| scholarly article | Q13442814 |
| P50 | author | John T Patton | Q67221097 |
| P2093 | author name string | Mario Barro | |
| P2860 | cites work | Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes | Q24311045 |
| Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation | Q24523761 | ||
| Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity | Q24599944 | ||
| Triggering the interferon response: the role of IRF-3 transcription factor | Q28137853 | ||
| Triggering the interferon antiviral response through an IKK-related pathway | Q28191761 | ||
| Comparison of the rotavirus nonstructural protein NSP1 (NS53) from different species by sequence analysis and northern blot hybridization | Q28244835 | ||
| Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease | Q29614208 | ||
| Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein | Q33810694 | ||
| Effect of intragenic rearrangement and changes in the 3' consensus sequence on NSP1 expression and rotavirus replication | Q33850456 | ||
| Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach | Q33895154 | ||
| A rotavirus vaccine for prevention of severe diarrhoea of infants and young children: development, utilization and withdrawal | Q34083368 | ||
| Respiratory syncytial virus: reverse genetics and vaccine strategies | Q34690910 | ||
| The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. | Q35105093 | ||
| The host response to West Nile Virus infection limits viral spread through the activation of the interferon regulatory factor 3 pathway | Q35122610 | ||
| Rotavirus replication: plus-sense templates for double-stranded RNA synthesis are made in viroplasms | Q35122641 | ||
| Deletion mapping of the rotavirus metalloprotein NS53 (NSP1): the conserved cysteine-rich region is essential for virus-specific RNA binding | Q36634428 | ||
| Murine rotavirus genes encoding outer capsid proteins VP4 and VP7 are not major determinants of host range restriction and virulence | Q36644973 | ||
| Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected] | Q37093418 | ||
| Cell-line-induced mutation of the rotavirus genome alters expression of an IRF3-interacting protein | Q37592530 | ||
| Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation | Q39683189 | ||
| Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1. | Q39684543 | ||
| Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection | Q39748053 | ||
| Gene expression pattern in Caco-2 cells following rotavirus infection. | Q39752806 | ||
| Nondefective rotavirus mutants with an NSP1 gene which has a deletion of 500 nucleotides, including a cysteine-rich zinc finger motif-encoding region (nucleotides 156 to 248), or which has a nonsense codon at nucleotides 153-155. | Q39874852 | ||
| Autocrine amplification of type I interferon gene expression mediated by interferon stimulated gene factor 3 (ISGF3). | Q41186845 | ||
| Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways | Q43586093 | ||
| Interferon gamma and interleukin 1, but not interferon alfa, inhibit rotavirus entry into human intestinal cell lines | Q46474616 | ||
| A Rotavirus Vaccine for Prevention of Severe Diarrhoea of Infants and Young Children: Development, Utilization and Withdrawal | Q56135136 | ||
| P4510 | describes a project that uses | Simian rotavirus A/SA11 | Q112242768 |
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Rotavirus | Q164778 |
| modulation by virus of host process | Q14818042 | ||
| Rotavirus non-structural protein 1 | Q24724262 | ||
| P304 | page(s) | 4114-9 | |
| P577 | publication date | 2005-03-15 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3 | |
| P478 | volume | 102 |
| Q35963818 | A novel mechanism for the inhibition of interferon regulatory factor-3-dependent gene expression by human respiratory syncytial virus NS1 protein |
| Q34059334 | Absence of genetic differences among G10P[11] rotaviruses associated with asymptomatic and symptomatic neonatal infections in Vellore, India. |
| Q43758073 | Analysis of rotavirus antigenemia in hematopoietic stem cell transplant recipients |
| Q40272095 | Attenuating mutations in the P/C gene of human parainfluenza virus type 1 (HPIV1) vaccine candidates abrogate the inhibition of both induction and signaling of type I interferon (IFN) by wild-type HPIV1. |
| Q55209357 | Basal interferon signaling and therapeutic use of interferons in controlling rotavirus infection in human intestinal cells and organoids. |
| Q39194807 | CHD6, a cellular repressor of influenza virus replication, is degraded in human alveolar epithelial cells and mice lungs during infection |
| Q54337036 | Calcineurin subunit B upregulates β-interferon production by phosphorylation of interferon regulatory factor 3 via Toll-like receptor 4. |
