Understanding protein non-folding.

scientific article

Understanding protein non-folding. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.BBAPAP.2010.01.017
P932PMC publication ID2882790
P698PubMed publication ID20117254
P5875ResearchGate publication ID41190343

P50authorVladimir N. UverskyQ59698496
P2093author name stringA Keith Dunker
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The molten globule state of alpha-lactalbumin.Q40949095
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Part II: alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease.Q35157623
Polymeric aspects of protein folding: a brief overviewQ35181367
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Shattuck lecture--neurodegenerative diseases and prionsQ28189500
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Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarraysQ28235146
Intermediates in the folding reactions of small proteinsQ28249972
TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancerQ28256844
Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å ResolutionQ28257008
Analysis of molecular recognition features (MoRFs)Q28260253
Distinct and opposite activities of human terminal deoxynucleotidyltransferase splice variantsQ28281082
Structure of myoglobin: A three-dimensional Fourier synthesis at 2 A. resolutionQ28300138
p53 mutations in human cancersQ28302973
Activation and activities of the p53 tumour suppressor proteinQ28366563
Aberrant mobility phenomena of the DNA repair protein XPAQ28367384
The importance of intrinsic disorder for protein phosphorylationQ28776125
Positive selection on protein-length in the evolution of a primate sperm ion channelQ28776836
The 'molten globule' state is involved in the translocation of proteins across membranes?Q54740420
Kinetic and equilibrium folding intermediatesQ57137268
Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53Q57650265
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Evaluation of disorder predictions in CASP5Q57972076
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Accuracy of protein flexibility predictionsQ58533574
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Three-dimensional structure of an antigen–antibody complex at 6 Å resolutionQ59081477
The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, σ28Q59210031
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Sequence Data Analysis for Long Disordered Regions Prediction in the Calcineurin FamilyQ73174366
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Predicting Protein Disorder for N-, C-, and Internal RegionsQ73174432
Predicting Binding Regions within Disordered ProteinsQ73174434
Solution structure of native proteins with irregular folds from Raman optical activityQ73227985
Sulfur and selenium: the role of oxidation state in protein structure and functionQ35561098
The molten globule intermediate for protein insertion or translocation through membranesQ35632874
Intrinsic disorder and functional proteomicsQ35632957
Inhibition of the p53-MDM2 interaction: targeting a protein-protein interface.Q35646494
Osmotic stress, crowding, preferential hydration, and binding: A comparison of perspectivesQ35667882
A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures.Q35669656
Splice variants of G protein-coupled receptorsQ35679333
Conformational constraints for amyloid fibrillation: the importance of being unfoldedQ35768731
Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosisQ35818770
The role of structural disorder in the function of RNA and protein chaperonesQ35850848
Keeping dry and crossing membranesQ35876049
Targeting the p53-MDM2 interaction to treat cancerQ35903526
iPDA: integrated protein disorder analyzerQ35914230
How did alternative splicing evolve?Q35930718
Aberrant and alternative splicing in cancerQ35936123
Quantitative characterization of intrinsic disorder in polyglutamine: insights from analysis based on polymer theoriesQ35963371
Natively unfolded proteinsQ36046424
Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signalingQ36226283
Assessing protein disorder and induced foldingQ36312787
Pre-structured motifs in the natively unstructured preS1 surface antigen of hepatitis B virusQ36389609
Characterizing residual structure in disordered protein States using nuclear magnetic resonance.Q36587216
Identification of intrinsic order and disorder in the DNA repair protein XPA.Q36640580
Atomic-level characterization of disordered protein ensemblesQ36717589
Non-globular domains in protein sequences: automated segmentation using complexity measuresQ36726009
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfoldedQ36830682
Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stressQ36896224
Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regionsQ36986347
The interface of protein-protein complexes: analysis of contacts and prediction of interactionsQ37031953
TOP-IDP-scale: a new amino acid scale measuring propensity for intrinsic disorderQ37178764
CDF it all: consensus prediction of intrinsically disordered proteins based on various cumulative distribution functionsQ37195737
Crystallography and protein-protein interactions: biological interfaces and crystal contacts.Q37330481
Protein disorder is positively correlated with gene expression in Escherichia coliQ37369375
Biophysical characterization of intrinsically disordered proteinsQ37375367
Formation of a yeast SNARE complex is accompanied by significant structural changesQ28909278
Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversityQ28910326
p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein foldingQ28910366
Intrinsic structural disorder and sequence features of the cell cycle inhibitor p57Kip2Q28910370
Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor FosQ28910425
Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structureQ28910456
Lethality and centrality in protein networksQ29547267
Intrinsically unstructured proteinsQ29614784
Protein disorder prediction: implications for structural proteomicsQ29615736
GlobPlot: Exploring protein sequences for globularity and disorderQ29615737
Why are "natively unfolded" proteins unstructured under physiologic conditions?Q29615739
Intrinsically unstructured proteins: re-assessing the protein structure-function paradigmQ29615865
IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy contentQ29615888
Intrinsic disorder and protein functionQ29616415
Natively unfolded proteins: a point where biology waits for physicsQ29616416
Coupling of folding and binding for unstructured proteinsQ29616417
Sequence complexity of disordered proteinQ29616420
Small-molecule inhibitors of protein-protein interactions: progressing towards the dreamQ29617758
Biophysical and molecular mechanisms of Shaker potassium channel inactivationQ29617879
Why genes in pieces?Q29618207
Alternative splicing: increasing diversity in the proteomic worldQ29618730
Structural polymorphism and multifunctionality of myelin basic proteinQ30157180
Local structural disorder imparts plasticity on linear motifs.Q30158016
Biological activity and pathological implications of misfolded proteins.Q30322243
Zn(2+)-mediated structure formation and compaction of the "natively unfolded" human prothymosin alpha.Q30325994
Biophysical constraints for protein structure prediction.Q30332629
Comparing and combining predictors of mostly disordered proteins.Q30350136
The interplay between structure and function in intrinsically unstructured proteins.Q30350853
Exploiting heterogeneous sequence properties improves prediction of protein disorder.Q30351476
Flexible nets. The roles of intrinsic disorder in protein interaction networks.Q30351593
Length-dependent prediction of protein intrinsic disorder.Q30353929
Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediateQ30354885
Spritz: a server for the prediction of intrinsically disordered regions in protein sequences using kernel machines.Q30355526
Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.Q30360720
Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.Q30360723
Protein structure protection commits gene expression patterns.Q30370464
The unfoldomics decade: an update on intrinsically disordered proteins.Q30372413
