Target-Derived Neurotrophic Factor Deprivation Puts Retinal Ganglion Cells on Death Row: Cold Hard Evidence and Caveats

scientific article published on 03 September 2019

Target-Derived Neurotrophic Factor Deprivation Puts Retinal Ganglion Cells on Death Row: Cold Hard Evidence and Caveats is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3390/IJMS20174314
P953full work available at URLhttps://www.mdpi.com/1422-0067/20/17/4314
P932PMC publication ID6747494
P698PubMed publication ID31484425

P50authorLieve MoonsQ50923690
Lies De GroefQ38546825
P2093author name stringLies De Groef
Lieve Moons
Marie Claes
P2860cites workRegional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brainQ24556530
No evidence of association of heterozygous NTF4 mutations in patients with primary open-angle glaucomaQ24632719
Neurotrophins: roles in neuronal development and functionQ24656166
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucomaQ24657994
The intricacies of neurotrophic factor therapy for retinal ganglion cell rescue in glaucoma: a case for gene therapyQ26740095
Trk receptors: roles in neuronal signal transductionQ27919636
Neuroprotection, Growth Factors and BDNF-TrkB Signalling in Retinal DegenerationQ28069477
Selectivity in neurotrophin signaling: theme and variationsQ28211196
Variations in NTF4, VAV2, and VAV3 genes are not involved with primary open-angle and primary angle-closure glaucomas in an indian populationQ28282235
Müller Cells as a source of brain-derived neurotrophic factor in the retina: noradrenaline upregulates brain-derived neurotrophic factor levels in cultured rat Müller cellsQ28565607
Neuroprotective effect of transcorneal electrical stimulation on light-induced photoreceptor degenerationQ28567163
Anti-semaphorin 3A antibodies rescue retinal ganglion cells from cell death following optic nerve axotomyQ28567462
Interaction between two glaucoma genes, optineurin and myocilinQ28573610
Effect of electrical stimulation on IGF-1 transcription by L-type calcium channels in cultured retinal Müller cellsQ28577972
Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophinsQ28581113
Chronic and Acute Models of Retinal Neurodegeneration TrkA Activity Are Neuroprotective whereas p75NTR Activity Is Neurotoxic through a Paracrine MechanismQ28584166
Brain-Derived Neurotrophic Factor as a Biomarker in Primary Open-Angle GlaucomaQ28584300
Neurotrophins and their receptors: a convergence point for many signalling pathwaysQ29616108
Brain-derived neurotrophic factor reduces TrkB protein and mRNA in the normal retina and following optic nerve crush in adult ratsQ33202883
Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetricQ33259237
Effect of CNTF on retinal ganglion cell survival in experimental glaucomaQ33390314
Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degenerationQ33511068
Genetic control of programmed cell death during animal developmentQ33589613
Sight and insight--on the physiological role of nitric oxide in the visual systemQ33591939
p75NTR: A study in contrastsQ33592257
Intrinsic survival mechanisms for retinal ganglion cells.Q33609311
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism.Q33640028
Effect of transcorneal electrical stimulation in patients with nonarteritic ischemic optic neuropathy or traumatic optic neuropathy.Q51182839
Glaucoma pathogenesis and neurotrophins: Focus on the Molecular and Genetic basis for Therapeutic prospects.Q52314492
Regeneration-associated genes on optic nerve regeneration in fish retina.Q53060814
The return of phosphorylated and nonphosphorylated epitopes of neurofilament proteins to the regenerating optic nerve of Xenopus laevis.Q53842587
Design of a Novel Gene Therapy Construct to Achieve Sustained Brain-Derived Neurotrophic Factor Signaling in Neurons.Q54125189
Expression of brain-derived neurotrophic factor and of its functional receptor in neonatal and adult rat retina.Q54769290
Progress in Gene Therapy to Prevent Retinal Ganglion Cell Loss in Glaucoma and Leber's Hereditary Optic Neuropathy.Q55039934
The Role of Endogenous Neuroprotective Mechanisms in the Prevention of Retinal Ganglion Cells DegenerationQ59800987
In vivo effects of single or combined topical neuroprotective and regenerative agents on degeneration of retinal ganglion cells in rat optic nerve crush modelQ60909978
Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypesQ61136494
An Antagonistic Axon-Dendrite Interplay Enables Efficient Neuronal Repair in the Adult Zebrafish Central Nervous SystemQ61641940
Axotomy-induced retinal ganglion cell death in adult mice: Quantitative and topographic time course analysesQ63437442
Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and InjuryQ64085292
