Organoarsenicals inhibit bacterial peptidoglycan biosynthesis by targeting the essential enzyme MurA

scientific article published on 27 April 2020

Organoarsenicals inhibit bacterial peptidoglycan biosynthesis by targeting the essential enzyme MurA is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CHEMOSPHERE.2020.126911
P932PMC publication ID7509207
P698PubMed publication ID32957300

P2093author name stringBarry P Rosen
Masafumi Yoshinaga
Luis D Garbinski
P2860cites workThe nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitorsQ46082809
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Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosisQ47904411
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Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA.Q54456599
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin.Q54590227
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A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate statesQ27642065
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A C⋅As lyase for degradation of environmental organoarsenical herbicides and animal husbandry growth promoters.Q33694625
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Synthesis and structure-activity relationship study of novel quinazolinone-based inhibitors of MurA.Q38745942
The organoarsenical biocycle and the primordial antibiotic methylarseniteQ38978392
Comparative toxicity of arsenic metabolites in human bladder cancer EJ-1 cells.Q39495284
Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic.Q40494874
The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA ReleaseQ40811390
ArsH is an organoarsenical oxidase that confers resistance to trivalent forms of the herbicide monosodium methylarsenate and the poultry growth promoter roxarsone.Q41268773
Organoarsenical Biotransformations by Shewanella putrefaciensQ41836751
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P304page(s)126911
P577publication date2020-04-27
P1433published inChemosphereQ749724
P1476titleOrganoarsenicals inhibit bacterial peptidoglycan biosynthesis by targeting the essential enzyme MurA
P478volume254

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