To be folded or to be unfolded?Q43105053
Cytosol has a small effect on protein backbone dynamicsQ43153021
Protein dynamics in living cellsQ43153025
Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: conformational heterogeneity of alpha-synucleinQ43256880
NMR spin relaxation methods for characterization of disorder and folding in proteinsQ43623358
Alzheimer's disease in Down's syndrome: clinicopathologic studiesQ43697583
Single-molecule conformational dynamics of fluctuating noncovalent DNA-protein interactions in DNA damage recognition.Q43734511
Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposureQ43735123
Functional consequences of preorganized helical structure in the intrinsically disordered cell-cycle inhibitor p27(Kip1).Q43853836
Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small moleculesQ43945988
Scale-free networksQ44043429
VaZyMolO: a tool to define and classify modularity in viral proteinsQ44081701
Role of hydration in the binding of lac repressor to DNA.Q44179253
Is myelin basic protein crystallizable?Q44260610
Effect of zinc and temperature on the conformation of the gamma subunit of retinal phosphodiesterase: a natively unfolded proteinQ44366128
Splice variants: a homology modeling approachQ44745632
Alternative splicing in the N-terminus of Alzheimer's presenilin 1.Q45104033
Protein disk of tobacco mosaic virus at 2.8 A resolution showing the interactions within and between subunitsQ45381843
POODLE-L: a two-level SVM prediction system for reliably predicting long disordered regions.Q45965349
Anion-induced folding of Staphylococcal nuclease: characterization of multiple equilibrium partially folded intermediates.Q46010103
Hen egg white lysozyme fibrillation: a deep-UV resonance Raman spectroscopic study.Q46026899
Evidence for a partially folded intermediate in alpha-synuclein fibril formationQ46097239
Small-molecule perturbation of competing interactions between c-Myc and Max.Q46180274
Native and non-native conformation-specific antibodies directed to the loop region of hen egg-white lysozymeQ46226856
Lysozyme fibrillation: deep UV Raman spectroscopic characterization of protein structural transformationQ46552155
Structural and dynamic characterization of partially folded states of apomyoglobin and implications for protein foldingQ46559043
Uncovering the unfoldome: enriching cell extracts for unstructured proteins by acid treatmentQ46741729
A novel two-dimensional electrophoresis technique for the identification of intrinsically unstructured proteinsQ46751790
High-resolution macromolecular NMR spectroscopy inside living cellsQ46842119
Structure and stability of the molten globule state of guinea-pig alpha-lactalbumin: a hydrogen exchange studyQ46878009
Rational drug design via intrinsically disordered proteinQ47193604
Systematic study on crystal-contact engineering of diphthine synthase: influence of mutations at crystal-packing regions on X-ray diffraction qualityQ47287839
Use of fast protein size-exclusion liquid chromatography to study the unfolding of proteins which denature through the molten globuleQ47383646
Analysis of ordered and disordered protein complexes reveals structural features discriminating between stable and unstable monomersQ47609385
Preformed structural elements feature in partner recognition by intrinsically unstructured proteinsQ47692263
Flavors of protein disorderQ47700031
Intrinsic disorder in pathogenic and non-pathogenic microbes: discovering and analyzing the unfoldomes of early-branching eukaryotesQ47702038
Protein disorder and the evolution of molecular recognition: theory, predictions and observationsQ47715145
Thousands of proteins likely to have long disordered regions.Q47715178
Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc.Q47830329
Circular dichroism and optical rotatory dispersion of proteins and polypeptidesQ47906052
NMR structural studies of glutathione S-transferaseQ48007308
Coupled folding and binding with alpha-helix-forming molecular recognition elementsQ48122045
Prediction of disordered regions in proteins based on the meta approach.Q48347994
Evolutionary rate heterogeneity in proteins with long disordered regions.Q48626135
Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril proteinQ48634030
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.Q48691482
NMR observation of Tau in Xenopus oocytes.Q48760194
Preformed secondary structure drives the association reaction of GCN4-p1, a model coiled-coil systemQ73472065
Transient structure of the amyloid precursor protein cytoplasmic tail indicates preordering of structure for binding to cytosolic factorsQ73514351
The protein non-folding problem: amino acid determinants of intrinsic order and disorderQ73658941
A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell linesQ73910238
The C-terminal half of the anti-sigma factor FlgM contains a dynamic equilibrium solution structure favoring helical conformationsQ74137795
Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53Q74247134
A core-shell model of calcium phosphate nanoclusters stabilized by beta-casein phosphopeptides, derived from sedimentation equilibrium and small-angle X-ray and neutron-scattering measurementsQ74384645
All wrapped upQ74452382
[How many molten globules states exist?]Q77082683
Intrinsic protein disorder in complete genomesQ77145749
Comparing predictors of disordered proteinQ77145753
RELATIVE CONFORMATIONS OF SPERM WHALE METMYOGLOBIN AND APOMYOGLOBIN IN SOLUTIONQ77193419
Natively unfolded C-terminal domain of caldesmon remains substantially unstructured after the effective binding to calmodulinQ79319223
Role of intrinsic disorder in transient interactions of hub proteinsQ79416219
Inhibition of a protein-protein interaction between INI1 and c-Myc by small peptidomimetic molecules inspired by Helix-1 of c-Myc: identification of a new target of potential antineoplastic interestQ79535324
Abundance of intrinsic disorder in protein associated with cardiovascular diseaseQ80181937
Intrinsic disorder in yeast transcriptional regulatory networkQ80353265
Probing single-molecule protein conformational dynamicsQ80392008
RetractionQ80473843
POODLE-S: web application for predicting protein disorder by using physicochemical features and reduced amino acid set of a position-specific scoring matrixQ80545079
DPROT: prediction of disordered proteins using evolutionary informationQ81121706
Another window into disordered protein functionQ81239387
Prediction of unfolded segments in a protein sequence based on amino acid compositionQ81289447
Optimizing long intrinsic disorder predictors with protein evolutionary informationQ81484824
Intrinsic disorder prediction from the analysis of multiple protein fold recognition modelsQ81522495
Calmodulin signaling: analysis and prediction of a disorder-dependent molecular recognitionQ82627891
Biochemistry. Controlled chaosQ82752197
Disordered domains and high surface charge confer hubs with the ability to interact with multiple proteins in interaction networksQ82855583
Local flexibility in molecular function paradigmQ83005811
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectprotein foldingQ847556
P1104number of pages34
P304page(s)1231-1264
P577publication date2010-02-01
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleUnderstanding protein non-folding.
P478volume1804

Reverse relations

cites work (P2860)
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Q31019690Bayesian inference of protein ensembles from SAXS data
Q30155144Beta-barrel scaffold of fluorescent proteins: folding, stability and role in chromophore formation
Q34786728Beyond the random coil: stochastic conformational switching in intrinsically disordered proteins
Q33938679Binary classification of protein molecules into intrinsically disordered and ordered segments
Q27683664Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition
Q35001468Biochemical and structural studies of the oligomerization domain of the Nipah virus phosphoprotein: evidence for an elongated coiled-coil homotrimer
Q52649572Bioinformatic Analysis Reveals Conservation of Intrinsic Disorder in the Linker Sequences of Prokaryotic Dual-family Immunophilin Chaperones.