| Q35311960 | Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation |
| Q34874614 | Characterization of rotavirus RNAs that activate innate immune signaling through the RIG-I-like receptors |
| Q27478373 | Classical Swine Fever Virus Npro Interacts with Interferon Regulatory Factor 3 and Induces Its Proteasomal Degradation |
| Q94569692 | Comparative Sequence Analysis of Historic and Current Porcine Rotavirus C Strains and Their Pathogenesis in 3-Day-Old and 3-Week-Old Piglets |
| Q34077813 | Complete genome sequence analysis of candidate human rotavirus vaccine strains RV3 and 116E |
| Q36707759 | Coupling of rotavirus genome replication and capsid assembly. |
| Q28535489 | Cyclosporin a inhibits rotavirus replication and restores interferon-beta signaling pathway in vitro and in vivo |
| Q58546190 | DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus Through IL-1β Signalling |
| Q35785349 | Degrons at the C terminus of the pathogenic but not the nonpathogenic hantavirus G1 tail direct proteasomal degradation |
| Q47549718 | Distinct Effects of Type I and III Interferons on Enteric Viruses. |
| Q36003428 | Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections |
| Q34742076 | Diversity of interferon antagonist activities mediated by NSP1 proteins of different rotavirus strains |
| Q40352768 | Entirely plasmid-based reverse genetics system for rotaviruses |
| Q33511956 | Evolutionary dynamics of human rotaviruses: balancing reassortment with preferred genome constellations |
| Q90616737 | Generation of Recombinant Rotavirus Expressing NSP3-UnaG Fusion Protein by a Simplified Reverse Genetics System |
| Q35902623 | Genome heterogeneity of SA11 rotavirus due to reassortment with "O" agent |
| Q36166655 | Genome-Wide Evolutionary Analyses of G1P[8] Strains Isolated Before and After Rotavirus Vaccine Introduction |
| Q36949756 | Group A human rotavirus genomics: evidence that gene constellations are influenced by viral protein interactions |
| Q41993352 | HIV-1 Vpu does not degrade interferon regulatory factor 3. |
| Q33930417 | Hepatitis A virus suppresses RIG-I-mediated IRF-3 activation to block induction of beta interferon |
| Q37365391 | Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells |
| Q24336258 | Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I |
| Q40287161 | Human rhinovirus attenuates the type I interferon response by disrupting activation of interferon regulatory factor 3. |
| Q39816481 | IRF3 inhibition by rotavirus NSP1 is host cell and virus strain dependent but independent of NSP1 proteasomal degradation. |
| Q34126290 | Identification and characterization of a novel non-structural protein of bluetongue virus |
| Q27322192 | Identification of novel Ghanaian G8P[6] human-bovine reassortant rotavirus strain by next generation sequencing |
| Q33419823 | Immunization with recombinant SFTSV/NSs protein does not promote virus clearance in SFTSV-infected C57BL/6J mice |
| Q40051524 | Immunomodulatory potential of β-glucan as supportive treatment in porcine rotavirus enteritis |
| Q38161258 | Induction and control of the type I interferon pathway by Bluetongue virus |
| Q36050362 | Infection with the Persistent Murine Norovirus Strain MNV-S99 Suppresses IFN-Beta Release and Activation of Stat1 In Vitro |
| Q38170229 | Innate antiviral immune signaling, viral evasion and modulation by HIV-1. |
| Q36483624 | Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution. |
| Q84289542 | Innate immune responses to human rotavirus in the neonatal gnotobiotic piglet disease model |
| Q36497162 | Innate immune responses: crosstalk of signaling and regulation of gene transcription |
| Q60321331 | Interaction of rotavirus with human peripheral blood mononuclear cells: Plasmacytoid dendritic cells play a role in stimulating memory rotavirus specific T cells in vitro |
| Q34213447 | Intestinal epithelia activate anti-viral signaling via intracellular sensing of rotavirus structural components |
| Q39141025 | Japanese encephalitis virus non-coding RNA inhibits activation of interferon by blocking nuclear translocation of interferon regulatory factor 3. |
| Q24339399 | MAVS protein is attenuated by rotavirus nonstructural protein 1 |
| Q47222641 | MHC class I expression in intestinal cells is reduced by rotavirus infection and increased in bystander cells lacking rotavirus antigen |
| Q35133868 | Molecular epidemiology and genetic evolution of the whole genome of G3P[8] human rotavirus in Wuhan, China, from 2000 through 2013 |
| Q40191606 | Mouse hepatitis coronavirus A59 nucleocapsid protein is a type I interferon antagonist |
| Q38320849 | Mutations in toll-like receptor 3 are associated with elevated levels of rotavirus-specific IgG antibodies in IgA-deficient but not IgA-sufficient individuals |
