| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Deanna L Benson | |
| George W Huntley | |||
| P2860 | cites work | Altered reward-related neural responses in non-manifesting carriers of the Parkinson disease related LRRK2 mutation | Q57177264 |
| Structural determinants of ion flow through recombinant glutamate receptor channels | Q57378348 | ||
| Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4 | Q58111473 | ||
| Network abnormalities among non-manifesting Parkinson disease related LRRK2 mutation carriers | Q64779218 | ||
| Are we listening to everything the PARK genes are telling us? | Q64782437 | ||
| Dopamine D2 receptor activation potently inhibits striatal glutamatergic transmission in a G2019S LRRK2 genetic model of Parkinson's disease | Q64866830 | ||
| Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood. | Q64911660 | ||
| Presynaptic origins of distinct modes of neurotransmitter release | Q88216673 | ||
| Repeated social defeat in female mice induces anxiety-like behavior associated with enhanced myelopoiesis and increased monocyte accumulation in the brain | Q91233861 | ||
| Management of Depression in Parkinson's Disease: A Systematic Review | Q92582995 | ||
| LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool | Q24292798 | ||
| Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease | Q24294458 | ||
| LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis | Q24299176 | ||
| Kinase activity of mutant LRRK2 mediates neuronal toxicity | Q24303603 | ||
| LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism | Q24309509 | ||
| LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity | Q24323196 | ||
| LRRK2 regulates synaptic vesicle endocytosis | Q24336523 | ||
| Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice | Q27308060 | ||
| Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B(-/-) mice | Q27311527 | ||
| Crystal structures of a Rab protein in its inactive and active conformations | Q27628708 | ||
| Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies | Q27686837 | ||
| Parkinson's disease: animal models and dopaminergic cell vulnerability | Q28080503 | ||
| Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases | Q28119192 | ||
| Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology | Q28131833 | ||
| Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease | Q28292932 | ||
| Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons | Q28363018 | ||
| Functional compartmentalization of endosomal trafficking for the synaptic delivery of AMPA receptors during long-term potentiation | Q28568192 | ||
| The mGluR theory of fragile X mental retardation | Q29615060 | ||
| Kinase activity is required for the toxic effects of mutant LRRK2/dardarin | Q29620478 | ||
| The many faces of CREB | Q29622920 | ||
| Dichotomous dopaminergic control of striatal synaptic plasticity | Q30493521 | ||
| Acquisition and performance of goal-directed instrumental actions depends on ERK signaling in distinct regions of dorsal striatum in rats. | Q30493858 | ||
| Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors | Q30495714 | ||
| Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease | Q33614776 | ||
| Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents | Q33825413 | ||
| DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses | Q33955033 | ||
| An essay on the shaking palsy. 1817. | Q33958859 | ||
| Exaggerated translation causes synaptic and behavioural aberrations associated with autism | Q34319260 | ||
| Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging | Q34325540 | ||
| Depression and subsequent risk of Parkinson disease: A nationwide cohort study | Q34477187 | ||
| Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress | Q34526470 | ||
| Psychiatric aspects of Parkinson's disease | Q34574771 | ||
| The Retromer Supports AMPA Receptor Trafficking During LTP. | Q51068763 | ||
| Executive function differences in multiple system atrophy and Parkinson's disease. | Q52108379 | ||
| The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human. | Q55265334 | ||
| LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory | Q42467623 | ||
| Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models | Q42508054 | ||
| Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia | Q44383212 | ||
| Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease. | Q46755822 | ||
| Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. | Q47142767 | ||
| Rab29 activation of the Parkinson's disease-associated LRRK2 kinase | Q47150726 | ||
| LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network | Q47362838 | ||
| LRRK2 G2019S induces anxiety/depression-like behavior prior to the onset of motor dysfunction with 5-HT1A receptor upregulation in mice | Q47557364 | ||
| The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning. | Q47565456 | ||
| Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons. | Q47621902 | ||
