| P2093 | author name string | Huilin Li | |
| | Yujia Ying | |
| P2860 | cites work | The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 |
| | Insight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profiling | Q28076999 |
| | Ion activation methods for tandem mass spectrometry | Q28287604 |
| | Ion Activation Methods for Peptides and Proteins | Q29391863 |
| | Parsing Disease-relevant Protein Modifications from Epiphenomena: Perspective on the Structural Basis of SOD1-Mediated ALS. | Q30101060 |
| | Pepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis | Q30278544 |
| | Molecular clocks | Q30327762 |
| | Lens β-crystallins: the role of deamidation and related modifications in aging and cataract. | Q30360031 |
| | Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry. | Q30378926 |
| | Recent advances in mass spectrometric analysis of protein deamidation. | Q30383499 |
| | Independent highly sensitive characterization of asparagine deamidation and aspartic acid isomerization by sheathless CZE-ESI-MS/MS. | Q30384596 |
| | Identification of Sequence Similarities among Isomerization Hotspots in Crystallin Proteins | Q30399065 |
| | Bottom up proteomics data analysis strategies to explore protein modifications and genomic variants. | Q30893312 |
| | Separation of isomeric peptides using electrospray ionization/high-resolution ion mobility spectrometry | Q33421447 |
| | Age-dependent deamidation of lifelong proteins in the human lens | Q33522366 |
| | Glutamine deamidation: differentiation of glutamic acid and gamma-glutamic acid in peptides by electron capture dissociation | Q33857391 |
| | Are ancient proteins responsible for the age-related decline in health and fitness? | Q33905239 |
| | Deamidation of human proteins | Q33947742 |
| | Isoaspartate formation and neurodegeneration in Alzheimer's disease | Q34060440 |
| | Top-down study of β2-microglobulin deamidation | Q34219743 |
| | Racemization of two proteins over our lifespan: deamidation of asparagine 76 in γS crystallin is greater in cataract than in normal lenses across the age range | Q34244542 |
| | Identification of amino acid epimerization and isomerization in crystallin proteins by tandem LC-MS | Q34300357 |
| | Age-dependent deamidation of asparagine residues in proteins | Q34348827 |
| | Molecular ageing of alpha- and Beta-synucleins: protein damage and repair mechanisms. | Q34695506 |
| | Radio-frequency-free cell for electron capture dissociation in tandem mass spectrometry | Q34732924 |
| | Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides | Q35015203 |
| | Integrated strong cation-exchange hybrid monolith coupled with capillary zone electrophoresis and simultaneous dynamic pH junction for large-volume proteomic analysis by mass spectrometry | Q35376902 |
| | Mildly acidic conditions eliminate deamidation artifact during proteolysis: digestion with endoprotease Glu-C at pH 4.5. | Q35889468 |
| | Intracerebral Injection of Metal-Binding Domain of Aβ Comprising the Isomerized Asp7 Increases the Amyloid Burden in Transgenic Mice | Q35913908 |
| | Characterization of deamidation of barstar using electrospray ionization quadrupole time-of-flight mass spectrometry, which stabilizes an equilibrium unfolding intermediate | Q36111510 |
| | Deamidation: Differentiation of aspartyl from isoaspartyl products in peptides by electron capture dissociation | Q36476874 |
| | Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues | Q36596625 |
| | Biochemistry of amino acid racemization and clinical application to musculoskeletal disease | Q36626182 |
| | Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer's disease with cerebrovascular disease | Q36694586 |
| | Rate of Asparagine Deamidation in a Monoclonal Antibody Correlating with Hydrogen Exchange Rate at Adjacent Downstream Residues. | Q47828405 |
| | A Comparison of Common Mass Spectrometry Approaches for Paleoproteomics | Q48134508 |
| | An integrated native mass spectrometry and top-down proteomics method that connects sequence to structure and function of macromolecular complexes | Q48186934 |
| | Top-Down Proteomics: Ready for Prime Time? | Q48262177 |
| | Characterization of Glutamine Deamidation by Long-Length Electrostatic Repulsion-Hydrophilic Interaction Chromatography-Tandem Mass Spectrometry (LERLIC-MS/MS) in Shotgun Proteomics | Q48448529 |