Cell death in the retinal ganglion cell layer during optic nerve regeneration for the frog Rana pipiensQ68802846
Long-term in vivo inhibition of CNS neurodegeneration by Bcl-XL gene transferQ45280303
Transcorneal alternating current stimulation after severe axon damage in rats results in "long-term silent survivor" neurons.Q45737288
AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cellsQ45858441
Transduction of axotomized retinal ganglion cells by adenoviral vector administration at the optic nerve stump: an in vivo model system for the inhibition of neuronal apoptotic cell death.Q45862828
Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucomaQ45884480
Nitric oxide-cGMP signaling regulates axonal elongation during optic nerve regeneration in the goldfish in vitro and in vivo.Q46003854
Effect of brain-derived neurotrophic factor on mouse axotomized retinal ganglion cells and phagocytic microgliaQ46097407
BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity.Q46403699
Transcorneal electrical stimulation rescues axotomized retinal ganglion cells by activating endogenous retinal IGF-1 systemQ46508379
Direct effect of electrical stimulation on induction of brain-derived neurotrophic factor from cultured retinal Müller cellsQ46551168
Degenerative alterations in the visual pathway after NMDA-induced retinal damage in miceQ46623795
Inhibition and recovery of retrograde axoplasmic transport in rat optic nerve during and after elevated IOP in vivoQ46655285
Clathrin-dependent endocytosis is required for TrkB-dependent Akt-mediated neuronal protection and dendritic growth.Q46691984
Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucomaQ46704887
Neurotrophic factor synergy is required for neuronal survival and disinhibited axon regeneration after CNS injuryQ46844217
Expression of ciliary neurotrophic factor after induction of ocular hypertension in the retina of rats.Q46889405
Prolonged administration of NT-4/5 fails to rescue most axotomized retinal ganglion cells in adult ratsQ47833136
Complementary research models and methods to study axonal regeneration in the vertebrate retinofugal systemQ47942893
Brain-Derived Neurotrophic Factor in Patients with Primary Open-Angle Glaucoma and Age-related CataractQ47977962
Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo.Q48009496
Neurotrophin-7: a novel member of the neurotrophin family from the zebrafishQ48038263
Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats.Q48093574
Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling.Q48142730
Characterization of retinal ganglion cell, horizontal cell, and amacrine cell types expressing the neurotrophic receptor tyrosine kinase Ret.Q48155035
Neurotrophins and their receptors in the tench retina during optic nerve regenerationQ48287267
Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: effects of kainate lesions in the superior colliculusQ48300508
Atrophy and degeneration of ganglion cells in central retina following loss of postsynaptic target neurons in the dorsal lateral geniculate nucleus of the adult cat.Q48360577
Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult ratsQ48364946
Electrical stimulation ameliorates light-induced photoreceptor degeneration in vitro via suppressing the proinflammatory effect of microglia and enhancing the neurotrophic potential of Müller cellsQ48378791
Brain-derived neurotrophic factor in patients with normal-tension glaucomaQ48423050
Loss and displacement of ganglion cells after optic nerve regeneration in adult Rana pipiensQ48446045
The effects of central administration of neurotrophins or transplants of fetal tectal tissue on retinal ganglion cell survival following removal of the superior colliculus in neonatal ratsQ48462164
Contributions of the optic tectum and the retina as sources of brain-derived neurotrophic factor for retinal ganglion cells in the chick embryo.Q48487216
Noninvasive transorbital alternating current stimulation improves subjective visual functioning and vision-related quality of life in optic neuropathyQ48574188
A qualitative comparison of the reactions of retinal ganglion cell axons to optic nerve crush in neonatal and adult mice.Q48606124
Restoration of vision after optic nerve lesions with noninvasive transorbital alternating current stimulation: a clinical observational studyQ48856818
A sensitive period for ganglion cell degeneration and the formation of aberrant retino-fugal connections following tectal lesions in ratsQ48972865
Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo studyQ49108408
Distal axonopathy with structural persistence in glaucomatous neurodegenerationQ33740029
Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neuronsQ33792600
