The Isolation of New Pore-Forming Toxins from the Sea Anemone Actinia fragacea Provides Insights into the Mechanisms of Actinoporin Evolution

scientific article published on 10 July 2019

The Isolation of New Pore-Forming Toxins from the Sea Anemone Actinia fragacea Provides Insights into the Mechanisms of Actinoporin Evolution is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/TOXINS11070401
P932PMC publication ID6669745
P698PubMed publication ID31295915

P50authorKoldo MoranteQ57447750
Ana Rosa VigueraQ31855381
P2093author name stringKouhei Tsumoto
Jose M M Caaveiro
Augusto Bellomio
Juan Manuel González-Mañas
P2860cites workNon-Darwinian EvolutionQ7048737
BLAST+: architecture and applicationsQ21284368
Slightly Deleterious Mutant Substitutions in EvolutionQ22122425
Evolutionary Rate at the Molecular LevelQ22122432
Gapped BLAST and PSI-BLAST: a new generation of protein database search programsQ24545170
Thermodynamic prediction of protein neutralityQ24557480
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Sea anemone (Cnidaria, Anthozoa, Actiniaria) toxins: an overviewQ26825180
Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offsQ27639212
Intrinsic local disorder and a network of charge-charge interactions are key to actinoporin membrane disruption and cytotoxicityQ27667196
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approachQ27860716
Overview of the CCP4 suite and current developmentsQ27860782
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal OmegaQ27860809
Phasercrystallographic softwareQ27860930
Purification, cloning and characterization of fragaceatoxin C, a novel actinoporin from the sea anemone Actinia fragacea.Q50589796
Osmotically driven prey disintegration in the gastrovascular cavity of the green hydra by a pore-forming protein.Q50670805
Haemolytic actinoporins interact with carbohydrates using their lipid-binding module.Q50935628
Multigene Family of Pore-Forming Toxins from Sea Anemone Heteractis crispa.Q55492498
MEGA X: Molecular Evolutionary Genetics Analysis across Computing PlatformsQ61632286
Immunohistochemical targeting of sea anemone cytolysins on tentacles, mesenteric filaments and isolated nematocysts of Stichodactyla helianthusQ82353235
Refinement of macromolecular structures by the maximum-likelihood methodQ27861011
Features and development of CootQ27861079
Scaling and assessment of data qualityQ27861107
Phylogeny-aware gap placement prevents errors in sequence alignment and evolutionary analysisQ28284481
ProtTest 3: fast selection of best-fit models of protein evolutionQ29547651
Deciphering key features in protein structures with the new ENDscript serverQ29617219
Structural determinants of the rate of protein evolution in yeast.Q30354999
Understanding protein non-folding.Q30385084
Identification of a Membrane-bound Prepore Species Clarifies the Lytic Mechanism of ActinoporinsQ30390842
Structural basis for self-assembly of a cytolytic pore lined by protein and lipidQ30625306
ConSurf: an algorithmic tool for the identification of functional regions in proteins by surface mapping of phylogenetic informationQ32181106
webPRANK: a phylogeny-aware multiple sequence aligner with interactive alignment browserQ33756736
Role of conservative mutations in protein multi-property adaptationQ33956067
Stability effects of mutations and protein evolvabilityQ34019441
A Protein SequenatorQ34054588
Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actiniaria).Q34100019
Extensive and continuous duplication facilitates rapid evolution and diversification of gene familiesQ34160034
Complex cocktails: the evolutionary novelty of venomsQ34316019
Missense meanderings in sequence space: a biophysical view of protein evolutionQ34439602
Three-dimensional structure of the actinoporin sticholysin I. Influence of long-distance effects on protein function.Q34572784
The stability effects of protein mutations appear to be universally distributedQ34625806
Revealing Assembly of a Pore-Forming Complex Using Single-Cell Kinetic Analysis and Modeling.Q36804169
Evolution of the Cytolytic Pore-Forming Proteins (Actinoporins) in Sea Anemones.Q37543612
Cytolytic proteins from cnidarians - an overviewQ38141686
A pore-forming toxin requires a specific residue for its activity in membranes with particular physicochemical properties.Q39944610
Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin from Actinia fragacea.Q40813866
Evolution of an ancient venom: recognition of a novel family of cnidarian toxins and the common evolutionary origin of sodium and potassium neurotoxins in sea anemoneQ41252629
Synergistic Action of Actinoporin Isoforms from the Same Sea Anemone Species Assembled into Functionally Active HeteroporesQ41908533
Metal-binding dependent disruption of membranes by designed helicesQ41922468
A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization.Q42104949
Relation between protein stability, evolution and structure, as probed by carboxylic acid mutations.Q44751753
One single salt bridge explains the different cytolytic activities shown by actinoporins sticholysin I and II from the venom of Stichodactyla helianthusQ47402567
Alpha-Helical Fragaceatoxin C Nanopore Engineered for Double-Stranded and Single-Stranded Nucleic Acid Analysis.Q48364366
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P921main subjectStrawberry anemoneQ2105618
P577publication date2019-07-10
P1433published inToxinsQ15724569
P1476titleThe Isolation of New Pore-Forming Toxins from the Sea Anemone Actinia fragacea Provides Insights into the Mechanisms of Actinoporin Evolution
P478volume11

Search more.