| Hyperactivity and lack of social discrimination in the adolescent Fmr1 knockout mouse. | Q47680084 | ||
| NEURODEVELOPMENT. Adult cortical plasticity depends on an early postnatal critical period | Q48077574 | ||
| Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses | Q48100653 | ||
| (G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse | Q48294256 | ||
| Psychiatric diseases predated the occurrence of Parkinson disease: a retrospective cohort study | Q48364481 | ||
| Postnatal development of the rat neostriatum: electrophysiological, light- and electron-microscopic studies | Q48417740 | ||
| Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N. | Q48449821 | ||
| Postnatal development of excitatory synaptic input to the rat neostriatum: an electron microscopic study | Q48474988 | ||
| Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation | Q48596002 | ||
| Identification of a site in glutamate receptor subunits that controls calcium permeability | Q48669947 | ||
| Altered serotonin metabolism in depressed patients with parkinson's disease | Q48680548 | ||
| Bidirectional and long-lasting control of alcohol-seeking behavior by corticostriatal LTP and LTD. | Q50055065 | ||
| Expression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice | Q34723024 | ||
| Reorganization of corticostriatal circuits in healthy G2019S LRRK2 carriers | Q35106295 | ||
| A standardized protocol for repeated social defeat stress in mice. | Q35561938 | ||
| Stress, depression and Parkinson's disease | Q35713356 | ||
| The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus | Q35941370 | ||
| Recurrent network activity drives striatal synaptogenesis | Q36009922 | ||
| Decreased probability of neurotransmitter release underlies striatal long-term depression and postnatal development of corticostriatal synapses | Q36054269 | ||
| Lower cognitive performance in healthy G2019S LRRK2 mutation carriers | Q36198611 | ||
| LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function | Q36581417 | ||
| The role of the dorsal striatum in reward and decision-making | Q36899759 | ||
| Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease | Q36931043 | ||
| Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S Mutation | Q37080018 | ||
| LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction | Q37124577 | ||
| Striatal plasticity and basal ganglia circuit function | Q37336143 | ||
| Anatomic and molecular development of corticostriatal projection neurons in mice | Q37464509 | ||
| LRRK2: cause, risk, and mechanism | Q37635000 | ||
| Genetic animal models of Parkinson's disease | Q37765030 | ||
| When does Parkinson disease start? | Q37772029 | ||
| The role of innate and adaptive immunity in Parkinson's disease | Q38166155 | ||
| Investigating habits: strategies, technologies and models | Q38191593 | ||
| β-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat | Q38254940 | ||
| Deregulation of protein translation control, a potential game-changing hypothesis for Parkinson's disease pathogenesis. | Q38532397 | ||
| Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease | Q38553874 | ||
| LRRK2 mouse models: dissecting the behavior, striatal neurochemistry and neurophysiology of PD pathogenesis | Q39137331 | ||
| LRRK2 and the Immune System | Q39206438 | ||
| Neural Substrates of Depression and Resilience | Q39233337 | ||
| Nucleus accumbens medium spiny neuron subtypes mediate depression-related outcomes to social defeat stress | Q39268133 | ||
| Non-motor features of Parkinson disease | Q39358549 | ||
| Neural correlates of executive functions in healthy G2019S LRRK2 mutation carriers | Q39477657 | ||
| Endocannabinoid-Mediated Plasticity in Nucleus Accumbens Controls Vulnerability to Anxiety after Social Defeat Stress. | Q39565581 | ||
| Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release | Q40633643 | ||
| Abberant protein synthesis in G2019S LRRK2 Drosophila Parkinson disease-related phenotypes | Q41279255 | ||
| Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq | Q41335062 | ||
| Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice. | Q41978493 | ||
| LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts. | Q42005064 | ||
| Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice | Q42268862 | ||
| LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate | Q42288293 | ||
| Long-term synaptic depression in the striatum: physiological and pharmacological characterization | Q42453585 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | Parkinson's disease | Q11085 |
| P304 | page(s) | 265 | |
| P577 | publication date | 2020-03-26 | |
| P1433 | published in | Frontiers in Neuroscience | Q2177807 |
| P1476 | title | Origins of Parkinson's Disease in Brain Development: Insights From Early and Persistent Effects of LRRK2-G2019S on Striatal Circuits | |
| P478 | volume | 14 |
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