Asymmetrical distribution of non-conserved regulatory sequences at PHOX2B is reflected at the ENCODE loci and illuminates a possible genome-wide trend

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Asymmetrical distribution of non-conserved regulatory sequences at PHOX2B is reflected at the ENCODE loci and illuminates a possible genome-wide trend is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1023503429
P356DOI10.1186/1471-2164-10-8
P8608Fatcat IDrelease_n2whbn5tkzaybmpbbx45v4ivki
P932PMC publication ID2630312
P698PubMed publication ID19128492
P5875ResearchGate publication ID23763326

P50authorDavid M McGaugheyQ58515863
P2093author name stringAndrew S McCallion
Jimmy L Huynh
Zachary E Stine
Ryan M Vinton
P2860cites workIdentification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectQ21061203
Highly conserved non-coding sequences are associated with vertebrate developmentQ21092819
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Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in congenital central hypoventilation syndromeQ24297880
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Ultraconservation identifies a small subset of extremely constrained developmental enhancersQ24648269
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FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatinQ24673476
Evaluation of the RET regulatory landscape reveals the biological relevance of a HSCR-implicated enhancerQ50748616
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Regulatory divergence modifies limb length between mammalsQ24677153
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A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactylyQ28184095
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The homeobox gene Phox2b is essential for the development of autonomic neural crest derivativesQ28505510
Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesisQ28594072
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Finding cis-regulatory elements using comparative genomics: some lessons from ENCODE dataQ33287630
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Evolution and functional classification of vertebrate gene desertsQ33596085
Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem diseaseQ33891844
Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastomaQ33909753
A common sex-dependent mutation in a RET enhancer underlies Hirschsprung disease risk.Q34411392
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Close sequence comparisons are sufficient to identify human cis-regulatory elements.Q34703070
Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patternsQ35251281
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Comparative genomic analysis as a tool for biological discoveryQ35608966
Comparative genomics at the vertebrate extremesQ35778678
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genomeQ35840707
Statistical analysis of the genomic distribution and correlation of regulatory elements in the ENCODE regionsQ35840712
Genomic regulatory networks and animal developmentQ36273945
Identification of active transcriptional regulatory modules by the functional assay of DNA from nucleosome-free regionsQ36700193
Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expressionQ40100963
Shuffling of cis-regulatory elements is a pervasive feature of the vertebrate lineageQ41852340
Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expressionQ41995414
Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2bQ42239743
The apolipoprotein(a) gene is regulated by sex hormones and acute-phase inducers in YAC transgenic mice.Q46431843
Phox2b function in the enteric nervous system is conserved in zebrafish and is sox10-dependentQ47074130
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)8
P577publication date2009-01-01
P1433published inBMC GenomicsQ15765854
P1476titleAsymmetrical distribution of non-conserved regulatory sequences at PHOX2B is reflected at the ENCODE loci and illuminates a possible genome-wide trend
P478volume10

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