The Rotavirus Interferon Antagonist NSP1: Many Targets, Many Questions

scientific article

The Rotavirus Interferon Antagonist NSP1: Many Targets, Many Questions is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1128/JVI.03068-15
P932PMC publication ID4934742
P698PubMed publication ID27009959

P50authorMichelle M ArnoldQ89053091
P2093author name stringMichelle M. Arnold
P2860cites workRotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonismQ21090517
Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3Q24555785
Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7Q24683021
RotavirusesQ26996393
2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysisQ34227701
Diversity of interferon antagonist activities mediated by NSP1 proteins of different rotavirus strainsQ34742076
Characterization of rotavirus RNAs that activate innate immune signaling through the RIG-I-like receptorsQ34874614
Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP.Q35072342
The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3.Q35076535
Rotavirus replication: plus-sense templates for double-stranded RNA synthesis are made in viroplasmsQ35122641
Rotavirus antagonism of the innate immune responseQ35260141
Silencing the alarms: Innate immune antagonism by rotavirus NSP1 and VP3Q37083338
Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunityQ37088604
Rotavirus NSP1 mediates degradation of interferon regulatory factors through targeting of the dimerization domainQ37123575
Variation in antagonism of the interferon response to rotavirus NSP1 results in differential infectivity in mouse embryonic fibroblastsQ37248029
Rotavirus NSP1 protein inhibits interferon-mediated STAT1 activationQ37547591
Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1.Q39684543
IRF3 inhibition by rotavirus NSP1 is host cell and virus strain dependent but independent of NSP1 proteasomal degradation.Q39816481
Nondefective rotavirus mutants with an NSP1 gene which has a deletion of 500 nucleotides, including a cysteine-rich zinc finger motif-encoding region (nucleotides 156 to 248), or which has a nonsense codon at nucleotides 153-155.Q39874852
Permissive replication of homologous murine rotavirus in the mouse intestine is primarily regulated by VP4 and NSP1.Q43079549
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectRotavirusQ164778
modulation by virus of host processQ14818042
Rotavirus non-structural protein 1Q24724262
P304page(s)5212-5215
P577publication date2016-05-12
P1433published inJournal of VirologyQ1251128
P1476titleThe Rotavirus Interferon Antagonist NSP1: Many Targets, Many Questions
P478volume90

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cites work (P2860)
Q37612580A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection
Q92259423Coding-Gene Coevolution Analysis of Rotavirus Proteins: A Bioinformatics and Statistical Approach
Q96768837Generation of recombinant rotaviruses from just 11 cDNAs encoding a viral genome
Q93165779Progressive Rotavirus Infection Downregulates Redox-Sensitive Transcription Factor Nrf2 and Nrf2-Driven Transcription Units
Q47588960Quantifying rotavirus kinetics in the REH tumor cell line using in vitro data.
Q55234320RING-Domain E3 Ligase-Mediated Host-Virus Interactions: Orchestrating Immune Responses by the Host and Antagonizing Immune Defense by Viruses.
Q114370871Rotavirus Interactions With Host Intestinal Epithelial Cells
Q114371217Rotavirus NSP1 Inhibits Type I and Type III Interferon Induction
Q92376467Rotavirus Species B Encodes a Functional Fusion-Associated Small Transmembrane Protein

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