| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2001PNAS...98..944R |
| P356 | DOI | 10.1073/PNAS.98.3.944 |
| P932 | PMC publication ID | 14689 |
| P698 | PubMed publication ID | 11158575 |
| P5875 | ResearchGate publication ID | 12170311 |
| P2093 | author name string | Robinson NE | |
| Robinson AB | |||
| P2860 | cites work | Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins | Q28618536 |
| Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation | Q30406473 | ||
| Controlled deamidation of peptides and proteins: an experimental hazard and a possible biological timer | Q33699193 | ||
| Deamidation In Vivo of an Asparagine Residue of Rabbit Muscle Aldolase | Q34714805 | ||
| Evolution and the Distribution of Glutaminyl and Asparaginyl Residues in Proteins | Q37435122 | ||
| Distribution of glutamine and asparagine residues and their near neighbors in peptides and proteins | Q37603553 | ||
| Molecular clocks, molecular profiles, and optimum diets: Three approaches to the problem of aging | Q39794179 | ||
| Deamidation of glutaminyl and asparaginyl residues in peptides and proteins. | Q39902554 | ||
| Specific glutamine and asparagine residues of gamma-S crystallin are resistant to in vivo deamidation | Q40874506 | ||
| Primary sequence dependence of the deamidation of rabbit muscle aldolase | Q41516914 | ||
| Sequence dependent deamidation rates for model peptides of hen egg-white lysozyme. | Q43833644 | ||
| The microheterogeneity of the mammalian H1(0) histone. Evidence for an age-dependent deamidation | Q48462956 | ||
| Terminal marking of triosephosphate isomerase: consequences of deamidation. | Q50757994 | ||
| Effect of the three-dimensional structure on the deamidation reaction of ribonuclease A | Q57959178 | ||
| Sequence dependent deamidation rates for model peptides of cytochrome C | Q68695853 | ||
| Deamidation of glutaminyl residues: dependence on pH, temperature, and ionic strength | Q68776856 | ||
| Sequence dependent deamidation rates for model peptides of histone IV | Q68830073 | ||
| Rates of nonenzymic deamidation of glutaminyl and asparaginyl residues in pentapeptides | Q69625395 | ||
| Multiple forms of cytochrome c in the rat. Precursor-product relationship between the main component Cy I and the minor components Cy II and Cy 3 in vivo | Q72039738 | ||
| Microheterogeneity of recombinant human phenylalanine hydroxylase as a result of nonenzymatic deamidations of labile amide containing amino acids. Effects on catalytic and stability properties | Q73023867 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 944-949 | |
| P577 | publication date | 2001-01-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Molecular clocks | |
| P478 | volume | 98 |
| Q46575307 | A Computational Study of the Mechanism of Succinimide Formation in the Asn-His Sequence: Intramolecular Catalysis by the His Side Chain. |
| Q40443534 | A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation |
| Q36675136 | A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides |
| Q64066982 | A post-translational modification of human Norovirus capsid protein attenuates glycan binding |
| Q30317896 | A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues |
| Q54798246 | A six-gene phylogenetic overview of Basidiomycota and allied phyla with estimated divergence times of higher taxa and a phyloproteomics perspective |
| Q37685871 | Accurate identification of deamidated peptides in global proteomics using a quadrupole orbitrap mass spectrometer |
| Q34049032 | Age estimation of museum wool textiles from Ovis aries using deamidation rates utilizing matrix-assisted laser desorption/ionization time-of-flight mass spectrometry |
| Q35119508 | Aging as war between chemical and biochemical processes: Protein methylation and the recognition of age-damaged proteins for repair |
| Q36984283 | An 18O-labeling assisted LC/MS method for assignment of aspartyl/isoaspartyl products from Asn deamidation and Asp isomerization in proteins |
| Q44746331 | An oncogenic tyrosine kinase inhibits DNA repair and DNA-damage-induced Bcl-xL deamidation in T cell transformation |
| Q44239836 | Analysis of isoaspartate in a recombinant monoclonal antibody and its charge isoforms |
| Q41970463 | Analysis of isoaspartic Acid by selective proteolysis with Asp-N and electron transfer dissociation mass spectrometry |
| Q44367201 | Analysis of the subunit composition of complex I from bovine heart mitochondria |