Q40200977Bioinformatical parsing of folding-on-binding proteins reveals their compositional and evolutionary sequence design
Q33834903Bioinformatics analysis of disordered proteins in prokaryotes
Q49329183Biophysical Evidence for Intrinsic Disorder in the C-terminal Tails of the Epidermal Growth Factor Receptor (EGFR) and HER3 Receptor Tyrosine Kinases.
Q38589803Biophysical Methods to Investigate Intrinsically Disordered Proteins: Avoiding an "Elephant and Blind Men" Situation
Q35780279Biophysical Studies on BEX3, the p75NTR-Associated Cell Death Executor, Reveal a High-Order Oligomer with Partially Folded Regions
Q89819908Bridging the Molecular-Cellular Gap in Understanding Ion Channel Clustering
Q26771372Can all heritable biology really be reduced to a single dimension?
Q33624448Cancer/Testis Antigens: "Smart" Biomarkers for Diagnosis and Prognosis of Prostate and Other Cancers
Q42850704Cancer: tilting at windmills?
Q35192392Catalytically active alkaline molten globular enzyme: Effect of pH and temperature on the structural integrity of 5-aminolevulinate synthase
Q37398192Caulobacter PopZ forms an intrinsically disordered hub in organizing bacterial cell poles
Q56881082Celebrating structural biology
Q35193252Cell communication using intrinsically disordered proteins: what can syndecans say?
Q91892525Cell surface processing of the P1 adhesin of Mycoplasma pneumoniae identifies novel domains that bind host molecules
Q38597911Chain collapse of an amyloidogenic intrinsically disordered protein.
Q36747696Chaperone activation by unfolding
Q35036093Chaperoning roles of macromolecules interacting with proteins in vivo
Q43550120Characterisation of an intrinsically disordered protein complex of Swi5-Sfr1 by ion mobility mass spectrometry and small-angle X-ray scattering
Q45723415Characterization of UO2(2+) binding to osteopontin, a highly phosphorylated protein: insights into potential mechanisms of uranyl accumulation in bones
Q97692545Characterization of partially ordered states in the intrinsically disordered N-terminal domain of p53 using millisecond molecular dynamics simulations
Q34787399Characterization of the interactions between the nucleoprotein and the phosphoprotein of Henipavirus
Q55025251Classification of Complete Proteomes of Different Organisms and Protein Sets Based on Their Protein Distributions in Terms of Some Key Attributes of Proteins.
Q22061736Classification of intrinsically disordered regions and proteins
Q24597526Coherent Behavior and the Bound State of Water and K(+) Imply Another Model of Bioenergetics: Negative Entropy Instead of High-energy Bonds
Q28483979Common features at the start of the neurodegeneration cascade
Q47676441Common molecular pathogenesis of disease-related intrinsically disordered proteins revealed by NMR analysis
Q50586986Compact tomato seedlings and plants upon overexpression of a tomato chromatin remodelling ATPase gene.
Q35494059Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge
Q28543617Comparison of amino acids physico-chemical properties and usage of late embryogenesis abundant proteins, hydrophilins and WHy domain
Q30399040Comparison of the intrinsic disorder propensities of the RuBisCO activase enzyme from the motile and non-motile oceanic green microalgae
Q40162990Compartmentalization and Functionality of Nuclear Disorder: Intrinsic Disorder and Protein-Protein Interactions in Intra-Nuclear Compartments
Q34060169Competing views on cancer
Q47121438Comprehensive analysis of the dynamic structure of nuclear localization signals
Q35034116Comprehensive repertoire of foldable regions within whole genomes
Q34499971Computational Identification of MoRFs in Protein Sequences Using Hierarchical Application of Bayes Rule
Q34295598Computational analysis of position-dependent disorder content in DisProt database
Q28483769Computational and statistical analyses of amino acid usage and physico-chemical properties of the twelve late embryogenesis abundant protein classes
Q35193908Computational design of a pH stable enzyme: understanding molecular mechanism of penicillin acylase's adaptation to alkaline conditions
Q35619593Computational prediction of protein-protein interactions
Q33875537Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function
Q28397659Conformational Entropy of Intrinsically Disordered Proteins from Amino Acid Triads
Q36068293Conformational Stability of the NH2-Terminal Propeptide of the Precursor of Pulmonary Surfactant Protein SP-B.
Q42320832Conformational heterogeneity and intrinsic disorder in enzyme regulation: Glucokinase as a case study
Q64071818Conserved Glycines Control Disorder and Function in the Cold-Regulated Protein, COR15A
Q34390409Conserved RNA helicase FRH acts nonenzymatically to support the intrinsically disordered neurospora clock protein FRQ.
Q37808397Converting a protein into a switch for biosensing and functional regulation
Q24632917Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin
Q40108886Correlating Flavivirus virulence and levels of intrinsic disorder in shell proteins: protective roles vs. immune evasion
Q41157300Crystallization and preliminary X-ray diffraction analysis of two peptides from Alzheimer PHF in complex with the MN423 antibody Fab fragment.
Q47561686Current Advances in Aptamers for Cancer Diagnosis and Therapy
Q28291067DNA mismatch repair in eukaryotes and bacteria
Q46944365DRM1 and DRM2 expression regulation: potential role of splice variants in response to stress and environmental factors in Arabidopsis.
Q38724766Dancing Protein Clouds: The Strange Biology and Chaotic Physics of Intrinsically Disordered Proteins
Q98196791De novo engineering of intracellular condensates using artificial disordered proteins
Q38269075De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics
Q35940252Deciphering Mode of Action of Functionally Important Regions in the Intrinsically Disordered Paxillin (Residues 1-313) Using Its Interaction with FAT (Focal Adhesion Targeting Domain of Focal Adhesion Kinase).
Q52593130Deciphering the dark proteome of Chikungunya virus.
Q39148669Deciphering the mechanisms of binding induced folding at nearly atomic resolution: The Φ value analysis applied to IDPs
Q38223691Detecting selection on protein stability through statistical mechanical models of folding and evolution
Q42144732Detection and characterization of megasatellites in orthologous and nonorthologous genes of 21 fungal genomes
Q36102373Determinants of exon-level evolutionary rates in Arabidopsis species
Q36275962Deuterium isotope shifts for backbone ¹H, ¹⁵N and ¹³C nuclei in intrinsically disordered protein α-synuclein
Q58798900Diel rewiring and positive selection of ancient plant proteins enabled evolution of CAM photosynthesis in Agave
Q42119193Differential dehydration effects on globular proteins and intrinsically disordered proteins during film formation
Q30402101Digested disorder: Quarterly intrinsic disorder digest (April-May-June, 2013).
