| scholarly article | Q13442814 |
| P356 | DOI | 10.1006/BBRC.1995.1013 |
| P698 | PubMed publication ID | 7818555 |
| P2093 | author name string | G Bilbe | |
| T Kokubo | |||
| O Ishibashi | |||
| K Tezuka | |||
| M Kumegawa | |||
| T Inaoka | |||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | proteolysis | Q33123 |
| Cathepsin K | Q22679008 | ||
| P304 | page(s) | 89-96 | |
| P577 | publication date | 1995-01-05 | |
| P1433 | published in | Biochemical and Biophysical Research Communications | Q864228 |
| P1476 | title | Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone | |
| P478 | volume | 206 |
| Q35683586 | 6. Cathepsin K inhibitors: their potential as anti-osteoporosis agents |
| Q52101625 | A gene expression profile for endochondral bone formation: oligonucleotide microarrays establish novel connections between known genes and BMP-2-induced bone formation in mouse quadriceps. |
| Q73694174 | A peptidyl derivative structurally based on the inhibitory center of cystatin C inhibits bone resorption in vitro |
| Q36644762 | Analysis of crucial molecules involved in herniated discs and degenerative disc disease |
| Q44461789 | Arylaminoethyl amides as inhibitors of the cysteine protease cathepsin K-investigating P1' substituents |
| Q44578840 | Assay for cross-linked carboxyterminal telopeptide of type I collagen (ICTP) unlike CrossLaps assay reflects increased pathological degradation of type I collagen in rheumatoid arthritis |
| Q36748834 | Atypical CTSK transcripts and ARNT transcription read-through into CTSK. |
| Q36861164 | Autocatalytic activation of human cathepsin K. |
| Q41920146 | Biosynthesis and processing of cathepsin K in cultured human osteoclasts |
| Q28586755 | Cathepsin J, a novel murine cysteine protease of the papain family with a placenta-restricted expression |
| Q48348409 | Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice. |
| Q38666521 | Cathepsin K Inhibitors for Osteoporosis: Biology, Potential Clinical Utility, and Lessons Learned |
| Q43195946 | Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption |
| Q51013221 | Cathepsin K as a novel amyloid fibril protein in humans. |
| Q34265281 | Cathepsin K in treatment monitoring following intravenous zoledronic acid |
| Q36800896 | Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts |
| Q43775330 | Cathepsin K--a marker of macrophage differentiation? |
| Q37889119 | Cathepsin K: its skeletal actions and role as a therapeutic target in osteoporosis |
| Q24310097 | Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location |
| Q28138976 | Cathepsin expression during skeletal development |
| Q57786833 | Cathepsin-k expression in pulmonary lymphangioleiomyomatosis |
| Q33843319 | Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis. |
| Q73388269 | Characterization of the cathepsin B-like proteinases of Trichomonas tenax ATCC 30207 |
| Q41851855 | Chondroitin sulfate promotes activation of cathepsin K. |
| Q43687773 | Comparison in localization between cystatin C and cathepsin K in osteoclasts and other cells in mouse tibia epiphysis by immunolight and immunoelectron microscopy |
| Q44371315 | Complementary use of ion trap/time-of-flight mass spectrometry in combination with capillary high-pressure liquid chromatography: early characterization of in vivo metabolites of the cathepsin K inhibitor NVP-AAV490 in rat. |
| Q47955419 | Complete genomic structure of the mouse cathepsin K gene (Ctsk) and its localization next to the Arnt gene on mouse chromosome 3. |
| Q77370690 | Conformational studies on the specific cleavage site of Type I collagen (alpha-1) fragment (157-192) by cathepsins K and L by proton NMR spectroscopy |
| Q27734783 | Crystal structure of human osteoclast cathepsin K complex with E-64 |
| Q39124587 | Cystatin C in milk basic protein (MBP) and its inhibitory effect on bone resorption in vitro |
| Q41852264 | Cysteine cathepsin activity regulation by glycosaminoglycans |
| Q34713891 | Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease |
| Q43261393 | Diclofenac sodium inhibits NFkappaB transcription in osteoclasts |
| Q36506118 | Effect of angiotensin II receptor blocker on experimental periodontitis in a mouse model of Marfan syndrome |
| Q36349832 | Effect of fangchinoline on root resorption during rat orthodontic tooth movement |
| Q73327500 | Effects of an inhibitor of cathepsin L on bone resorption in thyroparathyroidectomized and ovariectomized rats |
| Q44428933 | Effects of beta-adrenergic agonists on bone-resorbing activity in human osteoclast-like cells |
| Q39420930 | Effects of brefeldin-A: potent inhibitor of intracellular protein transport on ultrastructure and resorptive function of cultured osteoclasts |
| Q86505152 | Effects of novel cathepsin K inhibitor ONO-5334 on bone resorption markers: a study of four sustained release formulations with different pharmacokinetic patterns |