| Q36358797 | Asparagine deamidation reduces DNA-binding affinity of the Drosophila melanogaster Scr homeodomain |
| Q44665427 | Aspartic acid racemization: evidence for marked longevity of elastin in human skin. |
| Q39252529 | Assessing analytical methods to monitor isoAsp formation in monoclonal antibodies |
| Q38717942 | Assessment of chemical modifications of sites in the CDRs of recombinant antibodies: Susceptibility vs. functionality of critical quality attributes |
| Q30331771 | Atomic resolution structure of a succinimide intermediate in E.coli CheY. |
| Q44173674 | Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage |
| Q48388591 | Biochemical characterization of vitreous and cardiac amyloid in Ile84Ser transthyretin amyloidosis |
| Q46756200 | Both chloroplastic and cytosolic phosphofructoaldolase isozymes are present in the pea leaf nucleus |
| Q54219436 | CNF1-like deamidase domains: common Lego bricks among cancer-promoting immunomodulatory bacterial virulence factors. |
| Q36111510 | Characterization of deamidation of barstar using electrospray ionization quadrupole time-of-flight mass spectrometry, which stabilizes an equilibrium unfolding intermediate |
| Q43764396 | Characterization of therapeutic monoclonal antibodies reveals differences between in vitro and in vivo time-course studies |
| Q42153052 | Chemical and functional aspects of posttranslational modification of proteins |
| Q53622461 | Co-occurrence of both L-asparaginase subtypes in Arabidopsis: At3g16150 encodes a K+-dependent L-asparaginase. |
| Q37080677 | Combining results from lectin affinity chromatography and glycocapture approaches substantially improves the coverage of the glycoproteome |
| Q41913558 | Comparison of the in vitro and in vivo stability of a succinimide intermediate observed on a therapeutic IgG1 molecule |
| Q92942477 | Computational Studies on the Nonenzymatic Deamidation Mechanisms of Glutamine Residues |
| Q36131709 | Deamidation Reactions of Asparagine- and Glutamine-Containing Dipeptides Investigated by Ion Spectroscopy. |
| Q48152649 | Deamidation Slows Curli Amyloid-Protein Aggregation. |
| Q41814945 | Deamidation accelerates amyloid formation and alters amylin fiber structure |
| Q64982156 | Deamidation and isomerization liability analysis of 131 clinical-stage antibodies. |
| Q108503122 | Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif |
| Q57817264 | Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function |
| Q50047009 | Deamidation of Protonated Asparagine-Valine Investigated by a Combined Spectroscopic, Guided Ion Beam, and Theoretical Study. |
| Q42635838 | Deamidation of alpha-synuclein |
| Q33947742 | Deamidation of human proteins |
| Q35896428 | Deamidation reactions of protonated asparagine and glutamine investigated by ion spectroscopy. |
| Q36476874 | Deamidation: Differentiation of aspartyl from isoaspartyl products in peptides by electron capture dissociation |
| Q30884168 | Deamidations in recombinant human phenylalanine hydroxylase. Identification of labile asparagine residues and functional characterization of Asn --> Asp mutant forms |
| Q38901019 | Detection, evaluation and minimization of nonenzymatic deamidation in proteomic sample preparation |
| Q38281208 | Differentiating N-terminal aspartic and isoaspartic acid residues in peptides. |
| Q30986578 | Differentiation and Semiquantitative Analysis of an Isoaspartic Acid in Human α-Crystallin by Postsource Decay in a Curved Field Reflectron |
| Q37982946 | Differentiation of isomeric amino acid residues in proteins and peptides using mass spectrometry. |
| Q35555590 | Does deamidation cause protein unfolding? A top-down tandem mass spectrometry study |
| Q26830466 | Early implementation of QbD in biopharmaceutical development: a practical example |
| Q37361931 | Effect of N-1 and N-2 residues on peptide deamidation rate in solution and solid state |
| Q30378308 | Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody. |
| Q50974872 | Effects of UV radiation on the lipids and proteins of bacteria studied by mid-infrared spectroscopy. |
| Q33224077 | Effects of spontaneous deamidation on the cytotoxic activity of the Bacillus anthracis protective antigen |
| Q35043190 | Electron transfer dissociation with supplemental activation to differentiate aspartic and isoaspartic residues in doubly charged peptide cations. |
