GM-CSF-Dependent Inflammatory Pathways

scientific article published on 04 September 2019

GM-CSF-Dependent Inflammatory Pathways is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2019.02055
P932PMC publication ID6737278
P698PubMed publication ID31552022

P2093author name stringJohn A Hamilton
P2860cites workGranulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammationQ80088055
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Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor SignalingQ27718099
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GM-CSF and IL-3 Modulate Human Monocyte TNF-α Production and Renewal in In Vitro Models of Trained Immunity.Q30835058
Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunizationQ31040402
GM-CSF produced by the airway epithelium is required for sensitization to cockroach allergenQ33559067
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axisQ33703008
Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.Q33826888
GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.Q33839932
Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiencyQ33881232
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Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell developmentQ34049333
Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPSQ34115841
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survivalQ34633876
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.Q34659689
RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.Q34660473
GM-CSF in inflammation and autoimmunity.Q34754737
The closely related CD103+ dendritic cells (DCs) and lymphoid-resident CD8+ DCs differ in their inflammatory functionsQ35122681
Innate response activator B cells protect against microbial sepsis.Q35757819
Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.Q36131723
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GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cellsQ36398839
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammationQ36520874
GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survivalQ36916371
Distinct Transcriptional Programs Control Cross-Priming in Classical and Monocyte-Derived Dendritic CellsQ37086985
Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.Q37151168
Colony-stimulating factors in inflammation and autoimmunity.Q37190439
Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarizationQ37193358
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF.Q37194936
Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammationQ37217530
The inflammatory cytokine, GM-CSF, alters the developmental outcome of murine dendritic cells.Q50795170
Reprogramming of monocytes by GM-CSF contributes to regulatory immune functions during intestinal inflammation.Q51661405
CCL17 blockade as a therapy for osteoarthritis pain and disease.Q52604134
TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17.Q52644010
GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis.Q53068398
The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.Q53820832
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.Q55431503
Defining GM-CSF- and macrophage-CSF-dependent macrophage responses by in vitro modelsQ57149911
Pharmacodynamic biomarkers and differential effects of TNF- and GM-CSF-targeting biologics in rheumatoid arthritisQ57791844
The Transcription Factors PU.1 and IRF4 Determine Dendritic Cell-Specific Expression of RALDH2Q58566120
GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and FunctionQ58698466
Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colony-stimulating factor in experimental inflammatory arthritisQ61955107
Rheumatoid arthritis: opposing actions of haemopoietic growth factors and slow-acting anti-rheumatic drugsQ61955184
Can DCs be distinguished from macrophages by molecular signatures?Q64447023
Synergistic activation of human monocytes by granulocyte-macrophage colony-stimulating factor and IFN-gamma. Increased TNF-alpha but not IL-1 activityQ70400790
Stimulation of macrophage plasminogen activator activity by colony-stimulating factorsQ72078052
Coordinate and noncoordinate colony stimulating factor formation by human monocytesQ72273937
Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiationQ77698627
GM-CSF primes cardiac inflammation in a mouse model of Kawasaki diseaseQ37272083
GM-CSF in the generation of dendritic cells from human blood monocyte precursors: recent advances.Q37300266
GM-CSF Grown Bone Marrow Derived Cells Are Composed of Phenotypically Different Dendritic Cells and Macrophages.Q37408243
Granulocyte macrophage colony-stimulating factor receptor α expression and its targeting in antigen-induced arthritis and inflammationQ37466119
Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation.Q37730878
Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.Q37734578
Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapyQ37983043
Colony stimulating factors and myeloid cell biology in health and disease.Q38045643
The transcriptional regulator network of human inflammatory macrophages is defined by open chromatin.Q38299850
Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophagesQ38319108
GM-CSF as a target in inflammatory/autoimmune disease: current evidence and future therapeutic potential.Q38369816
GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage.Q38598045
Targeting GM-CSF in inflammatory diseasesQ38657999
GM-CSF: From Growth Factor to Central Mediator of Tissue InflammationQ39010211
Anti-colony-stimulating factor therapies for inflammatory and autoimmune diseasesQ39056339
Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markersQ39578612
The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic CellsQ40172102
The nature and action of granulocyte-macrophage colony stimulating factorsQ40294239
Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways.Q40697788
GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells.Q40826938
Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis.Q40891825
Dysregulated hematopoietic stem and progenitor cell activity promotes interleukin-23-driven chronic intestinal inflammationQ41079801
Analysis of the developmental stages, kinetics, and phenotypes exhibited by myeloid cells driven by GM-CSF in vitro.Q41153792
Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System.Q41198470
CD1 molecule expression on human monocytes induced by granulocyte-macrophage colony-stimulating factorQ41578750
Targeting cholesterol homeostasis in lung diseasesQ41581562
Th1 is the predominant helper T cell subset that produces GM-CSF in the joint of rheumatoid arthritisQ41687192
Idiopathic pulmonary alveolar proteinosis as an autoimmune disease with neutralizing antibody against granulocyte/macrophage colony-stimulating factor.Q41921955
Breaking the vicious cycle between breast cancer cells and tumor-associated macrophages.Q43103557
GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.Q43774205
Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells.Q45296517
Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous SystemQ46413912
The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar MacrophagesQ47415620
Regulation of the class II MHC pathway in primary human monocytes by granulocyte-macrophage colony-stimulating factorQ47677644
The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytesQ47696973
Activities of granulocyte-macrophage colony-stimulating factor and interleukin-3 on monocytesQ47848263
Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages.Q48509512
IL-17 and GM-CSF expression are antagonistically regulated by human T helper cells.Q48708663
Investigational therapies targeting the granulocyte macrophage colony-stimulating factor receptor-α in rheumatoid arthritis: focus on mavrilimumabQ49393096
The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages.Q49779441
Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity.Q49958889
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)2055
P577publication date2019-09-04
P1433published inFrontiers in ImmunologyQ27723748
P1476titleGM-CSF-Dependent Inflammatory Pathways
P478volume10

Reverse relations

cites work (P2860)
Q93229804A strategy targeting monocyte-macrophage differentiation to avoid pulmonary complications in SARS-Cov2 infection
Q98177702Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition
Q98657521GM-CSF blockade with mavrilimumab in severe COVID-19 pneumonia and systemic hyperinflammation: a single-centre, prospective cohort study
Q99590940Host Immune Defense upon Fungal Infections with Mucorales: Pathogen-Immune Cell Interactions as Drivers of Inflammatory Responses
Q89621250Immunobiology of Cervix Ripening
Q90364705Lipoprotein profiling in early multiple sclerosis patients: effect of chronic inflammation?
Q100526688The efficacy and safety of targeting GM-CSF in arthritis
Q99400656The role of Interleukin 6 inhibitors in therapy of severe COVID-19
Q96591069Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities

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