Natural Product Target Network Reveals Potential for Cancer Combination Therapies

scientific article published on 31 May 2019

Natural Product Target Network Reveals Potential for Cancer Combination Therapies is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FPHAR.2019.00557
P932PMC publication ID6555193
P698PubMed publication ID31214023

P50authorAurora S BlucherQ89111566
P2093author name stringGuanming Wu
Shannon McWeeney
Molly Kulesz-Martin
Lynne Shinto
Gabrielle Choonoo
Steven R Chamberlin
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
KEGG: kyoto encyclopedia of genes and genomesQ24515297
DrugBank 4.0: shedding new light on drug metabolismQ24568341
A Comparative Analysis of Community Detection Algorithms on Artificial NetworksQ26779592
The Chemical Translation Service--a web-based tool to improve standardization of metabolomic reportsQ27062596
A comparative study of cancer proteins in the human protein-protein interaction networkQ27496590
The BioGRID interaction database: 2015 updateQ28252221
Network pharmacology: the next paradigm in drug discoveryQ28297997
Use of natural products as chemical library for drug discovery and network pharmacologyQ28487019
AfroDb: a select highly potent and diverse natural product library from African medicinal plantsQ28534724
Synergistic and antagonistic drug combinations depend on network topologyQ28542101
TarNet: An Evidence-Based Database for Natural Medicine ResearchQ28552085
BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacologyQ28603124
Drug-target networkQ29614447
Global mapping of pharmacological spaceQ29615876
Cancer drug resistance: an evolving paradigmQ29616694
A human functional protein interaction network and its application to cancer data analysisQ33581341
Network systems biology for drug discoveryQ33592795
The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expressionQ33695077
Network target for screening synergistic drug combinations with application to traditional Chinese medicineQ33937467
Mining the metabiome: identifying novel natural products from microbial communitiesQ34228002
Combinatorial drug therapy for cancer in the post-genomic era.Q34287101
Drug resistance in cancer: an overview.Q34437369
The re-emergence of natural products for drug discovery in the genomics era.Q34459318
Topology of molecular interaction networksQ34508185
Natural Products as Sources of New Drugs from 1981 to 2014.Q34512692
Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations.Q52806460
Quantification of Pathway Cross-talk Reveals Novel Synergistic Drug Combinations for Breast Cancer.Q53760450
Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogsQ59799448
Regulatory network motifs and hotspots of cancer genes in a mammalian cellular signalling networkQ81378507
Mechanisms of drug combinations: interaction and network perspectivesQ83265745
Rocaglamide enhances NK cell-mediated killing of non-small cell lung cancer cells by inhibiting autophagyQ89406920
Phorbol esters: structure, biological activity, and toxicity in animals.Q34657244
Using graph theory to analyze biological networksQ35005792
Do cancer proteins really interact strongly in the human protein-protein interaction network?Q35034277
The Reactome pathway KnowledgebaseQ35866115
The human phosphotyrosine signaling network: evolution and hotspots of hijacking in cancerQ36093876
Combining genomic and network characteristics for extended capability in predicting synergistic drugs for cancer.Q36139333
A map of human cancer signalingQ36327214
A Network-Based Model of Oncogenic Collaboration for Prediction of Drug Sensitivity.Q36396515
TCMID: Traditional Chinese Medicine integrative database for herb molecular mechanism analysisQ36491360
Getting connected: analysis and principles of biological networksQ36808436
Therapeutic target database update 2014: a resource for targeted therapeuticsQ37661746
Exploring compound promiscuity patterns and multi-target activity spacesQ38201052
Rocaglamide breaks TRAIL-resistance in human multiple myeloma and acute T-cell leukemia in vivo in a mouse xenogtraft modelQ38725199
Combinatorial resveratrol and quercetin polymeric micelles mitigate doxorubicin induced cardiotoxicity in vitro and in vivo.Q38854749
Phytomedicine-Modulating oxidative stress and the tumor microenvironment for cancer therapyQ38994318
Predicting synergistic effects between compounds through their structural similarity and effects on transcriptomesQ39474699
Patient compliance with cervical smear surveillance in a shared-care setting.Q39566432
Evidence-Based and Quantitative Prioritization of Tool Compounds in Phenotypic Drug DiscoveryQ39592577
Perspectives on the development of imatinib and the future of cancer researchQ39940683
Synergy evaluation by a pathway-pathway interaction network: a new way to predict drug combinationQ40188819
DrugComboRanker: drug combination discovery based on target network analysisQ40749664
Construction of human activity-based phosphorylation networks.Q40836487
Utility of network integrity methods in therapeutic target identificationQ41829537
High-resolution view of compound promiscuityQ42090248
Identification of information flow-modulating drug targets: a novel bridging paradigm for drug discoveryQ46260661
Overcoming resistance to cetuximab with honokiol, a small-molecule polyphenolQ46278768
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY.Q47139831
Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or SynergyQ47303076
Evidence-Based Precision Oncology with the Cancer Targetome.Q47893147
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
P921main subjectnatural productQ901227
P304page(s)557
P577publication date2019-05-31
P1433published inFrontiers in PharmacologyQ2681208
P1476titleNatural Product Target Network Reveals Potential for Cancer Combination Therapies
P478volume10

Reverse relations

cites work (P2860)
Q898347792α-Hydroxyeudesma-4,11(13)-Dien-8β,12-Olide Isolated from Inula britannica Induces Apoptosis in Diffuse Large B-cell Lymphoma Cells
Q92630031Chelerythrine Chloride Downregulates β-Catenin and Inhibits Stem Cell Properties of Non-Small Cell Lung Carcinoma
Q92153398Multifloroside Suppressing Proliferation and Colony Formation, Inducing S Cell Cycle Arrest, ROS Production, and Increasing MMP in Human Epidermoid Carcinoma Cell Lines A431

Search more.