| Q46114334 | Elucidation of degradants in acidic peak of cation exchange chromatography in an IgG1 monoclonal antibody formed on long-term storage in a liquid formulation |
| Q28074848 | Emerging Roles of Protein Deamidation in Innate Immune Signaling |
| Q40135575 | Energetics-based protein profiling on a proteomic scale: identification of proteins resistant to proteolysis |
| Q37853324 | Engineering the variable region of therapeutic IgG antibodies. |
| Q47552404 | Estimation of Chronological Age from Postmortem Tissues Based on Amino Acid Racemization. |
| Q33701885 | Evidence of the involvement of asparagine deamidation in the formation of cyclodextrin glycosyltransferase isoforms in Paenibacillus sp. RB01. |
| Q85041697 | Generation of a humanized anti-glypican 3 antibody by CDR grafting and stability optimization |
| Q38092837 | Getting away with murder: how does the BCL-2 family of proteins kill with immunity? |
| Q40187189 | Glutamine deamidation: an indicator of antiquity, or preservational quality? |
| Q42287023 | Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing |
| Q33293308 | Haptoglobin comprises about 10% of granule protein extracted from bovine granulocytes isolated from healthy cattle |
| Q91646668 | Hypoxia-Induced Degenerative Protein Modifications Associated with Aging and Age-Associated Disorders |
| Q42076718 | Identification of aspartic and isoaspartic acid residues in amyloid beta peptides, including Abeta1-42, using electron-ion reactions |
| Q30384596 | Independent highly sensitive characterization of asparagine deamidation and aspartic acid isomerization by sheathless CZE-ESI-MS/MS. |
| Q51581444 | Ion-Exchange Chromatography to Analyze Components of a Clostridium difficile Vaccine. |
| Q30319326 | Isoaspartate-containing amyloid precursor protein-derived peptides alter efficacy and specificity of potential beta-secretases |
| Q50651934 | LERLIC-MS/MS for In-depth Characterization and Quantification of Glutamine and Asparagine Deamidation in Shotgun Proteomics. |
| Q33568235 | Large-scale analysis of post-translational modifications in E. coli under glucose-limiting conditions |
| Q92344983 | Machine Learning Enables Accurate Prediction of Asparagine Deamidation Probability and Rate |
| Q35015203 | Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides |
| Q43662252 | Mass spectrometric evaluation of synthetic peptides as primary structure models for peptide and protein deamidation |
| Q34628096 | Mass spectrometric peptide analysis of 2DE-separated mouse spinal cord and rat hippocampus proteins suggests an NGxG motif of importance for in vivo deamidation |
| Q91633980 | Mechanism of protein cleavage at asparagine leading to protein-protein cross-links |
| Q35935173 | Mechanistic Analysis of the Effect of Deamidation on the Immunogenicity of Anthrax Protective Antigen |
| Q33916089 | Monocyte adhesion to atherosclerotic matrix proteins is enhanced by Asn-Gly-Arg deamidation |
| Q43276079 | Multivariate analysis of the sequence dependence of asparagine deamidation rates in peptides |
| Q44974666 | N+1 Engineering of an Aspartate Isomerization Hotspot in the Complementarity-Determining Region of a Monoclonal Antibody |
| Q37388959 | N- and O-glycosylation in the murine synaptosome |
| Q36095201 | N-linked glycosite profiling and use of Skyline as a platform for characterization and relative quantification of glycans in differentiating xylem of Populus trichocarpa |
| Q102060953 | NGOME-Lite: Proteome-wide prediction of spontaneous protein deamidation highlights differences between taxa |
| Q38790836 | Negative ion cleavages of (M-H)(-) anions of peptides. Part 3. Post-translational modifications |
| Q89450487 | Off-pathway 3D-structure provides protection against spontaneous Asn/Asp isomerization: shielding proteins Achilles heel |
| Q38900143 | Old Proteins in Man: A Field in its Infancy |
| Q61813228 | Optimised methods (SDS/PAGE and LC-MS) reveal deamidation in all examined transglutaminase-mediated reactions |
| Q37727752 | Overcoming challenges and opening new opportunities in glycoproteomics |
| Q44607670 | Overexpression of l-Isoaspartate O-Methyltransferase in Escherichia coli Increases Heat Shock Survival by a Mechanism Independent of Methyltransferase Activity |
| Q37563576 | Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling |
| Q52929895 | Palaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting. |