Combined application of BDNF to the eye and brain enhances ganglion cell survival and function in the cat after optic nerve injuryQ33847477
Restoration of the retinofugal pathwayQ33990152
Gene expression profiling of the retina after transcorneal electrical stimulation in wild-type Brown Norway ratsQ34004605
Nitric oxide down-regulates brain-derived neurotrophic factor secretion in cultured hippocampal neuronsQ34017513
Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fishQ34039544
Live or let die - retinal ganglion cell death and survival during development and in the lesioned adult CNS.Q34046206
Time Course Analysis of Gene Expression Patterns in Zebrafish Eye During Optic Nerve RegenerationQ34080374
Neurotrophins use the Erk5 pathway to mediate a retrograde survival response.Q34090264
Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approachesQ34156542
Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucomaQ34198719
Long-distance retrograde neurotrophic factor signalling in neuronsQ34328577
The yin and yang of neurotrophin actionQ34439423
The definition and classification of glaucoma in prevalence surveysQ34508710
Neurogenesis of retinal ganglion cells is not essential to visual functional recovery after optic nerve injury in adult zebrafishQ34600351
Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degenerationQ34794630
BDNF and HSP gene polymorphisms and their influence on the progression of primary open-angle glaucoma in a Polish populationQ34974309
A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucomaQ35082369
Analysis of the expression and polymorphism of APOE, HSP, BDNF, and GRIN2B genes associated with the neurodegeneration process in the pathogenesis of primary open angle glaucomaQ35373186
Expression of inducible heat shock proteins Hsp27 and Hsp70 in the visual pathway of rats subjected to various models of retinal ganglion cell injuryQ35533015
Effects of ocular hypertension in the visual system of pigmented miceQ35587405
Axonal regeneration of fish optic nerve after injuryQ35729700
Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkBQ35839275
Differential visual system organization and susceptibility to experimental models of optic neuropathies in three commonly used mouse strainsQ35899338
Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cellsQ36014895
Alternating Current Stimulation for Vision Restoration after Optic Nerve Damage: A Randomized Clinical TrialQ36063961
Therapeutic potential of neurotrophic factors in neurodegenerative diseasesQ36088169
Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System after Optic Nerve InjuryQ36127906
Glaucoma: thinking in new ways-a rôle for autonomous axonal self-destruction and other compartmentalised processes?Q36161727
Functions and mechanisms of retrograde neurotrophin signallingQ36215528
Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central targetQ36501562
Apoptosis regulates ipRGC spacing necessary for rods and cones to drive circadian photoentrainment.Q36602415
Retrograde signaling in the optic nerve is necessary for electrical responsiveness of retinal ganglion cellsQ36617805
Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse modelQ38747586
Optic nerve transection: a model of adult neuron apoptosis in the central nervous systemQ38758998
Using Electrical Stimulation to Enhance the Efficacy of Cell Transplantation Therapies for Neurodegenerative Retinal Diseases: Concepts, Challenges, and Future PerspectivesQ38762321
Exploring Optic Nerve Axon RegenerationQ38777316
Electrical Stimulation as a Means for Improving VisionQ38803756
Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 1: Where have we been and what have we learned?Q38804087
A Possible Role of Neuroglobin in the Retina After Optic Nerve Injury: A Comparative Study of Zebrafish and Mouse Retina.Q38831015
Retrograde transport of neurotrophic factor signaling: implications in neuronal development and pathogenesisQ38869277
Regenerating reptile retinas: a comparative approach to restoring retinal ganglion cell functionQ39005377
Functional characterization of fish neuroglobin: zebrafish neuroglobin is highly expressed in amacrine cells after optic nerve injury and can translocate into ZF4 cells.Q39182175
Protective effects of 7,8-dihydroxyflavone on retinal ganglion and RGC-5 cells against excitotoxic and oxidative stress.Q39262019
Retinal expression of Fgf2 in RCS rats with subretinal microphotodiode arrayQ39352997
Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkeyQ39432089
Regeneration of the frog optic nerve. Comparisons with developmentQ39667245
An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucomaQ39720313
