review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Jianjun Chen | |
Huilin Huang | |||
Hengyou Weng | |||
P2860 | cites work | N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO | Q24293481 |
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites | Q24300072 | ||
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility | Q24304362 | ||
N6-methyladenosine-dependent regulation of messenger RNA stability | Q24310545 | ||
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO | Q24310886 | ||
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation | Q24311871 | ||
Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase | Q24315962 | ||
Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase | Q24318728 | ||
N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions | Q24320088 | ||
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq | Q24320240 | ||
N6-methyladenosine marks primary microRNAs for processing | Q24323516 | ||
N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency | Q24337939 | ||
Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene | Q24537653 | ||
VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. | Q52366303 | ||
The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency. | Q52371608 | ||
Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells | Q24563918 | ||
Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons | Q24598126 | ||
Methylation of nuclear simian virus 40 RNAs | Q24634149 | ||
Structural basis of N(6)-adenosine methylation by the METTL3-METTL14 complex | Q27709350 | ||
5' UTR m(6)A Promotes Cap-Independent Translation | Q28114851 | ||
Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing | Q28114974 | ||
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases | Q28117995 | ||
Dynamic m(6)A mRNA methylation directs translational control of heat shock response | Q28118495 | ||
HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events | Q28118781 | ||
The methylated constituents of L cell messenger RNA: evidence for an unusual cluster at the 5' terminus | Q28202411 | ||
Modified nucleosides and bizarre 5'-termini in mouse myeloma mRNA | Q28210505 | ||
5′-Terminal structures of poly(A)+ cytoplasmic messenger RNA and of poly(A)+ and poly(A)− heterogeneous nuclear RNA of cells of the dipteran Drosophila melanogaster | Q28237586 | ||
Localization of N6-methyladenosine in the Rous sarcoma virus genome | Q28252257 | ||
Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation | Q28511267 | ||
Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge | Q28552551 | ||
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells | Q28585513 | ||
Cytoplasmic m6A reader YTHDF3 promotes mRNA translation | Q29465772 | ||
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA. | Q29465801 | ||
Methyltransferase-like protein 16 binds the 3'-terminal triple helix of MALAT1 long noncoding RNA. | Q32884496 | ||
The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention | Q32884542 | ||
N6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein | Q33741052 | ||
Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA | Q34378909 | ||
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis | Q34448805 | ||
N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics | Q34508439 | ||
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA. | Q34519307 | ||
The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells | Q34523745 | ||
Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5 | Q34883200 | ||
WTAP is a novel oncogenic protein in acute myeloid leukemia | Q35206435 | ||
Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome | Q35804751 | ||
Nature and nurture - lessons from chemical carcinogenesis | Q36014330 | ||
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression? | Q37002361 | ||
YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex | Q37222906 | ||
IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer | Q37507920 | ||
Post-transcriptional gene regulation by mRNA modifications. | Q37515917 | ||
m6ASNP: a tool for annotating genetic variants by m6A function. | Q52607196 | ||
N6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential. | Q52660655 | ||
N6-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells. | Q53175872 | ||
Deregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression. | Q55089347 | ||
N-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression | Q56396035 | ||
A dynamic N-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors | Q57293800 | ||
Cross-talk among writers, readers, and erasers of mA regulates cancer growth and progression | Q57298223 | ||
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner | Q58106106 | ||
Methylation of Structured RNA by the mA Writer METTL16 Is Essential for Mouse Embryonic Development | Q58709961 | ||
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis | Q59082106 | ||
RNA mA modification enzymes shape innate responses to DNA by regulating interferon β | Q59350385 | ||
The role of the fat mass and obesity-associated protein in the proliferation of pancreatic cancer cells | Q61812189 | ||
Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer | Q64053337 | ||
KIAA1429 regulates the migration and invasion of hepatocellular carcinoma by altering m6A modification of ID2 mRNA | Q64064227 | ||
RNA mA methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail | Q64065752 | ||
Changes of N6-methyladenosine modulators promote breast cancer progression | Q64070357 | ||