Q22061724Digested disorder: Quarterly intrinsic disorder digest (January/February/March, 2013).
Q39148653Digested disorder: Quarterly intrinsic disorder digest (July-August-September, 2013)
Q41846623Dihedral-based segment identification and classification of biopolymers I: proteins
Q39578401Dimension conversion and scaling of disordered protein chains
Q40717838Direct evidence that the carboxyl-terminal sequence of a bacterial chemoreceptor is an unstructured linker and enzyme tether.
Q28550591DisPredict: A Predictor of Disordered Protein Using Optimized RBF Kernel
Q47701746Discovery of Cryoprotective Activity in Human Genome-Derived Intrinsically Disordered Proteins
Q30422189Disease-associated mutations disrupt functionally important regions of intrinsic protein disorder
Q38779717Disorder in the lifetime of a protein
Q53106730Disorder, Promiscuous Interactions, and Stochasticity Regulate State Switching in the Unstable Prostate.
Q28083580Disorder-to-order transition in the CyaA toxin RTX domain: implications for toxin secretion
Q28652765Disordered proteinaceous machines
Q38288151Dissecting physical structure of calreticulin, an intrinsically disordered Ca2+-buffering chaperone from endoplasmic reticulum
Q38779742Distribution and cluster analysis of predicted intrinsically disordered protein Pfam domains
Q36043844Distribution of Pico- and Nanosecond Motions in Disordered Proteins from Nuclear Spin Relaxation
Q88962442Does water stress promote the proteome-wide adjustment of intrinsically disordered proteins in plants?
Q57128184Drawing on disorder: How viruses use histone mimicry to their advantage
Q28732341Drug design for ever, from hype to hope
Q30399262Dynamic New World: Refining Our View of Protein Structure, Function and Evolution
Q30155295Dynamic association of BAM complex modules includes surface exposure of the lipoprotein BamC.
Q89535892Dynamic conformational flexibility and molecular interactions of intrinsically disordered proteins
Q38340554Dynamic interactions between clathrin and locally structured elements in a disordered protein mediate clathrin lattice assembly
Q50472416Dynamics of the intrinsically disordered protein CP12 in its association with GAPDH in the green alga Chlamydomonas reinhardtii: a fuzzy complex.
Q50451264Dynamics of vacuoles and H+-pyrophosphatase visualized by monomeric green fluorescent protein in Arabidopsis: artifactual bulbs and native intravacuolar spherical structures.
Q31029065ELM 2016--data update and new functionality of the eukaryotic linear motif resource
Q57299966Effect of an Intrinsically Disordered Plant Stress Protein on the Properties of Water
Q30392544Effect of natural polymorphism on structure and function of the Yersinia pestis outer membrane porin F (OmpF protein): a computational study
Q86275590Effect of temperature on the conformation of natively unfolded protein 4E-BP1 in aqueous and mixed solutions containing trifluoroethanol and hexafluoroisopropanol
Q28594349Effects of HMGN variants on the cellular transcription profile
Q30404253Effects of the regulatory ligands calcium and GTP on the thermal stability of tissue transglutaminase
Q48296879Efficient Gene Transfection through Inhibition of β-Sheet (Amyloid Fiber) Formation of a Short Amphiphilic Peptide by Gold Nanoparticles
Q39005050Erythropoietin and co.: intrinsic structure and functional disorder
Q91794503Estimation of Flexible and Rigid Residues of Disulfide-Bridged and Phosphorylated Proteins Using Matrix-Assisted Laser Desorption/Ionization in-Source Decay Mass Spectrometry
Q30392517Estimation of Position Specific Energy as a Feature of Protein Residues from Sequence Alone for Structural Classification
Q43029316Evidence for multiple group 1 late embryogenesis abundant proteins in encysted embryos of Artemia and their organelles
Q58697064Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery
Q36254589Evolutionarily Conserved Sequence Features Regulate the Formation of the FG Network at the Center of the Nuclear Pore Complex
Q59051409Exact Solution to the Extended Zwanzig Model for Quasi-Sigmoidal Chemically Induced Denaturation Profiles: Specific Heat and Configurational Entropy
Q42211815Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life
Q30009908Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome
Q57905794Exploration of Conformational Spaces of High-Mannose-Type Oligosaccharides by an NMR-Validated Simulation
Q100444216Exploring Manually Curated Annotations of Intrinsically Disordered Proteins with DisProt
Q46305048Exploring disorder in the human charged biased proteins
Q27692089Exploring intrinsically disordered proteins using site-directed spin labeling electron paramagnetic resonance spectroscopy.
Q41220497Exploring the binding diversity of intrinsically disordered proteins involved in one-to-many binding
Q98292593Extended Experimental Inferential Structure Determination Method in Determining the Structural Ensembles of Disordered Protein States
Q38779757Extracting structural information from charge-state distributions of intrinsically disordered proteins by non-denaturing electrospray-ionization mass spectrometry
Q64098998Extreme Fuzziness: Direct Interactions between Two IDPs
Q35622155Fairy "tails": flexibility and function of intrinsically disordered extensions in the photosynthetic world
Q37312800Finding Our Way in the Dark Proteome
Q53165392First Aegean International Conference on Molecular Recognition.
Q27323967Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator
Q94569962Flexibility of intrinsically disordered degrons in AUX/IAA proteins reinforces auxin co-receptor assemblies
Q34321761Folding and binding of an intrinsically disordered protein: fast, but not 'diffusion-limited'.
Q39188880Folding factors and partners for the intrinsically disordered protein micro-exon gene 14 (MEG-14)
Q28730747Free cysteine modulates the conformation of human C/EBP homologous protein
Q47276758Functional Analysis of Human Hub Proteins and Their Interactors Involved in the Intrinsic Disorder-Enriched Interactions
Q55038891Functional and Structural Diversity of Acyl-coA Binding Proteins in Oil Crops.
Q27316805Functional diversity and structural disorder in the human ubiquitination pathway
Q30155121Functional fragments of disorder in outer membrane β barrel proteins
Q37502486Functional regulation of the SLC26-family protein prestin by calcium/calmodulin.
Q28085662Functional roles of transiently and intrinsically disordered regions within proteins
Q61038040Gene Birth Contributes to Structural Disorder Encoded by Overlapping Genes
Q45053413Genes encoding intrinsic disorder in Eukaryota have high GC content
Q31110949Genome-wide analysis of protein disorder in Arabidopsis thaliana: implications for plant environmental adaptation
Q34030755Global conformations of proteins as predicted from the modeling of their CZE mobility data
Q36100472Glutamine Synthetase Drugability beyond Its Active Site: Exploring Oligomerization Interfaces and Pockets.