| Q38907450 | NSP1 of human rotaviruses commonly inhibits NF-κB signalling by inducing β-TrCP degradation |
| Q59352330 | NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3 |
| Q33256133 | Natural products that reduce rotavirus infectivity identified by a cell-based moderate-throughput screening assay |
| Q33289420 | Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells |
| Q100524033 | PRV-encoded UL13 protein kinase acts as an antagonist of innate immunity by targeting IRF3-signaling pathways |
| Q43079549 | Permissive replication of homologous murine rotavirus in the mouse intestine is primarily regulated by VP4 and NSP1. |
| Q66678792 | Peste des Petits Ruminants Virus Nucleocapsid Protein Inhibits Beta Interferon Production by Interacting with IRF3 To Block Its Activation |
| Q38735239 | Porcine bocavirus NP1 protein suppresses type I IFN production by interfering with IRF3 DNA-binding activity. |
| Q40003152 | Porcine reproductive and respiratory syndrome virus (PRRSV) suppresses interferon-beta production by interfering with the RIG-I signaling pathway |
| Q24304218 | Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification |
| Q40223856 | Post-translational regulation of rotavirus protein NSP1 expression in mammalian cells. |
| Q35072342 | Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP. |
| Q24321688 | RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium |
| Q55234320 | RING-Domain E3 Ligase-Mediated Host-Virus Interactions: Orchestrating Immune Responses by the Host and Antagonizing Immune Defense by Viruses. |
| Q34101229 | Recombinant human parainfluenza virus type 2 with mutations in V that permit cellular interferon signaling are not attenuated in non-human primates. |
| Q28743106 | Reconciliation of rotavirus temperature-sensitive mutant collections and assignment of reassortment groups D, J, and K to genome segments |
| Q35990495 | Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction |
| Q38331589 | Regulation of gene expression by the NSP1 and NSP3 non-structural proteins of rotavirus |
| Q37414112 | Reovirus nonstructural protein sigma1s is required for establishment of viremia and systemic dissemination |
| Q35531278 | Replication of the rotavirus genome requires an active ubiquitin-proteasome system |
| Q34717075 | Reverse genetic generation of recombinant Zaire Ebola viruses containing disrupted IRF-3 inhibitory domains results in attenuated virus growth in vitro and higher levels of IRF-3 activation without inhibiting viral transcription or replication |
| Q41339221 | Role of interferon in homologous and heterologous rotavirus infection in the intestines and extraintestinal organs of suckling mice |
| Q40184517 | Role of interferon regulatory factor 3 in type I interferon responses in rotavirus-infected dendritic cells and fibroblasts |
| Q41998682 | Roles of VP4 and NSP1 in determining the distinctive replication capacities of simian rotavirus RRV and bovine rotavirus UK in the mouse biliary tract |
| Q114370821 | Rotaviral nonstructural protein 5 (NSP5) promotes proteasomal degradation of up-frameshift protein 1 (UPF1), a principal mediator of nonsense-mediated mRNA decay (NMD) pathway, to facilitate infection |
| Q37002502 | Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases |
| Q114371217 | Rotavirus NSP1 Inhibits Type I and Type III Interferon Induction |
| Q21090517 | Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism |
| Q24683021 | Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7 |
| Q114370948 | Rotavirus NSP1 localizes in the nucleus to disrupt PML nuclear bodies during infection |
| Q37123575 | Rotavirus NSP1 mediates degradation of interferon regulatory factors through targeting of the dimerization domain |
| Q37547591 | Rotavirus NSP1 protein inhibits interferon-mediated STAT1 activation |
| Q39113576 | Rotavirus NSP4 Triggers Secretion of Proinflammatory Cytokines from Macrophages via Toll-Like Receptor 2. |
| Q112229233 | Rotavirus Replication: the Role of Lipid Droplets |
| Q114371368 | Rotavirus Spike Protein VP4 Mediates Viroplasm Assembly by Association to Actin Filaments |
| Q38916023 | Rotavirus Strategies Against the Innate Antiviral System |
| Q59350438 | Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells |
| Q37582939 | Rotavirus and reovirus modulation of the interferon response |
| Q35260141 | Rotavirus antagonism of the innate immune response |
| Q37192229 | Rotavirus antagonizes cellular antiviral responses by inhibiting the nuclear accumulation of STAT1, STAT2, and NF-kappaB. |
| Q46605151 | Rotavirus degrades multiple type interferon receptors to inhibit IFN signaling and protects against mortality from endotoxin in suckling mice |
| Q38834140 | Rotavirus disrupts cytoplasmic P bodies during infection |