| | Exploring Biological and Geological Age-related Changes through Variations in Intra- and Intertooth Proteomes of Ancient Dentine | Q50093080 |
| | A High-Throughput Bioluminescent Assay to Monitor the Deamidation of Asparagine and Isomerization of Aspartate Residues in Therapeutic Proteins and Antibodies. | Q50860057 |
| | Charge variants characterization of a monoclonal antibody by ion exchange chromatography coupled on-line to native mass spectrometry: Case study after a long-term storage at +5°C. | Q50869919 |
| | Identification of multiple sources of the acidic charge variants in an IgG1 monoclonal antibody. | Q50903364 |
| | Distinguishing d- and l-aspartic and isoaspartic acids in amyloid β peptides with ultrahigh resolution ion mobility spectrometry. | Q50920962 |
| | A structural and functional study of Gln147 deamidation in αA-crystallin, a site of modification in human cataract. | Q50990718 |
| | Exploiting charge differences for the analysis of challenging post-translational modifications by capillary electrophoresis-mass spectrometry. | Q51145652 |
| | One-shot LC-MS/MS analysis of post-translational modifications including oxidation and deamidation of rat lens α- and β-crystallins induced by γ-irradiation. | Q51531170 |
| | Quantification of in vivo site-specific Asp isomerization and Asn deamidation of mAbs in animal serum using IP-LC-MS. | Q51651469 |
| | Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface | Q92214816 |
| | Degenerative protein modifications in the aging vasculature and central nervous system: A problem shared is not always halved | Q92217679 |
| | Negative charge at aspartate 151 is important for human lens αA-crystallin stability and chaperone function | Q92229700 |
| | An Automated and Qualified Platform Method for Site-Specific Succinimide and Deamidation Quantitation Using Low-pH Peptide Mapping | Q92369542 |
| | A Cyclic Ion Mobility-Mass Spectrometry System | Q92374949 |
| | Using bispecific antibodies in forced degradation studies to analyze the structure-function relationships of symmetrically and asymmetrically modified antibodies | Q92509360 |
| | Analysis of four therapeutic monoclonal antibodies by online capillary isoelectric focusing directly coupled to quadrupole time-of-flight mass spectrometry | Q92588504 |
| | A single Asp isomer substitution in an αA-crystallin-derived peptide induces a large change in peptide properties | Q92600219 |
| | Ionisation bias undermines the use of matrix-assisted laser desorption/ionisation for estimating peptide deamidation: Synthetic peptide studies demonstrate electrospray ionisation gives more reliable response ratios | Q92600654 |
| | A next generation setup for pre-fractionation of non-denatured proteins reveals diverse albumin proteoforms each carrying several post-translational modifications | Q92603131 |
| | Deamidation Can Compromise Antibody Colloidal Stability and Enhance Aggregation in a pH-Dependent Manner | Q92648356 |
| | Characterization of IgG1 Fc Deamidation at Asparagine 325 and Its Impact on Antibody-dependent Cell-mediated Cytotoxicity and FcγRIIIa Binding | Q92669076 |
| | All Ion Differential Analysis Refines the Detection of Terminal and Internal Diagnostic Fragment Ions for the Characterization of Biologics Product-Related Variants and Impurities by Middle-down Mass Spectrometry | Q92678589 |
| | Engineering an anti-CD52 antibody for enhanced deamidation stability | Q92745836 |
| | Streamlining the polishing step development process via physicochemical characterization of monoclonal antibody aggregates | Q92894153 |
| | Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer | Q93057441 |
| | Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments | Q93089051 |
| | Spontaneous Isomerization of Long-Lived Proteins Provides a Molecular Mechanism for the Lysosomal Failure Observed in Alzheimer's Disease | Q93089168 |
| | Protein interactome of the deamidase phosphoribosylformylglycinamidine synthetase (PFAS) by LC-MS/MS | Q93108356 |
| | Altered Protein Dynamics and Increased Aggregation of Human γS-Crystallin Due to Cataract-Associated Deamidations | Q93142025 |
| | Heterogeneity assessment of antibody-derived therapeutics at the intact and middle-up level by low-flow sheathless capillary electrophoresis-mass spectrometry | Q93157652 |
| | Analysis of Glutamine Deamidation: Products, Pathways, and Kinetics | Q93195266 |