METTL3 Promotes the Proliferation and Mobility of Gastric Cancer Cells | Q64072434 | ||
Excessive miR-25-3p maturation via N-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression | Q64097541 | ||
Mettl3-mediated mRNA mA methylation promotes dendritic cell activation | Q64097754 | ||
RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3 | Q64108135 | ||
ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2 | Q64113805 | ||
YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma | Q64245310 | ||
Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates | Q64272565 | ||
Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia | Q64460020 | ||
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. | Q64893136 | ||
EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis. | Q64971530 | ||
m6A modification controls the innate immune response to infection by targeting type I interferons | Q67200928 | ||
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally | Q68692501 | ||
Single-base mapping of m6A by an antibody-independent method | Q68693705 | ||
Characterization and partial purification of mRNA N6-adenosine methyltransferase from HeLa cell nuclei. Internal mRNA methylation requires a multisubunit complex | Q72037221 | ||
Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells | Q75719938 | ||
m6A demethylase FTO facilitates tumor progression in lung squamous cell carcinoma by regulating MZF1 expression | Q88905968 | ||
YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation | Q90025594 | ||
N6-Methyladenosine Modulates Nonsense-Mediated mRNA Decay in Human Glioblastoma | Q90147906 | ||
DART-seq: an antibody-free method for global m6A detection | Q90243294 | ||
N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation | Q90371346 | ||
ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation | Q90386634 | ||
METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance | Q90465747 | ||
The RNA m6A methyltransferase METTL3 promotes pancreatic cancer cell proliferation and invasion | Q90670508 | ||
METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer | Q90676584 | ||
An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells | Q90714266 | ||
Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m6A reader YTHDF3 | Q90751756 | ||
Critical Enzymatic Functions of FTO in Obesity and Cancer | Q90930461 | ||
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression | Q90950201 | ||
ALKBH5-m6A-FOXM1 signaling axis promotes proliferation and invasion of lung adenocarcinoma cells under intermittent hypoxia | Q91068102 | ||
The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network | Q91117885 | ||
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer | Q91185402 | ||
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma | Q91310549 | ||
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm | Q91346488 | ||
Mettl14 inhibits bladder TIC self-renewal and bladder tumorigenesis through N6-methyladenosine of Notch1 | Q91419120 | ||
RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrix metallopeptidase 2 | Q91574116 | ||
METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition | Q91698979 | ||
IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader | Q91718565 | ||
RNA m6A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway | Q91737536 | ||
ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1 | Q91759465 | ||
The Biogenesis and Precise Control of RNA m6A Methylation | Q91763924 | ||
m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis | Q91819611 | ||
RNA modifications modulate gene expression during development | Q91823437 | ||
Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis | Q91844964 | ||
The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells | Q91893522 | ||
METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing | Q91991150 | ||
The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112 | Q92061186 | ||
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3 | Q92128551 | ||
Roles and Regulation of Long Noncoding RNAs in Hepatocellular Carcinoma | Q92133179 | ||
RNA N 6-Methyladenosine Modification in Normal and Malignant Hematopoiesis | Q92140582 | ||
m6A mRNA methylation regulates CTNNB1 to promote the proliferation of hepatoblastoma | Q92212631 | ||
m6A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling | Q92450835 | ||
The m6A-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca2+ influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway | Q92497567 | ||
M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma | Q92501485 | ||
MiR-4429 prevented gastric cancer progression through targeting METTL3 to inhibit m6A-caused stabilization of SEC62 | Q92505912 | ||
The m6A demethylase FTO promotes the growth of lung cancer cells by regulating the m6A level of USP7 mRNA | Q92578561 | ||
N6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer | Q92600798 | ||
Oncogenic Role of an Epigenetic Reader of m6A RNA Modification: YTHDF1 in Merkel Cell Carcinoma | Q92702124 | ||
N 6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription | Q92711302 | ||
WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1 | Q92787270 | ||
Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG | Q92844891 | ||
DDX3 modulates cisplatin resistance in OSCC through ALKBH5-mediated m6A-demethylation of FOXM1 and NANOG | Q92892994 | ||
N6-methyladenosine METTL3 promotes the breast cancer progression via targeting Bcl-2 | Q92902790 | ||
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner | Q92956393 | ||
METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma | Q92966476 | ||
Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer | Q92977417 | ||
N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance | Q92985610 | ||
YTHDF2 suppresses cell proliferation and growth via destabilizing the EGFR mRNA in hepatocellular carcinoma | Q93037855 | ||
N6-Methyladenosine Modification Controls Circular RNA Immunity | Q93045003 | ||
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer | Q93056827 | ||
The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating the m6A level of LEF1 | Q93113487 | ||
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia | Q93129281 | ||
Deciphering the "m6A Code" via Antibody-Independent Quantitative Profiling | Q93137733 | ||
Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway | Q93157333 | ||
Long noncoding RNA GAS5-AS1 suppresses growth and metastasis of cervical cancer by increasing GAS5 stability | Q93187503 | ||
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells | Q37662078 | ||
The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer | Q38234648 | ||
m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways | Q38632272 | ||
m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program | Q38710467 | ||
RNA m6A methylation regulates the ultraviolet-induced DNA damage response. | Q38712170 | ||
m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency | Q39038754 | ||
Dynamic RNA Modifications in Gene Expression Regulation | Q39378718 | ||
RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated. | Q39508782 | ||
‘Cap’ structures in maize poly(A)-containing RNA | Q40243572 | ||
METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N6 -methyladenosine-dependent primary MicroRNA processing | Q40520642 | ||
Extensive translation of circular RNAs driven by N6-methyladenosine | Q41083717 | ||
Structural insights into the molecular mechanism of the m(6)A writer complex | Q41093229 | ||
Partial purification of a 6-methyladenine mRNA methyltransferase which modifies internal adenine residues | Q41784805 | ||
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis | Q41791644 | ||
Synthesis of a FTO inhibitor with anticonvulsant activity. | Q42040042 | ||
m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition | Q42130806 | ||
Coordination of m(6)A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming | Q42134417 | ||
YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. | Q42380468 | ||
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. | Q45067620 | ||
Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs. | Q46834664 | ||
m6A modulates haematopoietic stem and progenitor cell specification | Q47073270 | ||
N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3'-end processing | Q47128487 | ||
m6AVar: a database of functional variants involved in m6A modification | Q47159279 | ||
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification | Q47207720 | ||
FTO regulates the chemo-radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β-catenin through mRNA demethylation | Q47217954 | ||
R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. | Q47284426 | ||
The M6A methyltransferase METTL3: acting as a tumor suppressor in renal cell carcinoma | Q47314607 | ||
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control. | Q47352505 | ||
HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g. | Q47365935 | ||
RNA N6-methyladenosine methyltransferase METTL3 promotes liver cancer progression through YTHDF2 dependent post-transcriptional silencing of SOCS2. | Q47368330 | ||
YTH domain family 2 orchestrates epithelial-mesenchymal transition/proliferation dichotomy in pancreatic cancer cells | Q47405466 | ||
Role of N6-methyladenosine modification in cancer | Q47567064 | ||
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. | Q47583443 | ||
Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance | Q47602761 | ||
Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs. | Q47626728 | ||
Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations. | Q47816766 | ||
Knockdown of YTH N6-methyladenosine RNA binding protein 2 (YTHDF2) inhibits proliferation and promotes apoptosis in MGC-803 gastric cancer cells | Q49573889 | ||
The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells | Q49974458 | ||
Overexpression of YTHDF1 is associated with poor prognosis in patients with hepatocellular carcinoma | Q50034633 | ||
Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels | Q50105616 | ||
Smoke-Induced Changes to the Epigenome Provide Fertile Ground for Oncogenic Mutation | Q50131602 | ||
Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer | Q50322294 | ||
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. | Q50422081 | ||
MicroRNA-145 Modulates N6-Methyladenosine Levels by Targeting the 3'-Untranslated mRNA Region of the N6-Methyladenosine Binding YTH Domain Family 2 Protein. | Q51180526 | ||
FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. | Q51236778 | ||
RNA N6-methyladenosine modification in cancers: current status and perspectives. | Q52311777 | ||
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. | Q52352943 | ||
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d. | Q52357020 | ||
P433 | issue | 3 | |
P304 | page(s) | 270-288 | |
P577 | publication date | 2020-03-01 | |
P1433 | published in | Cancer Cell | Q280018 |
P1476 | title | m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer | |
P478 | volume | 37 |