review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Helena E Richardson | |
John E La Marca | |||
P2860 | cites work | Hallmarks of Cancer: The Next Generation | Q22252312 |
Regulation of cell adhesion and collective cell migration by hindsight and its human homolog RREB1 | Q24318130 | ||
Involvement of Lgl and Mahjong/VprBP in cell competition | Q24339418 | ||
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma | Q24607661 | ||
Advances in Engineering the Fly Genome with the CRISPR-Cas System. | Q47199964 | ||
JNK, p38, ERK, and SGK1 Inhibitors in Cancer. | Q47265464 | ||
Feedback amplification loop drives malignant growth in epithelial tissues | Q47741462 | ||
Signalling crosstalk during early tumorigenesis in the absence of Polycomb silencing | Q48193312 | ||
JNK signaling controls border cell cluster integrity and collective cell migration. | Q48759014 | ||
A whole-animal platform to advance a clinical kinase inhibitor into new disease space | Q49884409 | ||
Loss of Rab5 drives non-autonomous cell proliferation through TNF and Ras signaling in Drosophila | Q50449552 | ||
dUev1a modulates TNF-JNK mediated tumor progression and cell death in Drosophila. | Q50946112 | ||
Slit-Robo Repulsive Signaling Extrudes Tumorigenic Cells from Epithelia. | Q51247891 | ||
An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model. | Q51604185 | ||
Caspase inhibition during apoptosis causes abnormal signalling and developmental aberrations in Drosophila. | Q52086513 | ||
Modelling Cooperative Tumorigenesis in Drosophila. | Q52310247 | ||
Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways. | Q52652438 | ||
Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila. | Q52668701 | ||
Lgl, the SWH pathway and tumorigenesis: It's a matter of context & competition! | Q52708462 | ||
A drosophila model for EGFR-Ras and PI3K-dependent human glioma | Q27312887 | ||
A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila | Q28541015 | ||
JNK phosphorylates paxillin and regulates cell migration | Q28575982 | ||
Regulation of mixed-lineage kinase activation in JNK-dependent morphogenesis | Q30156053 | ||
The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy | Q30494710 | ||
Group choreography: mechanisms orchestrating the collective movement of border cells | Q30583756 | ||
Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs | Q33506529 | ||
A quantitative RNAi screen for JNK modifiers identifies Pvr as a novel regulator of Drosophila immune signaling | Q33515267 | ||
Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion | Q33715310 | ||
Rho1 regulates apoptosis via activation of the JNK signaling pathway at the plasma membrane. | Q33799194 | ||
GLYAT regulates JNK-mediated cell death in Drosophila | Q33899206 | ||
Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model | Q33947948 | ||
In vivo RNAi: today and tomorrow | Q34014698 | ||
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling | Q34034164 | ||
A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway | Q34093277 | ||
A Genetic Screen in Drosophila for Metastatic Behavior | Q34269141 | ||
A targeted UAS-RNAi screen in Drosophila larvae identifies wound closure genes regulating distinct cellular processes. | Q34285700 | ||
The Dpp/TGFβ-dependent corepressor Schnurri protects epithelial cells from JNK-induced apoptosis in drosophila embryos | Q34451563 | ||
Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors. | Q34570927 | ||
De-regulation of JNK and JAK/STAT signaling in ESCRT-II mutant tissues cooperatively contributes to neoplastic tumorigenesis | Q34589732 | ||
A Drosophila model of multiple endocrine neoplasia type 2. | Q34589821 | ||
Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila | Q34765996 | ||
Mixed-lineage kinase control of JNK and p38 MAPK pathways | Q34810173 | ||
Impaired Hippo signaling promotes Rho1-JNK-dependent growth. | Q35037903 | ||
Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis | Q35060075 | ||
The immune response of Drosophila | Q35577920 | ||
Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation. | Q35612440 | ||
Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion. | Q35669695 | ||
Tumor suppression by cell competition through regulation of the Hippo pathway | Q35673635 | ||
BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila. | Q35711047 | ||
Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors | Q35864565 | ||
A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila | Q35910934 | ||
Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium | Q40052869 | ||
Invasive cell behavior during Drosophila imaginal disc eversion is mediated by the JNK signaling cascade | Q40516370 | ||