Q90290699Harnessing biomolecular condensates in living cells
Q41098679High-resolution structural characterization of Noxa, an intrinsically disordered protein, by microsecond molecular dynamics simulations
Q30417432High-throughput characterization of intrinsic disorder in proteins from the Protein Structure Initiative
Q34717917Highly efficient NMR assignment of intrinsically disordered proteins: application to B- and T cell receptor domains
Q30009145Highly homologous proteins exert opposite biological activities by using different interaction interfaces
Q33973960Homogeneous and heterogeneous tertiary structure ensembles of amyloid-β peptides.
Q52309841How Robust Is the Mechanism of Folding-Upon-Binding for an Intrinsically Disordered Protein?
Q27676361How a single residue in individual β-thymosin/WH2 domains controls their functions in actin assembly
Q50540318How disorder influences order and vice versa--mutual effects in fusion proteins containing an intrinsically disordered and a globular protein.
Q38944980How disordered is my protein and what is its disorder for? A guide through the "dark side" of the protein universe
Q37902089How do dynamic cellular signals travel long distances?
Q34413996How does evolution tune biological noise?
Q50559161How to Predict Disorder in a Protein of Interest.
Q38779738Hypothesis: The unfolding power of protein dielectricity
Q38494386IDEAL in 2014 illustrates interaction networks composed of intrinsically disordered proteins and their binding partners
Q38426249IDEAL: Intrinsically Disordered proteins with Extensive Annotations and Literature
Q90010481IDPpi: Protein-Protein Interaction Analyses of Human Intrinsically Disordered Proteins
Q47608333Identification and Characterization of an Inside-Out Folding Intermediate of T4 Phage Sliding Clamp.
Q41965811Identification of Atg3 as an intrinsically disordered polypeptide yields insights into the molecular dynamics of autophagy-related proteins in yeast
Q36238139Identification of minimally interacting modules in an intrinsically disordered protein.
Q30419524Immobilization of proteins for single-molecule fluorescence resonance energy transfer measurements of conformation and dynamics
Q90324351Implementing efficient concerted rotations using Mathematica and C code⋆
Q53477774Improved prediction of residue flexibility by embedding optimized amino acid grouping into RSA-based linear models.
Q50864208In various protein complexes, disordered protomers have large per-residue surface areas and area of protein-, DNA- and RNA-binding interfaces.
Q47321952In vivo evidence for homo- and heterodimeric interactions of Arabidopsis thaliana dehydrins AtCOR47, AtERD10, and AtRAB18.
Q33935454In-silico prediction of disorder content using hybrid sequence representation
Q37132050Inactivation of the bacterial RNA polymerase due to acquisition of secondary structure by the ω subunit
Q36249966Increased phospholipase A2 activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein
Q34479883Induced fit, conformational selection and independent dynamic segments: an extended view of binding events
Q57093797Influenza virus infection causes global RNAPII termination defects
Q34162531Inherent structural disorder and dimerisation of murine norovirus NS1-2 protein
Q56983340Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme
Q42173191Insights into the coiled-coil organization of the Hendra virus phosphoprotein from combined biochemical and SAXS studies
Q41814829Interaction between the C-terminal domains of measles virus nucleoprotein and phosphoprotein: a tight complex implying one binding site
Q40058610Interaction of chemokine receptor CXCR4 in monomeric and dimeric state with its endogenous ligand CXCL12: coarse-grained simulations identify differences.
Q39378298Interactions of intrinsically disordered Thellungiella salsuginea dehydrins TsDHN-1 and TsDHN-2 with membranes - synergistic effects of lipid composition and temperature on secondary structure
Q41728638Intramolecular interactions stabilizing compact conformations of the intrinsically disordered kinase-inhibitor domain of Sic1: a molecular dynamics investigation.
Q55066708Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter.
Q47351608Intrinsic Disorder in Proteins with Pathogenic Repeat Expansions.
Q33292127Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction
Q36140744Intrinsic Disorder of the C-Terminal Domain of Drosophila Methoprene-Tolerant Protein.
Q92543673Intrinsic Disorder-Based Emergence in Cellular Biology: Physiological and Pathological Liquid-Liquid Phase Transitions in Cells
Q51574262Intrinsic disorder in S100 proteins.
Q37649609Intrinsic disorder in biomarkers of insulin resistance, hypoadiponectinemia, and endothelial dysfunction among the type 2 diabetic patients
Q30395169Intrinsic disorder in proteins involved in amyotrophic lateral sclerosis
Q30399043Intrinsic disorder in spondins and some of their interacting partners
Q35146628Intrinsic disorder in the BK channel and its interactome
Q59335310Intrinsic disorder in the regulatory N-terminal domain of diacylglycerol acyltransferase 1 from Brassica napus
Q53219534Intrinsic disorder of human Yin Yang 1 protein.
Q98775878Intrinsic disorder perspective of an interplay between the renin-angiotensin-aldosterone system and SARS-CoV-2
Q39172489Intrinsically Disordered Regions in Serum Albumin: What Are They For?
Q27926249Intrinsically Disordered Side of the Zika Virus Proteome
Q28542604Intrinsically disordered and pliable Starmaker-like protein from medaka (Oryzias latipes) controls the formation of calcium carbonate crystals
Q40488052Intrinsically disordered caldesmon binds calmodulin via the "buttons on a string" mechanism
Q30525528Intrinsically disordered proteins aggregate at fungal cell-to-cell channels and regulate intercellular connectivity
Q36604641Intrinsically disordered proteins and conformational noise: implications in cancer
Q38007557Intrinsically disordered proteins and novel strategies for drug discovery
Q42401096Intrinsically disordered proteins and prostate cancer: pouring new wine in an old bottle
Q92697805Intrinsically disordered proteins and structured proteins with intrinsically disordered regions have different functional roles in the cell
Q35135581Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders
Q24633854Intrinsically disordered proteins are potential drug targets
Q57908356Intrinsically disordered proteins as crucial constituents of cellular aqueous two phase systems and coacervates
Q42318119Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif
Q57354509Intrinsically disordered proteins in crowded milieu: when chaos prevails within the cellular gumbo
Q47142042Intrinsically disordered proteins in the nucleus of human cells
Q37528149Intrinsically disordered regions of p53 family are highly diversified in evolution
Q35687046Introgression of the SbASR-1 gene cloned from a halophyte Salicornia brachiate enhances salinity and drought endurance in transgenic groundnut (arachis hypogaea)and acts as a transcription factor [corrected].
Q28070759Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions
Q41682782Is unphosphorylated Rex, as multifunctional protein of HTLV-1, a fully intrinsically disordered protein? An in silico study
Q34473091LPS-annotate: complete annotation of compositionally biased regions in the protein knowledgebase
Q21559553Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations
Q36485075Late embryogenesis abundant proteins protect human hepatoma cells during acute desiccation.
Q38297802Lectins as probes for assessing the accessibility of N-linked glycans in relation to the conformational changes of fibronectin.
