Appraisal of Non-Cardiovascular Safety for Sodium-Glucose Co-Transporter 2 Inhibitors: A Systematic Review and Meta-Analysis of Placebo-Controlled Randomized Clinical Trials

scientific article published on 19 September 2019

Appraisal of Non-Cardiovascular Safety for Sodium-Glucose Co-Transporter 2 Inhibitors: A Systematic Review and Meta-Analysis of Placebo-Controlled Randomized Clinical Trials is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3389/FPHAR.2019.01066
P932PMC publication ID6764217
P698PubMed publication ID31616297

P50authorHao LiQ85595530
P2093author name stringXiao-Yan Liu
Jing Ma
Zhen Zhang
Hou-Wen Lin
Yi-Hong Jiang
Long Shen
Zhi-Chun Gu
Yao-Min Hu
Fang-Hong Shi
P2860cites workGlobal, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015Q27468570
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Meta-Analysis of Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Cardiovascular Outcomes and All-Cause Mortality Among Patients With Type 2 Diabetes MellitusQ30245104
Effects of sodium-glucose co-transporter 2 (SGLT2) inhibition on renal function and albuminuria in patients with type 2 diabetes: a systematic review and meta-analysisQ32186373
Osmotic diuresis with SGLT2 inhibition: analysis of events related to volume reduction in dapagliflozin clinical trialsQ33166813
Effects of SGLT2 inhibitors on UTIs and genital infections in type 2 diabetes mellitus: a systematic review and meta-analysisQ33767478
Novel oral glucose-lowering drugs are associated with lower risk of all-cause mortality, cardiovascular events and severe hypoglycaemia compared with insulin in patients with type 2 diabetesQ33835709
Global Economic Burden of Diabetes in Adults: Projections From 2015 to 2030.Q51767622
Lower Cardiovascular Risk Associated with SGLT-2i in >400,000 Patients: The CVD-REAL 2 Study.Q52655573
SGLT-2 inhibitors and the risk of infections: a systematic review and meta-analysis of randomized controlled trials.Q54266015
Clinical adverse effects of sodium-glucose cotransporter 2 inhibitors: Protocol for a systematic review and meta-analysisQ58789064
Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular disease, death and safety outcomes in type 2 diabetes - A systematic reviewQ88233662
SGLT2 inhibitors and the kidney: Effects and mechanismsQ89125399
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Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 DiabetesQ34673134
Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: a systematic review and meta-analysis.Q35968414
Diabetic Ketoacidosis and Related Events in the Canagliflozin Type 2 Diabetes Clinical ProgramQ35973246
Euglycemic Diabetic Ketoacidosis: A Potential Complication of Treatment With Sodium-Glucose Cotransporter 2 InhibitionQ35973255
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Canagliflozin and Cardiovascular and Renal Events in Type 2 DiabetesQ38729780
Sodium-glucose co-transporter-2 inhibitors and risk of adverse renal outcomes among patients with type 2 diabetes: A network and cumulative meta-analysis of randomized controlled trials.Q38940175
Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projectionsQ39474763
Effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors on serum uric acid level: A meta-analysis of randomized controlled trialsQ40068172
Urinary tract and genital infections in patients with type 2 diabetes treated with sodium-glucose co-transporter 2 inhibitors: A meta-analysis of randomized controlled trialsQ40445386
Acute renal failure with sodium-glucose-cotransporter-2 inhibitors: Analysis of the FDA adverse event report system databaseQ47366627
Cardiovascular Safety, Long-Term Noncardiovascular Safety, and Efficacy of Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus: A Systemic Review and Meta-Analysis With Trial Sequential AnalysisQ47652080
Lower Risk of Death With SGLT2 Inhibitors in Observational Studies: Real or Bias?Q48374438
Effects of SGLT-2 inhibitors on diabetic ketoacidosis: A meta-analysis of randomised controlled trials.Q48599312
Sodium-glucose co-transporter 2 inhibitors and cardiovascular outcomes: A systematic review and meta-analysis.Q49668043
8. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2018.Q49988613
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectplaceboQ269829
P304page(s)1066
P577publication date2019-09-19
P1433published inFrontiers in PharmacologyQ2681208
P1476titleAppraisal of Non-Cardiovascular Safety for Sodium-Glucose Co-Transporter 2 Inhibitors: A Systematic Review and Meta-Analysis of Placebo-Controlled Randomized Clinical Trials
P478volume10

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Q90043452Basic and Clinical Pharmaco-Therapeutics of SGLT2 Inhibitors: A Contemporary Updatecites workP2860

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