| | A Middle-Up Approach with Online Capillary Isoelectric Focusing/Mass Spectrometry for In-Depth Characterization of Cetuximab Charge Heterogeneity | Q93207167 |
| | Does deamidation of islet amyloid polypeptide accelerate amyloid fibril formation? | Q93357051 |
| | Age-related changes in human crystallins determined from comparative analysis of post-translational modifications in young and aged lens: does deamidation contribute to crystallin insolubility? | Q36876664 |
| | Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry | Q37327298 |
| | Developability studies before initiation of process development: improving manufacturability of monoclonal antibodies | Q37364361 |
| | Site-specific characterization of (D)-amino acid containing peptide epimers by ion mobility spectrometry | Q37724249 |
| | Differentiation of isomeric amino acid residues in proteins and peptides using mass spectrometry. | Q37982946 |
| | Hydrogen deuterium mass spectrometry in drug discovery | Q38550273 |
| | Isomerization of aspartyl residues in crystallins and its influence upon cataract | Q38566934 |
| | Two-dimensional capillary zone electrophoresis-mass spectrometry for the characterization of intact monoclonal antibody charge variants, including deamidation products | Q38628030 |
| | Chromatographic, Electrophoretic, and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals | Q38656541 |
| | Mass Spectrometry Applied to Bottom-Up Proteomics: Entering the High-Throughput Era for Hypothesis Testing | Q38799342 |
| | Unbiased in-depth characterization of CEX fractions from a stressed monoclonal antibody by mass spectrometry | Q38852892 |
| | Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies | Q38915146 |
| | Hydrogen deuterium exchange mass spectrometry in biopharmaceutical discovery and development - A review. | Q38962917 |
| | Glutamine deamidation: an indicator of antiquity, or preservational quality? | Q40187189 |
| | Deamidation of Human γS-Crystallin Increases Attractive Protein Interactions: Implications for Cataract | Q40754367 |
| | Differences in solution dynamics between lens β-crystallin homodimers and heterodimers probed by hydrogen-deuterium exchange and deamidation | Q40767353 |
| | Fast Comparative Structural Characterization of Intact Therapeutic Antibodies Using Hydrogen-Deuterium Exchange and Electron Transfer Dissociation | Q40994262 |
| | Quantitative proteomic study of Aspergillus Fumigatus secretome revealed deamidation of secretory enzymes. | Q41337965 |
| | The Separation and Quantitation of Peptides with and without Oxidation of Methionine and Deamidation of Asparagine Using Hydrophilic Interaction Liquid Chromatography with Mass Spectrometry (HILIC-MS). | Q41692568 |
| | Rapid survey of four Asp isomers in disease-related proteins by LC-MS combined with commercial enzymes | Q41723378 |
| | Analysis of isoaspartic Acid by selective proteolysis with Asp-N and electron transfer dissociation mass spectrometry | Q41970463 |
| | Simultaneous monitoring of oxidation, deamidation, isomerization, and glycosylation of monoclonal antibodies by liquid chromatography-mass spectrometry method with ultrafast tryptic digestion | Q42081044 |
| | In-Source Decay Characterization of Isoaspartate and β-Peptides | Q42225476 |
| | Deamidation of alpha-synuclein | Q42635838 |
| | Proteins and their modifications in a medieval mummy | Q42676562 |
| | Enhanced separation and characterization of deamidated peptides with RP-ERLIC-based multidimensional chromatography coupled with tandem mass spectrometry | Q43964541 |
| | Amide molecular clocks in drosophila proteins: potential regulators of aging and other processes | Q44828835 |
| | Structure-dependent nonenzymatic deamidation of glutaminyl and asparaginyl pentapeptides | Q44893900 |
| | High Resolution CZE-MS Quantitative Characterization of Intact Biopharmaceutical Proteins: Proteoforms of Interferon-β1. | Q45291742 |
| | Integrated Bottom-Up and Top-Down Liquid Chromatography-Mass Spectrometry for Characterization of Recombinant Human Growth Hormone Degradation Products | Q45305252 |
| | Sequence and Solution Effects on the Prevalence of d-Isomers Produced by Deamidation. | Q45969140 |
| | Automated Affinity Capture and On-Tip Digestion to Accurately Quantitate in Vivo Deamidation of Therapeutic Antibodies. | Q46155984 |
| | Deamidation of asparagine residues: direct hydrolysis versus succinimide-mediated deamidation mechanisms. | Q46157873 |