Q91817045Life in Phases: Intra- and Inter- Molecular Phase Transitions in Protein Solutions
Q36694319Looking at the carcinogenicity of human insulin analogues via the intrinsic disorder prism
Q40091428M1 RNA is important for the in-cell solubility of its cognate C5 protein: Implications for RNA-mediated protein folding
Q30983595MERA: a webserver for evaluating backbone torsion angle distributions in dynamic and disordered proteins from NMR data
Q30430063Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome
Q30386380Mapping the intrinsically disordered properties of the flexible loop domain of Bcl-2: a molecular dynamics simulation study.
Q34688655Marked variability in the extent of protein disorder within and between viral families
Q38056343Mass spectrometry methods for intrinsically disordered proteins.
Q40222339Maximum-Likelihood Phylogenetic Inference with Selection on Protein Folding Stability
Q37084207Meandering Down the Energy Landscape of Protein Folding: Are We There Yet?
Q42077482Mechanical resistance in unstructured proteins.
Q35342243Mechanical unfolding of cardiac myosin binding protein-C by atomic force microscopy
Q34417638Mechanisms of small-molecule binding to intrinsically disordered proteins
Q34544246Mechanistic insights into mammalian stress granule dynamics.
Q42700418Mhp107 is a member of the multifunctional adhesin family of Mycoplasma hyopneumoniae.
Q33566265Microsecond barrier-limited chain collapse observed by time-resolved FRET and SAXS.
Q34280717MoRFpred, a computational tool for sequence-based prediction and characterization of short disorder-to-order transitioning binding regions in proteins
Q39382681Modeling and molecular dynamics of the intrinsically disordered e7 proteins from high- and low-risk types of human papillomavirus.
Q30401348Modelling the structure of the red cell membrane
Q37311893Modulating the intrinsic disorder in the cytoplasmic domain alters the biological activity of the N-methyl-D-aspartate-sensitive glutamate receptor
Q64087496Modulation of Disordered Proteins with a Focus on Neurodegenerative Diseases and Other Pathologies
Q36615930Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein
Q97539677Molecular and cellular correlates in Kv channel clustering: entropy-based regulation of cluster ion channel density
Q28085091Molecular approaches for improving desiccation tolerance: insights from the brine shrimp Artemia franciscana
Q35562174Molecular crowding enhances facilitated diffusion of two human DNA glycosylases
Q30474096Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating
Q42180912Molecular principles of human virus protein-protein interactions
Q38453820Molecular recognition features (MoRFs) in three domains of life
Q26747089Molecular signaling involving intrinsically disordered proteins in prostate cancer
Q48050089More than just tails: intrinsic disorder in histone proteins
Q37770057Multicolor single-molecule FRET to explore protein folding and binding
Q37218609Multiscaled exploration of coupled folding and binding of an intrinsically disordered molecular recognition element in measles virus nucleoprotein.
Q33737866Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes
Q37919366Mutual effects of disorder and order in fusion proteins between intrinsically disordered domains and fluorescent proteins.
Q91738942Mutually exclusive locales for N-linked glycans and disorder in human glycoproteins
Q28540276NMR characterization of the near native and unfolded states of the PTB domain of Dok1: alternate conformations and residual clusters
Q46854196NMR spectroscopic studies of intrinsically disordered proteins at near-physiological conditions
Q56993044NOT THAT RIGID MIDGETS AND NOT SO FLEXIBLE GIANTS: ON THE ABUNDANCE AND ROLES OF INTRINSIC DISORDER IN SHORT AND LONG PROTEINS
Q27000813NS3 protease from hepatitis C virus: biophysical studies on an intrinsically disordered protein domain
Q40439451Native globular actin has a thermodynamically unstable quasi-stationary structure with elements of intrinsic disorder
Q89849097New technologies to analyse protein function: an intrinsic disorder perspective
Q58062013Nonequilibrium NMR Methods for Monitoring Protein and RNA Folding
Q33747704Nonnative interactions in coupled folding and binding processes of intrinsically disordered proteins
Q89872460Nucleocytoplasmic transport of intrinsically disordered proteins studied by high-speed super-resolution microscopy
Q36163461Nucleocytoplasmic transport: a role for nonspecific competition in karyopherin-nucleoporin interactions
Q52670500On the Regularities of the Polar Profiles of Proteins Related to Ebola Virus Infection and their Functional Domains.
Q41906667On the intrinsic disorder status of the major players in programmed cell death pathways
Q46186165On the potential of using peculiarities of the protein intrinsic disorder distribution in mitochondrial cytochrome b to identify the source of animal meats
Q37615684Open and closed: the roles of linker histones in plants and animals.
Q26739978Order, Disorder, and Everything in Between
Q34981100Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology
Q42367734Overexpression of CsLEA11, a Y3SK2-type dehydrin gene from cucumber (Cucumis sativus), enhances tolerance to heat and cold in Escherichia coli.
Q45222808PELPK1 (At5g09530) contains a unique pentapeptide repeat and is a positive regulator of germination in Arabidopsis thaliana
Q41730413Papillomavirus binding factor (PBF) is an intrinsically disordered protein with potential participation in osteosarcoma genesis, in silico evidence
Q42320836Paradoxes and wonders of intrinsic disorder: Complexity of simplicity
Q91709607Paradoxes and wonders of intrinsic disorder: Stability of instability
Q33909288Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases
Q47661120Phase transition and winding properties of a flexible polymer adsorbed to a rigid perioidic copolymer
Q26739972Phenotypic plasticity in prostate cancer: role of intrinsically disordered proteins
Q42010431Phosphoproteomic analysis reveals major default phosphorylation sites outside long intrinsically disordered regions of Arabidopsis plasma membrane proteins.
Q35888187Phosphorylation Regulates the Bound Structure of an Intrinsically Disordered Protein: The p53-TAZ2 Case.
Q40912194Phosphorylation-coupled intramolecular dynamics of unstructured regions in chromatin remodeler FACT.
Q58114522Physical Background of the Disordered Nature of "Mutual Synergetic Folding" Proteins
Q26823798Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)
Q51596041Picobirnaviruses encode a protein with repeats of the ExxRxNxxxE motif.
Q64075638Plant Extracts and Phytochemicals Targeting -Synuclein Aggregation in Parkinson's Disease Models
Q35874419Plasticity in structural and functional interactions between the phosphoprotein and nucleoprotein of measles virus.
Q38238685PolyQ-mediated regulation of mRNA granules assembly
Q41660989Potential Roles of Intrinsic Disorder in Maternal-Effect Proteins Involved in the Maintenance of DNA Methylation
Q59809159Potential clinical application of lncRNAs in non-small cell lung cancer
Q47710367Potential functions of LEA proteins from the brine shrimp Artemia franciscana - anhydrobiosis meets bioinformatics
Q57789346PreSMo Target-Binding Signatures in Intrinsically Disordered Proteins
Q48104723Prediction of Disordered Regions and Their Roles in the Anti-Pathogenic and Immunomodulatory Functions of Butyrophilins.