Rho1-Wnd signaling regulates loss-of-cell polarity-induced cell invasion in Drosophila. | Q40952650 | ||
The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling | Q40995001 | ||
The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth. | Q41072283 | ||
A dp53/JNK-dependant feedback amplification loop is essential for the apoptotic response to stress in Drosophila | Q41087838 | ||
The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling. | Q41327267 | ||
Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila | Q42040197 | ||
The transcriptional response to tumorigenic polarity loss in Drosophila. | Q42118286 | ||
Hippo signaling promotes JNK-dependent cell migration | Q42318129 | ||
The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition | Q42504319 | ||
A non-cell-autonomous tumor suppressor role for Stat in eliminating oncogenic scribble cells. | Q42515031 | ||
An innate immune response of blood cells to tumors and tissue damage in Drosophila | Q42614126 | ||
Interplay among Drosophila transcription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy | Q43151067 | ||
A Jnk-Rho-Actin remodeling positive feedback network directs Src-driven invasion. | Q43551948 | ||
Mitochondrial defects trigger proliferation of neighbouring cells via a senescence-associated secretory phenotype in Drosophila | Q45034131 | ||
dPak is required for integrity of the leading edge cytoskeleton during Drosophila dorsal closure but does not signal through the JNK cascade | Q45175389 | ||
Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila. | Q46302676 | ||
Tumor-promoting function of apoptotic caspases by an amplification loop involving ROS, macrophages and JNK in Drosophila | Q46314637 | ||
Ras promotes cell survival in Drosophila by downregulating hid expression | Q47070193 | ||
Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling | Q47070215 | ||
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila | Q47070626 | ||
Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily | Q47070769 | ||
The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. | Q47071054 | ||
hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement. | Q47071857 | ||
Active JNK-dependent secretion of Drosophila Tyrosyl-tRNA synthetase by loser cells recruits haemocytes during cell competition | Q47072184 | ||
Yorkie regulates epidermal wound healing in Drosophila larvae independently of cell proliferation and apoptosis. | Q47149836 | ||
Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure. | Q52714687 | ||
Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila. | Q52744366 | ||
JNK signaling is converted from anti- to pro-tumor pathway by Ras-mediated switch of Warts activity. | Q52803010 | ||
JNK and Yorkie drive tumor progression by generating polyploid giant cells in Drosophila. | Q53435093 | ||
Short-term activation of the Jun N-terminal kinase pathway in apoptosis-deficient cells of Drosophila induces tumorigenesis. | Q53829229 | ||
A Drosophila Tumor Suppressor Gene Prevents Tonic TNF Signaling through Receptor N-Glycosylation. | Q54976988 | ||
Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in Drosophila. | Q54978060 | ||
Notch signals modulate lgl mediated tumorigenesis by the activation of JNK signaling. | Q55262678 | ||
Polarity protein Canoe mediates overproliferation via modulation of JNK, Ras-MAPK and Hippo signalling | Q57452875 | ||
Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues | Q57802347 | ||
Epithelial cells release adenosine to promote local TNF production in response to polarity disruption | Q58599758 | ||
Cooperates with Oncogenic in Tumourigenesis via the JNK and PI3K Pathways in epithelial Tissue | Q59359925 | ||
Ask1 and Akt act synergistically to promote ROS-dependent regeneration in Drosophila | Q61810626 | ||
Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network | Q64086483 | ||
JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress | Q64228217 | ||
A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer | Q64277436 | ||
The Hippo Signaling Network and Its Biological Functions. | Q64980155 | ||
The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in | Q83230727 | ||
Drosophila bendless catalyzes K63-linked polyubiquitination and is involved in the response to DNA damage | Q88004120 | ||
Deltex interacts with Eiger and consequently influences the cell death in Drosophila melanogaster | Q88727752 | ||
Tankyrase regulates apoptosis by activating JNK signaling in Drosophila | Q89313767 | ||
Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster : I. Zygotic loci on the second chromosome | Q89559821 | ||