| | Method to differentiate asn deamidation that occurred prior to and during sample preparation of a monoclonal antibody | Q46203892 |
| | Fast and Effective Ion Mobility-Mass Spectrometry Separation of d-Amino-Acid-Containing Peptides | Q46293786 |
| | Capillary electrophoresis-tandem mass spectrometry as a highly selective tool for the compositional and site-specific assessment of multiple peptide-deamidation. | Q46332180 |
| | Minimizing Laboratory-Induced Decay in Bone Proteomics. | Q46424106 |
| | Characterization of charge variants of a monoclonal antibody using weak anion exchange chromatography at subunit levels | Q46440116 |
| | Chemical modifications of amyloid-β(1-42) have a significant impact on the repertoire of brain amyloid-β(1-42) binding proteins. | Q46518156 |
| | LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma | Q46617526 |
| | Characterization of intact protein conjugates and biopharmaceuticals using ion-exchange chromatography with online detection by native electrospray ionization mass spectrometry and top-down tandem mass spectrometry | Q46671177 |
| | Differentiation of aspartic and isoaspartic acids using electron transfer dissociation | Q46843070 |
| | Paenidase, a novel D-aspartyl endopeptidase from Paenibacillus sp. B38: purification and substrate specificity | Q46923280 |
| | Detecting deamidation products in proteins by electron capture dissociation | Q46944243 |
| | Discriminating D-amino acid-containing peptide epimers by radical-directed dissociation mass spectrometry | Q46964322 |
| | Identification of ᴅ-amino acid-containing peptides in human serum | Q47106292 |
| | The Role of Electron Transfer Dissociation in Modern Proteomics | Q47111216 |
| | Top-down characterization of endogenous protein complexes with native proteomics | Q47409854 |
| | Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins. | Q47700311 |
| | A Fluorescence-Based High-Throughput Coupled Enzymatic Assay for Quantitation of Isoaspartate in Proteins and Peptides. | Q51682998 |
| | Characterization of Recombinant Monoclonal Antibody Charge Variants Using OFFGEL Fractionation, Weak Anion Exchange Chromatography, and Mass Spectrometry. | Q51743053 |
| | Deamidation of N76 in human γS-crystallin promotes dimer formation. | Q53363641 |
| | Ultrasensitive Characterization of Charge Heterogeneity of Therapeutic Monoclonal Antibodies Using Strong Cation Exchange Chromatography Coupled to Native Mass Spectrometry | Q57033298 |
| | Monitoring of Deamidation and Lanthionine Formation in Recombinant Mugwort Allergen by Capillary Zone Electrophoresis (CZE)-UV and Transient Capillary Isotachophoresis-CZE-Electrospray Ionization-TOF-MS | Q57033371 |
| | Assessment of susceptible chemical modification sites of trastuzumab and endogenous human immunoglobulins at physiological conditions | Q57146442 |
| | Comprehensive characterisation of the heterogeneity of adalimumab via charge variant analysis hyphenated on-line to native high resolution Orbitrap mass spectrometry | Q57181541 |
| | Evaluation of the Effect of Trypsin Digestion Buffers on Artificial Deamidation | Q57236340 |
| | Protein deamidation in biopharmaceutical manufacture: understanding, control and impact | Q57449695 |
| | Amyloid-β containing isoaspartate 7 as potential biomarker and drug target in Alzheimer's disease | Q57721654 |
| | Intact monoclonal antibodies separation and analysis by sheathless capillary electrophoresis-mass spectrometry | Q57796941 |
| | Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function | Q57817264 |
| | Charge variant native mass spectrometry benefits mass precision and dynamic range of monoclonal antibody intact mass analysis | Q58589011 |
| | Implications of Metal Binding and Asparagine Deamidation for Amyloid Formation | Q58765987 |
| | The use of in-strip digestion for fast proteomic analysis on tear fluid from dry eye patients | Q58802532 |
| | Coformulation of Broadly Neutralizing Antibodies 3BNC117 and PGT121: Analytical Challenges During Preformulation Characterization and Storage Stability Studies | Q59797645 |
| | Fine Endmesolithic fish caviar meal discovered by proteomics in foodcrusts from archaeological site Friesack 4 (Brandenburg, Germany) | Q60049734 |
| | The effects of demineralisation and sampling point variability on the measurement of glutamine deamidation in type I collagen extracted from bone | Q60540589 |