Q35051967Prediction of Intrinsic Disorder in MERS-CoV/HCoV-EMC Supports a High Oral-Fecal Transmission
Q39541532Prediction of Protein-Protein Interaction via co-occurring Aligned Pattern Clusters
Q30386377Prediction of intrinsically disordered regions in proteins using signal processing methods: application to heat-shock proteins.
Q97681217Presence of intrinsically disordered proteins can inhibit the nucleation phase of amyloid fibril formation of Aβ(1-42) in amino acid sequence independent manner
Q26801512Protein Folding and Mechanisms of Proteostasis
Q38017957Protein conformational switches: from nature to design
Q36320524Protein folding and the order/disorder paradox
Q34168308Protein folding at the exit tunnel
Q30420136Protein folding: a problem with multiple solutions
Q37541123Protein intrinsic disorder and network connectivity. The case of 14-3-3 proteins
Q37950254Protein intrinsic disorder as a flexible armor and a weapon of HIV-1.
Q36675634Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii
Q28068775Protein stability: a crystallographer's perspective
Q34086494Proteins that switch folds
Q38257180Proteins without unique 3D structures: biotechnological applications of intrinsically unstable/disordered proteins
Q35906430Proteostasis and REDOX state in the heart
Q42073011Protonation-dependent conformational variability of intrinsically disordered proteins.
Q35001178Purification of α-synuclein from human brain reveals an instability of endogenous multimers as the protein approaches purity.
Q37695230Quantification of cellular protein expression and molecular features of group 3 LEA proteins from embryos of Artemia franciscana
Q64951669Raman Sensing and Its Multimodal Combination with Optoacoustics and OCT for Applications in the Life Sciences.
Q54901718Random sequences are an abundant source of bioactive RNAs or peptides.
Q91676754Rational discovery of antimetastatic agents targeting the intrinsically disordered region of MBD2
Q38754422Reactivity of U-associated osteopontin with lactoferrin: a one-to-many complex
Q37986340Reagentless fluorescent biosensors based on proteins for continuous monitoring systems
Q33989616Recognition of the HIV capsid by the TRIM5α restriction factor is mediated by a subset of pre-existing conformations of the TRIM5α SPRY domain
Q37998785Refined views of multi-protein complexes in the erythrocyte membrane
Q37645892Refining Disordered Peptide Ensembles with Computational Amide I Spectroscopy: Application to Elastin-Like Peptides
Q36397739Regulation of the H4 tail binding and folding landscapes via Lys-16 acetylation.
Q38276676Relating gas phase to solution conformations: Lessons from disordered proteins
Q41142944Replica exchange molecular dynamics simulations provide insight into substrate recognition by small heat shock proteins
Q38044416Residual dipolar couplings measured in unfolded proteins are sensitive to amino-acid-specific geometries as well as local conformational sampling
Q30542695Resilience of death: intrinsic disorder in proteins involved in the programmed cell death
Q30372664Rethinking gene regulatory networks in light of alternative splicing, intrinsically disordered protein domains, and post-translational modifications
Q38294224Robust enzyme design: bioinformatic tools for improved protein stability
Q97423280Role of the activation peptide in the mechanism of protein C activation
Q38237445Role of water in protein folding, oligomerization, amyloidosis and miniprotein
Q37057160SARP: A Novel Algorithm to Assess Compositional Biases in Protein Sequences.
Q24620741SPINE-D: accurate prediction of short and long disordered regions by a single neural-network based method
Q30429427Segment assembly, structure alignment and iterative simulation in protein structure prediction
Q48436819Segmental isotope-labeling of the intrinsically disordered protein PQBP1.
Q35372249Senescence-associated barley NAC (NAM, ATAF1,2, CUC) transcription factor interacts with radical-induced cell death 1 through a disordered regulatory domain
Q38688729Sensing Tryptophan Microenvironment of Amyloid Protein Utilizing Wavelength-Selective Fluorescence Approach
Q35842081Sequence TTKF ↓ QE defines the site of proteolytic cleavage in Mhp683 protein, a novel glycosaminoglycan and cilium adhesin of Mycoplasma hyopneumoniae
Q41157592Shell disorder, immune evasion and transmission behaviors among human and animal retroviruses
Q27021549Signal activation and inactivation by the Gα helical domain: a long-neglected partner in G protein signaling
Q35211465Similarities and differences in the structure and function of 4.1G and 4.1R135, two protein 4.1 paralogues expressed in erythroid cells
Q58575706Single Molecule FRET: A Powerful Tool to Study Intrinsically Disordered Proteins
Q35060445Snf2 family gene distribution in higher plant genomes reveals DRD1 expansion and diversification in the tomato genome
Q41954265Soil organic matter and the extracellular microbial matrix show contrasting responses to C and N availability
Q30415112Solvent effect on the folding dynamics and structure of E6-associated protein characterized from ab initio protein folding simulations
Q35656842Splice junctions are constrained by protein disorder
Q64059566Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins
Q51362509Stochastic simulation of structural properties of natively unfolded and denatured proteins.
Q38779711Strain phenomenon in protein aggregation: Interplay between sequence and conformation
Q39661785Structural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures.
Q35078181Structural and dynamical insights into the membrane-bound α-synuclein
Q44084623Structural and functional characterization of the MERIT40 to understand its role in DNA repair
Q40070144Structural and mechanistic insights into nuclear transport and delivery of the critical pluripotency factor Oct4 to DNA.
Q57071963Structural biology: Breaking the protein rules
Q41864504Structural characterization of an intrinsically unfolded mini-HBX protein from hepatitis B virus
Q35119328Structural characterization of two alternate conformations in a calbindin D₉k-based molecular switch
Q38130678Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease.
Q34230264Structural disorder in eukaryotes
Q59350859Structural disorder in the proteome and interactome of Alkhurma virus (ALKV)
Q35333283Structural disorder of folded proteins: isotope-edited 2D IR spectroscopy and Markov state modeling
Q38136613Structural features and interfacial properties of WH2, β-thymosin domains and other intrinsically disordered domains in the regulation of actin cytoskeleton dynamics.
Q39582237Structural features within the nascent chain regulate alternative targeting of secretory proteins to mitochondria
Q34276839Structural genomics plucks high-hanging membrane proteins
Q30402034Structural gymnastics of multifunctional metamorphic proteins.
Q64059747Structural properties and enzyme stabilization function of the intrinsically disordered LEA_4 protein TdLEA3 from wheat
Q34720695Structure and non-structure of centrosomal proteins.