Comparison of expression profile of neurotrophins and their receptors in primary and transformed rat retinal ganglion cells.Q40097792
Optic nerve dynein motor protein distribution changes with intraocular pressure elevation in a rat model of glaucomaQ40341960
Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration.Q40692091
Neurturin enhances the survival of axotomized retinal ganglion cells in vivo: combined effects with glial cell line-derived neurotrophic factor and brain-derived neurotrophic factorQ40743424
Glial cell line-derived neurotrophic factor (GDNF) promotes the survival of axotomized retinal ganglion cells in adult rats: comparison to and combination with brain-derived neurotrophic factor (BDNF).Q40972568
Descending optic nerve degeneration in primatesQ41294852
Glaucoma: Biological Trabecular and Neuroretinal Pathology with Perspectives of Therapy Innovation and Preventive DiagnosisQ41455152
Analysis of the astray/robo2 zebrafish mutant reveals that degenerating tracts do not provide strong guidance cues for regenerating optic axons.Q42102114
Differential effects of BDNF and neurotrophin 4 (NT4) on endocytic sorting of TrkB receptorsQ42402737
Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridizationQ42485398
Cloning, mapping, and retinal expression of the canine ciliary neurotrophic factor receptor alpha (CNTFRalpha).Q42604422
Does elevated intraocular pressure reduce retinal TRKB-mediated survival signaling in experimental glaucoma?Q42671324
Dynamic imaging of axonal transport in living retinal ganglion cells in vitroQ42751399
Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J miceQ42914157
Involvement of brain-derived neurotrophic factor in time-dependent neurodegeneration in the murine superior colliculus after intravitreal injection of N-methyl-D-aspartate.Q42968438
BDNF-induced nitric oxide signals in cultured rat hippocampal neurons: time course, mechanism of generation, and effect on neurotrophin secretionQ42986150
Sema-3A indirectly disrupts the regeneration process of goldfish optic nerve after controlled injuryQ43070415
Survival of retinal ganglion cells after transection of the optic nerve in adult cats: a quantitative study within two weeksQ43603877
Neurotrophin and neurotrophin receptor expression by cells of the human lamina cribrosaQ43723400
Rat retinal ganglion cells co-express brain derived neurotrophic factor (BDNF) and its receptor TrkB.Q43865355
Extent of retinal ganglion cell death in the frog Litoria moorei after optic nerve regeneration induced by lesions of different sizesQ43947350
TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo.Q43999162
Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma modelQ44003999
Time-course and extent of retinal ganglion cell death following ablation of the superior colliculus in neonatal ratsQ44053166
Local and target-derived brain-derived neurotrophic factor exert opposing effects on the dendritic arborization of retinal ganglion cells in vivo.Q44115062
Immunohistochemical localization of CNTFRalpha in adult mouse retina and optic nerve following intraorbital nerve crush: evidence for the axonal loss of a trophic factor receptor after injuryQ44243398
FGF-2 modulates expression and distribution of GAP-43 in frog retinal ganglion cells after optic nerve injuryQ44536787
Axonal sprouting in the optic nerve is not a prerequisite for successful regeneration.Q44579693
In vivo expression of neurotrophins and neurotrophin receptors is conserved in adult porcine retina in vitroQ44595306
Rabbit retinal ganglion cell survival after optic nerve section and its effect on the inner plexiform layerQ44687936
Ganglion cell death in rat retina by persistent intraocular pressure elevationQ44979472
Retinal ganglion cell death during optic nerve regeneration in the frog Hyla mooreiQ68945497
Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerveQ70023645
Intracranial transection of the optic nerve in adult mice: preliminary observationsQ70399404
Viability of retinal ganglion cells after optic nerve crush in adult ratsQ70622721
Avian retinal ganglion cells resistant to degeneration after optic nerve lesionQ71158028
BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neuronsQ71383353
Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosisQ72131673
Changes in the morphology and amino acid incorporation of regenerating goldfish optic neuronsQ72384440
Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transportQ72604001
Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damageQ72633267
Rapid axonal transport in primate optic nerve. Distribution of pressure-induced interruptionQ72633272
Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in ratsQ73006494