Drosophila Models of Cell Polarity and Cell Competition in Tumourigenesis | Q90103107 | ||
Pontin/Tip49 negatively regulates JNK-mediated cell death in Drosophila | Q90651764 | ||
Wingless modulates activator protein-1-mediated tumor invasion | Q91229306 | ||
Modeling Cancer with Flies and Fish | Q91823874 | ||
Drosophila jumu modulates apoptosis via a JNK-dependent pathway and is required for other processes in wing development | Q91846766 | ||
Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration | Q92043370 | ||
Role of D-GADD45 in JNK-Dependent Apoptosis and Regeneration in Drosophila | Q92164612 | ||
Lic regulates JNK-mediated cell death in Drosophila | Q92216284 | ||
Dynamic MAPK signaling activity underlies a transition from growth arrest to proliferation in Drosophila scribble mutant tumors | Q92351034 | ||
Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression | Q92602547 | ||
JNK signaling in cancer cell survival | Q92621149 | ||
Elimination of oncogenic cells that regulate epithelial homeostasis in Drosophila | Q92916660 | ||
Oncogenic Notch Triggers Neoplastic Tumorigenesis in a Transition-Zone-like Tissue Microenvironment | Q93080568 | ||
Strip and Cka negatively regulate JNK signalling during Drosophila spermatogenesis | Q95499517 | ||
Bacterial recognition and signalling by the Drosophila IMD pathway | Q36067616 | ||
Using Drosophila melanogaster to map human cancer pathways | Q36202195 | ||
Toll pathway modulates TNF-induced JNK-dependent cell death in Drosophila | Q36246981 | ||
Wallenda regulates JNK-mediated cell death in Drosophila | Q36346887 | ||
Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila | Q36509073 | ||
Caspase signalling in the absence of apoptosis drives Jnk-dependent invasion. | Q36680272 | ||
In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling | Q36790940 | ||
Localized JNK signaling regulates organ size during development | Q36844608 | ||
Chemical genetic discovery of targets and anti-targets for cancer polypharmacology | Q36988960 | ||
Apoptotic cells can induce non-autonomous apoptosis through the TNF pathway | Q37188252 | ||
In vivo genetic dissection of tumor growth and the Warburg effect | Q37270331 | ||
Ajuba family proteins link JNK to Hippo signaling. | Q37315284 | ||
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila | Q37367551 | ||
Apoptosis in Drosophila: compensatory proliferation and undead cells. | Q37402591 | ||
Signal integration by JNK and p38 MAPK pathways in cancer development | Q37560607 | ||
Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila. | Q37577436 | ||
PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis | Q37592539 | ||
The dark side of fly TNF: an ancient developmental proof reading mechanism turned into tumor promoter | Q37799217 | ||
The apical polarity protein network in Drosophila epithelial cells: regulation of polarity, junctions, morphogenesis, cell growth, and survival | Q38033612 | ||
Regulating cell morphogenesis: the Drosophila Jun N-terminal kinase pathway | Q38056459 | ||
The Drosophila TNF ortholog Eiger: emerging physiological roles and evolution of the TNF system | Q38224971 | ||
Recent progress in the design, study, and development of c-Jun N-terminal kinase inhibitors as anticancer agents. | Q38274267 | ||
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter | Q38497018 | ||
The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma | Q38842819 | ||
Cas9-Mediated Genome Engineering in Drosophila melanogaster | Q38944624 | ||
Modeling Human Cancers in Drosophila | Q39068929 | ||
JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila | Q39121816 | ||
Functional exploration of colorectal cancer genomes using Drosophila | Q39145987 | ||
The actin cross-linker Filamin/Cheerio mediates tumor malignancy downstream of JNK signaling. | Q39226343 | ||
The Kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP5. | Q39252840 | ||
PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation | Q39410909 | ||
Tissue-Intrinsic Tumor Hotspots: Terroir for Tumorigenesis. | Q39441362 | ||
Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway | Q39647447 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P304 | page(s) | 42 | |
P577 | publication date | 2020-02-05 | |
P1433 | published in | Frontiers in Cell and Developmental Biology | Q27725488 |
P1476 | title | Two-Faced: Roles of JNK Signalling During Tumourigenesis in the Drosophila Model | |
P478 | volume | 8 |
Q99365542 | Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells |
Q102210936 | Loss of the spectraplakin gene Short stop induces a DNA damage response in Drosophila epithelia |
Search more.