| Q64235413 | Effects of the Cathepsin K Inhibitor ONO-5334 and Concomitant Use of ONO-5334 with Methotrexate on Collagen-Induced Arthritis in Cynomolgus Monkeys |
| Q39571989 | Enhanced anti-tumor activity and safety profile of targeted nano-scaled HPMA copolymer-alendronate-TNP-470 conjugate in the treatment of bone malignances |
| Q28583107 | Expression and Localization of Cathepsin K In Adult Rat Sertoli Cells1 |
| Q40963587 | Expression of cathepsin K in lung epithelial cells |
| Q34581004 | Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis |
| Q41840396 | Expression of human cathepsin K in Pichia pastoris and preliminary crystallographic studies of an inhibitor complex |
| Q52113302 | Expression of matrix metalloproteinase-9 mRNA and protein during deciduous tooth resorption in bovine odontoclasts. |
| Q43564115 | Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis |
| Q36270576 | Forced expression of human macrophage colony-stimulating factor in CD34+ cells promotes monocyte differentiation in vitro and in vivo but blunts osteoclastogenesis in vitro. |
| Q38309664 | Gene profiling of cathepsin K deficiency in atherogenesis: profibrotic but lipogenic. |
| Q28817275 | Genetic mechanisms of bone digestion and nutrient absorption in the bone-eating worm Osedax japonicus inferred from transcriptome and gene expression analyses |
| Q79501815 | High bone mineral density in pycnodysostotic patients with a novel mutation in the propeptide of cathepsin K |
| Q52587851 | Human Genetics of Sclerosing Bone Disorders. |
| Q40008809 | Human breast adenocarcinoma (MDA-231) and human lung squamous cell carcinoma (Hara) do not have the ability to cause bone resorption by themselves during the establishment of bone metastasis |
| Q28290432 | Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary molecular cloning, sequencing and tissue distribution |
| Q34422070 | Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T-lymphocytes |
| Q32021129 | Human cathepsin X: a novel cysteine protease of the papain family with a very short proregion and unique insertions |
| Q36324006 | Hyaluronan-CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9. |
| Q28248818 | Identification and characterization of cathepsin B as the cellular MARCKS cleaving enzyme |
| Q73553558 | Immunochemical characterization of assay for carboxyterminal telopeptide of human type I collagen: loss of antigenicity by treatment with cathepsin K |
| Q43763235 | Immunolocalization of vacuolar-type H+-ATPase, cathepsin K, matrix metalloproteinase-9, and receptor activator of NFkappaB ligand in odontoclasts during physiological root resorption of human deciduous teeth |
| Q36791739 | Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice |
| Q37219256 | In vitro method for the screening and monitoring of estrogen-deficiency osteoporosis by targeting peripheral circulating monocytes |
| Q44614849 | Inhibition of Drynariae Rhizoma extracts on bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts |
| Q43825780 | Inhibition of osteoclast differentiation and bone resorption by cathepsin K antisense oligonucleotides |
| Q32014632 | Large scale isolation of osteoclast-specific genes by an improved method involving the preparation of a subtracted cDNA library |
| Q50218797 | Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model. |
| Q28303355 | Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry |
| Q28579975 | Localization of rat cathepsin K in osteoclasts and resorption pits: inhibition of bone resorption and cathepsin K-activity by peptidyl vinyl sulfones |
| Q36147294 | Low dose of propranolol down-modulates bone resorption by inhibiting inflammation and osteoclast differentiation |
| Q36003737 | Low-density lipoprotein receptor deficiency causes impaired osteoclastogenesis and increased bone mass in mice because of defect in osteoclastic cell-cell fusion |
| Q38640619 | Markers of bone turnover in patients with epilepsy and their relationship to management of bone diseases induced by antiepileptic drugs. |
| Q38895940 | Marrow adipocyte-derived CXCL1 and CXCL2 contribute to osteolysis in metastatic prostate cancer |
| Q57082638 | Matrix Metalloproteinase-13 Is Highly Expressed in Destructive Periodontal Disease Activity |
| Q41985170 | Microscopic study on resorption of β-tricalcium phosphate materials by osteoclasts. |
| Q34769776 | Molecular and clinical analysis in a series of patients with Pyknodysostosis reveals some uncommon phenotypic findings |
| Q41121837 | Molecular aspects of osteoclast function |
| Q28295805 | Molecular cloning and sequence analysis of human preprocathepsin C |
| Q30696787 | Molecular cloning and structural and functional characterization of human cathepsin F, a new cysteine proteinase of the papain family with a long propeptide domain |
