Therapeutic Effect of pHLIP-mediated CEACAM6 Gene Silencing in Lung Adenocarcinoma

scientific article published on 02 September 2019

Therapeutic Effect of pHLIP-mediated CEACAM6 Gene Silencing in Lung Adenocarcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-019-48104-5
P932PMC publication ID6717735
P698PubMed publication ID31474761

P2093author name stringSung-Hoon Lee
Ok-Jun Lee
Chang Gok Woo
Jieun Yun
Hyung Geun Song
Ho-Chang Lee
Hyun-Jun Lee
Seung-Myoung Son
Hye Sook Han
Young-Mi Gu
Young Hyun Lim
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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cellsQ27860926
MicroRNA-29a suppresses the growth, migration, and invasion of lung adenocarcinoma cells by targeting carcinoembryonic antigen-related cell adhesion molecule 6Q28116258
Extracellular N-domain alone can mediate specific heterophilic adhesion between members of the carcinoembryonic antigen family, CEACAM6 and CEACAM8Q28138736
CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cellsQ28238822
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Sequence and glycosylation site identity of two distinct glycoforms of nonspecific cross-reacting antigen as demonstrated by sequence analysis and fast atom bombardment mass spectrometryQ28285587
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Deregulation of the CEACAM expression pattern causes undifferentiated cell growth in human lung adenocarcinoma cellsQ33525547
Therapeutic effect of anti CEACAM6 monoclonal antibody against lung adenocarcinoma by enhancing anoikis sensitivityQ34044546
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Translocation of molecules into cells by pH-dependent insertion of a transmembrane helixQ34536701
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Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinomaQ36385644
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pH (low) insertion peptide (pHLIP) targets ischemic myocardiumQ36512156
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Design and activity of a murine and humanized anti-CEACAM6 single-chain variable fragment in the treatment of pancreatic cancer.Q37168610
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Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cellsQ37422870
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A549 cells adapted to high nitric oxide show reduced surface CEACAM expression and altered adhesion and migration propertiesQ38929320
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CEACAM6 gene expression in intrahepatic cholangiocarcinomaQ40251499
Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen).Q40365821
Peptide nucleic acid (PNA). A DNA mimic with a peptide backboneQ40760039
Dual role of carcinoembryonic antigen-related cell adhesion molecule 6 expression in predicting the overall survival of gastric cancer patientsQ41534014
Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice.Q43763050
Expression of CEACAM6 in Resectable Colorectal Cancer: A Factor of Independent Prognostic SignificanceQ44598294
Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6.Q46019803
Redefined nomenclature for members of the carcinoembryonic antigen familyQ48738225
Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma.Q51743199
Breast carcinoma with amplified HER2: a gene expression signature specific for trastuzumab resistance and poor prognosis.Q53463534
Systemic siRNA-mediated gene silencing: a new approach to targeted therapy of cancer.Q54700470
Antibody By114 is selective for the 90 kD PI-linked component of the CD66 antigen: a new reagent for the study of paroxysmal nocturnal haemoglobinuriaQ70565673
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CEACAM6 is a novel biomarker in pancreatic adenocarcinoma and PanIN lesionsQ81436009
P433issue1
P921main subjectgene silencingQ1431332
P304page(s)11607
P577publication date2019-09-02
P1433published inScientific ReportsQ2261792
P1476titleTherapeutic Effect of pHLIP-mediated CEACAM6 Gene Silencing in Lung Adenocarcinoma
P478volume9

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cites work (P2860)
Q97438364In vivo gene delivery mediated by non-viral vectors for cancer therapy
Q95267829The Synchronous Presence of Multiple Myelomas and Other Primary Malignant Tumors: Case Series with Literature Review

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