Chronology of optic nerve head and retinal responses to elevated intraocular pressureQ73437263
Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucomaQ73535458
NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signalsQ73631398
Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the ratQ73666347
Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3'-kinase/protein kinase B signalingQ74339196
NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathwayQ77334867
Nitric oxide synthase inhibition delays axonal degeneration and promotes the survival of axotomized retinal ganglion cellsQ78025681
Early downregulation of IGF-I decides the fate of rat retinal ganglion cells after optic nerve injuryQ79960329
Upregulation of IGF-I in the goldfish retinal ganglion cells during the early stage of optic nerve regenerationQ79960331
Repetitive transorbital alternating current stimulation in optic neuropathyQ82899302
Effects of steroid administration and transcorneal electrical stimulation on the anatomic and electrophysiologic deterioration of nonarteritic ischemic optic neuropathy in a rodent modelQ86748064
Retrograde neurotrophic signaling in rat retinal ganglion cells is transmitted via the ERK5 but not the ERK1/2 pathwayQ87048196
Mechanisms of neurotrophin trafficking via Trk receptorsQ88215951
Brain-Derived Neurotrophic Factor in Patients With Age-Related Macular Degeneration and Its Correlation With Retinal Layer ThicknessesQ90342461
Optogenetic Stimulation of the Superior Colliculus Confers Retinal Neuroprotection in a Mouse Glaucoma ModelQ91098773
Pronounced synergistic neuroprotective effect of GDNF and CNTF on axotomized retinal ganglion cells in the adult mouseQ91595058
Neuroprotective therapies in glaucoma: I. Neurotrophic factor deliveryQ38573732
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucomaQ36639100
Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crushQ36717830
Optic nerve hydropic axonal degeneration and blocked retrograde axoplasmic transport: histopathologic features in human high-pressure secondary glaucomaQ36758035
A new mouse model of inducible, chronic retinal ganglion cell dysfunction not associated with cell deathQ36766606
From ocular hypertension to ganglion cell death: a theoretical sequence of events leading to glaucomaQ36773528
Microglia activation in retinal degenerationQ36779168
Message in a bottle: long-range retrograde signaling in the nervous systemQ37009283
The neurobiology of cell death in glaucomaQ37044571
Shared and distinct retinal input to the mouse superior colliculus and dorsal lateral geniculate nucleusQ37171229
Action in the axon: generation and transport of signaling endosomesQ37263494
Neurotrophin roles in retinal ganglion cell survival: lessons from rat glaucoma modelsQ37393418
Electrical activity enhances neuronal survival and regeneration.Q37590054
Neuronal signaling through endocytosisQ37615176
The cell and molecular biology of glaucoma: mechanisms of retinal ganglion cell deathQ37708805
Diverse Central Projection Patterns of Retinal Ganglion CellsQ37710050
Cell death during development of the nervous systemQ37716922
The expanding universe of neurotrophic factors: therapeutic potential in aging and age-associated disorders.Q37730145
Mechanisms of retinal ganglion cell injury and defense in glaucomaQ37731595
Neurotrophic factor delivery as a protective treatment for glaucomaQ37777778
The molecular basis of retinal ganglion cell death in glaucomaQ37966513
The neurotrophin family of neurotrophic factors: an overviewQ37988419
Neurotrophin signaling via long-distance axonal transportQ37992149
Axonal transport deficits and neurodegenerative diseasesQ38077679
A molecular mechanism of optic nerve regeneration in fish: the retinoid signaling pathway.Q38133166
Neurotrophins: transcription and translationQ38199410
Neurotrophins in the regulation of cellular survival and deathQ38199413
The neurotrophic theory and naturally occurring motoneuron deathQ38206666
Glial cell interactions and glaucomaQ38285754
Heterogeneous nuclear ribonucleoprotein K, an RNA-binding protein, is required for optic axon regeneration in Xenopus laevis.Q38327065
Programmed cell death in neurodevelopmentQ38364755
Neuronal nitric oxide synthase is expressed in the axotomized ganglion cells of the rat retinaQ38519571
Mini-Review: Impaired Axonal Transport and GlaucomaQ38540617
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectretinal ganglion cellQ927337
nerve growth factorsQ98072643
P304page(s)4314
P577publication date2019-01-01
2019-09-03
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleTarget-Derived Neurotrophic Factor Deprivation Puts Retinal Ganglion Cells on Death Row: Cold Hard Evidence and Caveats
P478volume20

Search more.