| Q46489987 | Post-translational modifications of chicken myelin basic protein charge components. |
| Q24304928 | Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission |
| Q35870617 | Prediction of Spontaneous Protein Deamidation from Sequence-Derived Secondary Structure and Intrinsic Disorder. |
| Q43419013 | Prediction of primary structure deamidation rates of asparaginyl and glutaminyl peptides through steric and catalytic effects |
| Q35248578 | Prediction of protein deamidation rates from primary and three-dimensional structure |
| Q94956418 | Profiling the 'deamidome' of complex biosamples using mixed-mode chromatography-coupled tandem mass spectrometry |
| Q38667917 | Protein asparagine deamidation prediction based on structures with machine learning methods |
| Q34024381 | Protein deamidation |
| Q57449695 | Protein deamidation in biopharmaceutical manufacture: understanding, control and impact |
| Q36028759 | Protein post-translational modifications and misfolding: new concepts in heart failure |
| Q37154147 | Quantification of angiotensin II-regulated proteins in urine of patients with polycystic and other chronic kidney diseases by selected reaction monitoring. |
| Q80334852 | Quantitating the relative abundance of isoaspartyl residues in deamidated proteins by electron capture dissociation |
| Q33231198 | Quantitative measurement of deamidation in lens betaB2-crystallin and peptides by direct electrospray injection and fragmentation in a Fourier transform mass spectrometer |
| Q91233305 | Rapid Prediction of Deamidation Rates of Proteins to Assess Their Long-Term Stability Using Hydrogen Exchange-Mass Spectrometry |
| Q96438342 | Recent Progress in the Analysis of Protein Deamidation Using Mass Spectrometry |
| Q92539618 | Recombinant Subunit Rotavirus Trivalent Vaccine Candidate: Physicochemical Comparisons and Stability Evaluations of Three Protein Antigens |
| Q31101047 | Recombinant p53 displays heterogeneity during isoelectric focusing |
| Q41048721 | Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain |
| Q28473640 | Retracted: Protein Isoaspartate Methyltransferase Prevents Apoptosis Induced by Oxidative Stress in Endothelial Cells: Role of Bcl-Xl Deamidation and Methylation |
| Q98463585 | Revising the mechanism of p75NTR activation: intrinsically monomeric state of death domains invokes the "helper" hypothesis |
| Q45969140 | Sequence and Solution Effects on the Prevalence of d-Isomers Produced by Deamidation. |
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| Q34041520 | Structural and functional roles of deamidation of N146 and/or truncation of NH2- or COOH-termini in human αB-crystallin. |
| Q30373836 | Structural effects of protein aging: terminal marking by deamidation in human triosephosphate isomerase. |
| Q65000083 | Structure Based Prediction of Asparagine Deamidation Propensity in Monoclonal Antibodies. |
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| Q44893900 | Structure-dependent nonenzymatic deamidation of glutaminyl and asparaginyl pentapeptides |
| Q47700311 | Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins. |
| Q33703464 | Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning |
| Q38801839 | Systemic and tumor-targeted delivery of siRNA by cyclic NGR and isoDGR motif-containing peptides |
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| Q34264152 | The conformational locking of asparagine. |
| Q39937281 | The microRNA 15a/16-1 cluster down-regulates protein repair isoaspartyl methyltransferase in hepatoma cells: implications for apoptosis regulation |
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| Q33814180 | Tissue transglutaminase-mediated glutamine deamidation of beta-amyloid peptide increases peptide solubility, whereas enzymatic cross-linking and peptide fragmentation may serve as molecular triggers for rapid peptide aggregation |
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| Q37373293 | Toward proteome-scale identification and quantification of isoaspartyl residues in biological samples. |
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| Q41345453 | Unexpected functional implication of a stable succinimide in the structural stability of Methanocaldococcus jannaschii glutaminase. |
| Q42742487 | Use of 18O labels to monitor deamidation during protein and peptide sample processing |
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