Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites

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Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites is …
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scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2014.05.048
P3181OpenCitations bibliographic resource ID1786659
P932PMC publication ID4142486
P698PubMed publication ID24981863
P5875ResearchGate publication ID263550523

P50authorEric LanderQ970550
Aviv RegevQ4829027
Schraga SchwartzQ42317798
Rahul SatijaQ42799623
Nir HacohenQ42799920
Maxwell R MumbachQ56358258
Neville E SanjanaQ56380653
Steven A CarrQ59672393
Philipp MertinsQ90591285
Tarjei S MikkelsenQ90777086
Naomi HabibQ93270839
Elizaveta FreinkmanQ106388413
P2093author name stringFeng Zhang
Davide Cacchiarelli
Marko Jovanovic
Tim Wang
Dmitry Ter-Ovanesyan
G Guy Bushkin
Michael E Pacold
Karolina Maciag
P2860cites workAn integrated encyclopedia of DNA elements in the human genomeQ22122150
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertilityQ24304362
N6-methyladenosine-dependent regulation of messenger RNA stabilityQ24310545
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylationQ24311871
Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferaseQ24315962
Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferaseQ24318728
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seqQ24320240
Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycleQ24337790
Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 geneQ24537653
Current status and new features of the Consensus Coding Sequence databaseQ24567717
Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codonsQ24598126
High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosisQ27930684
The Saccharomyces cerevisiae MUM2 gene interacts with the DNA replication machinery and is required for meiotic levels of double strand breaksQ27934100
RNA methylation by the MIS complex regulates a cell fate decision in yeastQ27936524
Identification of WTAP, a novel Wilms' tumour 1-associating proteinQ28139416
Global quantification of mammalian gene expression controlQ28238103
HeLa cell RNA (2'-O-methyladenosine-N6-)-methyltransferase specific for the capped 5'-end of messenger RNAQ28272299
MODOMICS: a database of RNA modification pathways--2013 updateQ28278502
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cellsQ28585513
RNA-methylation-dependent RNA processing controls the speed of the circadian clockQ28591141
Genome-wide analysis of mammalian promoter architecture and evolutionQ29616717
Towards a knowledge-based Human Protein AtlasQ29617987
A paired-end sequencing strategy to map the complex landscape of transcription initiationQ30430247
The CRAPome: a contaminant repository for affinity purification-mass spectrometry dataQ30660043
The Drosophila melanogaster fl(2)d gene is needed for the female-specific splicing of Sex-lethal RNA.Q33924207
Linking promoters to functional transcripts in small samples with nanoCAGE and CAGEscanQ34003605
Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferaseQ34152368
Biochemical function of female-lethal (2)D/Wilms' tumor suppressor-1-associated proteins in alternative pre-mRNA splicing.Q34160093
Human housekeeping genes are compactQ34212688
Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNAQ34378909
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster.Q34498007
Methylated, blocked 5 termini in HeLa cell mRNAQ35079459
Drosophila Inducer of MEiosis 4 (IME4) is required for Notch signaling during oogenesisQ35202750
iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomicsQ36209046
Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell linesQ36622908
Methylated nucleotides block 5' terminus of HeLa cell messenger RNA.Q39923664
Characterization and partial purification of mRNA N6-adenosine methyltransferase from HeLa cell nuclei. Internal mRNA methylation requires a multisubunit complexQ72037221
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectMethyltransferase like 14Q21120849
Methyltransferase like 3Q21124024
WT1 associated proteinQ21132235
Vir like m6A methyltransferase associatedQ21135908
P304page(s)284-96
P577publication date2014-07-10
P1433published inCell ReportsQ5058165
P1476titlePerturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites
P478volume8

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Q89126899m6A RNA Methylation Controls Neural Development and Is Involved in Human Diseases
Q92617558m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment
Q47583443m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.
Q99346315m6A RNA Methylation in Cardiovascular Diseases
Q91749641m6A RNA methylation regulators can contribute to malignant progression and impact the prognosis of bladder cancer
Q98771745m6A Reader: Epitranscriptome Target Prediction and Functional Characterization of N 6-Methyladenosine (m6A) Readers
Q91451497m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2
Q91185402m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer
Q33865334m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.
Q64910335m6A methyltransferase METTL3 suppresses colorectal cancer proliferation and migration through p38/ERK pathways.
Q67200928m6A modification controls the innate immune response to infection by targeting type I interferons
Q99563534m6A modification in RNA: biogenesis, functions and roles in gliomas
Q92296071m6A modification of a 3' UTR site reduces RME1 mRNA levels to promote meiosis
Q47071868m6A modulates neuronal functions and sex determination in Drosophila
Q47159279m6AVar: a database of functional variants involved in m6A modification
Q64069753m6Acomet: large-scale functional prediction of individual mA RNA methylation sites from an RNA co-methylation network
Q38671556m6aViewer: software for the detection, analysis and visualization of N6-methyl-adenosine peaks from m6A-seq/ME-RIP sequencing data
Q58604866mA: Widespread regulatory control in virus replication
Q50073616mRNA Traffic Control Reviewed: N6-Methyladenosine (m6 A) Takes the Driver's Seat
Q89891127mRNA modification orchestrates cancer stem cell fate decisions
Q64976676trumpet: transcriptome-guided quality assessment of m6A-seq data.

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