Q34268576Structure and size determination of bacteriophage P2 and P4 procapsids: function of size responsiveness mutations
Q38005681Structure of metabotropic glutamate receptor C-terminal domains in contact with interacting proteins
Q37173275Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system
Q41698527Structured States of Disordered Proteins from Genomic Sequences
Q30786211Synergistic Biomineralization Phenomena Created by a Combinatorial Nacre Protein Model System
Q36020398Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D(2) concept
Q35835558Targeting intrinsically disordered proteins in rational drug discovery
Q28539839Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease
Q89900634Taurine Induces an Ordered but Functionally Inactive Conformation in Intrinsically Disordered Casein Proteins
Q34510555The Arabidopsis thaliana SERK1 kinase domain spontaneously refolds to an active state in vitro
Q57814568The BackMAP Python module: how a simpler Ramachandran number can simplify the life of a protein simulator
Q26782895The Cellular Prion Protein: A Player in Immunological Quiescence
Q36444189The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub.
Q54380629The Dad1 subunit of the yeast kinetochore Dam1 complex is an intrinsically disordered protein
Q64759679The Gut and Parkinson's Disease-A Bidirectional Pathway.
Q91802216The Isolation of New Pore-Forming Toxins from the Sea Anemone Actinia fragacea Provides Insights into the Mechanisms of Actinoporin Evolution
Q40434276The Proline/Glycine-Rich Region of the Biofilm Adhesion Protein Aap Forms an Extended Stalk that Resists Compaction.
Q53090758The STIL protein contains intrinsically disordered regions that mediate its protein-protein interactions.
Q34283949The SbASR-1 gene cloned from an extreme halophyte Salicornia brachiata enhances salt tolerance in transgenic tobacco
Q47586836The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins
Q38779767The alphabet of intrinsic disorder: I. Act like a Pro: On the abundance and roles of proline residues in intrinsically disordered proteins
Q30402098The alphabet of intrinsic disorder: II. Various roles of glutamic acid in ordered and intrinsically disordered proteins
Q34421102The amyloid state and its association with protein misfolding diseases.
Q39957451The challenge of increasing Pfam coverage of the human proteome
Q24298721The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity
Q28080017The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease
Q35656560The dark sides of capillary morphogenesis gene 2.
Q34161178The fractal globule as a model of chromatin architecture in the cell
Q30399038The intrinsic disorder alphabet. III. Dual personality of serine
Q42223133The intrinsic disorder status of the human hepatitis C virus proteome
Q50914408The intrinsically disordered C-terminal region of Arabidopsis thaliana TCP8 transcription factor acts both as a transactivation and self-assembly domain.
Q41462823The intrinsically disordered N-terminal region of AtREM1.3 remorin protein mediates protein-protein interactions
Q41826587The intrinsically disordered nuclear localization signal and phosphorylation segments distinguish the membrane affinity of two cytidylyltransferase isoforms
Q36205942The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments
Q42209317The lysine-rich motif of intrinsically disordered stress protein CDeT11-24 from Craterostigma plantagineum is responsible for phosphatidic acid binding and protection of enzymes from damaging effects caused by desiccation
Q42199690The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb
Q38105815The most important thing is the tail: multitudinous functionalities of intrinsically disordered protein termini
Q38527462The multifaceted roles of intrinsic disorder in protein complexes
Q39155657The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1.
Q36019033The role of protein intrinsic disorder in major psychiatric disorders
Q47693846The roles of intrinsic disorder-based liquid-liquid phase transitions in the "Dr. Jekyll-Mr. Hyde" behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
Q85991514The secretion of an intrinsically disordered protein with different secretion signals in Bacillus subtilis
Q42663688The structural and functional signatures of proteins that undergo multiple events of post-translational modification
Q42021486The transiently ordered regions in intrinsically disordered ExsE are correlated with structural elements involved in chaperone binding.
Q38845618The yeast Hsp70 homolog Ssb: a chaperone for general de novo protein folding and a nanny for specific intrinsically disordered protein domains
Q39175147The α-helical structure of prodomains promotes translocation of intrinsically disordered neuropeptide hormones into the endoplasmic reticulum
Q38806231Therapeutic Interventions of Cancers Using Intrinsically Disordered Proteins as Drug Targets: c-Myc as Model System.
Q57329080Thermodynamics of Conformational Transitions in a Disordered Protein Backbone Model
Q36835557Tick receptor for outer surface protein A from Ixodes ricinus - the first intrinsically disordered protein involved in vector-microbe recognition
Q59801813Transient Secondary Structures as General Target-Binding Motifs in Intrinsically Disordered Proteins
Q36384806Transient β-hairpin formation in α-synuclein monomer revealed by coarse-grained molecular dynamics simulation
Q54582677Tunable membrane binding of the intrinsically disordered dehydrin Lti30, a cold-induced plant stress protein.
Q51060526Tuning the precision of predictors to reduce overestimation of protein disorder over large datasets.
Q36218535Two Isoforms of Yersinia pestis Plasminogen Activator Pla: Intraspecies Distribution, Intrinsic Disorder Propensity, and Contribution to Virulence
Q27688964Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations
Q28538256Tyrosine phosphorylation within the intrinsically disordered cytosolic domains of the B-cell receptor: an NMR-based structural analysis
Q92819462ULK1/2 Restricts the Formation of Inducible SINT-Speckles, Membraneless Organelles Controlling the Threshold of TBK1 Activation
Q50919522Under-folded proteins: Conformational ensembles and their roles in protein folding, function, and pathogenesis.
Q36336728Understanding Viral Transmission Behavior via Protein Intrinsic Disorder Prediction: Coronaviruses
Q49759325Understanding the roles of intrinsic disorder in subunits of hemoglobin and the disease process of sickle cell anemia.
Q51019237Unified description of solvent effects in the helix-coil transition.
Q38288126Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids
Q37649607Unreported intrinsic disorder in proteins: Building connections to the literature on IDPs
Q30375946Unstructural biology of the Dengue virus proteins.
Q37592050Variation of free-energy landscape of the p53 C-terminal domain induced by acetylation: Enhanced conformational sampling
Q35064280Visualization of the nanospring dynamics of the IkappaBalpha ankyrin repeat domain in real time
Q27012942What macromolecular crowding can do to a protein
Q33656573What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered
Q27000495Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators
Q36126137Yersinia pestis Caf1 Protein: Effect of Sequence Polymorphism on Intrinsic Disorder Propensity, Serological Cross-Reactivity and Cross-Protectivity of Isoforms
Q54989440Young Genes are Highly Disordered as Predicted by the Preadaptation Hypothesis of De Novo Gene Birth.
Q42748029mRNA imprinting: Additional level in the regulation of gene expression
Q28079390p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum Concept
Q30546746pH-triggered conformational switching of the diphtheria toxin T-domain: the roles of N-terminal histidines

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