Rotavirus NSP1 localizes in the nucleus to disrupt PML nuclear bodies during infection

scientific article published on 26 April 2019

Rotavirus NSP1 localizes in the nucleus to disrupt PML nuclear bodies during infection is …
instance of (P31):
scholarly articleQ13442814
preprintQ580922

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P356DOI10.1101/619932

P2093author name stringMichelle M. Arnold
Samantha K. Murphy
P2860cites workRotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonismQ21090517
Rotavirus-encoded nonstructural protein 1 modulates cellular apoptotic machinery by targeting tumor suppressor protein p53Q24338301
MAVS protein is attenuated by rotavirus nonstructural protein 1Q24339399
Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3Q24555785
Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7Q24683021
Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus VirulenceQ26700161
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The Role of Nuclear Antiviral Factors against Invading DNA Viruses: The Immediate Fate of Incoming Viral GenomesQ28071373
Molecular mechanism behind rotavirus NSP1-mediated PI3 kinase activation: interaction between NSP1 and the p85 subunit of PI3 kinaseQ28280924
Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 ComplexQ28554481
Detection of a fourth orbivirus non-structural proteinQ28743968
Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5AQ33714369
Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8Q33812774
The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodiesQ33815705
Effect of intragenic rearrangement and changes in the 3' consensus sequence on NSP1 expression and rotavirus replicationQ33850456
Identification and characterization of a novel non-structural protein of bluetongue virusQ34126290
PML nuclear bodies: dynamic sensors of DNA damage and cellular stressQ34346231
Functional reorganization of promyelocytic leukemia nuclear bodies during BK virus infectionQ34576051
Diversity of interferon antagonist activities mediated by NSP1 proteins of different rotavirus strainsQ34742076
A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 GenomesQ34774721
Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP.Q35072342
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Rotavirus replication: plus-sense templates for double-stranded RNA synthesis are made in viroplasmsQ35122641
Rotavirus antagonism of the innate immune responseQ35260141
Characterising Non-Structural Protein NS4 of African Horse Sickness VirusQ35542582
A single-amino-acid polymorphism in reovirus protein μ2 determines repression of interferon signaling and modulates myocarditisQ35826485
Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution.Q36483624
Rotavirus variant replicates efficiently although encoding an aberrant NSP3 that fails to induce nuclear localization of poly(A)-binding proteinQ36525406
Deletion mapping of the rotavirus metalloprotein NS53 (NSP1): the conserved cysteine-rich region is essential for virus-specific RNA bindingQ36634428
Murine rotavirus genes encoding outer capsid proteins VP4 and VP7 are not major determinants of host range restriction and virulenceQ36644973
PML and PML nuclear bodies: implications in antiviral defenceQ36753891
Nuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signalingQ36760135
Rotavirus prevents the expression of host responses by blocking the nucleocytoplasmic transport of polyadenylated mRNAsQ36827188
Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin LigasesQ37002502
Silencing the alarms: Innate immune antagonism by rotavirus NSP1 and VP3Q37083338
Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunityQ37088604
Structural insights into the coupling of virion assembly and rotavirus replicationQ37167334
Rotavirus antagonizes cellular antiviral responses by inhibiting the nuclear accumulation of STAT1, STAT2, and NF-kappaB.Q37192229
Role of nuclear bodies in apoptosis signallingQ37235467
Variation in antagonism of the interferon response to rotavirus NSP1 results in differential infectivity in mouse embryonic fibroblastsQ37248029
New insights into the role of the subnuclear structure ND10 for viral infectionQ37262401
Rotavirus NSP1 protein inhibits interferon-mediated STAT1 activationQ37547591
The shift from low to high non-structural protein 1 expression in rotavirus-infected MA-104 cells.Q37674964
Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteinsQ37721763
Incoming human papillomavirus 16 genome is lost in PML protein-deficient HaCaT keratinocytes.Q38730491
Nondefective rotavirus mutants with an NSP1 gene which has a deletion of 500 nucleotides, including a cysteine-rich zinc finger motif-encoding region (nucleotides 156 to 248), or which has a nonsense codon at nucleotides 153-155.Q39874852
Replication of ICP0-null mutant herpes simplex virus type 1 is restricted by both PML and Sp100.Q40030711
Genomic concatemerization/deletion in rotaviruses: a new mechanism for generating rapid genetic change of potential epidemiological importanceQ40047940
Rotavirus NSP1 Requires Casein Kinase II-Mediated Phosphorylation for Hijacking of Cullin-RING LigasesQ40066025
Analysis of genetic factors related to preferential selection of the NSP1 gene segment observed in mixed infection and multiple passage of rotavirusesQ40268087
Herpes simplex virus type 1 genomes are associated with ND10 nuclear substructures in quiescently infected human fibroblastsQ41877073
Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infectionQ42019706
Analysis of the kinetics of transcription and replication of the rotavirus genome by RNA interferenceQ42233256
Correction: MAVS Protein Is Attenuated by Rotavirus Nonstructural Protein 1Q42398746
Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.Q42676601
Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.Q43076644
Permissive replication of homologous murine rotavirus in the mouse intestine is primarily regulated by VP4 and NSP1.Q43079549
Differences in plaque size and VP4 sequence found in SA11 virus clones having simian authentic VP4.Q45777266
Functional analysis of the heterologous NSP1 genes in the genetic background of simian rotavirus SA11.Q47930114
PML nuclear bodies: from architecture to functionQ88557822
P4510describes a project that usesPorcine rotavirus OSUQ112246255
Simian rotavirus A/SA11Q112242768
P921main subjectRotavirusQ164778
modulation by virus of host processQ14818042
Rotavirus non-structural protein 1Q24724262
P577publication date2019-04-26
P1476titleRotavirus NSP1 localizes in the nucleus to disrupt PML nuclear bodies during infection

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