| Q36173819 | Rotavirus immune responses and correlates of protection |
| Q33614577 | Rotavirus infection activates dendritic cells from Peyer's patches in adult mice |
| Q39503784 | Rotavirus infection activates the UPR but modulates its activity |
| Q60934864 | Rotavirus infection beyond the gut |
| Q38996491 | Rotavirus inhibits IFN-induced STAT nuclear translocation by a mechanism that acts after STAT binding to importin-α. |
| Q24299094 | Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I |
| Q24610030 | Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection |
| Q34557876 | Rotavirus proteins: structure and assembly |
| Q39608666 | Rotavirus replication requires a functional proteasome for effective assembly of viroplasms |
| Q37588132 | Rotavirus strategies to evade host antiviral innate immunity |
| Q33598425 | Rotavirus structural proteins and dsRNA are required for the human primary plasmacytoid dendritic cell IFNalpha response |
| Q59360403 | Rotavirus vaccines: why continued investment in research is necessary |
| Q36525406 | Rotavirus variant replicates efficiently although encoding an aberrant NSP3 that fails to induce nuclear localization of poly(A)-binding protein |
| Q27313339 | Rotavirus viroplasm fusion and perinuclear localization are dynamic processes requiring stabilized microtubules |
| Q34278554 | Rotavirus-host cell interactions: an arms race |
| Q26996393 | Rotaviruses |
| Q40116816 | Selective inhibition of host cell signaling for rotavirus antivirals: PI3K/Akt/mTOR-mediated rotavirus pathogenesis |
| Q33644464 | Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors |
| Q35947754 | Semliki Forest virus nonstructural protein 2 is involved in suppression of the type I interferon response |
| Q57077884 | Signal transduction in the type I interferon system and viral countermeasures |
| Q37083338 | Silencing the alarms: Innate immune antagonism by rotavirus NSP1 and VP3 |
| Q37021757 | Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins. |
| Q34046154 | The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses |
| Q27477650 | The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal Degradation |
| Q92571706 | The Role of Nucleic Acid Sensing in Controlling Microbial and Autoimmune Disorders |
| Q28067379 | The Rotavirus Interferon Antagonist NSP1: Many Targets, Many Questions |
| Q27680413 | The Structure of Classical Swine Fever Virus Npro: A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction |
| Q27006920 | The battle between rotavirus and its host for control of the interferon signaling pathway |
| Q35076535 | The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3. |
| Q45035716 | The first complete genome sequence of a chicken group A rotavirus indicates independent evolution of mammalian and avian strains |
| Q41885839 | The genome segments of a group D rotavirus possess group A-like conserved termini but encode group-specific proteins |
| Q40184531 | The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 and, consequently, inhibits beta interferon promoter activity |
| Q36821757 | The interferon regulatory factor family in host defense: mechanism of action |
| Q36342106 | The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases |
| Q26860775 | The role of ubiquitylation in immune defence and pathogen evasion |
| Q36458510 | Toll-like receptors and innate antiviral immunity |
| Q27011462 | Toll-like receptors in antiviral innate immunity |
| Q36597749 | Two new monoclonal antibodies for biochemical and flow cytometric analyses of human interferon regulatory factor-3 activation, turnover, and depletion |
| Q36229423 | Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus |
| Q27481222 | Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus |
| Q37248029 | Variation in antagonism of the interferon response to rotavirus NSP1 results in differential infectivity in mouse embryonic fibroblasts |
| Q28743826 | Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3 |
| Q34130663 | Viral hijacking of the host ubiquitin system to evade interferon responses |
| Q36926779 | Viral stress-inducible genes. |
| Q39347085 | Vpu mediates depletion of interferon regulatory factor 3 during HIV infection by a lysosome-dependent mechanism |
| Q36953775 | Whole genome sequence and phylogenetic analyses reveal human rotavirus G3P[3] strains Ro1845 and HCR3A are examples of direct virion transmission of canine/feline rotaviruses to humans |
| Q28284962 | Zinc-binding domain of rotavirus NSP1 is required for proteasome-dependent degradation of IRF3 and autoregulatory NSP1 stability |
| Q57099973 | l-Isoleucine Administration Alleviates Rotavirus Infection and Immune Response in the Weaned Piglet Model |
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