintenance therapy with thalidomide benefit patients with multiple myeloma?
Q38361677Early or delayed transplantation for multiple myeloma in the era of novel therapy: does one size fit all?
Q40626130Effects of oligonucleotide N3'-->P5' thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells
Q30431530Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma
Q37457302Emerging treatments for multiple myeloma: beyond immunomodulatory drugs and bortezomib
Q36289316Emerging trends in the clinical use of bortezomib in multiple myeloma
Q33967101Endothelial stress products and coagulation markers in patients with multiple myeloma treated with lenalidomide plus dexamethasone: an observational study
Q36651351Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells
Q40314855FQPD, a novel immunomodulatory drug, has significant in vitro activity in multiple myeloma
Q89228016Functional cargo delivery into mouse and human fibroblasts using a versatile microfluidic device
Q30490975Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target.
Q95648939Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression
Q88636696Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing
Q24670205Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor
Q37528285Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
Q50533942Histone deacetylase (HDAC) inhibitor ACY241 enhances anti-tumor activities of antigen-specific central memory cytotoxic T lymphocytes against multiple myeloma and solid tumors.
Q40402220Human anti-CD40 antagonist antibody triggers significant antitumor activity against human multiple myeloma
Q38359832Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays
Q40749337Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays
Q58792995Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Q44598249Immunomodulatory drug costimulates T cells via the B7-CD28 pathway
Q40339607Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: clinical implications
Q34369823Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma
Q33902726In vitro and in vivo antitumor activity of a novel alkylating agent, melphalan-flufenamide, against multiple myeloma cells
Q36902187In vitro anti-myeloma activity of the Aurora kinase inhibitor VE-465.
Q40087316Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells
Q58554182Insights into the genomic landscape of MYD88 wild-type Waldenström macroglobulinemia
Q40629582Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3'-kinase/AKT signaling.
Q36902184Interactions of the Hdm2/p53 and proteasome pathways may enhance the antitumor activity of bortezomib
Q38832525International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma
Q36929923International Myeloma Working Group recommendations for the treatment of multiple myeloma-related bone disease
Q37098847Intracellular NAD⁺ depletion enhances bortezomib-induced anti-myeloma activity
Q37986287Latest advances and current challenges in the treatment of multiple myeloma
Q38874291Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma
Q33973877Lenalidomide in multiple myeloma: an evidence-based review of its role in therapy
Q46549116Lenalidomide plus dexamethasone is efficacious in patients with relapsed or refractory multiple myeloma
Q38852886Lenalidomide, Bortezomib, and Dexamethasone with Transplantation for Myeloma.
Q33389111Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
Q38611142Logic programming reveals alteration of key transcription factors in multiple myeloma
Q88636701Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma
Q37925775MGUS and smoldering myeloma: the most prevalent of plasma cell dyscrasias.
Q79188378MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo
Q37978343Management of myeloma-associated renal dysfunction in the era of novel therapies
Q85048468Management of relapsed and relapsed/refractory multiple myeloma
Q37898151Managing multiple myeloma: the emerging role of novel therapies and adapting combination treatment for higher risk settings
Q40566183Mechanisms by which SGN-40, a humanized anti-CD40 antibody, induces cytotoxicity in human multiple myeloma cells: clinical implications
Q57151125Minimal residual disease negativity using deep sequencing is a major prognostic factor in multiple myeloma
Q37533983Mobilization in myeloma revisited: IMWG consensus perspectives on stem cell collection following initial therapy with thalidomide-, lenalidomide-, or bortezomib-containing regimens
Q33702365Molecular and cellular effects of multi-targeted cyclin-dependent kinase inhibition in myeloma: biological and clinical implications
Q40453614Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.
Q44189620Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.
Q44280918Molecular sequelae of histone deacetylase inhibition in human malignant B cells
Q34393832Molecular sequelae of proteasome inhibition in human multiple myeloma cells
Q33386405Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma
Q36839270Multiple myeloma: a prototypic disease model for the characterization and therapeutic targeting of interactions between tumor cells and their local microenvironment
Q34521393NF-kappa B as a therapeutic target in multiple myeloma
Q44484456NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma
Q36865500New drugs for myeloma
Q33621610Novel anti-B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma.
