Cooperative PSGL-1 and CXCR2 signaling in neutrophils promotes deep vein thrombosis in mice

scientific article published on 01 August 2018

Cooperative PSGL-1 and CXCR2 signaling in neutrophils promotes deep vein thrombosis in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2018-05-850859
P932PMC publication ID6161769
P698PubMed publication ID30068506

P50authorRodger P McEverQ88088306
P2093author name stringJasimuddin Ahamed
Zhenghui Liu
Tadayuki Yago
P2860cites workNeutrophil extracellular traps promote deep vein thrombosis in miceQ24604984
Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesionQ28508195
Elevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in miceQ28593286
Getting to the site of inflammation: the leukocyte adhesion cascade updatedQ29547271
Monocyte recruitment during infection and inflammationQ29620067
Mice lacking two or all three selectins demonstrate overlapping and distinct functions for each selectin.Q30304034
P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venulesQ30310860
The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flowQ30413749
Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rollingQ30426195
Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophilsQ30427418
CXCR2- and E-selectin-induced neutrophil arrest during inflammation in vivoQ30434720
PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rollingQ30439982
Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.Q30440643
P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flowQ30453100
The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cellsQ30490766
Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathwaysQ30494206
Signal-dependent slow leukocyte rolling does not require cytoskeletal anchorage of P-selectin glycoprotein ligand-1 (PSGL-1) or integrin αLβ2.Q30514480
Deep vein thrombosis resolution is modulated by monocyte CXCR2-mediated activity in a mouse modelQ47710811
Red blood cells in thrombosis.Q48003288
Circulating soluble P-selectin must dimerize to promote inflammation and coagulation in mice.Q48130520
Neutrophil extracellular traps in immunity and diseaseQ49485640
Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality.Q51903642
Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing.Q52577800
Selectins and chemokines use shared and distinct signals to activate β2 integrins in neutrophilsQ88204080
L-selectin mechanochemistry restricts neutrophil priming in vivo.Q30851884
The epidemiology of venous thromboembolism in the communityQ33865646
Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter miceQ33927482
E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rollingQ34033865
Mechanistic view of risk factors for venous thromboembolismQ34255409
von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse modelsQ34666946
Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.Q35651662
Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injuryQ35760832
Critical review of mouse models of venous thrombosisQ35796005
P-selectin promotes neutrophil extracellular trap formation in miceQ35836873
O-glycans direct selectin ligands to lipid rafts on leukocytes.Q35865559
Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.Q35894194
Blocking neutrophil integrin activation prevents ischemia-reperfusion injuryQ35894364
New insights into the mechanisms of venous thrombosisQ36068279
Selectins: initiators of leucocyte adhesion and signalling at the vascular wallQ36117363
Multi-Inhibitory Effects of A2A Adenosine Receptor Signaling on Neutrophil Adhesion Under FlowQ36119376
Intracellular signalling controlling integrin activation in lymphocytesQ36167584
Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flowQ36843799
Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivoQ36851924
Compartmentalization of ITAM and integrin signaling by adapter moleculesQ36877284
How chemokines invite leukocytes to danceQ37246681
Activated platelets signal chemokine synthesis by human monocytesQ37353355
The ins and outs of leukocyte integrin signalingQ37419383
Role of selectins and fibrinolysis in VTE.Q37419804
Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritisQ37424722
Rolling cell adhesionQ37540219
Neutrophil arrest by LFA-1 activationQ38018949
The post thrombotic syndrome: Ignore it and it will come back to bite you.Q38606248
In Vivo Role of Neutrophil Extracellular Traps in Antiphospholipid Antibody-Mediated Venous ThrombosisQ39328138
Functional complementation of BLNK by SLP-76 and LAT linker proteinsQ40863036
Chemokines and the signaling modules regulating integrin affinityQ42177472
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in miceQ42355573
Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in MiceQ42368510
Importance of primary capture and L-selectin-dependent secondary capture in leukocyte accumulation in inflammation and atherosclerosis in vivo.Q42944436
Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76.Q43152094
The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice.Q46463601
P433issue13
P921main subjectdeep vein thrombosisQ1762339
P304page(s)1426-1437
P577publication date2018-08-01
P1433published inBloodQ885070
P1476titleCooperative PSGL-1 and CXCR2 signaling in neutrophils promotes deep vein thrombosis in mice
P478volume132

Reverse relations

cites work (P2860)
Q97676619Chronic ethanol consumption compromises neutrophil function in acute pulmonary Aspergillus fumigatus infection
Q60907233Endothelial signaling by neutrophil-released oncostatin M enhances P-selectin–dependent inflammation and thrombosis
Q90093923Extracellular DNA NET-Works With Dire Consequences for Health
Q89739695Histamine deficiency facilitates coronary microthrombosis after myocardial infarction by increasing neutrophil-platelet interactions
Q99558038Immune responses during COVID-19 infection
Q94474151In vivo evidence for extracellular DNA trap formation
Q90204334LncRNA GUSBP5-AS promotes EPC migration and angiogenesis and deep vein thrombosis resolution by regulating FGF2 and MMP2/9 through the miR-223-3p/FOXO1/Akt pathway
Q98177671Multiple Roles for Chemokines in Neutrophil Biology
Q58606442The role of CXCR2 in acute inflammatory responses and its antagonists as anti-inflammatory therapeutics

Search more.