| | Structural and functional consequences of age-related isomerization in α-crystallins | Q64105433 |
| | Separation of β-Amyloid Tryptic Peptide Species with Isomerized and Racemized l-Aspartic Residues with Ion Mobility in Structures for Lossless Ion Manipulations. | Q64956456 |
| | Deamidation and isomerization liability analysis of 131 clinical-stage antibodies. | Q64982156 |
| | Complementary middle-down and intact monoclonal antibody proteoform characterization by capillary zone electrophoresis - mass spectrometry. | Q64985885 |
| | Deamidation of glutaminyl residues: dependence on pH, temperature, and ionic strength | Q68776856 |
| | Quantitating the relative abundance of isoaspartyl residues in deamidated proteins by electron capture dissociation | Q80334852 |
| | Novel application of electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) in shotgun proteomics: comprehensive profiling of rat kidney proteome | Q84181530 |
| | Deamidation in ricin studied by capillary zone electrophoresis- and liquid chromatography-mass spectrometry | Q86157209 |
| | Identification of Isomeric Aspartate residues in βB2-crystallin from Aged Human Lens | Q88358426 |
| | High throughput detection of deamidation using S-(5'-adenosyl)-l-homocysteine hydrolase and a fluorogenic reagent | Q88629375 |
| | Use of In Vitro Systems To Model In Vivo Degradation of Therapeutic Monoclonal Antibodies | Q88962712 |
| | Online Removal of Sodium Dodecyl Sulfate via Weak Cation Exchange in Liquid Chromatography-Mass Spectrometry Based Proteomics | Q89059232 |
| | Proteomic Analysis of Aqueous Humor from Primary Open Angle Glaucoma Patients on Drug Treatment Revealed Altered Complement Activation Cascade | Q89100912 |
| | Combination of intact, middle-up and bottom-up levels to characterize 7 therapeutic monoclonal antibodies by capillary electrophoresis - Mass spectrometry | Q89469043 |
| | Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry | Q89475588 |
| | Application of CE-MS for the analysis of histones and histone modifications | Q89515859 |
| | TUTORIAL: ION ACTIVATION IN TANDEM MASS SPECTROMETRY USING ULTRA-HIGH RESOLUTION INSTRUMENTATION | Q89645959 |
| | Characterization and quantification of succinimide using peptide mapping under low-pH conditions and hydrophobic interaction chromatography | Q90024811 |
| | Comprehensive Detection of Isopeptides between Human Tissue Transglutaminase and Gluten Peptides | Q90227760 |
| | Effect of Aluminum Adjuvant and Preservatives on Structural Integrity and Physicochemical Stability Profiles of Three Recombinant Subunit Rotavirus Vaccine Antigens | Q90564961 |
| | Multi-Attribute Method for Quality Control of Therapeutic Proteins | Q90743535 |
| | Streamlined Characterization of an Antibody-Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry | Q90764550 |
| | Ion Activation Methods for Peptides and Proteins | Q91008688 |
| | Unique Impacts of Methionine Oxidation, Tryptophan Oxidation, and Asparagine Deamidation on Antibody Stability and Aggregation | Q91069919 |
| | Molecular basis for chirality-regulated Aβ self-assembly and receptor recognition revealed by ion mobility-mass spectrometry | Q91151379 |
| | A systematic approach for analysis and characterization of mispairing in bispecific antibodies with asymmetric architecture | Q91177710 |
| | Rapid Prediction of Deamidation Rates of Proteins to Assess Their Long-Term Stability Using Hydrogen Exchange-Mass Spectrometry | Q91233305 |
| | Improved Electrophoretic Separation to Assist the Monitoring of Bcl-xL Post-Translational Modifications | Q91251767 |
| | Proteomic and Unbiased Post-Translational Modification Profiling of Amyloid Plaques and Surrounding Tissue in a Transgenic Mouse Model of Alzheimer's Disease | Q91467860 |
| | Multiplexed Middle-Down Mass Spectrometry as a Method for Revealing Light and Heavy Chain Connectivity in a Monoclonal Antibody | Q91721835 |
| | Top-down Mass Spectrometry of Sarcomeric Protein Post-translational Modifications from Non-human Primate Skeletal Muscle | Q92133168 |
| | Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity | Q92210130 |
| P4510 | describes a project that uses | mass spectrometry | Q180809 |
| P577 | publication date | 2020-06-13 | |
| P1433 | published in | Methods | Q6823859 |
| P1476 | title | Recent Progress in the Analysis of Protein Deamidation Using Mass Spectrometry | |