Q34996147Novel biologically based therapies for multiple myeloma
Q37624943Novel therapies in the treatment of multiple myeloma
Q78762135Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein
Q33414827Outcomes in patients with relapsed or refractory multiple myeloma in a phase I study of everolimus in combination with lenalidomide
Q64086734PAN-INTACT enables direct isolation of lineage-specific nuclei from fibrous tissues
Q34124937PI3K/p110{delta} is a novel therapeutic target in multiple myeloma
Q36170645Pathological crystallization of human immunoglobulins
Q92036531Pembrolizumab combined with lenalidomide and low-dose dexamethasone for relapsed or refractory multiple myeloma: phase I KEYNOTE-023 study
Q44442859Perifosine plus bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma previously treated with bortezomib: results of a multicenter phase I/II trial
Q40328451Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells
Q34008578Phase 1 study of pomalidomide MTD, safety, and efficacy in patients with refractory multiple myeloma who have received lenalidomide and bortezomib
Q33941043Phase transitions in human IgG solutions
Q36328301Phenotypically silent Cre recombination within the postnatal ventricular conduction system
Q24643402Prognostic significance of copy-number alterations in multiple myeloma
Q88470620Prospective Evaluation of Magnetic Resonance Imaging and [18F]Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography at Diagnosis and Before Maintenance Therapy in Symptomatic Patients With Multiple Myeloma Included in the IFM/DFCI 2009
Q40464000Proteasomal degradation of topoisomerase I is preceded by c-Jun NH2-terminal kinase activation, Fas up-regulation, and poly(ADP-ribose) polymerase cleavage in SN38-mediated cytotoxicity against multiple myeloma.
Q44662272Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma
Q34526773Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model
Q34398382Pyk2 promotes tumor progression in multiple myeloma
Q38059720Response assessment in Waldenström macroglobulinaemia: update from the VIth International Workshop
Q40259847Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment
Q35220653Role of additional chromosomal changes in the prognostic value of t(4;14) and del(17p) in multiple myeloma: the IFM experience
Q92372452Selective targeting of multiple myeloma by B cell maturation antigen (BCMA)-specific central memory CD8+ cytotoxic T lymphocytes: immunotherapeutic application in vaccination and adoptive immunotherapy
Q37280739Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy
Q43046672Tailoring treatment for multiple myeloma patients with relapsed and refractory disease
Q40017245Targeting Akt and heat shock protein 90 produces synergistic multiple myeloma cell cytotoxicity in the bone marrow microenvironment
Q35989478Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis
Q81248007Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma
Q36352540Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.
Q44951900Targeting mitochondria to overcome conventional and bortezomib/proteasome inhibitor PS-341 resistance in multiple myeloma (MM) cells
Q35616060Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM)
Q36506849The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival
Q35700723The Medical Research Council Myeloma IX trial: the impact on treatment paradigms
Q38852406The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.
Q53947641The biological sequelae of stromal cell-derived factor-1alpha in multiple myeloma.
Q40569001The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance
Q91157806The evolving role of transplantation in multiple myeloma: the need for a heterogeneous approach to a heterogeneous disease
Q39840677The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo
Q83387231The potential benefits of participating in early-phase clinical trials in multiple myeloma: long-term remission in a patient with relapsed multiple myeloma treated with 90 cycles of lenalidomide and bortezomib
Q44211035The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications
Q36998198The role of the bone marrow microenvironment in the pathophysiology of myeloma and its significance in the development of more effective therapies
Q36501937The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: interplay of growth factors, their receptors and stromal interactions
Q35006859The shaping and functional consequences of the dosage effect landscape in multiple myeloma
Q42044723The treatment of multiple myeloma patients not eligible for asct
Q37007400The treatment of relapsed and refractory multiple myeloma
Q44123720The vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584 inhibits growth and migration of multiple myeloma cells in the bone marrow microenvironment
Q34106817Treatment recommendations for patients with Waldenström macroglobulinemia (WM) and related disorders: IWWM-7 consensus
Q35116846Treatment recommendations in Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia.
Q37207049Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity.
Q36761567Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humans
Q33732491Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma
Q37128664Vaccination with dendritic cell/tumor fusions following autologous stem cell transplant induces immunologic and clinical responses in multiple myeloma patients
Q47861350Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma
Q33394281Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study
Q40504955p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells
Q40382947p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma
Q93170062pouC Regulates Expression of bmp4 During Atrioventricular Canal Formation in Zebrafish

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