| Q36915183 | Molecular dynamics simulations of the catalytic pathway of a cysteine protease: a combined QM/MM study of human cathepsin K. |
| Q48060056 | Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development |
| Q28509398 | Mouse cathepsin M, a placenta-specific lysosomal cysteine protease related to cathepsins L and P |
| Q33897792 | Murine and human cathepsin Z: cDNA-cloning, characterization of the genes and chromosomal localization |
| Q28176872 | New functions of lactoferrin and beta-casein in mammalian milk as cysteine protease inhibitors |
| Q34573852 | Novel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescence |
| Q50065188 | Novel roles of glycosaminoglycans in the degradation of type I collagen by cathepsin K. |
| Q35062434 | ONO-5334, a cathepsin K inhibitor, improves bone strength by preferentially increasing cortical bone mass in ovariectomized rats |
| Q33936579 | Osteoclast formation and resorption |
| Q34127948 | Osteoclasts and odontoclasts: signaling pathways to development and disease |
| Q50202540 | Osteocytes Acidify Their Microenvironment in Response to PTHrP In Vitro and in Lactating Mice In Vivo. |
| Q36939677 | Osteoporosis - a current view of pharmacological prevention and treatment |
| Q44736425 | Ovarian cysteine proteinases in the teleost Fundulus heteroclitus: molecular cloning and gene expression during vitellogenesis and oocyte maturation |
| Q39669177 | PTH(1-34)-induced changes in RANKL and OPG expression by human PDL cells modify osteoclast biology in a co-culture model with RAW 264.7 cells |
| Q24538890 | Paternal uniparental disomy for chromosome 1 revealed by molecular analysis of a patient with pycnodysostosis |
| Q34275992 | Pathogenesis of rheumatoid arthritis: the role of synoviocytes |
| Q42981725 | Peptidyl vinyl sulphones: a new class of potent and selective cysteine protease inhibitors: S2P2 specificity of human cathepsin O2 in comparison with cathepsins S and L. |
| Q34391989 | Physiopathology of intratendinous calcific deposition |
| Q36914237 | Postmenopausal osteoporosis: the role of immune system cells |
| Q43517008 | Potent and selective cathepsin L inhibitors do not inhibit human osteoclast resorption in vitro |
| Q36136239 | Potential role of odanacatib in the treatment of osteoporosis |
| Q54047518 | Proteinase expression during differentiation of human osteoclasts in vitro. |
| Q33838178 | Proteinases in bone resorption: obvious and less obvious roles. |
| Q28280533 | Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification |
| Q38866853 | Punicalagin attenuates osteoclast differentiation by impairing NFATc1 expression and blocking Akt- and JNK-dependent pathways |
| Q43580089 | Quantification of the expression levels of lysosomal cysteine proteinases in purified human osteoclastic cells by competitive RT-PCR. |
| Q50215136 | Recent advances in osteoclast biology. |
| Q28265606 | Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs |
| Q42160515 | Retinoic acid directly stimulates osteoclastic bone resorption and gene expression of cathepsin K/OC-2 |
| Q34200518 | Role of the osteoclast at the bone-implant interface |
| Q36082866 | Signaling networks that control the lineage commitment and differentiation of bone cells |
| Q37714909 | Small molecules for bone diseases |
| Q57346608 | Stimuli-Responsive Polymer Delivery Systems |
| Q73077056 | Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo |
| Q77690449 | Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femur |
| Q34563752 | Targeting proteases: successes, failures and future prospects |
| Q48045091 | Tensile force on human macrophage cells promotes osteoclastogenesis through receptor activator of nuclear factor κB ligand induction. |
| Q37095379 | The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling |
| Q37287589 | The Role of Inflammatory Cytokines, the RANKL/OPG Axis, and the Immunoskeletal Interface in Physiological Bone Turnover and Osteoporosis |
| Q34122715 | The pathogenesis and prevention of joint damage in rheumatoid arthritis: advances from synovial biopsy and tissue analysis |
| Q48226512 | The polymethoxy flavonoid sudachitin suppresses inflammatory bone destruction by directly inhibiting osteoclastogenesis due to reduced ROS production and MAPK activation in osteoclast precursors. |
| Q36003689 | Transcriptome Reveals Cathepsin K in Periodontal Ligament Differentiation |
| Q73853199 | Tumor necrosis factor-alpha cooperates with receptor activator of nuclear factor kappaB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture |
| Q48759994 | WF14861, a new cathepsins B and L inhibitor produced by Colletotrichum sp. I. Taxonomy, production, purification and structure elucidation |
| Q48747041 | WF14865A and B, new cathepsins B and L inhibitors produced by Aphanoascus fulvescens. I. Taxonomy, production, purification and biological properties |
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